KEGG   GLYCAN: G00127
Entry
G00127                      Glycan                                 
Name
GD1a
Composition
(Gal)2 (GalNAc)1 (Glc)1 (Neu5Ac)2 (Cer)1
Mass
1272.1 (Cer)
Structure
Reaction
R05959
Pathway
map00604  Glycosphingolipid biosynthesis - ganglio series
map01100  Metabolic pathways
Enzyme
2.4.3.7
Orthology
K00785  N-acetyllactosaminide alpha-2,3-sialyltransferase [EC:2.4.3.6]
K03373  N-acetylgalactosaminide alpha-2,6-sialyltransferase (sialyltransferase 7C) [EC:2.4.3.7]
K03374  N-acetylgalactosaminide alpha-2,6-sialyltransferase (sialyltransferase 7D) [EC:2.4.3.7]
K03375  N-acetylgalactosaminide alpha-2,6-sialyltransferase (sialyltransferase 7E) [EC:2.4.3.-]
K03376  N-acetylgalactosaminide alpha-2,6-sialyltransferase (sialyltransferase 7F) [EC:2.4.3.-]
Brite
Lipids [BR:br08002]
 SP  Sphingolipids
  SP06 Acidic glycosphingolipids
   SP0601 Gangliosides
    G00127  Neu5Ac-alpha2->3Gal-beta1->3(Neu5Ac-alpha2->6)GalNAc-beta1->4Gal-beta1->4Glc-beta1->1'Cer
Cancer-associated carbohydrates [br08441.html]
 G00127
Reference
1  [PMID:7509790]
  Authors
Saito S, Levery SB, Salyan ME, Goldberg RI, Hakomori S.
  Title
Common tetrasaccharide epitope NeuAc alpha 2-->3Gal beta 1-->3(Neu-Ac alpha 2-->6)GalNAc, presented by different carrier glycosylceramides or O-linked peptides, is recognized by different antibodies and ligands having distinct specificities.
  Journal
J Biol Chem 269:5644-52 (1994)
Other DBs
LinkDB
KCF data

NODE        7
            1   Cer        17     0
            2   Glc        11     0
            3   Gal         5     0
            4   GalNAc     -3     0
            5   Gal       -10    -4
            6   Neu5Ac    -11     4
            7   Neu5Ac    -18    -4
EDGE        6
            1     2:b1    1:1  
            2     3:b1    2:4  
            3     4:b1    3:4  
            4     5:b1    4:3  
            5     6:a2    4:6  
            6     7:a2    5:3

DBGET integrated database retrieval system