Homo sapiens (human): 10724 Help Entry 10724             CDS       T01001                                  Symbol OGA, MEA5, MGEA5, NCOAT Name (RefSeq) O-GlcNAcase   KO K15719   protein O-GlcNAcase / histone acetyltransferase [EC:3.2.1.169 2.3.1.48] Organism hsa  Homo sapiens (human) Pathway hsa04931   Insulin resistance Drug target Ceperognastat:  D12955 Brite KEGG Orthology (KO) [BR:hsa00001]  09160 Human Diseases   09167 Endocrine and metabolic disease    04931 Insulin resistance     10724 (OGA) Enzymes [BR:hsa01000]  2. Transferases   2.3  Acyltransferases    2.3.1  Transferring groups other than aminoacyl groups     2.3.1.48  histone acetyltransferase      10724 (OGA)  3. Hydrolases   3.2  Glycosylases    3.2.1  Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds     3.2.1.169  protein O-GlcNAcase      10724 (OGA) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  NAGidase Motif Other DBs NCBI-GeneID:  10724 NCBI-ProteinID:  NP_036347 OMIM:  604039 HGNC:  7056 Ensembl:  ENSG00000198408 UniProt:  O60502 Structure PDBPDBj LinkDB All DBs Position 10:complement(101784450..101818444) Genome browser AA seq 916 aa AA seqDB search MVQKESQATLEERESELSSNPAASAGASLEPPAAPAPGEDNPAGAGGAAVAGAAGGARRF LCGVVEGFYGRPWVMEQRKELFRRLQKWELNTYLYAPKDDYKHRMFWREMYSVEEAEQLM TLISAAREYEIEFIYAISPGLDITFSNPKEVSTLKRKLDQVSQFGCRSFALLFDDIDHNM CAADKEVFSSFAHAQVSITNEIYQYLGEPETFLFCPTEYCGTFCYPNVSQSPYLRTVGEK LLPGIEVLWTGPKVVSKEIPVESIEEVSKIIKRAPVIWDNIHANDYDQKRLFLGPYKGRS TELIPRLKGVLTNPNCEFEANYVAIHTLATWYKSNMNGVRKDVVMTDSEDSTVSIQIKLE NEGSDEDIETDVLYSPQMALKLALTEWLQEFGVPHQYSSRQVAHSGAKASVVDGTPLVAA PSLNATTVVTTVYQEPIMSQGAALSGEPTTLTKEEEKKQPDEEPMDMVVEKQEETDHKND NQILSEIVEAKMAEELKPMDTDKESIAESKSPEMSMQEDCISDIAPMQTDEQTNKEQFVP GPNEKPLYTAEPVTLEDLQLLADLFYLPYEHGPKGAQMLREFQWLRANSSVVSVNCKGKD SEKIEEWRSRAAKFEEMCGLVMGMFTRLSNCANRTILYDMYSYVWDIKSIMSMVKSFVQW LGCRSHSSAQFLIGDQEPWAFRGGLAGEFQRLLPIDGANDLFFQPPPLTPTSKVYTIRPY FPKDEASVYKICREMYDDGVGLPFQSQPDLIGDKLVGGLLSLSLDYCFVLEDEDGICGYA LGTVDVTPFIKKCKISWIPFMQEKYTKPNGDKELSEAEKIMLSFHEEQEVLPETFLANFP SLIKMDIHKKVTDPSVAKSMMACLLSSLKANGSRGAFCEVRPDDKRILEFYSKLGCFEIA KMEGFPKDVVILGRSL NT seq 2751 nt NT seq  +upstreamnt  +downstreamnt atggtgcagaaggagagtcaagcgacgttggaggagcgggagagcgagctcagctccaac cctgccgcctctgcgggggcatcgctggagccgccggcagctccggcacccggagaagac aaccccgccggggctgggggagcggcggtggccggggctgcaggaggggctcggcggttc ctctgcggtgtggtggaaggattttatggaagaccttgggttatggaacagagaaaagaa ctctttagaaggctccagaaatgggaattaaatacatacttgtatgccccaaaagatgac tacaaacataggatgttttggcgagagatgtattcagtggaggaagctgagcaacttatg