KEGG   ORTHOLOGY: K01342
Entry
K01342                      KO                                     
Symbol
aprE
Name
subtilisin [EC:3.4.21.62]
Brite
KEGG Orthology (KO) [BR:ko00001]
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors
    K01342  aprE; subtilisin
  09182 Protein families: genetic information processing
   03110 Chaperones and folding catalysts
    K01342  aprE; subtilisin
Enzymes [BR:ko01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.21  Serine endopeptidases
    3.4.21.62  subtilisin
     K01342  aprE; subtilisin
Peptidases and inhibitors [BR:ko01002]
 Serine peptidases
  Family S8: subtilisin family
   K01342  aprE; subtilisin
Chaperones and folding catalysts [BR:ko03110]
 Intramolecular chaperones
  Subtilisin family
   K01342  aprE; subtilisin
Other DBs
COG: COG1404
Genes
VNA: PN96_21170
VEJ: VEJY3_20426
VZI: G5S32_16115
VIO: AB2S62_19525
PAZO: AYR47_08420
PPUU: PputUW4_00217
PFZ: AV641_21465
PPSY: AOC04_18875
PVK: EPZ47_01330
PBZ: GN234_16695
PCAA: V6L78_02070
PAGR: E2H98_07725
SPSW: Sps_01013
PSPO: PSPO_b1036
PAEW: KIH87_09980
MII: BTJ40_12175
MICT: FIU95_10505(isp)
GAI: IMCC3135_18295(aprE)
TTC: FOKN1_1929
TOL: TOL_3513
TOR: R615_16425
AHA: AHA_3478
AHY: AHML_18455
AHD: AI20_01980
AHR: V428_19170
AHP: V429_19200
AHJ: V469_04105
AHH: RY45_17885
ADH: CK627_08380
CTI: RALTA_A2222
HPSE: HPF_14095
PBH: AAW51_0831
JAJ: EKL02_11675
MTIM: DIR46_22305
MASY: DPH57_21545
MASZ: C9I28_00125
MPLI: E1742_17405
DUG: HH213_00655
ARES: IWH25_04775
MLN: A9174_32325
RJG: CCGE525_36295 CCGE525_37610
RGR: FZ934_20880
AOL: S58_68990
BRQ: CIT40_26285
BGZ: XH91_13745
BSYM: CIT39_25275
MEE: DA075_32105
MSC: BN69_1924
MROS: EHO51_15640
DSH: Dshi_0257
PHAO: HF685_13840
ERK: CD351_04895
ERF: FIU90_00740(apr1)
ALI: AZOLI_p20735
DEX: HWD60_18910
GSK: KN400_2097
GPI: GPICK_05335
GAO: A2G06_06505
GEM: GM21_1195
GBM: Gbem_3055
PACE: A6070_09530
DML: Dmul_39070
DMM: dnm_002940
TRO: trd_1703
WCH: wcw_1929(aprE)
ROO: G5S37_11130
LUO: HHL09_13970
AMUC: Pan181_03070
PEH: Spb1_14850
PLS: VT03_06235(aprN)
GES: VT84_14990(apr_1) VT84_17225(aprN)
GOG: C1280_02115 C1280_14680
GMS: SOIL9_39940
TSPH: KIH39_11465
UAM: UABAM_01285 UABAM_04454
EPL: P4G45_07105
GEX: GETHOR_01810
FSU: Fisuc_0830
FSC: FSU_1274
PCRE: NCTC12858_00388
PCAG: NCTC12856_01031
PMUC: ING2E5A_2610(aprN)
PET: PEIBARAKI_4625
PSAC: PSM36_1910
PIT: PIN17_0039 PIN17_0041 PIN17_0436
MRUB: DEO27_008250
AHAP: V8V91_27350
SLI: Slin_1710 Slin_3456
SMON: AWR27_05265
SPIK: EXU85_27730
STAE: HNV11_15330 HNV11_19005
SOQ: LQ777_09535
SFOL: H3H32_09415
RUN: DR864_14560
RUP: DTQ70_23935
FAE: FAES_2745 FAES_3048(aprE)
FIB: A6C57_18545 A6C57_23130
HQI: H9L05_21120
HTB: MTX78_08195
PRHO: PZB74_14670
CLK: CGC53_00640
FAY: Q4Q34_15735
