| Entry |
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| Name |
Risovalisib (INN) |
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| Formula |
C24H29F3N8O5S
|
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| Exact mass |
598.1934
|
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| Mol weight |
598.60
|
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| Structure |
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| Class |
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| Remark |
| Product (DG03302): | D12837<JP> |
|
|---|
| Efficacy |
Antineoplastic, Phosphatidylinositol 3-kinase inhibitor |
|---|
| Target |
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| Pathway |
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| Interaction |
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| Brite |
Drug groups [BR:br08330]
Antineoplastic
DG03139 PI3K inhibitor
DG03302 Risovalisib
D12836 Risovalisib
Metabolizing enzyme inducer
DG02891 CYP2B6 inducer
DG03302 Risovalisib
D12836 Risovalisib
DG01640 CYP2C8 inducer
DG03302 Risovalisib
D12836 Risovalisib
DG02886 CYP2C9 inducer
DG03302 Risovalisib
D12836 Risovalisib
DG02885 CYP2C19 inducer
DG03302 Risovalisib
D12836 Risovalisib
DG02853 CYP3A/CYP3A4 inducer
DG03302 Risovalisib
D12836 Risovalisib
Target-based classification of drugs [BR:br08310]
Enzymes
Transferases (EC2)
Phosphotransferase
PIK3CA
D12836 Risovalisib (INN)
Drug metabolizing enzymes and transporters [br08309.html]
Drug metabolizing enzymes
D12836
Drug groups [BR:br08330]
Antineoplastic
DG03139 PI3K inhibitor
DG03302 Risovalisib
Metabolizing enzyme inducer
DG02891 CYP2B6 inducer
DG03302 Risovalisib
DG01640 CYP2C8 inducer
DG03302 Risovalisib
DG02886 CYP2C9 inducer
DG03302 Risovalisib
DG02885 CYP2C19 inducer
DG03302 Risovalisib
DG02853 CYP3A/CYP3A4 inducer
DG03302 Risovalisib
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 41
1 N5x N 14.4900 -22.0500
2 C8y C 14.4900 -23.4500
3 N5x N 15.7024 -24.1500
4 N4y N 16.9149 -23.4500
5 C8y C 16.9149 -22.0500
6 C8y C 15.7024 -21.3500
7 C8x C 18.2464 -23.8826
8 C8y C 19.0693 -22.7500
9 C8x C 18.2464 -21.6174
10 N1y N 15.7024 -19.9502
11 C8y C 13.2776 -24.1500
12 C1b C 20.4400 -22.7500
13 N1y N 21.1400 -21.5376
14 C1x C 22.5398 -21.5376
15 C1x C 23.2398 -20.3251
16 N1y N 22.5398 -19.1127
17 C1x C 21.1400 -19.1127
18 C1x C 20.4400 -20.3251
19 S4a S 23.2410 -17.8982
20 C1a C 23.9410 -16.6857
21 O3c O 24.4535 -18.5982
22 O3c O 22.0286 -17.1982
23 C1x C 16.8980 -19.2597
24 C1x C 16.8978 -17.8597
25 O2x O 15.6853 -17.1599
26 C1x C 14.4898 -17.8503
27 C1x C 14.4899 -19.2503
28 C8x C 12.0821 -23.4596
29 N5x N 10.8696 -24.1595
30 C8y C 10.8694 -25.5595
31 C8x C 12.0649 -26.2499
32 C8y C 13.2774 -25.5500
33 C1d C 14.5066 -26.2600
34 X F 15.7190 -26.9600
35 X F 15.2066 -25.0476
36 X F 13.8066 -27.4725
37 N1b N 9.6466 -26.2654
38 C7a C 8.4377 -25.5674
39 O7a O 7.2570 -26.2490
40 O6a O 8.4373 -24.1504
41 C1a C 6.0624 -25.5591
BOND 45
1 1 2 1
2 2 3 2
3 3 4 1
4 4 5 1
5 5 6 1
6 1 6 2
7 4 7 1
8 7 8 2
9 8 9 1
10 5 9 2
11 6 10 1
12 2 11 1
13 8 12 1
14 12 13 1
15 13 14 1
16 14 15 1
17 15 16 1
18 16 17 1
19 17 18 1
20 13 18 1
21 16 19 1
22 19 20 1
23 19 21 2
24 19 22 2
25 10 23 1
26 23 24 1
27 24 25 1
28 25 26 1
29 26 27 1
30 10 27 1
31 11 28 2
32 28 29 1
33 29 30 2
34 30 31 1
35 31 32 2
36 11 32 1
37 32 33 1
38 33 34 1
39 33 35 1
40 33 36 1
41 30 37 1
42 37 38 1
43 38 39 1
44 38 40 2
45 39 41 1
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