KEGG ORTHOLOGY: K01316

ORTHOLOGY: K01316

Entry

K01316                      KO

Symbol

TMPRSS15, PRSS7

Name

enterokinase [EC:3.4.21.9]

Disease

H00988

Enterokinase deficiency

Brite

KEGG Orthology (KO) [BR:ko00001]
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors
    K01316  TMPRSS15, PRSS7; enterokinase
Enzymes [BR:ko01000]
3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.21  Serine endopeptidases
    3.4.21.9  enteropeptidase
     K01316  TMPRSS15, PRSS7; enterokinase
Peptidases and inhibitors [BR:ko01002]
Serine peptidases
  Family S1: chymotrypsin family
   K01316  TMPRSS15, PRSS7; enterokinase

Genes

HSA:	5651(TMPRSS15)

PTR:	129135269(TMPRSS15)

PPS:	100992890(TMPRSS15)

GGO:	101151821(TMPRSS15)

PON:	100431479(TMPRSS15)

PPYG:

129022569(TMPRSS15)

NLE:	100580929(TMPRSS15)

HMH:	116481539(TMPRSS15)

SSYN:

129482853(TMPRSS15)

MCC:	100423099(TMPRSS15)

MCF:	102135270(TMPRSS15)

MTHB:

126949617

MNI:	105498551(TMPRSS15)

CSAB:

103218091(TMPRSS15)

CATY:

105571817(TMPRSS15)

PANU:

101015783(TMPRSS15)

TGE:	112621093(TMPRSS15)

MLEU:

105543119(TMPRSS15)

RRO:	104673912(TMPRSS15)

RBB:	108543352(TMPRSS15)

TFN:	117095614(TMPRSS15)

PTEH:

111553001(TMPRSS15)

CANG:

105500836(TMPRSS15)

CJC:	100401965(TMPRSS15)

SBQ:	101053552(TMPRSS15)

CIMI:

108311893(TMPRSS15)

ANAN:

105711852(TMPRSS15)

CSYR:

103257634(TMPRSS15)

MMUR:

105883088(TMPRSS15)

LCAT:

123650155(TMPRSS15)

ERUF:

138385693(TMPRSS15)

PCOQ:

105809218(TMPRSS15)

OGA:	100951626(TMPRSS15)

MMU:	19146(Tmprss15)

MCAL:

110311705(Tmprss15)

MPAH:

110329794(Tmprss15)

RNO:	288291(Tmprss15)

MCOC:

116083601(Tmprss15)

ANU:	117717641(Tmprss15)

ASYL:

127666083(Tmprss15)

MUN:	110539510(Tmprss15)

CGE:	100754500(Tmprss15)

MAUA:

101825304(Tmprss15)

PROB:

127227446(Tmprss15)

PLEU:

114701917(Tmprss15)

PMAV:

102925524(Tmprss15)

MORG:

121465316(Tmprss15)

MFOT:

126505702

AAMP:

119825423(Tmprss15)

CNL:	130871935(Tmprss15)

NGI:	103732242(Tmprss15)

HGL:	101719326(Tmprss15)

CPOC:

100728703(Tmprss15)

CCAN:

109677737(Tmprss15)

DORD:

105996802(Tmprss15)

DSP:	122105659(Tmprss15)

DMER:

138831739(Tmprss15)

PLOP:

125351234(Tmprss15)

NCAR:

124993305

MMMA:

107136237(Tmprss15)

ITI:	101963901(Tmprss15)

OCU:

100350765

OPI:	101534557(TMPRSS15)

OCZ:	121156640(TMPRSS15)

TUP:	102474054(TMPRSS15)

CFA:	487700(TMPRSS15)

CLUD:

112661734(TMPRSS15)

VVP:	112917688(TMPRSS15)

VLG:	121479244(TMPRSS15)

NPO:	129502310(TMPRSS15)

AML:	100477756(TMPRSS15)

UMR:	103673186(TMPRSS15)

UAH:	113256976(TMPRSS15)

UAR:	123784394(TMPRSS15)

ELK:

111146811

LLV:

125095353

MPUF:

101683040(TMPRSS15)

MNP:	132010621(TMPRSS15)

MLK:	131825963(TMPRSS15)

NVS:	122910355(TMPRSS15)

ORO:	101363528(TMPRSS15)

EJU:	114217764(TMPRSS15)

ZCA:	113915858(TMPRSS15)

MLX:	118018771(TMPRSS15)

MANO:

123834542(TMPRSS15)

