KEGG   DRUG: Navepegritide
Entry
D13294                      Drug                                   
Name
Navepegritide (USAN/INN);
Yuviwel (TN)
Formula
C231H386N64O67S5. (C2H4O)4n
Structure
Sequence
LQEHPNARKY KGANKKGLSK GCFGLKLDRI GSMSGLGC
  Type
Peptide
Efficacy
Achondroplasia therapeutic agent
  Disease
Achondroplasia [DS:H01749]
  Type
Modified peptide
Comment
Treatment of achondroplasia and other skeletal disorders
modified c-Type natriuretic peptide (CNP): CNP fragment conjugated at Lys26 with linker
Target
NPR2 [HSA:4882] [KO:K12324]
  Pathway
hsa04022  cGMP-PKG signaling pathway
Brite
Target-based classification of drugs [BR:br08310]
 Protein kinases
  Serine/threonine kinases
   Other
    NPR2
     D13294  Navepegritide (USAN/INN)
New drug approvals in the USA [br08319.html]
 New molecular entities and new therapeutic biological products
  D13294
New drug approvals in the USA, Europe and Japan [br08328.html]
 Approval dates by FDA, EMA and PMDA
  D13294
Other DBs
CAS: 2413551-27-4
PubChem: 528318784
LinkDB

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