| Entry |
|
|---|
| Name |
Obeldesivir (JAN/USAN/INN) |
|---|
| Formula |
C16H19N5O5
|
|---|
| Exact mass |
361.1386
|
|---|
| Mol weight |
361.35
|
|---|
| Structure |
|
|---|
| Class |
Antiviral
DG03174 Anti-SARS-CoV-2 agent
|
|---|
| Efficacy |
Antiviral, RNA polymerase inhibitor |
|---|
| Comment |
Active form of prodrug: GS-441524 [CPD: C22275]
nucleoside analog
Treatment of SARS-CoV-2 infection
|
|---|
| Target |
SARS coronavirus replicase [KO: K24149] |
|---|
| Pathway |
|
|---|
| Biosynthesis |
|
|---|
| Brite |
Drug groups [BR:br08330]
Antiviral
DG03174 Anti-SARS-CoV-2 agent
D12776 Obeldesivir
Antimicrobials [BR:br08307]
Antivirals
Genome replication inhibitor
Other inhibitor
D12776 Obeldesivir (JAN/USAN/INN)
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 26
1 C8y C 25.0309 -16.7106
2 N4y N 26.4293 -16.2911
3 C1z C 23.7724 -17.1301
4 C8x C 24.2618 -15.5220
5 C8y C 26.4293 -14.8927
6 N5x N 27.6879 -17.0602
7 O2x O 22.5838 -16.2911
8 C1y C 23.2830 -18.5285
9 C8x C 25.1009 -14.4033
10 C8y C 27.6879 -14.2634
11 C8x C 28.8765 -16.4309
12 C1y C 21.4651 -17.1301
13 C1y C 21.8846 -18.5285
14 O1a O 24.1919 -19.6472
15 N5x N 28.8765 -15.0325
16 N1a N 27.6879 -12.8651
17 O1a O 21.1155 -19.6472
18 C3b C 24.8911 -17.8293
19 N3a N 26.1496 -18.5285
20 C1b C 20.2765 -16.4309
21 O7a O 19.0878 -17.1301
22 C7a C 17.8950 -16.4544
23 C1c C 16.7090 -17.1524
24 O6a O 17.9533 -15.0505
25 C1a C 15.5057 -16.4709
26 C1a C 16.7206 -18.5500
BOND 28
1 1 2 1
2 3 1 1 #Up
3 1 4 2
4 2 5 1
5 2 6 1
6 3 7 1
7 3 8 1
8 4 9 1
9 5 10 1
10 6 11 2
11 7 12 1
12 8 13 1
13 8 14 1 #Down
14 10 15 2
15 10 16 1
16 13 17 1 #Down
17 5 9 2
18 11 15 1
19 12 13 1
20 3 18 1 #Down
21 18 19 3
22 20 21 1
23 12 20 1 #Up
24 21 22 1
25 22 23 1
26 22 24 2
27 23 25 1
28 23 26 1
|
|---|
