KEGG   DRUG: Osavampator
Entry
D13050                      Drug                                   
Name
Osavampator (USAN/INN)
Formula
C19H23N3O3S
Exact mass
373.1460
Mol weight
373.47
Structure
Class
Unclassified
 DG03344  AMPA receptor modulator
Efficacy
Antidepressant, AMPA receptor positive allosteric modulator
Comment
Treatment of major depressive disorder
Target
GRIA [HSA:2890 2891 2892 2893] [KO:K05197 K05198 K05199 K05200]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04724  Glutamatergic synapse
hsa04728  Dopaminergic synapse
Brite
Drug groups [BR:br08330]
 Unclassified
  DG03344  AMPA receptor modulator
   D13050  Osavampator
Target-based classification of drugs [BR:br08310]
 Ion channels
  Ligand-gated ion channels
   Glutamate (ionotropic), non-NMDA
    GRIA
     D13050  Osavampator (USAN/INN)
Other DBs
PubChem: 505917323
LinkDB
KCF data

ATOM        26
            1   C8y C     9.1000  -12.2500
            2   N5x N     9.1000  -13.6500
            3   C8y C    10.3124  -14.3500
            4   C8y C    11.5249  -13.6500
            5   N4y N    11.5249  -12.2500
            6   C8x C    10.3124  -11.5500
            7   N2x N    12.7373  -14.3500
            8   S2x S    13.9497  -13.6500
            9   C1x C    13.9497  -12.2500
            10  C1x C    12.7373  -11.5500
            11  C8y C    10.3124  -15.7498
            12  C8x C     9.0832  -16.4597
            13  C8x C     9.0834  -17.8597
            14  C8y C    10.2959  -18.5596
            15  C8x C    11.5251  -17.8497
            16  C8x C    11.5249  -16.4497
            17  O2a O    10.2960  -19.9500
            18  C1a C     7.8876  -11.5500
            19  O3c O    13.9497  -15.0500
            20  O3c O    15.1622  -12.9500
            21  C1y C     9.0791  -20.6527
            22  C1x C     7.8813  -19.9611
            23  C1x C     6.6688  -20.6610
            24  C1x C     6.6688  -22.0610
            25  C1x C     7.8666  -22.7526
            26  C1x C     9.0791  -22.0527
BOND        29
            1     1   2 1
            2     2   3 2
            3     3   4 1
            4     4   5 1
            5     5   6 1
            6     1   6 2
            7     4   7 2
            8     7   8 1
            9     8   9 1
            10    9  10 1
            11    5  10 1
            12    3  11 1
            13   11  12 2
            14   12  13 1
            15   13  14 2
            16   14  15 1
            17   15  16 2
            18   11  16 1
            19   14  17 1
            20    1  18 1
            21    8  19 2
            22    8  20 2
            23   17  21 1
            24   21  22 1
            25   22  23 1
            26   23  24 1
            27   24  25 1
            28   25  26 1
            29   21  26 1

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