KEGG   ORTHOLOGY: K00983
Entry
K00983                      KO                                     
Symbol
neuA, nnaC
Name
N-acylneuraminate cytidylyltransferase [EC:2.7.7.43]
Pathway
map00520  Amino sugar and nucleotide sugar metabolism
map00541  O-Antigen nucleotide sugar biosynthesis
map01100  Metabolic pathways
map01250  Biosynthesis of nucleotide sugars
Module
M00922  CMP-Neu5Ac biosynthesis
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00520 Amino sugar and nucleotide sugar metabolism
    K00983  neuA, nnaC; N-acylneuraminate cytidylyltransferase
  09107 Glycan biosynthesis and metabolism
   00541 O-Antigen nucleotide sugar biosynthesis
    K00983  neuA, nnaC; N-acylneuraminate cytidylyltransferase
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.7  Nucleotidyltransferases
    2.7.7.43  N-acylneuraminate cytidylyltransferase
     K00983  neuA, nnaC; N-acylneuraminate cytidylyltransferase
Other DBs
RN: R01117 R04215
COG: COG1083
GO: 0008781
Genes
ECOO: ECRM13514_2761(nnaC)
ECOH: ECRM13516_2629(nnaC)
ESL: O3K_09235
ESO: O3O_16385
ESM: O3M_09200
ECK: EC55989_2294
ECV: APECO1_3472(neuA)
ECM: EcSMS35_3231(neuA)
ECT: ECIAI39_3442(neuA)
ECI: UTI89_C3371(neuA)
EIH: ECOK1_3368(neuA)
ECZ: ECS88_3329(neuA)
ECOI: ECOPMV1_03251(neuA)
SBZ: A464_2221
ETR: ETAE_1208(neuA)
ETD: ETAF_1123
ETE: ETEE_3152(neuA)
HIN: HI_1279
HIT: NTHI1891(siaB)
HIF: HIBPF_06650(siaB)
HIL: HICON_15140(siaB)
HIU: HIB_14310
HIE: R2846_0799(neuA)
HIZ: R2866_0861(neuA)
HIK: HifGL_000977(neuA)
HIA: H733_0891
HIW: NTHI477_00380(neuA)
HIC: NTHIC486_01386(neuA)
HIX: NTHI723_00291(neuA)
HPR: PARA_02840(nnaC)
HDU: HD_0685(neuA)
HHZ: NCTC10839_01659(neuA)
HAEG: NCTC8502_01754(neuA)
HAP: HAPS_0040(neuA1) HAPS_2206(neuA3)
PMU: PM0187(neuA)
PMV: PMCN06_1113(neuA)
PMP: Pmu_11260(neuA)
PMUL: DR93_1879(neuA)
PDAG: 4362423_01163(neuA)
MHQ: D650_8030
MHAT: B824_18210
MHX: MHH_c26660(nnaC)
MHAE: F382_04085
MHAM: J450_03115
MHAO: J451_04325
MHAL: N220_10185
MHAQ: WC39_04020
MHAY: VK67_04020
MVR: X781_6000
MVE: X875_5520
ADP: NCTC12871_01317(neuA)
BTO: WQG_15700
BTRE: F542_6360
BTRH: F543_7540
BTRA: F544_16050
VSA: VSAL_I3012(neuA)
NME: NMB0069(siaB)
NMP: NMBB_0073A(siaB)
NMQ: NMBM04240196_0081(siaB)
NMZ: NMBNZ0533_0075(siaB)
NMC: NMC0053(siaB)
NMN: NMCC_0077(siaB)
NMT: NMV_0070(siaB)
BPSI: IX83_06870
CJE: Cj1143(neuA1)
CJB: BN148_1143(neuA1)
CJI: CJSA_1085(neuA1)
CJEJ: N564_01109
CJEU: N565_01152
CJEN: N755_01147
CJEI: N135_01180
CMUC: CMCT_1130(neuA)
CNV: CNZW441b_1141(neuA)
DBK: DGMP_13680(neuA_2)
LGZ: NCTC10812_01044(neuA)
GHA: NCTC10459_01449(neuA)
SAG: SAG1158(neuA)
SAN: neuA
SAK: SAK_1247(neuA)
SGC: A964_1131(neuA)
SAGS: SaSA20_0980(neuA)
SAGL: GBS222_0990(neuA)
SAGM: BSA_12360
SAGI: MSA_12780
SAGR: SAIL_12780
SAGP: V193_05410
SAGC: DN94_05410
SAGE: EN72_06440
SAGG: EN73_05975
SAGN: W903_1241
SSB: SSUBM407_1277(neuA)
SSI: SSU0538(neuA)
SSS: SSUSC84_0520(neuA)
SSF: SSUA7_0541(neuA)
SUP: YYK_02550
SUI: SSUJS14_0545(neuA)
SUO: SSU12_0542(neuA)
SRP: SSUST1_1224(neuA)
SSUT: TL13_1185(cps16V)
SSUI: T15_1398(neuA)
SMEN: SAMEA4412692_0119(cps16V)
LIL: LA_1615(neuA)
LIE: LIF_A1302(neuA)
LIC: LIC_12167
AG: EDK88892(neuA)
 » show all
Reference
PMID:2549035
  Authors
Zapata G, Vann WF, Aaronson W, Lewis MS, Moos M
  Title
Sequence of the cloned Escherichia coli K1 CMP-N-acetylneuraminic acid synthetase gene.
  Journal
J Biol Chem 264:14769-74 (1989)
Reference
  Authors
Lewis AL, Robinson LS, Agarwal K, Lewis WG
  Title
Discovery and characterization of de novo sialic acid biosynthesis in the phylum Fusobacterium.
  Journal
Glycobiology 26:1107-1119 (2016)
DOI:10.1093/glycob/cww068
  Sequence
Reference
  Authors
Feng L, Senchenkova SN, Tao J, Shashkov AS, Liu B, Shevelev SD, Reeves PR, Xu J, Knirel YA, Wang L
  Title
Structural and genetic characterization of enterohemorrhagic Escherichia coli O145 O antigen and development of an O145 serogroup-specific PCR assay.
  Journal
J Bacteriol 187:758-64 (2005)
DOI:10.1128/JB.187.2.758-764.2005
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