KEGG ORTHOLOGY: K00893

ORTHOLOGY: K00893

Entry

K00893                      KO

Symbol

DCK

Name

deoxycitidine/deoxyadenosine/deoxyguanosine kinase [EC:2.7.1.74 2.7.1.76 2.7.1.113]

Pathway

map00230

Purine metabolism

map00240

Pyrimidine metabolism

map01100

Metabolic pathways

map01232

Nucleotide metabolism

Reaction

R01666

ATP:deoxycitidine 5'-phosphotransferase

R01967

ATP:deoxyguanosine 5'-phosphotransferase

R02089

ATP:deoxyadenosine 5'-phosphotransferase

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    K00893  DCK; deoxycitidine/deoxyadenosine/deoxyguanosine kinase
   00240 Pyrimidine metabolism
    K00893  DCK; deoxycitidine/deoxyadenosine/deoxyguanosine kinase
Enzymes [BR:ko01000]
2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.74  deoxycytidine kinase
     K00893  DCK; deoxycitidine/deoxyadenosine/deoxyguanosine kinase
    2.7.1.76  2'-deoxyadenosine kinase
     K00893  DCK; deoxycitidine/deoxyadenosine/deoxyguanosine kinase
    2.7.1.113  deoxyguanosine kinase
     K00893  DCK; deoxycitidine/deoxyadenosine/deoxyguanosine kinase

Other DBs

GO:	0004137 0004136 0004138

Genes

HSA:

1633(DCK)

PTR:	104008182 461273(DCK)

PPS:	100990892(DCK) 117974604

GGO:	101153698(DCK) 109028486

PON:	100459989(DCK)

PPYG:

129035365(DCK)

NLE:	100580396(DCK)

HMH:	116467104(DCK)

SSYN:

129492270(DCK)

MCC:	705040(DCK)

MCF:	101925611(DCK)

MTHB:

126955144

MNI:	105477325(DCK)

CSAB:

103235762(DCK)

CATY:

105596209(DCK)

PANU:

101006288(DCK)

TGE:	112624551(DCK)

MLEU:

105552465(DCK)

RRO:	104678729(DCK)

RBB:	108534027(DCK)

TFN:	117085514(DCK)

PTEH:

111524922(DCK)

CANG:

105501267(DCK)

CJC:	100395055(DCK)

SBQ:	101045176(DCK)

CIMI:

108284746(DCK)

ANAN:

105725399(DCK)

CSYR:

103265560(DCK)

MMUR:

105883058(DCK)

LCAT:

123624527(DCK)

PCOQ:

105822802(DCK)

OGA:	100943091(DCK)

MMU:	13178(Dck)

MCAL:

110294384(Dck)

MPAH:

110330622(Dck)

RNO:	79127(Dck)

MCOC:

116071457(Dck)

ANU:	117713148(Dck)

ASYL:

127696091(Dck)

MUN:	110540094(Dck)

CGE:	100751299(Dck)

MAUA:

101838564(Dck) 121136173

PROB:

127232156(Dck)

PLEU:

114686564 114688529 114706643(Dck)

MORG:

121460619(Dck)

MFOT:

126506586

AAMP:

119820312(Dck)

NGI:	103730983(Dck)

HGL:	101722212(Dck)

CPOC:

100713916(Dck)

CCAN:

109679520(Dck)

DORD:

105988448(Dck)

DSP:	122106714(Dck) 122123501

PLOP:

125364443(Dck)

NCAR:

124994589

MMMA:

107158810(Dck)

ITI:	101969704(Dck)

OCU:

100348589

OPI:	101523643(DCK)

TUP:	102498967(DCK)

GVR:	103599368(DCK)

CFA:	482188(DCK)

CLUD:

112652229(DCK) 112670684

VVP:	112923681(DCK)

VLG:	121472545(DCK)

NPO:	129503267(DCK)

AML:	100482093(DCK)

UMR:	103665295(DCK)

UAH:	113263298(DCK)

UAR:	123786920(DCK)

ELK:

111149150

LLV:

125093802

MPUF:

101683216(DCK)

MNP:	132006943(DCK)

MLK:	131823349(DCK)

NVS:	122889523(DCK)

ORO:	101384844(DCK)

