| Entry |
|
|---|
| Name |
Zapnometinib (USAN/INN) |
|---|
| Formula |
C13H7ClF2INO2
|
|---|
| Exact mass |
408.9178
|
|---|
| Mol weight |
409.55
|
|---|
| Structure |
|
|---|
| Efficacy |
Antiviral, Mitogen-activated extracellular signal-regulated kinase (MEK) inhibitor |
|---|
| Comment |
Treatment of severe influenza, severe hanta virus diseases, and other respiratory viral diseases including COVID-19
|
|---|
| Target |
|
|---|
| Pathway |
|
|---|
| Brite |
Target-based classification of drugs [BR:br08310]
Protein kinases
Serine/threonine kinases
STE group
MAP2K (MEK)
D12473 Zapnometinib (USAN/INN)
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 20
1 C8x C 5.8800 -12.9500
2 C8x C 5.8800 -14.3500
3 C8y C 7.0924 -15.0500
4 C8y C 8.3049 -14.3500
5 C8y C 8.3049 -12.9500
6 C8y C 7.0924 -12.2500
7 N1b N 9.5360 -12.2390
8 C8y C 10.7412 -12.9347
9 C8x C 10.7416 -14.3496
10 C8x C 11.9542 -15.0493
11 C8y C 13.1665 -14.3489
12 C8x C 13.1660 -12.9339
13 C8y C 11.9534 -12.2343
14 C6a C 7.0924 -10.8502
15 O6a O 5.8632 -10.1403
16 O6a O 8.2880 -10.1598
17 X F 9.5360 -15.0610
18 X F 7.0924 -16.4498
19 X I 14.3747 -15.0460
20 X Cl 11.9532 -10.8501
BOND 21
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 5 7 1
8 7 8 1
9 8 9 2
10 9 10 1
11 10 11 2
12 11 12 1
13 12 13 2
14 8 13 1
15 6 14 1
16 14 15 2
17 14 16 1
18 4 17 1
19 3 18 1
20 11 19 1
21 13 20 1
|
|---|
