Homo sapiens (human): 22848
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Entry
22848 CDS
T01001
Symbol
AAK1
Name
(RefSeq) AP2 associated kinase 1
KO
K08853
AP2-associated kinase [EC:
2.7.11.1
]
Organism
hsa
Homo sapiens (human)
Drug target
Pilavapadin (
DG03336
):
D13080
D13081
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
hsa01001
]
22848 (AAK1)
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
hsa04131
]
22848 (AAK1)
Enzymes [BR:
hsa01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
22848 (AAK1)
Protein kinases [BR:
hsa01001
]
Serine/threonine kinases: Other
NAK family [OT]
22848 (AAK1)
Membrane trafficking [BR:
hsa04131
]
Endocytosis
Clathrin-mediated endocytosis
Kinases
22848 (AAK1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
Kinase-like
Pkinase_fungal
ABC1
APH
Haspin_kinase
Motif
Other DBs
NCBI-GeneID:
22848
NCBI-ProteinID:
NP_055726
OMIM:
616405
HGNC:
19679
Ensembl:
ENSG00000115977
UniProt:
Q2M2I8
Structure
PDB
PDBj
LinkDB
All DBs
Position
2:complement(69457997..69643739)
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AA seq
961 aa
AA seq
DB search
MKKFFDSRREQGGSGLGSGSSGGGGSTSGLGSGYIGRVFGIGRQQVTVDEVLAEGGFAIV
FLVRTSNGMKCALKRMFVNNEHDLQVCKREIQIMRDLSGHKNIVGYIDSSINNVSSGDVW
EVLILMDFCRGGQVVNLMNQRLQTGFTENEVLQIFCDTCEAVARLHQCKTPIIHRDLKVE
NILLHDRGHYVLCDFGSATNKFQNPQTEGVNAVEDEIKKYTTLSYRAPEMVNLYSGKIIT
TKADIWALGCLLYKLCYFTLPFGESQVAICDGNFTIPDNSRYSQDMHCLIRYMLEPDPDK
RPDIYQVSYFSFKLLKKECPIPNVQNSPIPAKLPEPVKASEAAAKKTQPKARLTDPIPTT
ETSIAPRQRPKAGQTQPNPGILPIQPALTPRKRATVQPPPQAAGSSNQPGLLASVPQPKP
QAPPSQPLPQTQAKQPQAPPTPQQTPSTQAQGLPAQAQATPQHQQQLFLKQQQQQQQPPP
AQQQPAGTFYQQQQAQTQQFQAVHPATQKPAIAQFPVVSQGGSQQQLMQNFYQQQQQQQQ
QQQQQQLATALHQQQLMTQQAALQQKPTMAAGQQPQPQPAAAPQPAPAQEPAIQAPVRQQ
PKVQTTPPPAVQGQKVGSLTPPSSPKTQRAGHRRILSDVTHSAVFGVPASKSTQLLQAAA
AEASLNKSKSATTTPSGSPRTSQQNVYNPSEGSTWNPFDDDNFSKLTAEELLNKDFAKLG
EGKHPEKLGGSAESLIPGFQSTQGDAFATTSFSAGTAEKRKGGQTVDSGLPLLSVSDPFI
PLQVPDAPEKLIEGLKSPDTSLLLPDLLPMTDPFGSTSDAVIEKADVAVESLIPGLEPPV
PQRLPSQTESVTSNRTDSLTGEDSLLDCSLLSNPTTDLLEEFAPTAISAPVHKAAEDSNL
ISGFDVPEGSDKVAEDEFDPIPVLITKNPQGGHSRNSSGSSESSLPNLARSLLLVDQLID
L
NT seq
2886 nt
NT seq
+upstream
nt +downstream
nt
atgaagaagtttttcgactcccggcgagagcagggcggctctggcctgggctccggctcc
agcggaggagggggcagcacctcgggcctgggcagtggctacatcggaagagtcttcggc
atcgggcgacagcaggtcacagtggacgaggtgttggcggaaggtggatttgctattgta
tttctggtgaggacaagcaatgggatgaaatgtgccttgaaacgcatgtttgtcaacaat
gagcatgatctccaggtgtgcaagagagaaatccagataatgagggatctttcagggcac
aagaatattgtgggttacattgattctagtatcaacaacgtgagtagcggtgatgtatgg
gaagtgctcattctgatggacttttgtagaggtggccaggtggtaaacctgatgaaccag
