KEGG   DRUG: Nedosiran sodium
Entry
D12723                      Drug                                   
Name
Nedosiran sodium (USAN);
Rivfloza (TN)
Product
RIVFLOZA (Novo Nordisk)
Formula
C662H865F19N231O413P57S6.57Na
Exact mass
22285.1019
Mol weight
22295.55
Remark
ATC code: A16AX25
Product: D12723<US>
Efficacy
Hepatic lactate dehydrogenase level lowering agent
  Disease
Primary hyperoxaluria type 1 [DS:H00117]
  Type
RNA interference (RNAi) drug
Comment
Treatment of primary hyperoxaluria
Target
LDHA [HSA:3939] [KO:K00016] (mRNA)
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 A ALIMENTARY TRACT AND METABOLISM
  A16 OTHER ALIMENTARY TRACT AND METABOLISM PRODUCTS
   A16A OTHER ALIMENTARY TRACT AND METABOLISM PRODUCTS
    A16AX Various alimentary tract and metabolism products
     A16AX25 Nedosiran
      D12723  Nedosiran sodium (USAN) <US>
Target-based classification of drugs [BR:br08310]
 Enzymes
  Oxidoreductases (EC1)
   Dehydrogenases
    LDHA
     D12723  Nedosiran sodium (USAN) <US>
New drug approvals in the USA [br08319.html]
 New molecular entities and new therapeutic biological products
  D12723
New drug approvals in the USA, Europe and Japan [br08328.html]
 Approval dates by FDA, EMA and PMDA
  D12723
Other DBs
CAS: 2247026-22-6
PubChem: 497621136
LinkDB

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