| Entry |
|
|---|
| Name |
Pilavapadin phosphate (USAN) |
|---|
| Formula |
C19H23F4N3O. H3PO4
|
|---|
| Exact mass |
483.1546
|
|---|
| Mol weight |
483.39
|
|---|
| Structure |
|
|---|
| Remark |
|
|---|
| Efficacy |
Pain relief, Adaptor protein 2-associated kinase 1 inhibitor |
|---|
| Comment |
Treatment of neuropathic pain including diabetic peripheral neuropathy and postherpetic neuralgia
|
|---|
| Target |
|
|---|
| Brite |
Target-based classification of drugs [BR:br08310]
Protein kinases
Serine/threonine kinases
Other
AAK1
D13081 Pilavapadin phosphate (USAN)
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 32
1 C8y C 13.1297 -17.0406
2 N5x N 13.1297 -18.4374
3 C8x C 14.3868 -19.1358
4 C8x C 15.5740 -18.4374
5 C8y C 15.5740 -17.0406
6 C8x C 14.3868 -16.3422
7 C8y C 16.8311 -16.3422
8 N5x N 18.0183 -17.0406
9 C8y C 19.2056 -16.3422
10 C8y C 19.2056 -14.8756
11 C8x C 18.0183 -14.1773
12 C8x C 16.8311 -14.9455
13 C1c C 20.4627 -17.0406
14 X F 21.6499 -16.3422
15 X F 20.4627 -18.4374
16 O2a O 20.4627 -14.1773
17 C1b C 21.6499 -14.8756
18 C1d C 22.8372 -14.2471
19 C1b C 24.0244 -14.9455
20 C1c C 25.2117 -14.2471
21 C1a C 26.3989 -14.9455
22 C1a C 25.2117 -12.8503
23 N1a N 22.1388 -12.9900
24 C1a C 23.5355 -12.9900
25 C1c C 11.9424 -16.3422
26 X F 10.7552 -17.0406
27 X F 11.9424 -14.9455
28 P1b P 30.1700 -17.5700
29 O1c O 30.1700 -16.1700
30 O1c O 28.7700 -17.5700
31 O1c O 31.5700 -17.5700
32 O1c O 30.1700 -18.9700
BOND 32
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 5 7 1
8 7 8 2
9 8 9 1
10 9 10 2
11 10 11 1
12 11 12 2
13 7 12 1
14 9 13 1
15 13 14 1
16 13 15 1
17 10 16 1
18 16 17 1
19 17 18 1
20 18 19 1
21 19 20 1
22 20 21 1
23 20 22 1
24 18 23 1 #Up
25 18 24 1 #Down
26 1 25 1
27 25 26 1
28 25 27 1
29 28 29 2
30 28 30 1
31 28 31 1
32 28 32 1
|
|---|