EJU:	114206841(DCK)

ZCA:	113924835(DCK)

MLX:	118010467(DCK)

NSU:	110591474(DCK)

LWW:	102729901(DCK)

FCA:	101083845(DCK)

PYU:	121034655(DCK)

PCOO:

112858516(DCK)

PBG:	122478823(DCK)

PVIV:

125164698(DCK)

LRUF:

124520339

LGF:	123595892(DCK)

AJU:

106983696

PTG:	102949132(DCK)

PPAD:

109278016(DCK)

PUC:

125922797

PLEZ:

122218164(DCK)

HHV:	120244947(DCK)

BTA:	530642(DCK)

BOM:	102268258(DCK)

BIU:	109560557(DCK)

BBUB:

102404885(DCK)

BBIS:

104987963(DCK)

CHX:	102175015(DCK)

OAS:	101123378(DCK)

BTAX:

128049910(DCK)

CSUM:

138082264(DCK)

ODA:	120861414(DCK)

CCAD:

122428328(DCK)

MREE:

136152927(DCK)

OVR:	110126653(DCK)

MBEZ:

129562041(DCK)

SSC:	100517354(DCK)

CFR:	102524113(DCK)

CBAI:

105080397(DCK)

CDK:	105091182(DCK)

VPC:	102529516(DCK)

BACU:

103015268(DCK)

BMUS:

118896162(DCK)

LVE:	103071330(DCK)

OOR:	101281945(DCK)

LALB:

132519796(DCK)

DLE:	111187681(DCK)

PCAD:

102976054(DCK)

PSIU:

116754165(DCK)

NASI:

112405694(DCK)

ECB:	100054704(DCK)

EPZ:	103560855(DCK)

EAI:	106835100(DCK)

MYB:	102246003 102261934(DCK)

MYD:	102766950(DCK)

MMYO:

118669685(DCK)

MLF:	102435442(DCK)

MDT:	132218234(DCK)

MYUM:

138994952(DCK)

PKL:	118705514(DCK)

EFUS:

103300591(DCK)

MNA:	107532650(DCK)

DRO:	112320588(DCK)

SHON:

118999100(DCK)

AJM:	119051704(DCK)

PDIC:

114492299(DCK)

PHAS:

123831219(DCK)

MMF:	118637208(DCK)

PPAM:

129083782(DCK)

HAI:	109393701(DCK)

RFQ:	117022625(DCK)

PALE:

102890176(DCK)

PGIG:

120588176(DCK)

PVP:	105292330(DCK)

RAY:	107504025(DCK)

MJV:	108394228(DCK)

TOD:	119260792(DCK)

SARA:

101549226(DCK)

SFUM:

130020762(DCK)

SETR:

126032258(DCK)

LAV:	100667514(DCK)

TMU:

101361286

ETF:	101660769(DCK)

DNM:	101427738(DCK)

MDO:	100014536(DCK)

GAS:	123252199(DCK)

SHR:	100931780(DCK)

AFZ:

127540204

PCW:	110209808(DCK)

TVP:	118853743(DCK)

PBRV:

138163907(DCK)

OAA:	100078818(DCK)

TACU:

119939487(DCK)

GGA:	422648(DCK) 770922(DGUOK)

PCOC:

116231179(DCK) 116232174

MGP:	100544492(DCK) 100551225

CJO:	107313354(DCK) 107320138

TPAI:

128080722(DCK) 128081470

LMUT:

125692347(DCK) 125700045

NMEL:

110398815(DCK) 110405511

APLA:

101799591(DCK) 101804573

ACYG:

106032673 106043942(DCK)

CATA:

118245553(DCK) 118254905

AFUL:

116489205(DCK) 116494703

TGU:	100220427 100223331(DCK)

LSR:	110470157(DCK) 110482771

SCAN:

103817288 103823424(DCK)

PMOA:

120498760 120498772(DCK)

OTC:	121332426 121348175(DCK)

PRUF:

121349346(DCK) 121361421

ATRC:

139592586(DCK) 139597710

GFR:	102035084(DCK) 102038779

FAB:	101806066 101811376(DCK)

OMA:	130252673(DCK) 130258975

PHI:	102106204(DCK) 102108269

PMAJ:

