| Entry |
|
|---|
| Name |
Vosilasarm (USAN/INN) |
|---|
| Formula |
C20H16ClN5O2
|
|---|
| Exact mass |
393.0993
|
|---|
| Mol weight |
393.82
|
|---|
| Structure |
|
|---|
| Efficacy |
Antineoplastic, Selective androgen receptor modulator (SARM) |
|---|
| Comment |
Treatment of estrogen receptor and androgen receptor-positive breast cancer
Nonsteroidal
|
|---|
| Target |
|
|---|
| Pathway |
|
|---|
| Brite |
Target-based classification of drugs [BR:br08310]
Nuclear receptors
Estrogen like receptors
3-Ketosteroid receptor
NR3C4 (AR)
D13046 Vosilasarm (USAN/INN)
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 28
1 C8y C 13.9300 -17.9200
2 C8x C 13.9300 -16.5200
3 C8x C 15.1200 -15.8200
4 C8y C 16.3800 -16.5200
5 C8x C 16.3800 -17.9200
6 C8x C 15.1200 -18.6200
7 C3b C 12.7400 -18.6200
8 N3a N 11.4800 -19.3200
9 C8y C 17.5700 -15.8200
10 N5x N 17.9900 -14.4900
11 N5x N 19.3900 -14.4900
12 C8y C 19.8100 -15.7500
13 O2x O 18.6900 -16.5900
14 C1c C 21.0000 -16.4500
15 N1b N 22.1900 -15.7500
16 C8y C 23.3800 -16.4500
17 C8y C 24.5700 -15.7500
18 C8y C 25.8300 -16.4500
19 C8y C 25.8300 -17.8500
20 C8x C 24.5700 -18.5500
21 C8x C 23.3800 -17.8500
22 C3b C 27.0200 -18.5500
23 N3a N 28.2800 -19.2500
24 X Cl 27.0200 -15.7500
25 C1a C 24.5700 -14.3500
26 C1c C 21.0000 -17.8500
27 C1a C 22.1900 -18.5500
28 O1a O 19.8100 -18.5500
BOND 30
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 1 7 1
8 7 8 3
9 4 9 1
10 9 10 2
11 10 11 1
12 11 12 2
13 12 13 1
14 9 13 1
15 14 15 1 #Down
16 14 12 1
17 15 16 1
18 16 17 2
19 17 18 1
20 18 19 2
21 19 20 1
22 20 21 2
23 16 21 1
24 19 22 1
25 22 23 3
26 18 24 1
27 17 25 1
28 14 26 1
29 26 27 1
30 26 28 1 #Down
|
|---|
