KEGG   DISEASE: Familial dementia
Entry
H01184                      Disease                                
Name
Familial dementia
Description
Familial British dementia (FBD) and familial Danish dementia (FDD) are two autosomal dominant neurodegenerative diseases caused by mutations in the BRI/ ITM2B gene. Familial dementia is characterized by widespread cerebral amyloid angiopathy, parenchymal amyloid deposition, and neurofibrillary tangles.
Category
Neurodegenerative disease
Brite
Human diseases in ICD-11 classification [BR:br08403]
 08 Diseases of the nervous system
  Cerebrovascular diseases
   8B22  Certain specified cerebrovascular diseases
    H01184  Familial dementia
Gene
ITM2B [HSA:9445] [KO:K18264]
Other DBs
ICD-11: 8B22.3
MeSH: D003704
OMIM: 176500 117300
Reference
PMID:19779737
  Authors
Garringer HJ, Murrell J, D'Adamio L, Ghetti B, Vidal R
  Title
Modeling familial British and Danish dementia.
  Journal
Brain Struct Funct 214:235-44 (2010)
DOI:10.1007/s00429-009-0221-9
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