| 概要 |
Acute febrile neutrophilic dermatosis (AFND), also referred to as pyrin-associated autoinflammatory disease (PAAND), is an autosomal dominant autoinflammatory disorder characterized by fever and arthritis. Pyrin encoded by MEFV gene is a protein involved as a suppressor of inflammasome and mutations in the MEFV gene have been linked to AFND.
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| 著者 |
Otsuka M, Koga T, Sumiyoshi R, Koike Y, Furukawa K, Okamoto M, Endo Y, Tsuji S, Takatani A, Shimizu T, Igawa T, Kawashiri SY, Iwamoto N, Ichinose K, Tamai M, Nakamura H, Origuchi T, Daisuke N, Kawakami A |
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| 著者 |
Masumoto J, Zhou W, Morikawa S, Hosokawa S, Taguchi H, Yamamoto T, Kurata M, Kaneko N |
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