cgcctgcaaacaggctttacagagaatgaagtgctccagatattttgtgatacctgtgaa
gctgttgcccgcctgcatcagtgcaaaactcctattatccaccgggacctgaaggttgaa
aacatcctcttgcatgaccgaggccactatgtcctgtgtgactttggaagcgccaccaac
aaattccagaatccacaaactgagggagtcaatgcagtagaagatgagattaagaaatac
acaacgctgtcctatcgagcaccagaaatggtcaacctgtacagtggcaaaatcatcact
acgaaggcagacatttgggctcttggatgtttgttgtataaattatgctacttcactttg
ccatttggggaaagtcaggtggcaatttgtgatggaaacttcacaattcctgataattct
cgatattctcaagacatgcactgcctaattaggtatatgttggaaccagaccctgacaaa
aggccggatatttaccaggtgtcctacttctcatttaagctactcaagaaagagtgccca
attccaaatgtacagaactctcccattcctgcaaagcttcctgaaccagtgaaagccagt
gaggcagctgcaaaaaagacccagccaaaggccagactgacagatcccattcccaccaca
gagacttcaattgcaccccgccagaggcctaaagctgggcagactcagccgaacccagga
atccttcccatccagccagcgctgacaccccggaagagggccactgttcagcccccacct
caggctgcaggatccagcaatcagcctggccttttagccagtgttccccaaccaaaaccc
caagccccacccagccagcctctgccgcaaactcaggccaagcagccacaggctcctccc
actccacagcagacgccttctactcaggcccagggtctgcccgctcaggcccaggccaca
ccccagcaccagcagcaactcttcctcaagcagcaacagcagcagcaacagccaccgcca
gcacagcagcagccggcaggcacgttttaccagcagcagcaggcccagactcagcagttt
caggcagtacatccagcaacccagaaaccagcaattgctcagttccctgtggtgtcccaa
ggaggctctcaacagcagctaatgcagaatttctaccagcagcagcagcagcagcaacaa
caacagcaacagcaacagctggccacagccctgcatcaacaacagctgatgactcagcag
gctgccttgcagcaaaagcccactatggcagcaggacagcagccccagccacagccagct
gcagccccacagccagcccctgcccaggagccagcgattcaagccccagtaagacaacag
ccaaaggttcagacaaccccacctcctgccgtccaggggcagaaagttggatctctcact
ccaccctcatcccccaaaacccaacgtgctgggcacaggcgtattctcagtgacgtaacc
cacagtgcagtctttggggtccctgccagcaaatcaacccagctgctccaggcagctgca
gctgaggccagtctcaataagtccaagtctgcaaccaccactccatcaggctctcctcgg
acctctcaacaaaacgtttataatccttcagaagggtctacgtggaatccctttgatgac
gataatttctccaaactcacagctgaagaactgctaaacaaggactttgccaagcttggg
gaaggcaaacatcccgagaagcttggaggctcagctgagagtttgatcccaggctttcaa
tcaacccaaggtgatgcttttgctacgacctcattttctgctggaactgctgaaaaaagg
aagggtgggcagactgtggactctggcctcccgcttctaagcgtgtctgatcctttcatt
cctcttcaagtacctgatgcaccagaaaaactaattgagggactcaaatctcctgacact
tctcttctgctccctgacctcttgcctatgacagatccttttggtagcacttctgatgct
gtaattgaaaaagctgatgttgctgttgagagtctcataccaggactggagcccccagtt
ccccagcgcctcccatctcagacggaatctgtgacctcgaatcgcacagattctctcacc
ggggaagattccctgcttgattgctctctgctctctaaccctactactgaccttctggaa
gagtttgcccccacagcaatctctgctccagtccataaagctgcagaagatagtaatctc
atctcaggttttgatgtccctgagggctcggacaaggtggctgaagatgagtttgaccct
attcctgtattgataaccaaaaacccacaaggtgggcactctagaaacagcagtgggagc
tctgagtccagtcttcccaacctagccaggtctttactgctggtggatcagctcatagac
ctgtag
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integrated database retrieval system
