Auroneurodental syndrome (ANDS) is a novel genetic disorder characterized by progressive high-frequency sensorineural hearing loss, craniofacial dysmorphisms, developmental delay and mild proximal and axial muscle weakness. It has been reported mutations in NAA80 cause this syndrome. NAA80 is the N-terminal acetyltransferase expressed in the animal kingdom. NAA80 was recently found to specifically N-terminally acetylate actin.
