Human hookworm disease is a chronic intestinal nematode infection most commonly caused by Ancylostoma duodenale and Necator americanus, which are transmitted via skin contact with fecally contaminated soil. The major clinical features are anemia and malnutrition. Humans may also be incidentally infected by the zoonotic hookworms, the most common being A. braziliense and A. caninum, which can cause cutaneous larva migrans.
