Entry
Name
Composition
(Gal)2 (GalNAc)1 (Glc)1 (Neu5Ac)2 (Cer)1
Mass
1272.1 (Cer)
Structure
KCF file KCaM SNFG
Reaction
Pathway
map00604 Glycosphingolipid biosynthesis - ganglio series
Enzyme
Orthology
K00785 N-acetyllactosaminide alpha-2,3-sialyltransferase [EC:2.4.3.6 ]
K03373 N-acetylgalactosaminide alpha-2,6-sialyltransferase (sialyltransferase 7C) [EC:2.4.3.7 ]
K03374 N-acetylgalactosaminide alpha-2,6-sialyltransferase (sialyltransferase 7D) [EC:2.4.3.7 ]
K03375 N-acetylgalactosaminide alpha-2,6-sialyltransferase (sialyltransferase 7E) [EC:2.4.3.-]
K03376 N-acetylgalactosaminide alpha-2,6-sialyltransferase (sialyltransferase 7F) [EC:2.4.3.-]
Brite
Lipids [BR:br08002 ]
SP Sphingolipids
SP06 Acidic glycosphingolipids
SP0601 Gangliosides
G00127 Neu5Ac-alpha2->3Gal-beta1->3(Neu5Ac-alpha2->6)GalNAc-beta1->4Gal-beta1->4Glc-beta1->1'Cer
Cancer-associated carbohydrates [br08441.html ]
G00127
BRITE hierarchy
Reference
Authors
Saito S, Levery SB, Salyan ME, Goldberg RI, Hakomori S.
Title
Common tetrasaccharide epitope NeuAc alpha 2-->3Gal beta 1-->3(Neu-Ac alpha 2-->6)GalNAc, presented by different carrier glycosylceramides or O-linked peptides, is recognized by different antibodies and ligands having distinct specificities.
Journal
J Biol Chem 269:5644-52 (1994)
Other DBs
LinkDB
All DBs
KCF data
Show NODE 7
1 Cer 17 0
2 Glc 11 0
3 Gal 5 0
4 GalNAc -3 0
5 Gal -10 -4
6 Neu5Ac -11 4
7 Neu5Ac -18 -4
EDGE 6
1 2:b1 1:1
2 3:b1 2:4
3 4:b1 3:4
4 5:b1 4:3
5 6:a2 4:6
6 7:a2 5:3