| Entry |
|
|---|
| Name |
Esmethadone (USAN);
Dextromethadone |
|---|
| Formula |
C21H27NO
|
|---|
| Exact mass |
309.2093
|
|---|
| Mol weight |
309.44
|
|---|
| Structure |
|
|---|
| Class |
Neuropsychiatric agent
DG01498 NMDA receptor antagonist
|
|---|
| Remark |
|
|---|
| Efficacy |
Antidepressant, NMDA receptor antagonist |
|---|
| Comment |
Treatment of depression
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Brite |
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01498 NMDA receptor antagonist
DG03176 Esmethadone
D12214 Esmethadone
Target-based classification of drugs [BR:br08310]
Ion channels
Ligand-gated ion channels
Glutamate (ionotropic), NMDA
GRIN (NMDAR)
D12214 Esmethadone (USAN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01498 NMDA receptor antagonist
DG03176 Esmethadone
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 23
1 C8x C 15.4649 -17.4942
2 C8x C 15.4649 -18.8937
3 C8x C 16.6545 -19.5935
4 C8x C 17.8441 -18.8937
5 C8y C 17.8441 -17.4942
6 C8x C 16.6545 -16.8644
7 C8x C 20.1533 -18.8937
8 C8y C 20.1533 -17.4942
9 C1d C 18.9637 -16.8644
10 C8x C 21.3429 -19.5935
11 C8x C 22.5325 -18.8937
12 C8x C 22.5325 -17.4942
13 C8x C 21.3429 -16.8644
14 C1b C 18.9637 -15.4649
15 C1c C 20.1533 -14.7651
16 C5a C 17.0044 -15.7448
17 C1a C 21.3429 -15.4649
18 N1c N 20.1533 -13.5055
19 C1a C 21.3429 -12.8058
20 C1a C 18.9637 -12.8058
21 O5a O 17.0044 -14.4152
22 C1b C 15.8148 -16.4445
23 C1a C 14.6951 -15.7448
BOND 24
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 7 8 1
8 8 9 1
9 5 9 1
10 7 10 2
11 10 11 1
12 11 12 2
13 12 13 1
14 8 13 2
15 9 14 1
16 14 15 1
17 9 16 1
18 15 17 1 #Up
19 15 18 1
20 18 19 1
21 18 20 1
22 16 21 2
23 16 22 1
24 22 23 1
|
|---|