CJG: NCTC13459_00605(apr)
FTE: Fluta_2004
OHO: Oweho_0297
BSU: BSU10300(aprE)
BSR: I33_1162
BSL: A7A1_3704
BSH: BSU6051_10300(aprE)
BSY: I653_05205 I653_16335
BSUT: BSUB_01127(aprE)
BSUL: BSUA_01127(aprE)
BSUS: Q433_05825
BSO: BSNT_07467(aprN)
BSN: BSn5_17030
BSQ: B657_10300(aprE)
BSX: C663_1054(aprE) C663_3243(aprX)
BSP: U712_05250
BSS: BSUW23_05210(aprE)
BST: GYO_1328
BIT: BIS30_15855
BLI: BL01111(apr)
BLD: BLi01109(apr)
BLH: BaLi_c12310(aprE)
BAY: RBAM_010500
BAQ: BACAU_1010(aprE)
BYA: BANAU_0954(aprE)
BQY: MUS_1081(aprE)
BAMP: B938_05060
BAML: BAM5036_0953(aprE)
BAMA: RBAU_1012(aprE)
BAMN: BASU_0989(aprE)
BAMB: BAPNAU_2748(aprE)
BAMT: AJ82_05900
BAMY: V529_09920
BMP: NG74_01058(apr)
BAO: BAMF_1119(aprE)
BAZ: BAMTA208_04835(aprE)
BQL: LL3_01118(aprE)
BXH: BAXH7_01013(apr)
BAMI: KSO_014610
BAMC: U471_10430
BAMF: U722_05330
BSIA: CWD84_16485
BAE: BATR1942_02760
BVM: B9C48_05260
BSON: S101395_03724
BHT: DIC78_04470
BMOJ: HC660_10860(aprE)
BTEQ: G4P54_05465(aprE)
BIQ: AN935_05370
BSTR: QI003_05605(aprE)
BCX: BCA_4942
BCY: Bcer98_3892
BTL: BALH_4378
BWE: BcerKBAB4_5739
BPU: BPUM_0972
BPUM: BW16_05260 BW16_11335
BPUS: UP12_02845 UP12_05210 UP12_10600 UP12_18400
BIF: N288_23435
BGY: BGLY_1146(apr) BGLY_1970
BWH: A9C19_20320
BXI: BK049_03075 BK049_08985 BK049_16485
BALT: CFN77_05165 CFN77_11185
BAER: BAE_12730 BAE_18345
BSAF: BSL056_05155 BSL056_11625
BSHI: LGQ02_01210
BCAB: EFK13_05820(aprE)
BRY: M0696_05775(aprE)
BJS: MY9_1131
GST: HW35_12820
BACW: QR42_05055 QR42_10555
BACP: SB24_04625
BACB: OY17_07935
BACY: QF06_04075
BACL: BS34A_11440(aprE)
BALM: BsLM_1072
BACS: AUL54_05350
BZH: NF868_04460 NF868_09465
BAEI: RE735_09290 RE735_14380
BACF: AM500_16955
BAFC: K3G25_00830
BKN: WDJ61_17105
BHK: B4U37_08185 B4U37_08190
BCOH: BC6307_03110 BC6307_09490 BC6307_20400
BMQ: BMQ_pBM60006
BMH: BMWSH_p211(alp)
BMEG: BG04_5989
BFX: BC359_19465 BC359_20835 BC359_20895 BC359_20955
PKS: IE339_22580
BHA: BH0684(alp) BH0855
BCL: ABC0761(aprE)
BLE: BleG1_0395 BleG1_3277
SHUA: PQ477_04010 PQ477_10340
BGI: BGM20_20425
BPF: BpOF4_09070(subE) BpOF4_12080
BON: A361_05130 A361_05175
BKO: CKF48_03925
CGOT: J1899_03915 J1899_20685
CFIR: NAF01_04805
CSPG: LS684_19025
CPSS: M5V91_16640
CSUA: IM538_05940
LSP: Bsph_0341
LGY: T479_08835 T479_19860
LFU: HR49_04065
HMN: HM131_05010
HLI: HLI_15035
HAMY: MUO15_14510
VIG: BKP57_02100 BKP57_07055
FAR: ABE41_017340 ABE41_019275
APAK: AP3564_01855
ACOP: RI196_07180
BMUR: ABE28_015170
PASA: BAOM_2408(aprE)
PPSR: I6J18_07910 I6J18_17480
PSYH: D0S48_07750
PSYO: PB01_03765
POF: GS400_07575
PCHU: QNI29_08520
PONA: IMZ31_07075
MDG: K8L98_08770
MSEE: WCV65_18990
AIA: AWH56_020315
ROD: P8596_15635
PSUA: FLK61_40795
SLMS: MM221_07870
DOM: RRU94_10040
AHAL: FTX54_010725
GLI: GLN3_08620
GTN: GTNG_3101