actctcatctctgctgcacgagaatatgagatagagttcatctatgcgatctcacctgga ttggatatcactttttctaaccccaaggaagtatccacattgaaacgtaaattggaccag gtttctcagtttgggtgcagatcatttgctttgctttttgatgatatagaccataatatg tgtgcagcagacaaagaggtattcagttcttttgctcatgcccaagtctccatcacaaat gaaatctatcagtacctaggagagccagaaactttcctcttctgtcccacagaatactgt ggcactttctgttatccaaatgtgtctcagtctccatatttaaggactgtgggtgaaaag cttctacctggaattgaagtgctttggacaggtcccaaagttgtttctaaagaaattcca gtagagtccatcgaagaggtttctaagattattaagagagctccagtaatctgggataac attcatgctaatgattatgatcagaagagactgtttctgggcccgtacaaaggaagatcc acagaactcatcccacggttaaaaggagtcctcactaatccaaattgtgaatttgaagcc aactacgttgctatccacacccttgccacctggtacaaatcaaacatgaatggagtgaga aaagatgtagtgatgactgacagtgaagatagtactgtgtccatccagataaaattagaa aatgaaggcagtgatgaagatattgaaactgatgtactctatagtccacagatggctcta aagctagcattaacagaatggttgcaagagtttggtgtgcctcatcaatacagcagtagg caagttgcacacagtggagctaaagcaagtgtagttgatgggactcctttagttgcagca ccctctttaaatgccacaaccgtagtaacaacagtttatcaggagcccattatgagccag ggagcagccttgagtggtgagcctactactctgaccaaggaagaagaaaagaaacagcct gatgaagaacccatggacatggtggtggaaaaacaagaagaaacggaccacaagaatgac aatcaaatactgagtgaaattgttgaagcgaaaatggcagaggaattgaaaccaatggac actgataaagagagcatagctgaatcaaaatccccagagatgtccatgcaagaagattgt attagtgacattgcccccatgcaaactgatgaacagacaaacaaggagcagtttgtgcca ggtccaaatgaaaagcctttgtacactgcggaaccagtgaccctggaggatttgcagtta cttgctgatctattctaccttccttacgagcatggacccaaaggagcacagatgttacgg gaatttcaatggcttcgagcaaatagtagtgttgtcagtgtcaattgcaaaggaaaagac tctgaaaaaattgaagaatggcggtcacgagcagccaagtttgaagagatgtgtggacta gtgatgggaatgttcactcggctctccaattgtgccaacaggacaattctttatgacatg tactcctatgtttgggatatcaagagtataatgtctatggtgaagtcttttgtacagtgg ttagggtgtcgtagtcattcttcagcacaattcttaattggagaccaagaaccctgggcc tttagaggtggtctagcaggagagttccagcgtttgctgccaattgatggggcaaatgat ctcttttttcagccacctccactgactcctacctccaaagtttatactatcagaccttat tttcctaaggatgaggcatccgtgtacaagatttgcagagaaatgtatgacgatggagtg ggtttaccctttcaaagtcagcctgatcttattggagacaagttagtaggagggctgctt tccctcagcctggattactgctttgtcctagaagatgaagatggcatatgtggttatgcc ttgggcactgtagatgtgaccccctttattaaaaaatgtaaaatttcctggatccccttc atgcaggagaagtataccaagccaaatggtgacaaggaactctctgaggctgagaaaata atgttgagtttccatgaagaacaggaagtactgccagaaactttccttgctaatttccct tctctgataaagatggacattcacaaaaaagtaactgacccaagtgtggccaaaagcatg atggcttgcctcctgtcttcactgaaggctaatggctcccggggagctttctgtgaagtg agaccagatgataaaagaattctggaattttacagcaagttaggatgttttgaaattgca aaaatggaaggatttccaaaggatgtggttatacttggtcggagcctgtga

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