KEGG   DRUG: Lenrispodun
Entry
D11883                      Drug                                   
Name
Lenrispodun (USAN)
Formula
C29H26FN7O
Exact mass
507.2183
Mol weight
507.5614
Structure
Remark
Chemical structure group: DG03118
Efficacy
Antiparkinsonian, Phosphodiesterase 1 inhibitor
Comment
Treatment of Parkinson's disease, cardiovascular diseases, and other neurological and cardiovascular diseases
Target
PDE1 [HSA:5136 5153 5137] [KO:K13755]
Brite
Target-based classification of drugs [BR:br08310]
 Enzymes
  Hydrolases (EC3)
   Phosphodiesterases
    PDE1
     D11883  Lenrispodun (USAN)
Other DBs
CAS: 1160521-50-5
PDB-CCD: 4QJ[PDBj]
LinkDB
KCF data

ATOM        38
            1   N4y N    16.2283  -20.0670
            2   C8y C    16.2283  -21.4652
            3   N4y N    17.4167  -22.1642
            4   C8y C    18.6750  -21.4652
            5   C8y C    18.6750  -20.0670
            6   C8y C    17.4167  -19.3680
            7   C1a C    17.4167  -23.5623
            8   O5x O    19.8634  -22.1642
            9   C8y C    19.7236  -19.1583
            10  N4y N    19.0945  -17.8301
            11  N5x N    17.6964  -17.9699
            12  N1b N    20.9120  -19.8573
            13  C8y C    22.1004  -19.1583
            14  C8x C    23.2888  -19.8573
            15  C8x C    24.5471  -19.1583
            16  C8x C    24.5471  -17.7601
            17  C8x C    23.3587  -17.0611
            18  C8x C    22.1004  -17.7601
            19  C1b C    20.2829  -17.1310
            20  C8y C    20.2829  -15.7329
            21  C8x C    21.4936  -15.0338
            22  C8x C    21.4936  -13.6357
            23  C8y C    20.2829  -12.9365
            24  C8x C    19.0721  -13.6357
            25  C8x C    19.0721  -15.0338
            26  C8y C    20.2829  -11.5384
            27  N5x N    21.4936  -10.8394
            28  C8y C    21.4936   -9.4412
            29  C8x C    20.2829   -8.7422
            30  C8x C    19.0721   -9.4412
            31  C8x C    19.0721  -10.8394
            32  X   F    22.6875   -8.7518
            33  C1y C    14.8986  -19.6350
            34  C1y C    14.0768  -20.7661
            35  N2x N    14.8986  -21.8972
            36  C1x C    14.0768  -18.5038
            37  C1x C    12.7470  -18.9360
            38  C1x C    12.7470  -20.3341
BOND        44
            1     1   2 1
            2     2   3 1
            3     3   4 1
            4     4   5 1
            5     5   6 1
            6     1   6 1
            7     3   7 1
            8     4   8 2
            9     5   9 2
            10    9  10 1
            11   10  11 1
            12    6  11 2
            13    9  12 1
            14   12  13 1
            15   13  14 2
            16   14  15 1
            17   15  16 2
            18   16  17 1
            19   17  18 2
            20   13  18 1
            21   19  10 1
            22   19  20 1
            23   20  21 2
            24   21  22 1
            25   22  23 2
            26   23  24 1
            27   24  25 2
            28   20  25 1
            29   23  26 1
            30   26  27 2
            31   27  28 1
            32   28  29 2
            33   29  30 1
            34   30  31 2
            35   26  31 1
            36   28  32 1
            37    1  33 1
            38   33  34 1
            39   34  35 1
            40    2  35 2
            41   33  36 1
            42   36  37 1
            43   37  38 1
            44   34  38 1

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