107203117(DCK) 107210687

CCAE:

111929482(DCK) 111945349

CCW:	104689701 104696860(DCK)

CBRC:

103611393 103618957(DCK)

ACOE:

138109263(DCK) 138118112

ETL:	114060048(DCK) 114065212

ZAB:	102072849(DCK)

ZLE:	135447418(DCK) 135453780

ACHL:

103797246(DCK) 103798118

SVG:	106858317(DCK) 106859571

MMEA:

130577971 130581754(DCK)

HRT:	120752885(DCK) 120759179

SATI:

136360747(DCK) 136367472

CCIC:

134044722(DCK) 134049432

FPG:	101917700(DCK) 101920025

FCH:	102055990 102056086(DCK)

CCRI:

104156052 104164880(DCK)

NNT:	104400261 104400305 104411058

SHAB:

115605688 115610649(DCK) 115616164

ACUN:

113479483(DCK) 113485095

TALA:

104356318 104367925(DCK)

ACHC:

115334442 115346113(DCK)

HALD:

104311230(DCK) 104311589

HLE:	104836765(DCK)

AGEN:

126044738 126050813

HHAR:

128153217(DCK) 128154900

GCL:	127015772 127022084

CSTI:

104551123(DCK)

LDI:	104351336 104353447(DCK)

MNB:	103771722(DCK) 103778659

DPUB:

104296171(DCK) 104309902

PPUS:

135178968(DCK) 135185393

AVIT:

104279036 104280033(DCK)

BRHI:

104488305(DCK) 104493492

EGZ:	104125173(DCK) 104128441

NNI:	104011376(DCK) 104018457

PCRI:

104025699 104032869(DCK)

PCAO:

104044371(DCK) 104050706

PADL:

103915830 103916970(DCK)

AFOR:

103904400 103906883(DCK)

FGA:	104070687 104077134(DCK)

GSTE:

104251366 104255294(DCK)

CLV:	102091484 102092948(DCK)

MUI:	104535020 104541369(DCK)

PGUU:

104459189(DCK) 104459414

PLET:

104614110 104620154(DCK)

EHS:	104504346 104504482

CMAC:

104474630 104486145(DCK)

CUCA:

104059872 104063886(DCK)

TEO:	104370950 104377277

BREG:

104633735(DCK)

OHA:	104326914 104330338(DCK)

ACAR:

104518883 104523678(DCK)

CPEA:

104386908 104398418(DCK)

CVF:	104287766(DCK) 104293144

RTD:	128909885(DCK) 128916382

CRID:

134516079(DCK) 134522035

AAM:	106491894(DCK) 106493434

AROW:

112964792 112977629(DCK)

NPD:	112950276(DCK) 112954307

TGT:	104571341 104577372(DCK)

DNE:	112985133(DCK) 112996956

SCAM:

104142313 104152123(DCK)

ASN:	102381619(DCK) 102382818

AMJ:	102572880(DCK) 102575265

CPOO:

109309490(DCK) 109310146

GGN:	109289907 109297148(DCK)

PSS:	102444422(DCK)

CMY:	102946796(DCK)

CCAY:

125635612(DCK)

DCC:	119855251(DCK)

CPIC:

101948329(DCK)

TST:	117878441(DCK)

CABI:

116817716(DCK)

MRV:	120405638(DCK)

ACS:	100554557(dck) 100557346

ASAO:

132768932 132777081(DCK)

PVT:	110073482 110085258(DCK)

SUND:

121920929 121932116(DCK)

PBI:	103059568(DCK)

PMUR:

107289800(DCK)

CTIG:

120311152(DCK)

TSR:	106550977(DCK)

PGUT:

117673708(DCK)

APRI:

131202818(DCK)

PTEX:

113447175(DCK)

NSS:	113417877(DCK)

VKO:	123022656(DCK) 123035949

PMUA:

114591328 114604270 114604356

PRAF:

128407943 128421505(DCK)

ZVI:	118079063(DCK) 118080404

HCG:	128328438(DCK) 128344172

GJA:	107123240 107123770(DCK)

STOW:

125425177(DCK) 125430261

EMC:	129329020 129336797(DCK)

