KEGG   Homo sapiens (human): 51548
Entry
51548             CDS       T01001                                 
Symbol
SIRT6, SIR2L6, hSIRT6
Name
(RefSeq) sirtuin 6
  KO
K11416  NAD-dependent protein deacetylase sirtuin 6 [EC:2.3.1.286]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00760  Nicotinate and nicotinamide metabolism
hsa01100  Metabolic pathways
hsa04714  Thermogenesis
hsa05230  Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00760 Nicotinate and nicotinamide metabolism
    51548 (SIRT6)
 09150 Organismal Systems
  09159 Environmental adaptation
   04714 Thermogenesis
    51548 (SIRT6)
 09160 Human Diseases
  09161 Cancer: overview
   05230 Central carbon metabolism in cancer
    51548 (SIRT6)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:hsa03036]
    51548 (SIRT6)
Enzymes [BR:hsa01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.286  protein acetyllysine N-acetyltransferase
     51548 (SIRT6)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic type
  Histone modification proteins
   HDACs (histone deacetylases)
    SIRTs (sirtuins, class III HDACs)
     51548 (SIRT6)
SSDB
Motif
Pfam: SIR2 TPP_enzyme_M
Other DBs
NCBI-GeneID: 51548
NCBI-ProteinID: NP_057623
OMIM: 606211
HGNC: 14934
Ensembl: ENSG00000077463
UniProt: Q8N6T7
Structure
LinkDB
Position
19:complement(4174109..4182563)
AA seq 355 aa
MSVNYAAGLSPYADKGKCGLPEIFDPPEELERKVWELARLVWQSSSVVFHTGAGISTASG
IPDFRGPHGVWTMEERGLAPKFDTTFESARPTQTHMALVQLERVGLLRFLVSQNVDGLHV
RSGFPRDKLAELHGNMFVEECAKCKTQYVRDTVVGTMGLKATGRLCTVAKARGLRACRGE
LRDTILDWEDSLPDRDLALADEASRNADLSITLGTSLQIRPSGNLPLATKRRGGRLVIVN
LQPTKHDRHADLRIHGYVDEVMTRLMKHLGLEIPAWDGPRVLERALPPLPRPPTPKLEPK
EESPTRINGSIPAGPKQEPCAQHNGSEPASPKRERPTSPAPHRPPKRVKAKAVPS
NT seq 1068 nt   +upstreamnt  +downstreamnt
atgtcggtgaattacgcggcggggctgtcgccgtacgcggacaagggcaagtgcggcctc
ccggagatcttcgaccccccggaggagctggagcggaaggtgtgggaactggcgaggctg
gtctggcagtcttccagtgtggtgttccacacgggtgccggcatcagcactgcctctggc
atccccgacttcaggggtccccacggagtctggaccatggaggagcgaggtctggccccc
aagttcgacaccacctttgagagcgcgcggcccacgcagacccacatggcgctggtgcag
ctggagcgcgtgggcctcctccgcttcctggtcagccagaacgtggacgggctccatgtg
cgctcaggcttccccagggacaaactggcagagctccacgggaacatgtttgtggaagaa
tgtgccaagtgtaagacgcagtacgtccgagacacagtcgtgggcaccatgggcctgaag
gccacgggccggctctgcaccgtggctaaggcaagggggctgcgagcctgcaggggagag
ctgagggacaccatcctagactgggaggactccctgcccgaccgggacctggcactcgcc
gatgaggccagcaggaacgccgacctgtccatcacgctgggtacatcgctgcagatccgg
cccagcgggaacctgccgctggctaccaagcgccggggaggccgcctggtcatcgtcaac
ctgcagcccaccaagcacgaccgccatgctgacctccgcatccatggctacgttgacgag
gtcatgacccggctcatgaagcacctggggctggagatccccgcctgggacggcccccgt
gtgctggagagggcgctgccacccctgccccgcccgcccacccccaagctggagcccaag
gaggaatctcccacccggatcaacggctctatccccgccggccccaagcaggagccctgc
gcccagcacaacggctcagagcccgccagccccaaacgggagcggcccaccagccctgcc
ccccacagaccccccaaaagggtgaaggccaaggcggtccccagctga

DBGET integrated database retrieval system