| Entry |
|
|---|
| Name |
Revumenib (USAN/INN) |
|---|
| Formula |
C32H47FN6O4S
|
|---|
| Exact mass |
630.3364
|
|---|
| Mol weight |
630.82
|
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| Structure |
|
|---|
| Remark |
| Product (DG03279): | D12729<US> |
|
|---|
| Efficacy |
Antineoplastic, Menin-MLL interaction inhibitor |
|---|
| Target |
|
|---|
| Pathway |
| hsa05202 | Transcriptional misregulation in cancer |
|
|---|
| Interaction |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
L ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
L01 ANTINEOPLASTIC AGENTS
L01X OTHER ANTINEOPLASTIC AGENTS
L01XX Other antineoplastic agents
L01XX87 Revumenib
D12728 Revumenib (USAN/INN)
Target-based classification of drugs [BR:br08310]
Not elsewhere classified
Cellular process
Chromatin
MEN1
D12728 Revumenib (USAN/INN)
|
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| Other DBs |
|
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| LinkDB |
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| KCF data |
ATOM 44
1 C8y C 23.6547 -14.2390
2 C8y C 22.4609 -13.5367
3 N1y N 21.2671 -14.2390
4 C1z C 19.3008 -14.2390
5 C1x C 20.2839 -13.2558
6 C1x C 20.2839 -15.2221
7 C1x C 17.1940 -15.4328
8 N1y N 16.4918 -14.2390
9 C1x C 17.1940 -13.0452
10 C1x C 18.5985 -13.0452
11 C1x C 18.5985 -15.4328
12 C1b C 15.0873 -14.2390
13 C1y C 14.3851 -15.4328
14 C1x C 15.0873 -16.6266
15 C1x C 14.3851 -17.8907
16 C1y C 12.9806 -17.8907
17 C1x C 12.2783 -16.6969
18 C1x C 12.9806 -15.4328
19 N1b N 12.2783 -19.0845
20 S4a S 10.8738 -19.0845
21 C1b C 9.4693 -19.0845
22 C1a C 8.7671 -20.2783
23 O3c O 10.8738 -17.6800
24 O3c O 10.8738 -20.4890
25 N5x N 22.4609 -12.1322
26 C8x C 23.6547 -11.4300
27 N5x N 24.9188 -12.1322
28 C8x C 24.9188 -13.5367
29 C8y C 27.3064 -17.7502
30 C8x C 27.3064 -16.3457
31 C8x C 26.1126 -15.6435
32 C8y C 24.8485 -16.3457
33 C8y C 24.8485 -17.7502
34 C8x C 26.1126 -18.4525
35 O2a O 23.6547 -15.6435
36 X F 28.5002 -18.4525
37 C5a C 23.6301 -18.4669
38 O5a O 22.4404 -17.7926
39 N1c N 23.6412 -19.8799
40 C1b C 24.8733 -20.5785
41 C1a C 26.0622 -19.8796
42 C1c C 22.4483 -20.5812
43 C1a C 21.2464 -19.8997
44 C1a C 22.4592 -21.9800
BOND 48
1 2 3 1
2 4 5 1
3 5 3 1
4 3 6 1
5 4 6 1
6 7 8 1
7 8 9 1
8 9 10 1
9 10 4 1
10 4 11 1
11 7 11 1
12 8 12 1
13 13 12 1 #Down
14 13 14 1
15 14 15 1
16 15 16 1
17 16 17 1
18 17 18 1
19 13 18 1
20 16 19 1 #Up
21 19 20 1
22 20 21 1
23 21 22 1
24 20 23 2
25 20 24 2
26 1 2 1
27 2 25 2
28 25 26 1
29 26 27 2
30 27 28 1
31 28 1 2
32 29 30 2
33 30 31 1
34 31 32 2
35 32 33 1
36 33 34 2
37 29 34 1
38 32 35 1
39 29 36 1
40 35 1 1
41 33 37 1
42 37 38 2
43 37 39 1
44 39 40 1
45 40 41 1
46 39 42 1
47 42 43 1
48 42 44 1
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