NSU:	110571168(TMPRSS15)

LWW:	102728067(TMPRSS15)

FCA:	101088868(TMPRSS15)

PYU:	121036479(TMPRSS15)

PCOO:

112849799(TMPRSS15)

PBG:	122491282(TMPRSS15)

PVIV:

125174404(TMPRSS15)

LRUF:

124527283

LGF:	123610687(TMPRSS15)

AJU:

106973146

PTG:	102969357(TMPRSS15)

PPAD:

109277847(TMPRSS15)

PUC:

125921735

PLEZ:

122230231(TMPRSS15)

HHV:	120246295(TMPRSS15)

CCRU:

144232783(TMPRSS15)

BTA:	282009(TMPRSS15)

BOM:	102265063(TMPRSS15)

BIU:	109559391(TMPRSS15)

BJV:	133253016(TMPRSS15)

BBUB:

102402700(TMPRSS15)

BKE:	129643370(TMPRSS15)

BBIS:

104997982(TMPRSS15)

CHX:	102180152(TMPRSS15)

OAS:	101115497(TMPRSS15)

OCAN:

138440279(TMPRSS15)

BTAX:

128055198(TMPRSS15)

CSUM:

138087155(TMPRSS15)

ODA:	120853539(TMPRSS15)

CCAD:

122428915(TMPRSS15)

MREE:

136152459(TMPRSS15)

OVR:	110145200(TMPRSS15)

MBEZ:

129550252(TMPRSS15)

SSC:	397152(TMPRSS15)

CFR:	102520122(TMPRSS15)

CBAI:

105072992(TMPRSS15)

CDK:	105086815(TMPRSS15)

VPC:	102525419(TMPRSS15)

BACU:

103001216(TMPRSS15)

BMUS:

118894440(TMPRSS15)

LVE:	103081000(TMPRSS15)

OOR:	101289210(TMPRSS15)

LALB:

132520677(TMPRSS15)

GMF:	115864263(TMPRSS15)

DDP:	132424003(TMPRSS15)

SCOO:

307187106(TMPRSS15)

DLE:	111175153(TMPRSS15)

PCAD:

102987176(TMPRSS15)

PSIU:

116753095(TMPRSS15)

PPHC:

136122932(TMPRSS15)

NASI:

112390941(TMPRSS15)

ECB:	100067591(TMPRSS15)

EPZ:	103550998(TMPRSS15)

EAI:	106846583(TMPRSS15)

MYB:	102249267(TMPRSS15)

MYD:	102770624(TMPRSS15)

MMYO:

118677405(TMPRSS15)

MLF:	102429319(TMPRSS15)

MDT:	132230014(TMPRSS15)

MYUM:

139004182(TMPRSS15)

PKL:	118724376(TMPRSS15)

EFUS:

103289745(TMPRSS15)

MNA:	107544677(TMPRSS15)

DRO:	112304515(TMPRSS15)

SHON:

118993293(TMPRSS15)

AJM:	119038634(TMPRSS15)

PDIC:

114491040(TMPRSS15)

PHAS:

123827286(TMPRSS15)

MMF:	118617200(TMPRSS15)

PPAM:

129072988(TMPRSS15)

HAI:	109391711(TMPRSS15)

RFQ:	117013799(TMPRSS15)

PALE:

102893141(TMPRSS15)

PGIG:

120598512(TMPRSS15)

PVP:	105290837(TMPRSS15)

RAY:	107512688(TMPRSS15)

MJV:	108394355(TMPRSS15)

TOD:	119257124(TMPRSS15)

SARA:

101540291(TMPRSS15)

SFUM:

130018640(TMPRSS15)

SETR:

126026020(TMPRSS15)

LAV:	100655543(TMPRSS15)

TMU:

101357439

ETF:	101655904(TMPRSS15)

DNM:	101422145(TMPRSS15)

MDO:	100020597(TMPRSS15)

GAS:	123239626(TMPRSS15)

SHR:	100928791(TMPRSS15)

AFZ:

127557153

PCW:	110214906(TMPRSS15)

TVP:	118839265(TMPRSS15)

PBRV:

138151309(TMPRSS15)

MLAO:

141504970(TMPRSS15)

OAA:	100079480(TMPRSS15)

TACU:

119945144(TMPRSS15)

GGA:	427967(TMPRSS15)

PCOC:

116242068(TMPRSS15)

MGP:	100547096(TMPRSS15)

CJO:	107322530(TMPRSS15)

TPAI:

