Homo sapiens (human): 3939 Help Entry 3939              CDS       T01001                                  Symbol LDHA, GSD11, HEL-S-133P, LDHM, PIG19 Name (RefSeq) lactate dehydrogenase A   KO K00016   L-lactate dehydrogenase [EC:1.1.1.27] Organism hsa  Homo sapiens (human) Pathway hsa00010   Glycolysis / Gluconeogenesis hsa00270   Cysteine and methionine metabolism hsa00620   Pyruvate metabolism hsa00640   Propanoate metabolism hsa01100   Metabolic pathways hsa04066   HIF-1 signaling pathway hsa04922   Glucagon signaling pathway hsa05230   Central carbon metabolism in cancer Network nt06017  Glycogen metabolism   Element N00731   Glycolysis Disease H00069   Glycogen storage disease H01762   Muscle glycogen storage disease H01946   Glycogen storage disease type XI Brite KEGG Orthology (KO) [BR:hsa00001]  09100 Metabolism   09101 Carbohydrate metabolism    00010 Glycolysis / Gluconeogenesis     3939 (LDHA)    00620 Pyruvate metabolism     3939 (LDHA)    00640 Propanoate metabolism     3939 (LDHA)   09105 Amino acid metabolism    00270 Cysteine and methionine metabolism     3939 (LDHA)  09130 Environmental Information Processing   09132 Signal transduction    04066 HIF-1 signaling pathway     3939 (LDHA)  09150 Organismal Systems   09152 Endocrine system    04922 Glucagon signaling pathway     3939 (LDHA)  09160 Human Diseases   09161 Cancer: overview    05230 Central carbon metabolism in cancer     3939 (LDHA)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04147 Exosome [BR:hsa04147]     3939 (LDHA) Enzymes [BR:hsa01000]  1. Oxidoreductases   1.1  Acting on the CH-OH group of donors    1.1.1  With NAD+ or NADP+ as acceptor     1.1.1.27  L-lactate dehydrogenase      3939 (LDHA) Exosome [BR:hsa04147]  Exosomal proteins   Exosomal proteins of epithelial cells    3939 (LDHA)   Exosomal proteins of breast milk    3939 (LDHA) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Ldh_1_N Ldh_1_C Glyco_hydro_4 Pyr_redox_2 Glyco_hydro_4C Motif Other DBs NCBI-GeneID:  3939 NCBI-ProteinID:  NP_005557 OMIM:  150000 HGNC:  6535 Ensembl:  ENSG00000134333 Pharos:  P00338(Tchem) UniProt:  P00338 V9HWB9 Structure PDB LinkDB All DBs Position 11:18394563..18408425 Genome browser AA seq 332 aa AA seqDB search MATLKDQLIYNLLKEEQTPQNKITVVGVGAVGMACAISILMKDLADELALVDVIEDKLKG EMMDLQHGSLFLRTPKIVSGKDYNVTANSKLVIITAGARQQEGESRLNLVQRNVNIFKFI IPNVVKYSPNCKLLIVSNPVDILTYVAWKISGFPKNRVIGSGCNLDSARFRYLMGERLGV HPLSCHGWVLGEHGDSSVPVWSGMNVAGVSLKTLHPDLGTDKDKEQWKEVHKQVVESAYE VIKLKGYTSWAIGLSVADLAESIMKNLRRVHPVSTMIKGLYGIKDDVFLSVPCILGQNGI SDLVKVTLTSEEEARLKKSADTLWGIQKELQF NT seq 999 nt NT seq  +upstreamnt  +downstreamnt atggcaactctaaaggatcagctgatttataatcttctaaaggaagaacagaccccccag aataagattacagttgttggggttggtgctgttggcatggcctgtgccatcagtatctta atgaaggacttggcagatgaacttgctcttgttgatgtcatcgaagacaaattgaaggga gagatgatggatctccaacatggcagccttttccttagaacaccaaagattgtctctggc aaagactataatgtaactgcaaactccaagctggtcattatcacggctggggcacgtcag caagagggagaaagccgtcttaatttggtccagcgtaacgtgaacatctttaaattcatc attcctaatgttgtaaaatacagcccgaactgcaagttgcttattgtttcaaatccagtg gatatcttgacctacgtggcttggaagataagtggttttcccaaaaaccgtgttattgga agcggttgcaatctggattcagcccgattccgttacctaatgggggaaaggctgggagtt cacccattaagctgtcatgggtgggtccttggggaacatggagattccagtgtgcctgta tggagtggaatgaatgttgctggtgtctctctgaagactctgcacccagatttagggact gataaagataaggaacagtggaaagaggttcacaagcaggtggttgagagtgcttatgag gtgatcaaactcaaaggctacacatcctgggctattggactctctgtagcagatttggca gagagtataatgaagaatcttaggcgggtgcacccagtttccaccatgattaagggtctt tacggaataaaggatgatgtcttccttagtgttccttgcattttgggacagaatggaatc tcagaccttgtgaaggtgactctgacttctgaggaagaggcccgtttgaagaagagtgca gatacactttgggggatccaaaaggagctgcaattttaa

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