| Entry |
|
|---|
| Name |
Forvisirvat (USAN) |
|---|
| Formula |
C19H17ClN2O6
|
|---|
| Exact mass |
404.0775
|
|---|
| Mol weight |
404.80
|
|---|
| Structure |
|
|---|
| Efficacy |
Antidepressant, Sirtuin 6 activator |
|---|
| Comment |
Treatment of major depressive disorder
|
|---|
| Target |
|
|---|
| Pathway |
| hsa00760 | Nicotinate and nicotinamide metabolism |
|
|---|
| Brite |
Target-based classification of drugs [BR:br08310]
Enzymes
Transferases (EC2)
Acyltransferases
SIRT6
D13109 Forvisirvat (USAN)
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 28
1 C8y C 18.2302 -15.1428
2 C8y C 18.2302 -16.5449
3 C8y C 19.4444 -17.2459
4 C8x C 20.6587 -16.5449
5 C8y C 20.6587 -15.1428
6 C8y C 19.4444 -14.4418
7 O2x O 16.8967 -14.7096
8 C1z C 16.0726 -15.8439
9 C5x C 16.8967 -16.9782
10 O5x O 16.4673 -18.2997
11 O2a O 19.4444 -18.6478
12 C1a C 18.2134 -19.3588
13 C8y C 21.8910 -14.4299
14 O2x O 23.2265 -14.8172
15 C8y C 24.0089 -13.6662
16 N5x N 23.1560 -12.5662
17 N5x N 21.8464 -13.0375
18 C1a C 25.3799 -13.6934
19 X Cl 19.4444 -13.0399
20 C2y C 15.4260 -14.6297
21 C2x C 14.0240 -14.6297
22 C5x C 13.3229 -15.8439
23 C1x C 14.0240 -17.0581
24 C1y C 15.4260 -17.0581
25 O5x O 11.9209 -15.8439
26 O2a O 16.1175 -13.4324
27 C1a C 17.5288 -13.4323
28 C1a C 14.7250 -18.2724
BOND 31
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 1 7 1
8 8 7 1 #Up
9 8 9 1
10 2 9 1
11 9 10 2
12 3 11 1
13 11 12 1
14 5 13 1
15 13 14 1
16 14 15 1
17 15 16 2
18 16 17 1
19 13 17 2
20 15 18 1
21 6 19 1
22 20 21 2
23 21 22 1
24 22 23 1
25 23 24 1
26 22 25 2
27 20 26 1
28 26 27 1
29 24 28 1 #Down
30 8 20 1
31 8 24 1
|
|---|