128072753(TMPRSS15)

LMUT:

125696421(TMPRSS15)

NMEL:

110401927(TMPRSS15)

APLA:

101801915(TMPRSS15)

AACU:

137860215(TMPRSS15)

OJA:	118160601(TMPRSS15)

ACYG:

106036979(TMPRSS15)

CATA:

118247788(TMPRSS15)

AFUL:

116494033(TMPRSS15)

TGU:	100220466(TMPRSS15)

LSR:	110471651(TMPRSS15)

VMC:	128803177(TMPRSS15)

VCHA:

128783756(TMPRSS15)

AIB:	137468524(TMPRSS15)

SCAN:

103818409(TMPRSS15)

PMOA:

120504044(TMPRSS15)

OTC:	121341342(TMPRSS15)

PRUF:

121354546(TMPRSS15)

ATRC:

139593242(TMPRSS15)

MATE:

118685452(TMPRSS15)

MAEN:

136567874(TMPRSS15)

GFR:	102042374(TMPRSS15)

FAB:	101817773(TMPRSS15)

OMA:	130251202(TMPRSS15)

PHI:	102106374(TMPRSS15)

PMAJ:

107212126(TMPRSS15)

CCAE:

111940884(TMPRSS15)

CCW:	104689447(TMPRSS15)

CBRC:

103613745(TMPRSS15)

ACOE:

138117495(TMPRSS15)

ETL:	114058557(TMPRSS15)

ZAB:	102073361(TMPRSS15)

ZLE:	135442260(TMPRSS15)

ACHL:

103797326(TMPRSS15)

SVG:	106857499(TMPRSS15)

MMEA:

130575003(TMPRSS15)

HRT:	120748934(TMPRSS15)

SATI:

136373260(TMPRSS15)

CFAI:

136303124(TMPRSS15)

CCIC:

134054797(TMPRSS15)

NNT:	104413399(TMPRSS15)

SHAB:

115604185(TMPRSS15)

FPG:	101922858(TMPRSS15)

FCH:	102047221(TMPRSS15)

ACUN:

113481103(TMPRSS15)

TALA:

104365714(TMPRSS15)

ACHC:

115343949(TMPRSS15)

HLE:	104831807(TMPRSS15)

AGEN:

126048815

HHAR:

128145130(TMPRSS15)

BBUT:

142033697(TMPRSS15)

GCL:

127026038

LDI:	104344503(TMPRSS15)

MNB:	103779185(TMPRSS15)

DPUB:

104301506(TMPRSS15)

PPUS:

135179975(TMPRSS15)

AVIT:

104273674(TMPRSS15)

BRHI:

104492455(TMPRSS15)

EGZ:	104128144(TMPRSS15)

NNI:	104023355(TMPRSS15)

PCRI:

104033603(TMPRSS15)

PCAO:

104044661(TMPRSS15)

PARX:

142053194(TMPRSS15)

PADL:

103920211(TMPRSS15)

AFOR:

103902054(TMPRSS15)

CBOR:

142078062(TMPRSS15)

GSTE:

104254476(TMPRSS15)

CBOY:

140647783(TMPRSS15)

MAME:

142404839(TMPRSS15)

CLV:	102094803(TMPRSS15)

CNIC:

135992666(TMPRSS15)

MUI:	104547889(TMPRSS15)

PLET:

104621902(TMPRSS15)

EHS:	104514719(TMPRSS15)

CMAC:

104477387(TMPRSS15)

CUCA:

104068808(TMPRSS15)

TEO:	104372957(TMPRSS15)

OHA:	104331723(TMPRSS15)

ACAR:

104526389(TMPRSS15)

CPEA:

104387728(TMPRSS15)

CVF:	104285409(TMPRSS15)

RTD:	128905401(TMPRSS15)

CRID:

134518219(TMPRSS15)

LMIC:

141737612(TMPRSS15)

AAM:	106494880(TMPRSS15)

AROW:

112969651(TMPRSS15)

NPD:	112942846(TMPRSS15)

TGT:	104572373(TMPRSS15)

DNE:	112987899(TMPRSS15)

SCAM:

104139651(TMPRSS15)

ASN:	102380816(TMPRSS15)

AMJ:	102561133(TMPRSS15)

CPOO:

109305714(TMPRSS15)

GGN:	109302335(TMPRSS15)

PSS:	102446226(TMPRSS15)

CIZ:	142010913(TMPRSS15)

CMY:	102940846(TMPRSS15)

CCAY:

