| Entry |
|
|---|
| Name |
Repibresib (USAN) |
|---|
| Formula |
C20H16N2O3
|
|---|
| Exact mass |
332.1161
|
|---|
| Mol weight |
332.35
|
|---|
| Structure |
|
|---|
| Efficacy |
Antivitiligo, BET inhibitor |
|---|
| Comment |
Treatment of vitiligo
|
|---|
| Target |
|
|---|
| Brite |
Target-based classification of drugs [BR:br08310]
Protein kinases
Serine/threonine kinases
Other
BRD2
D13101 Repibresib (USAN)
BRD3
D13101 Repibresib (USAN)
BRD4
D13101 Repibresib (USAN)
BRDT
D13101 Repibresib (USAN)
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 25
1 C8x C 15.5400 -12.4600
2 C8x C 15.5400 -13.8600
3 C8x C 16.7300 -14.5600
4 C8y C 17.9900 -13.8600
5 C8x C 17.9900 -12.4600
6 C8x C 16.7300 -11.7600
7 O2a O 19.1800 -14.5600
8 C8y C 20.4400 -13.9300
9 C8y C 21.6300 -14.5600
10 C8x C 22.8200 -13.8600
11 C8x C 22.8200 -12.4600
12 C8x C 21.6300 -11.7600
13 C8y C 20.4400 -12.4600
14 C8y C 21.6300 -15.9600
15 C8x C 20.3700 -16.6600
16 N4y N 20.3700 -18.1300
17 C8y C 21.5600 -18.8300
18 C8y C 22.8200 -18.0600
19 C8y C 22.8200 -16.6600
20 N4x N 24.1500 -18.5500
21 C8x C 24.9900 -17.3600
22 C8x C 24.1500 -16.2400
23 C1a C 19.1800 -18.7600
24 O5x O 21.5600 -20.1600
25 O1a O 19.2500 -11.7600
BOND 28
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 4 7 1
8 7 8 1
9 8 9 2
10 9 10 1
11 10 11 2
12 11 12 1
13 12 13 2
14 8 13 1
15 9 14 1
16 14 15 2
17 15 16 1
18 16 17 1
19 17 18 1
20 18 19 2
21 14 19 1
22 18 20 1
23 20 21 1
24 21 22 2
25 19 22 1
26 16 23 1
27 17 24 2
28 13 25 1
|
|---|
