| 概要 |
Yellow nail syndrome (YNS) is a rare disorder characterized by a triad of nail abnormalities, chronic respiratory disease, and primary lymphoedema. Because most patients lack a positive family history, and given the typically late onset of the disease as well as the potential recovery of nail changes, YNS is generally not considered to be a primarily genetic disease. However, recent studies have suggested that defects in planar cell polarity (PCP) organization may play an important role in the pathogenesis of YNS.
|
|---|
| 著者 |
Kurolap A, Chai Gadot C, Eshach Adiv O, Hershkovitz T, Avitan-Hersh E, Martin L, Humeau H, Schatz UA, Westphal DS, Lobmaier S, Sofrin-Drucker E, Stafler P, Bugis J, Chermesh I, Hardak E, Geva P, Zohar Y, Hershkovitz D, Mory A, Chatterji S, Greenberger S, Shteinberg M, Baris Feldman H |
|---|
