KEGG   DRUG: Eplontersen sodium
Entry
D12754                      Drug                                   
Name
Eplontersen sodium (USAN);
Wainua (TN)
Product
WAINUA (AstraZeneca Pharmaceuticals LP)
Formula
C296H417N77O156P20S13. 20Na
Exact mass
9040.614
Mol weight
9046.0161
Remark
ATC code: N07XX21
Product: D12754<US>
Efficacy
Amyloid fibril deposition inhibitor
  Disease
Polyneuropathy of hereditary transthyretin-mediated amyloidosis [DS:H00845]
  Type
Antisense oligonucleotide
Comment
Treatment of transthyretin-mediated amyloidosis
Target
TTR [HSA:7276] [KO:K20731] (mRNA)
  Pathway
hsa04918  Thyroid hormone synthesis
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N07 OTHER NERVOUS SYSTEM DRUGS
   N07X OTHER NERVOUS SYSTEM DRUGS
    N07XX Other nervous system drugs
     N07XX21 Eplontersen
      D12754  Eplontersen sodium (USAN) <US>
Target-based classification of drugs [BR:br08310]
 Transporters
  Other transporters
   Others
    TTR
     D12754  Eplontersen sodium (USAN) <US>
New drug approvals in the USA [br08319.html]
 New molecular entities and new therapeutic biological products
  D12754
New drug approvals in the USA, Europe and Japan [br08328.html]
 Approval dates by FDA, EMA and PMDA
  D12754
Other DBs
CAS: 2131025-75-5
LinkDB

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