| Entry |
|
|---|
| Name |
Ceperognastat (USAN) |
|---|
| Formula |
C16H22FN5O3S
|
|---|
| Exact mass |
383.1427
|
|---|
| Mol weight |
383.44
|
|---|
| Structure |
|
|---|
| Efficacy |
Neurodegenerative diseases agent, o-GlcNAcase inhibitor, Tau protein aggregation inhibitor |
|---|
| Comment |
Treatment of neurodegenerative diseases and disorders, such as Alzheimer's disease
|
|---|
| Target |
|
|---|
| Brite |
Target-based classification of drugs [BR:br08310]
Enzymes
Hydrolases (EC3)
Glycosidases
OGA
D12955 Ceperognastat (USAN)
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 26
1 C1x C 22.1900 -14.9800
2 C1y C 22.1900 -16.3800
3 C1x C 23.3800 -17.0800
4 C1x C 24.6400 -16.3800
5 N1y N 24.6400 -14.9800
6 C1y C 23.3800 -14.2800
7 C1b C 25.8300 -14.2800
8 C8y C 27.0200 -14.9800
9 C8y C 27.5100 -16.3100
10 N5x N 28.9100 -16.3100
11 C8y C 29.3300 -14.9800
12 S2x S 28.2100 -14.1400
13 X F 26.6700 -17.4300
14 N1b N 30.5200 -14.2800
15 C5a C 31.7100 -14.9800
16 C1a C 32.9000 -14.2800
17 O5a O 31.7100 -16.3800
18 C1a C 23.3800 -12.8800
19 O2a O 21.0000 -17.0800
20 C1b C 19.8100 -16.3800
21 C8y C 18.6200 -17.0800
22 N5x N 17.5000 -16.2400
23 C8y C 16.3800 -17.0100
24 O2x O 16.8000 -18.3400
25 N5x N 18.1300 -18.3400
26 C1a C 15.1900 -16.3100
BOND 28
1 1 2 1
2 2 3 1
3 3 4 1
4 4 5 1
5 5 6 1
6 1 6 1
7 5 7 1
8 7 8 1
9 8 9 2
10 9 10 1
11 10 11 2
12 11 12 1
13 8 12 1
14 9 13 1
15 14 15 1
16 14 11 1
17 15 16 1
18 15 17 2
19 6 18 1 #Down
20 2 19 1 #Down
21 19 20 1
22 20 21 1
23 21 22 1
24 22 23 2
25 23 24 1
26 24 25 1
27 21 25 2
28 26 23 1
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|---|
