KEGG   GLYCAN: G00181
Entry
G00181                      Glycan                                 
Name
Disialosylglobopentaosylceramide;
Disialosyl Gb5;
V3NeuAcIV6NeuAc-Gb5Cer;
Disialosylgalactosylgloboside
Composition
(Gal)3 (GalNAc)1 (Glc)1 (Neu5Ac)2 (Cer)1
Mass
1434.3 (Cer)
Structure
Pathway
map00603  Glycosphingolipid biosynthesis - globo and isoglobo series
Brite
Lipids [BR:br08002]
 SP  Sphingolipids
  SP06 Acidic glycosphingolipids
   SP0601 Gangliosides
    G00181  Neu5Ac-alpha2->3Gal-beta1->3(Neu5Ac-alpha2->6)GalNAc-beta1->3Gal-alpha1->4Gal-beta1->4Glc-beta1->1'Cer
Cancer-associated carbohydrates [br08441.html]
 Glycosphingolipid
  G00181
Reference
1  [PMID:7509790]
  Authors
Saito S, Levery SB, Salyan ME, Goldberg RI, Hakomori S.
  Title
Common tetrasaccharide epitope NeuAc alpha 2-->3Gal beta 1-->3(Neu-Ac alpha 2-->6)GalNAc, presented by different carrier glycosylceramides or O-linked peptides, is recognized by different antibodies and ligands having distinct specificities.
  Journal
J Biol Chem 269:5644-52 (1994)
Reference
2  [PMID:11278988]
  Authors
Ito A, Levery SB, Saito S, Satoh M, Hakomori S.
  Title
A novel ganglioside isolated from renal cell carcinoma.
  Journal
J Biol Chem 276:16695-703 (2001)
DOI:10.1074/jbc.M011791200
Other DBs
CCSD: 
GlyTouCan: G97932OH
LIPIDMAPS: LMSP0601AC00
JCGGDB: JCGG-STR003128
GlycoEpitope: EP0098
LinkDB
KCF data

NODE        8
            1   Cer      29.4     0
            2   Glc      21.4     0
            3   Gal      13.4     0
            4   Gal       5.4     0
            5   GalNAc   -3.6     0
            6   Gal     -12.6    -4
            7   Neu5Ac  -13.6     4
            8   Neu5Ac  -21.6    -4
EDGE        7
            1     2:b1    1:1  
            2     3:b1    2:4  
            3     4:a1    3:4  
            4     5:b1    4:3  
            5     6:b1    5:3  
            6     7:a2    5:6  
            7     8:a2    6:3

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