| Entry |
|
|---|
| Name |
Benzgalantamine (USAN/INN) |
|---|
| Formula |
C24H25NO4
|
|---|
| Exact mass |
391.1784
|
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| Mol weight |
391.46
|
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| Structure |
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|---|
| Class |
Neuropsychiatric agent
DG01595 Cholinesterase inhibitor
DG01593 Acetylcholinesterase inhibitor
DG01968 Antidementia agent
|
|---|
| Remark |
| Product (DG03314): | D12931<US> |
|
|---|
| Efficacy |
Dementia therapeutic agent, Acetylcholinesterase inhibitor |
|---|
| Comment |
Treatment of Alzheimer's disease and memory/ cognitive impairment
Active form of prodrug: Galantamine [DR: D04292]
|
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| Target |
|
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| Pathway |
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| Interaction |
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| Brite |
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01595 Cholinesterase inhibitor
DG01593 Acetylcholinesterase inhibitor
DG03314 Benzgalantamine
D12930 Benzgalantamine
DG01968 Antidementia agent
DG03314 Benzgalantamine
D12930 Benzgalantamine
Target-based classification of drugs [BR:br08310]
Enzymes
Hydrolases (EC3)
Carboxylic-ester hydrolases
ACHE
D12930 Benzgalantamine (USAN/INN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01595 Cholinesterase inhibitor
DG01593 Acetylcholinesterase inhibitor
DG03314 Benzgalantamine
DG01968 Antidementia agent
DG03314 Benzgalantamine
|
|---|
| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 29
1 C8y C 19.3149 -18.2652
2 C1x C 20.3646 -19.0350
3 N1y N 21.6942 -18.7550
4 C1x C 22.2541 -17.4954
5 C8y C 19.3149 -16.8655
6 C1x C 21.6942 -16.3057
7 C1z C 20.3646 -15.8158
8 C1a C 22.6040 -19.8047
9 C8x C 18.1252 -18.9650
10 C8x C 16.9355 -18.2652
11 C8y C 16.9355 -16.8655
12 C8y C 18.1252 -16.1657
13 O2a O 15.7458 -16.2357
14 O2x O 18.4751 -14.5561
15 C1y C 19.8747 -14.4862
16 C1x C 20.5046 -13.3665
17 C1y C 21.9042 -13.3665
18 C2x C 22.6040 -14.5561
19 C2x C 21.9042 -15.8158
20 O7a O 22.6040 -12.1068
21 C1a C 14.5561 -17.0055
22 C7a C 24.0098 -12.0836
23 C8y C 24.7415 -13.3037
24 O6a O 24.6785 -10.8799
25 C8x C 24.0563 -14.6080
26 C8x C 24.7767 -15.7385
27 C8x C 26.1765 -15.7849
28 C8x C 26.7917 -14.4806
29 C8x C 26.1413 -13.2801
BOND 33
1 3 4 1
2 1 5 2
3 4 6 1
4 2 3 1
5 5 7 1
6 1 2 1
7 7 6 1 #Down
8 3 8 1
9 1 9 1
10 9 10 2
11 10 11 1
12 11 12 2
13 5 12 1
14 11 13 1
15 12 14 1
16 14 15 1
17 7 15 1
18 15 16 1
19 16 17 1
20 17 18 1
21 7 19 1
22 19 18 2
23 17 20 1 #Up
24 13 21 1
25 20 22 1
26 22 23 1
27 22 24 2
28 23 25 2
29 25 26 1
30 26 27 2
31 27 28 1
32 28 29 2
33 23 29 1
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