Becker nevus syndrome (BNS) is a epidermal nevus syndrome characterized by the presence of a particular type of organoid epithelial nevus showing circumscribed hyperpigmentation with hypertrichosis, and developmental abnormalities of different organ systems. It has been identified that mutations in ACTB, encoding for beta-actin, are associated with BNS.
Category
Congenital malformation
Brite
Human diseases in ICD-11 classification [BR:br08403]
20 Developmental anomalies
Structural developmental anomalies primarily affecting one body system
Structural developmental anomalies of the skin
Developmental hamartomata of the epidermis and epidermal appendages
LC02 Complex epidermal hamartoma
H02716 Becker nevus syndrome
Pathway-based classification of diseases [BR:br08402]
Cellular process
nt06539 Cytoskeleton in muscle cells
H02716 Becker nevus syndrome