XLA:	108710975(dck.1l.L) 446773(dck.2.L) 494987(dck.1.L) 496391(dck.1.S)

XTR:	549546(dck.2) 594934(dck.1)

NPR:	108784695(DCK) 108797251

RTEM:

120915487(DCK) 120932441

BBUF:

120989686(DCK) 121003868

BGAR:

122926083(DCK) 122939815

PWL:	138245592 138298346(DCK)

MUO:	115462107(DCK)

GSH:	117367972(DCK)

DRE:	474325(dck) 541538(zgc:110540)

SRX:	107715300 107720908 107752943 107756157

SANH:

107661628 107669325 107675719(dck) 107700028

SGH:	107548225 107559410 107584655 107585435

CCAR:

109057974(dck) 109061511 109074621(zgc:110540)

CAUA:

113038535 113038955 113063768 113064339 113064402 113075727 113079983

CGIB:

127941400 127941402 127985390 127985472

PTET:

122326708(zgc:110540) 122340977(dck)

LROH:

127152389(zgc:110540) 127152689(dck)

OMC:	131528173(dck) 131529411(zgc:110540)

PPRM:

120470266(dck) 120494732(zgc:110540)

MAMB:

125252607(zgc:110540) 125253045(dck)

CIDE:

127503754 127504195(zgc:110540)

CERY:

137012655(zgc:110540) 137013358

MASI:

127428651(zgc:110540) 127428751 127431143

TROS:

130570376(zgc:110540) 130570589(dck)

TDW:	130407944(zgc:110540) 130408020(dck)

MANU:

129423130(dck) 129424452(zgc:110540)

PDAB:

135721545(dck) 135776878(zgc:110540)

IPU:	108278442(zgc:110540) 108279081

IFU:	128622780(zgc:110540) 128622824(dck)

PHYP:

113535609(dck) 113541634

SMEO:

124397580(zgc:110540) 124397958(dck)

TFD:	113646544(dck) 113646885(zgc:110540)

TVC:	132859813(dck) 132859845(zgc:110540)

CGAR:

128507135(zgc:110540) 128507902(dck)

NGRA:

132895319(dck) 132895593(zgc:110540)

TRN:	134330274(zgc:110540) 134330455(dck)

AMEX:

103029689(zgc:110540) 103043253(dck)

CMAO:

118820086(zgc:110540) 118820462(dck)

EEE:	113590818(dck) 113591964

CHAR:

105907442(zgc:110540) 105911484(dck)

SPIL:

134079553(zgc:110540) 134100764(dck)

TRU:	101065882(dck)

TFS:	130517132(dck) 130537512(zgc:110540)

TNG:	GSTEN00014362G001 GSTEN00014659G001

LCO:	104922470(dck) 104932480

NCC:	104952207(dck)

TBEN:

117476455(dck)

CGOB:

115016407(dck)

PGEO:

117456168(dck)

GACU:

117561394(dck)

EMAC:

134868177(dck)

ELY:	117263914(zgc:110540) 117269409(dck)

EFO:	125878662(dck) 125898207(zgc:110540)

PLEP:

121952244(zgc:110540) 121959865(dck)

SLUC:

116062373 116063013(dck)

ECRA:

117958820(dck)

ESP:	116704722(dck)

PFLV:

114566804 114571588(dck)

GAT:

120832171

PPUG:

119226862(dck)

AFB:	129102383(dck) 129113442

CLUM:

117740817(dck) 117743173(zgc:110540)

PSWI:

130206434(dck)

CANA:

137783512(dck)

CVE:	137868699(dck)

MSAM:

119895250(zgc:110540) 119914098(dck)

SCHU:

122865904(dck) 122888278

CUD:	121518407(zgc:110540) 121525243(dck)

SPUL:

138597501 138602161(dck)

LMIX:

132988381 132992399(dck)

ALAT:

119029614(dck) 119031668

ASTR:

137606388 137608564(dck)

MZE:	101465766 101485167(dck)

ONL:	100706399(dck) 100710536

OAU:	116316089(dck) 116331676(zgc:110540)

OLA:	101155710 101157232(dck)

OML:	112141695 112162744(dck)

