KEGG   ORTHOLOGY: K00300
Entry
K00300                      KO                                     
Symbol
mtdA
Name
methylenetetrahydrofolate/methylenetetrahydromethanopterin dehydrogenase (NADP+) [EC:1.5.1.5 1.5.1.-]
Pathway
map00670  One carbon pool by folate
map00680  Methane metabolism
map01100  Metabolic pathways
map01120  Microbial metabolism in diverse environments
map01240  Biosynthesis of cofactors
Module
M00140  C1-unit interconversion, prokaryotes
Reaction
R01220  5,10-methylenetetrahydrofolate:NADP+ oxidoreductase
R08059  
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09102 Energy metabolism
   00680 Methane metabolism
    K00300  mtdA; methylenetetrahydrofolate/methylenetetrahydromethanopterin dehydrogenase (NADP+)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    K00300  mtdA; methylenetetrahydrofolate/methylenetetrahydromethanopterin dehydrogenase (NADP+)
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.5  methylenetetrahydrofolate dehydrogenase (NADP+)
     K00300  mtdA; methylenetetrahydrofolate/methylenetetrahydromethanopterin dehydrogenase (NADP+)
Other DBs
GO: 0004488
Genes
MCA: MCA0508
METU: GNH96_13770
MMEO: OOT43_08830
MEEF: JWZ97_02310
MMT: Metme_2715
MDN: JT25_018050
MDH: AYM39_08875
MKO: MKLM6_1850
METL: U737_08940
MPAD: KEF85_02440
MELL: IVG45_03000
MRP: NM686_010320
MMOT: QZJ86_11930
MEEP: JWZ98_08205
MEEC: PL263_03880
MEUP: QC632_10020
MAH: MEALZ_3221(mtdA)
MBUR: EQU24_04570
MPSY: CEK71_10730
MMAI: sS8_1023
MSZE: MSZNOR_0597(mtdA)
MMOB: F6R98_09875
MEIN: methR_P0717
MOZ: MoryE10_26120(mtdA)
MISZ: MishRS11D_20060(mtdA)
MESL: KKZ03_00280
MECH: Q9L42_001145
MEIY: MIN45_P1256
MCAU: MIT9_P1269
MEJ: Q7A_616
MEC: Q7C_2202
MPIN: LGT42_000030
MMAF: GCM100_12060(mtdA)
MTHA: VSX76_03940
NHL: Nhal_3872
NWR: E3U44_04695
MPT: Mpe_A3259
METP: C1M51_05920
METR: BSY238_260(mtdA)
FMY: HO273_02495
MEA: Mex_1p1728(mtdA)
MDI: METDI2480(mtdA)
MEX: Mext_1797
MCH: Mchl_2133
MPO: Mpop_1749
MZA: B2G69_16645
MRD: Mrad2831_3668
MET: M446_6554
MNO: Mnod_7114
MOR: MOC_4192
META: Y590_08590
MAQU: Maq22A_c19275(mtdA)
MPHY: MCBMB27_03150
MEE: DA075_26530
METD: C0214_10355
METX: A3862_13145
METS: DK389_15335
METI: DK427_15530
MMES: MMSR116_21290
MTEA: DK419_14265
MIND: mvi_28910(mtdA)
MOG: MMB17_01125
MTAD: M6G65_20445
MLG: CWB41_15800
MEDK: QEV83_17980
MCG: GL4_3376
METG: HT051_02820
MSC: BN69_1176
MBRY: B1812_17515
MROS: EHO51_12210
MHEY: H2LOC_011830
MPAR: F7D14_09150
MIWA: SS37A_07140(mtdA)
MESZ: LNB28_12730
MTW: CQW49_12210
MECQ: MSC49_04660(mtdA)
CMET: K6K41_15055
GBE: GbCGDNIH1_0050
GBH: GbCGDNIH2_0050
GBC: GbCGDNIH3_0050
GBS: GbCGDNIH4_0050
CMIC: caldi_15590(mtdA)
FWA: DCMF_03880
HAS: Halsa_0940
RBA: RB10295(mtdA)
PSL: Psta_2659
PIR: VN12_15785(mtdA)
RUL: UC8_11070(mtdA)
RML: FF011L_55010(mtdA)
MFF: MFFC18_24480(mtdA)
ROL: CA51_24720(mtdA)
RUV: EC9_20900(mtdA)
RCF: Poly24_24120(mtdA)
AHEL: Q31a_40210(mtdA)
LCRE: Pla8534_42860(mtdA)
AAGG: ETAA8_15630(mtdA)
BVO: Pan97_44440(mtdA)
BREM: PSR63_16255
RLC: K227x_52060(mtdA)
SMAM: Mal15_51970(mtdA)
SNEP: Enr13x_11870(mtdA)
LPAV: PLANPX_0555
LLH: I41_06160(mtdA)
AMUC: Pan181_45490(mtdA)
PND: Pla175_50930(mtdA)
AMOB: HG15A2_07270(mtdA)
BGOK: Pr1d_52170(mtdA)
PLM: Plim_3754
PEH: Spb1_04100(mtdA)
PBS: Plabr_0088
PLS: VT03_31910(mtdA)
PLH: VT85_19965(mtdA)
FMR: Fuma_03860(mtdA)
GMR: GmarT_10990(mtdA)
GIM: F1728_09270
GPN: Pan110_10790(mtdA)
GFM: Enr17x_11800(mtdA)
GAZ: Pan241w_11950(mtdA)
GAW: V144x_46830(mtdA)
GAX: Pan161_24110(mtdA)
MRI: Mal4_08500(mtdA)
SDYN: Mal52_22850(mtdA)
PLON: Pla110_21490(mtdA)
ACAF: CA12_34250(mtdA)
SVP: Pan189_25060(mtdA)
TPOL: Mal48_43430(mtdA)
CHYA: V22_25580(mtdA)
CCOS: Pan44_04630(mtdA)
PVAR: SH412_003218
CCOP: Mal65_19270(mtdA)
GES: VT84_01765(mtdA)
GOG: C1280_25115
GMS: SOIL9_75900
TIM: GMBLW1_35630
LRS: PX52LOC_00082
FTJ: FTUN_3065
ULI: ETAA1_52350(mtdA)
TSPH: KIH39_14270
IPA: Isop_1012
SACI: Sinac_4955
PBOR: BSF38_04914(mtdA)
AGV: OJF2_60600(mtdA)
TPLA: ElP_20280(mtdA)
AMO: Anamo_1147
ARAM: KAR29_10190
 » show all
Reference
PMID:8144463
  Authors
Chistoserdova LV, Lidstrom ME
  Title
Genetics of the serine cycle in Methylobacterium extorquens AM1: identification of sgaA and mtdA and sequences of sgaA, hprA, and mtdA.
  Journal
J Bacteriol 176:1957-68 (1994)
DOI:10.1128/JB.176.7.1957-1968.1994
  Sequence
[mea:Mex_1p1728]
Reference
PMID:9765566
  Authors
Vorholt JA, Chistoserdova L, Lidstrom ME, Thauer RK
  Title
The NADP-dependent methylene tetrahydromethanopterin dehydrogenase in Methylobacterium extorquens AM1.
  Journal
J Bacteriol 180:5351-6 (1998)
DOI:10.1128/JB.180.20.5351-5356.1998
  Sequence
[mea:Mex_1p1728]
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