GJF: M493_16490
GSR: GS3922_00340
PCAL: BV455_02091(aprE)
ANM: GFC28_2287
ANL: GFC29_3149
AND: GRQ40_04675
SHV: AAT16_04835 AAT16_09650
ESI: Exig_1251
EAN: Eab7_1202
EXM: U719_06490
EXU: ESP131_08900
EXH: HNY42_07930
BBE: BBR47_20780 BBR47_22370
BFM: BP422_05500 BP422_06405
BAGR: BA6348_22325
BRW: GOP56_11550
BCHS: JNE38_11680
BHUI: LOK74_05870
PJD: Pjdr2_0135
GYM: GYMC10_0122
PPM: PPSC2_00675(epr)
PPO: PPM_0127(epr)
PPQ: PPSQR21_001320(aprE)
PPOY: RE92_11030
PMS: KNP414_07652
PMQ: PM3016_7185
PMW: B2K_36240
PSAB: PSAB_00510
PDU: PDUR_00585
PGM: PGRAT_00580
POD: PODO_00595
PAEF: R50345_00610
PSTE: PSTEL_00945
PAEA: R70723_00565
PAEE: R70331_00580
PAEH: H70357_00585
PAEJ: H70737_00655
PRI: PRIO_0115 PRIO_6716(aprE)
PSON: JI735_08260
PPEO: ABE82_00685
PNP: IJ22_44650
POW: IJ21_02130
PXL: BS614_03610
PYG: AWM70_18485
PSWU: SY83_18965
PDH: B9T62_32665
PKB: B4V02_24585
PVO: PVOR_02741
PLW: D5F53_29015
PLEN: EIM92_04075
PPSC: EHS13_14370 EHS13_32420
PLUT: EI981_00565
PCHI: PC41400_29430
PBK: Back11_45130
PBAC: HUB98_17660
PRZ: GZH47_14975
PLYC: GXP70_02000
PSOP: KP014_03810
PTRI: KDC22_00575
PTJ: JRJ22_00580
PUI: PUW25_12650
PAUB: PUR_01060
TCO: Theco_3545
ASOC: CB4_03352(aprE)
ANEU: PP175_19920
COH: EAV92_20340
COHN: KCTCHS21_04720
AFX: JZ786_07280
SIV: SSIL_3520
SSIL: SOLI23_00835
PLN: Plano_0709
PRT: AUC31_05580
PLL: I858_003580
PANA: BBH88_16715
PDG: BCM40_12090
PHC: BBI08_09060 BBI08_16695
PMAR: B0X71_14850
PPLA: BBI15_00140
PLX: CW734_05890
PMAT: BBI11_05365
PDEC: H1Q58_04510
PGQ: FK545_12565
PLAY: DNR44_007855 DNR44_016300
PLIQ: QWY22_04930
PSHE: QWY16_15275
PSHX: QWY21_05025
JEO: JMA_06320 JMA_09790
SURE: SporoP32a_12710
SPOO: J3U78_14185
STRB: QWT68_10270
SOW: QWT69_16440
SJT: PGH26_01935
PANC: E2636_12390
NTR: B0W44_11455 B0W44_14375 B0W44_14495
LFB: C1X05_12925
TVU: AB849_007900
KPUL: GXN76_12330
KEB: GXN75_13860
PABS: JIR001_24090
CTH: Cthe_3137
STH: STH1033
DCA: Desca_0077
DFG: B0537_01205
DKU: Desku_1439
HMO: HM1_2600
CTHM: CFE_0732 CFE_0735
ANR: Ana3638_00755
EMJ: V1225_12045
EAC: EAL2_808p03370(epr)
MTHO: MOTHE_c20730(aprE)
MTHZ: MOTHA_c21500(aprE)
TOC: Toce_0485
NTH: Nther_2143
AAR: Acear_1993
GBX: SANA_03100
KPAR: JL105_08405
SSPH: SPSPH_045170
LPIL: LIP_0524
TPR: Tpau_1297
STIR: DDW44_06165
ALAV: MTO99_00660
LYD: D7I47_12140
ARL: AFL94_13945
ARU: ASPU41_03075
ACRY: AC20117_15780
ARTP: E5206_05210
ASUF: MNQ99_07240
ARTU: E7Y32_07625
AAI: AARI_27140
GCR: GcLGCM259_2901
GLU: F0M17_13330
ICA: Intca_0489
NOY: EXE57_14510
NOCA: ncot_18065
NCG: KGD84_24720
TCU: Tcur_1456
NCX: Nocox_04630(apr2)
NFS: OIE67_41885
SEN: SACE_3537
SACG: FDZ84_30800
PSEA: WY02_07925
PSEQ: AD006_24635
PECQ: AD017_04225
PHH: AFB00_21910
PAUT: Pdca_21980
KPHY: AOZ06_30845
ALO: CRK57421
SACE: GIY23_04895
