Homo sapiens (human): 6046
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Entry
6046 CDS
T01001
Symbol
BRD2, BRD2-IT1, D6S113E, FSH, FSHRG1, FSRG1, NAT, O27.1.1, RING3, RNF3
Name
(RefSeq) bromodomain containing 2
KO
K08871
bromodomain-containing protein 2
Organism
hsa
Homo sapiens (human)
Drug target
Apabetalone:
D11131
Birabresib:
D10911
Pelabresib:
D12266
Repibresib:
D13101
Trotabresib:
D12006
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
hsa01001
]
6046 (BRD2)
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
hsa03036
]
6046 (BRD2)
Protein kinases [BR:
hsa01001
]
Serine/threonine kinases: Other
BRD family [OT]
6046 (BRD2)
Chromosome and associated proteins [BR:
hsa03036
]
Eukaryotic type
Chromatin remodeling factors
Other chromatin remodeling factors
6046 (BRD2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Bromodomain
BET
Sigma70_ner
DUF6779
Motif
Other DBs
NCBI-GeneID:
6046
NCBI-ProteinID:
NP_001106653
OMIM:
601540
HGNC:
1103
Ensembl:
ENSG00000204256
UniProt:
P25440
Structure
PDB
PDBj
LinkDB
All DBs
Position
6:32968594..32981505
Genome browser
AA seq
801 aa
AA seq
DB search
MLQNVTPHNKLPGEGNAGLLGLGPEAAAPGKRIRKPSLLYEGFESPTMASVPALQLTPAN
PPPPEVSNPKKPGRVTNQLQYLHKVVMKALWKHQFAWPFRQPVDAVKLGLPDYHKIIKQP
MDMGTIKRRLENNYYWAASECMQDFNTMFTNCYIYNKPTDDIVLMAQTLEKIFLQKVASM
PQEEQELVVTIPKNSHKKGAKLAALQGSVTSAHQVPAVSSVSHTALYTPPPEIPTTVLNI
PHPSVISSPLLKSLHSAGPPLLAVTAAPPAQPLAKKKGVKRKADTTTPTPTAILAPGSPA
SPPGSLEPKAARLPPMRRESGRPIKPPRKDLPDSQQQHQSSKKGKLSEQLKHCNGILKEL
LSKKHAAYAWPFYKPVDASALGLHDYHDIIKHPMDLSTVKRKMENRDYRDAQEFAADVRL
MFSNCYKYNPPDHDVVAMARKLQDVFEFRYAKMPDEPLEPGPLPVSTAMPPGLAKSSSES
SSEESSSESSSEEEEEEDEEDEEEEESESSDSEEERAHRLAELQEQLRAVHEQLAALSQG
PISKPKRKREKKEKKKKRKAEKHRGRAGADEDDKGPRAPRPPQPKKSKKASGSGGGSAAL
GPSGFGPSGGSGTKLPKKATKTAPPALPTGYDSEEEEESRPMSYDEKRQLSLDINKLPGE
KLGRVVHIIQAREPSLRDSNPEEIEIDFETLKPSTLRELERYVLSCLRKKPRKPYTIKKP
VGKTKEELALEKKRELEKRLQDVSGQLNSTKKPPKKANEKTESSSAQQVAVSRLSASSSS
SDSSSSSSSSSSSDTSDSDSG
NT seq
2406 nt
NT seq
+upstream
nt +downstream
nt
atgctgcaaaacgtgactccccacaataagctccctggggaagggaatgcagggttgctg
gggctgggcccagaagcagcagcaccagggaagaggattcgaaaaccctctctcttgtat
gagggctttgagagccccacaatggcttcggtgcctgctttgcaacttacccctgccaac
ccaccacccccggaggtgtccaatcccaaaaagccaggacgagttaccaaccagctgcaa
tacctacacaaggtagtgatgaaggctctgtggaaacatcagttcgcatggccattccgg
cagcctgtggatgctgtcaaactgggtctaccggattatcacaaaattataaaacagcct
atggacatgggtactattaagaggagacttgaaaacaattattattgggctgcttcagag
tgtatgcaagattttaataccatgttcaccaactgttacatttacaacaagcccactgat
gatattgtcctaatggcacaaacgctggaaaagatattcctacagaaggttgcatcaatg
ccacaagaagaacaagagctggtagtgaccatccctaagaacagccacaagaagggggcc
aagttggcagcgctccagggcagtgttaccagtgcccatcaggtgcctgccgtctcttct
gtgtcacacacagccctgtatactcctccacctgagatacctaccactgtcctcaacatt
ccccacccatcagtcatttcctctccacttctcaagtccttgcactctgctggacccccg
ctccttgctgttactgcagctcctccagcccagccccttgccaagaaaaaaggcgtaaag
cggaaagcagatactaccacccctacacctacagccatcttggctcctggttctccagct
agccctcctgggagtcttgagcctaaggcagcacggcttccccctatgcgtagagagagt
ggtcgccccatcaagcccccacgcaaagacttgcctgactctcagcaacaacaccagagc
tctaagaaaggaaagctttcagaacagttaaaacattgcaatggcattttgaaggagtta
ctctctaagaagcatgctgcctatgcttggcctttctataaaccagtggatgcttctgca
cttggcctgcatgactaccatgacatcattaagcaccccatggacctcagcactgtcaag
cggaagatggagaaccgtgattaccgggatgcacaggagtttgctgctgatgtacggctt
atgttctccaactgctataagtacaatcccccagatcacgatgttgtggcaatggcacga
aagctacaggatgtatttgagttccgttatgccaagatgccagatgaaccactagaacca
gggcctttaccagtctctactgccatgccccctggcttggccaaatcgtcttcagagtcc
tccagtgaggaaagtagcagtgagagctcctctgaggaagaggaggaggaagatgaggag
gacgaggaggaagaagagagtgaaagctcagactcagaggaagaaagggctcatcgctta
gcagaactacaggaacagcttcgggcagtacatgaacaactggctgctctgtcccagggt
ccaatatccaagcccaagaggaaaagagagaaaaaagagaaaaagaagaaacggaaggca
gagaagcatcgaggccgagctggggccgatgaagatgacaaggggcctagggcaccccgc
ccacctcaacctaagaagtccaagaaagcaagtggcagtgggggtggcagtgctgcttta
ggcccttctggctttggaccttctggaggaagtggcaccaagctccccaaaaaggccaca
aagacagccccacctgccctgcctacaggttatgattcagaggaggaggaagagagcagg
cccatgagttacgatgagaagcggcagctgagcctggacatcaacaaattacctggggag
aagctgggccgagttgtgcatataatccaagccagggagccctctttacgtgattcaaac
ccagaagagattgagattgattttgaaacactcaagccatccacacttagagagcttgag
cgctatgtcctttcctgcctacgtaagaaaccccggaagccctacaccattaagaagcct
gtgggaaagacaaaggaggaactggctttggagaaaaagcgggaattagaaaagcggtta
caagatgtcagcggacagctcaattctactaaaaagccccccaagaaagcgaatgagaaa
acagagtcatcctctgcacagcaagtagcagtgtcacgccttagcgcttccagctccagc
tcagattccagctcctcctcttcctcgtcgtcgtcttcagacaccagtgattcagactca
ggctaa
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