125631500(TMPRSS15)

LKP:	140905758(TMPRSS15)

NDS:	141983068(TMPRSS15)

DCC:	119842454(TMPRSS15)

CPIC:

101946023(TMPRSS15)

TST:	117877038(TMPRSS15)

CABI:

116828034(TMPRSS15)

MRV:	120407874(TMPRSS15)

EMQ:	137149395(TMPRSS15)

ACS:	100554809(tmprss15)

ASAO:

132770250(TMPRSS15)

PVT:	110074808(TMPRSS15)

SUND:

121925801(TMPRSS15)

PBI:	103048043(TMPRSS15)

PMUR:

107285869(TMPRSS15)

CTIG:

120310679(TMPRSS15)

TSR:	106550916(TMPRSS15)

PGUT:

117666163(TMPRSS15)

PCAE:

139316791(TMPRSS15)

APRI:

131199918(TMPRSS15)

PTEX:

113436418(TMPRSS15)

NSS:	113409750(TMPRSS15)

VKO:	123029135(TMPRSS15)

PMUA:

114596003(TMPRSS15)

PRAF:

128412934(TMPRSS15)

ZVI:	118084896(TMPRSS15)

HCG:	128350492(TMPRSS15)

GJA:	107113039(TMPRSS15)

STOW:

125431302(TMPRSS15)

EMC:	129326257(TMPRSS15)

XLA:

108709213

XTR:	100490249(tmprss15)

NPR:	108787208(TMPRSS15)

RTEM:

120927855(TMPRSS15)

ACAT:

141129199(TMPRSS15)

PADS:

140344979(TMPRSS15)

BGAR:

122931846(TMPRSS15)

DTC:	141097373(TMPRSS15)

PWL:	138249894(TMPRSS15)

MUO:	115471347(TMPRSS15)

GSH:	117359688(TMPRSS15)

DRE:	100148042(tmprss15)

DAES:

130215168(tmprss15)

SRX:	107757854(tmprss15)

SANH:

107668446(tmprss15)

SGH:	107603215(tmprss15)

CCAR:

109050978(tmprss15)

CAUA:

113063807 113063808

CGIB:

127941332

PTET:

122326480(tmprss15)

LROH:

127152100(tmprss15)

GRF:	141292725(tmprss15)

OMC:

131528188

PPRM:

120483194(tmprss15)

RKG:	130095504(tmprss15)

MAMB:

125253313(tmprss15)

CIDE:

127503545

CERY:

137013286(tmprss15)

MASI:

127429025 127431042

TROS:

130570607(tmprss15)

TDW:	130408078(tmprss15)

MANU:

129423055(tmprss15)

PDAB:

135776534(tmprss15)

IPU:	108278517(tmprss15)

IFU:	128622685(tmprss15)

PHYP:

113524594(tmprss15)

SMEO:

124397922(tmprss15)

TFD:	113650174(tmprss15)

TVC:	132860232(tmprss15)

CGAR:

128507124 128507712(tmprss15)

NGRA:

132895764(tmprss15)

TRN:	134330257(tmprss15)

CMAO:

118820473(tmprss15)

EEE:	113567777(tmprss15)

CHAR:

105892411(tmprss15)

SPIL:

134093467(tmprss15)

ASAD:

121724147(tmprss15)

TRU:	101079914(tmprss15)

TFS:	130537403(tmprss15)

TNG:	GSTEN00014573G001

TBEN:

117490689(tmprss15)

CGOB:

115005667 115005672

GACU:

117558951(tmprss15)

EMAC:

134871704(tmprss15)

EFO:	125898209(tmprss15)

SLUC:

116062361(tmprss15)

ECRA:

117956052

ESP:	116678413(tmprss15)

PFLV:

114566305(tmprss15)

GAT:	120822981(tmprss15)

PPUG:

119215881(tmprss15)

AFB:	129113795(tmprss15)

CLUM:

117742756(tmprss15)

PSWI:

130210115(tmprss15)

CANA:

137788064(tmprss15)

CVE:	137871488(tmprss15)

MSAM:

119895248(tmprss15)

SCHU:

122888271(tmprss15)

EARM:

139295121(tmprss15)

CUD:	121518603(tmprss15)

SPUL:

138599142(tmprss15)

LMIX:

132988387(tmprss15)

HTC:	141791732(tmprss15)

ALAT:

119031663(tmprss15)

ASTR:

137605919(tmprss15)

PKLU:

139224722(tmprss15)

