| Entry |
|
|---|
| Name |
Milsaperidone (USAN) |
|---|
| Formula |
C24H29FN2O4
|
|---|
| Exact mass |
428.2111
|
|---|
| Mol weight |
428.50
|
|---|
| Structure |
|
|---|
| Class |
Neuropsychiatric agent
DG01478 Dopamine antagonist
DG01474 Dopamine D2-receptor antagonist
DG03005 Serotonin-dopamine antagonist (SDA)
|
|---|
| Efficacy |
Antipsychotic |
|---|
| Comment |
Risperidone derivative
Treatment of schizophrenia, bipolar disorder, and major depressive disorder
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Brite |
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01478 Dopamine antagonist
DG01474 Dopamine D2-receptor antagonist
D13099 Milsaperidone
DG03005 Serotonin-dopamine antagonist (SDA)
D13099 Milsaperidone
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Dopamine
DRD2
D13099 Milsaperidone (USAN)
Serotonin
HTR2
D13099 Milsaperidone (USAN)
|
|---|
| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 31
1 C1y C 14.9821 -15.2621
2 C1x C 14.9821 -13.8619
3 C1x C 16.2422 -15.9622
4 C1x C 16.2422 -13.1618
5 C1x C 17.4324 -15.2621
6 N1y N 17.4324 -13.8619
7 C1b C 18.6926 -13.1618
8 C1b C 19.8827 -13.8619
9 C8y C 13.7919 -15.9622
10 N5x N 12.6717 -15.1221
11 O2x O 11.5516 -15.9622
12 C8y C 11.9716 -17.2924
13 C8y C 13.3718 -17.2924
14 C8x C 11.2715 -18.4825
15 C8y C 11.9716 -19.7427
16 C8x C 13.3718 -19.7427
17 C8x C 14.0719 -18.5525
18 X F 11.2715 -20.9329
19 C1b C 21.0996 -13.1725
20 O2a O 22.2788 -13.8663
21 C8y C 23.4852 -13.1827
22 C8y C 24.7072 -13.9020
23 C8x C 25.9255 -13.2122
24 C8y C 25.8673 -11.8123
25 C8x C 24.7853 -11.0930
26 C8x C 23.4971 -11.7827
27 O2a O 24.6951 -15.3299
28 C1c C 27.1039 -11.1155
29 C1a C 28.3049 -11.8258
30 O1a O 27.1183 -9.7303
31 C1a C 23.4881 -16.0133
BOND 34
1 1 2 1
2 1 3 1
3 2 4 1
4 3 5 1
5 4 6 1
6 6 7 1
7 7 8 1
8 5 6 1
9 1 9 1
10 9 10 2
11 10 11 1
12 11 12 1
13 12 13 2
14 9 13 1
15 12 14 1
16 14 15 2
17 15 16 1
18 16 17 2
19 17 13 1
20 15 18 1
21 8 19 1
22 19 20 1
23 20 21 1
24 21 22 2
25 22 23 1
26 23 24 2
27 24 25 1
28 25 26 2
29 21 26 1
30 22 27 1
31 24 28 1
32 28 29 1
33 28 30 1 #Up
34 27 31 1
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