ASE: ACPL_4119(aprA)
ACTS: ACWT_3990
AIH: Aiant_24880
PBAJ: LRS13_05360
LET: O77CONTIG1_01619
LBO: LBWT_56880
THEU: HPC62_19325
GDU: P0S91_08980
MIQ: B5D77_17445
CYT: cce_0328
NAZ: Aazo_1099
ANB: ANA_C13330
ACY: Anacy_0038
AWA: AA650_04050
RSIN: B6N60_03979
CALH: IJ00_14910
FIS: FIS3754_31010 FIS3754_47610
DOU: BMF77_00947(apr)
RCA: Rcas_2539
DDR: Deide_3p00270
DMR: Deima_0142
DGO: DGo_PA0262
DFC: DFI_19670
DPH: EHF33_20920
TSC: TSC_c03630(apr1)
THC: TCCBUS3UF1_1430
TOS: Theos_0005 Theos_1000
TAQ: TO73_2195
TBC: A0O31_01516
TANT: KNN15_06050
MRB: Mrub_0795 Mrub_1052
MRE: K649_03615 K649_04905
MTAI: Mtai_v1c28240
MSV: Mesil_3207 Mesil_3440
PHY: AJ81_02930
MPG: Theba_1167
MINF: MESINF_2231
AVE: Arcve_0834 Arcve_0894
FPL: Ferp_2094
THS: TES1_1967
THV: ADU37_CDS05690
TGG: A3K92_06795
PPAC: PAP_01675
MBAK: MSBR3_1511
MTHR: MSTHT_0610
MTHE: MSTHC_0110
MHOR: MSHOH_1113
MFZ: AOB57_013815
METW: AAY43_10525
MPY: Mpsy_0077
MZI: HWN40_07195
MMAV: RE476_03310
MSEB: RE474_12975
MHZ: Metho_2263
MPD: MCP_1283
HALX: M0R89_16480 M0R89_16485 M0R89_16490 M0R89_16495
HAXZ: M0R88_09685 M0R88_17075 M0R88_17085 M0R88_17090
HAYC: NGM10_06340 NGM10_14420 NGM10_14430 NGM10_14435 NGM10_14440
HAXY: NGM07_02950 NGM07_02955 NGM07_16990 NGM07_24425
HARA: AArcS_0205(aprE)
NSAL: HWV07_05120 HWV07_09995
HAAD: MW046_00465 MW046_00730 MW046_00885
HME: HFX_5138(aprE) HFX_5181(aprE)
HBO: Hbor_32310 Hbor_34040
HAQ: DU484_07355
HAJ: DU500_07470
HALM: FCF25_13890 FCF25_13895
HLA: Hlac_2196
HALN: B4589_002575
HALG: HUG10_06465
HALU: HUG12_10560
HRE: K6T36_05120
HACB: Hbl1158_11245
HDF: AArcSl_0415(aprE)
HAH: Halar_2141 Halar_2573
HTU: Htur_0058
HSAL: JMJ58_09075
HAKZ: J0X25_06810
NMG: Nmag_1874
HXA: Halxa_1240
NPE: Natpe_0106
NVR: FEJ81_00555
NAY: HYG81_10125
HJT: DVR14_09920
NGE: Natgr_3003 Natgr_3703
HLC: CHINAEXTREME11860
HRU: Halru_0481 Halru_0482
SAWL: NGM29_09345
HALV: NGM15_01570
NOU: Natoc_2188
HLR: HALLA_03780
HDA: BB347_14195
PFM: Pyrfu_1125
PDL: Pyrde_0048
THB: N186_08410
TCB: TCARB_0761
THF: MA03_03015
MVJ: ACO0C9_05610
NIW: Nisw_02775
TAA: NMY3_00666 NMY3_03174
NFN: NFRAN_0204
NIU: DSQ19_01525 DSQ19_03065
NCK: QVH35_11630
 » show all
Reference
PMID:3108260
  Authors
Ikemura H, Takagi H, Inouye M
  Title
Requirement of pro-sequence for the production of active subtilisin E in Escherichia coli.
  Journal
J Biol Chem 262:7859-64 (1987)
  Sequence
[bsu:BSU10300]
Reference
PMID:12705882
  Authors
Corvey C, Stein T, Dusterhus S, Karas M, Entian KD
  Title
Activation of subtilin precursors by Bacillus subtilis extracellular serine proteases subtilisin (AprE), WprA, and Vpr.
  Journal
Biochem Biophys Res Commun 304:48-54 (2003)
DOI:10.1016/S0006-291X(03)00529-1
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