LCO:	104919454(tmprss15)

MZE:	101483978(tmprss15)

ONL:	100710011(tmprss15)

OAU:	116331675(tmprss15)

OLA:	100125450(tmprss15)

OML:	112142496(tmprss15)

CSAI:

133460014(tmprss15)

XMA:	102229238(tmprss15)

XCO:	114152657(tmprss15)

XHE:	116728032(tmprss15)

PRET:

103459937(tmprss15)

PFOR:

103141088

PLAI:

106948544

PMEI:

106918539(tmprss15)

GAF:	122844820(tmprss15)

PPRL:

129370749(tmprss15)

CVG:	107102286(tmprss15)

CTUL:

119785592(tmprss15)

GMU:	124875954(tmprss15)

NFU:	107387187(tmprss15)

KMR:	108228482(tmprss15)

ALIM:

106536089(tmprss15)

NWH:	119420745(tmprss15)

LTU:	140279401(tmprss15)

MCEP:

125021393(tmprss15)

AOCE:

111575727 129350516

EJA:	138213614 138213617

BFRE:

138634847 138634862

LCF:

108873644

CSEM:

103395735(tmprss15)

POV:	109642208(tmprss15)

SSEN:

122780186(tmprss15)

SSOE:

131458616(tmprss15)

HHIP:

117759006 117759018

HSP:	118122374(tmprss15)

PPLT:

128457278(tmprss15)

SMAU:

118300840(tmprss15)

SDU:	111239500(tmprss15)

SLAL:

111671152(tmprss15)

XGL:	120802716(tmprss15)

HCQ:	109528878(tmprss15)

SSCV:

125981965(tmprss15)

SBIA:

133491363(tmprss15)

PEE:	133416395(tmprss15)

PTAO:

133467037(tmprss15)

BPEC:

110174990(tmprss15)

ENY:	140372543(tmprss15)

MALB:

109955105(tmprss15)

BSPL:

114870013(tmprss15)

SJO:	128371685(tmprss15)

SSCO:

133993635(tmprss15)

TTY:	137195096(tmprss15)

GMH:	115547974(tmprss15)

SASA:

106603180(tmprss15)

STRU:

115154775(tmprss15)

OTW:	112228897(tmprss15)

OMY:	110534073(tmprss15)

OGO:	124006809(tmprss15)

ONE:	115135556(tmprss15)

OKI:	109872715(tmprss15)

OKE:	118390443(tmprss15)

OMM:	135550344(tmprss15)

OCLA:

139419252

SALP:

111950203(tmprss15)

SNH:	120057579(tmprss15)

SFON:

129868999(tmprss15)

CCLU:

121580244(tmprss15)

ELS:	105027690 114828757

OEP:	134013555(tmprss15)

SFM:	108923738(tmprss15)

PKI:	111857254(tmprss15)

AANG:

118235531(tmprss15)

AROT:

135263120(tmprss15)

CCOG:

133133238(tmprss15)

LOC:	107076776(tmprss15)

PSPA:

121321272 121327799

ARUT:

117407202(tmprss15)

PSEX:

120524439(tmprss15)

LCM:	102345914(TMPRSS15)

CMK:	103189792(tmprss15)

CPLA:

122554852(tmprss15)

CPUN:

140486504(tmprss15)

HOC:	132820631(tmprss15)

SCAU:

119968635(tmprss15)

LERI:

129702497(tmprss15)

HAKA:

140727482(tmprss15)

PMRN:

116955838 116955839

LRJ:	133358477(TMPRSS15)

BFO:	118406284 118407219

BBEL:

109480386

SPU:	105439626 105441667 753320

AJJ:

AFIL:

SKO:

MSEX:

BANY:

PXU:

PRAP:

SLIU:

OFU:

OTU:

TPAL:

DMK:	116921727 123466273

HAZT:

PPOI:

RMP:

VDE:

DFR:

CRG:

MYI:

PMAX:

NVE:

ADF:	107329153 107345036 107358384

AMIL:

114961447 114971824 114974377 122950750

DGT:

114520451

XEN:

124444622

TAD:	TRIADDRAFT_53232

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Reference

PMID:23185382

Authors

Braud S, Ciufolini MA, Harosh I

Title

Enteropeptidase: a gene associated with a starvation human phenotype and a novel target for obesity treatment.

Journal

PLoS One 7:e49612 (2012)
DOI:10.1371/journal.pone.0049612

Sequence

[hsa:5651]

LinkDB

DBGET integrated database retrieval system