XMA:	102219923(dck) 102220081

XCO:	114149449(dck) 114152520

XHE:	116724254(dck) 116728625

PRET:

103459907 103473357(dck)

PFOR:

103135877(dck) 103141066

PLAI:

106948554 106963593(dck)

PMEI:

106918549 106923796(dck)

GAF:	122819602(dck) 122844823(zgc:110540)

PPRL:

129370753 129374074(dck)

CVG:	107090340 107093354(dck) 107102290

CTUL:

119785585 119796438(dck)

GMU:	124872579(dck) 124876259(zgc:110540)

NFU:	107373220 107395118(dck)

KMR:	108242605(dck) 108250878

ALIM:

106511806 106528779 106531498(dck)

NWH:	119424284(dck)

AOCE:

111563398 111565434(dck)

EJA:

138209594

BFRE:

138622236(dck)

MCEP:

124996505(dck) 125021395(zgc:110540)

CSEM:

103389988(dck)

POV:	109626045(dck) 109642212(dguok)

SSEN:

122780190(zgc:110540) 122787019(dck)

SSOE:

131445866(dck) 131458467(zgc:110540)

HHIP:

117759014 117759015 117772112(dck)

HSP:	118122042 118125709(dck)

PPLT:

128456586 128462339(dck)

SMAU:

118284860(dck) 118300843

LCF:	108873608 108883003

SDU:	111220806(dck) 111239543

SLAL:

111649624 111666774(dck) 111671147

XGL:	120802159(zgc:110540) 120806010(dck)

HCQ:	109525557(dck)

SSCV:

125979309(dck)

SBIA:

133490779(dck) 133491398(zgc:110540)

PEE:	133413795(dck) 133416397

PTAO:

133465280(dck)

BPEC:

110157441(dck) 110175010

ENY:	140367235(dck) 140372547

MALB:

109969767(dck)

BSPL:

114867182(dck)

SJO:	128371848 128380314(dck)

SSCO:

133993707 133995361(dck)

GMH:	115541397(dck) 115547864

SASA:

100196160(dck) 106603918

STRU:

115153923 115159860(dck)

OTW:	112220161 112228262(zgc:110540)

OMY:	100305233(dck) 110533402(zgc:110540)

OGO:	124014515(zgc:110540) 124047935(dck)

ONE:	115120342 115136165

OKI:	109868562(dck) 109873072

OKE:	118373184(dck) 118389771(zgc:110540)

OMM:	135518187(dck) 135551023(zgc:110540)

OCLA:

139409876 139419411

SALP:

111950819 111961824 111964472

SNH:	120021551 120025898 120056423(zgc:110540)

CCLU:

121542182 121579158(zgc:110540) 121582150

ELS:	105011305 105027270(dck)

OEP:	134013612(zgc:110540) 134038606(dck)

SFM:	108934264 108938663 114912476(dck)

PKI:	111850184(dck)

AANG:

118212334(dck) 118234953(zgc:110540)

AROT:

135238819(dck) 135263647(zgc:110540)

CCOG:

133133001(zgc:110540) 133142165(dck)

LOC:	102684585(dck) 102692279

PSPA:

121300169 121324157(zgc:110540)

ARUT:

117403605 117403628 117403945 117404040 117413166 117431349 117963217

PSEX:

120532514 120543118

LCM:	102355337 102355687(DCK)

CMK:	103186473(zgc:110540) 103191301

RTP:	109932976(zgc:110540)

CPLA:

122539294 122543151 122556652(zgc:110540)

HOC:	132823200(zgc:110540) 132833300 132836821

LERI:

129701732(zgc:110540) 129713328

PMRN:

116944933 116950905(DCK)

LRJ:	133341806 133354381(DCK)

BFO:

BBEL:

CIN:

SCLV:

TPAL:

DFR:

PMEO:

AQU:

Reference

PMID:1996353

Authors

Chottiner EG, Shewach DS, Datta NS, Ashcraft E, Gribbin D, Ginsburg D, Fox IH, Mitchell BS

Title

Cloning and expression of human deoxycytidine kinase cDNA.

Journal

Proc Natl Acad Sci U S A 88:1531-5 (1991)
DOI:10.1073/pnas.88.4.1531

Sequence

[hsa:1633]

LinkDB

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