KEGG   ORTHOLOGY: K01364
Entry
K01364                      KO                                     
Symbol
speB
Name
streptopain [EC:3.4.22.10]
Pathway
map01503  Cationic antimicrobial peptide (CAMP) resistance
map02024  Quorum sensing
Brite
KEGG Orthology (KO) [BR:ko00001]
 09140 Cellular Processes
  09145 Cellular community - prokaryotes
   02024 Quorum sensing
    K01364  speB; streptopain
 09160 Human Diseases
  09175 Drug resistance: antimicrobial
   01503 Cationic antimicrobial peptide (CAMP) resistance
    K01364  speB; streptopain
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors
    K01364  speB; streptopain
Enzymes [BR:ko01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.22  Cysteine endopeptidases
    3.4.22.10  streptopain
     K01364  speB; streptopain
Peptidases and inhibitors [BR:ko01002]
 Cysteine peptidases
  Family C10: streptopain family
   K01364  speB; streptopain
Genes
SPY: SPy_2039(speB)
SPZ: M5005_Spy1735(speB)
SPYM: M1GAS476_1785(speB)
SPYA: A20_1779c(speB)
SPM: spyM18_2099(speB)
SPG: SpyM3_1742(speB)
SPS: SPs1739
SPH: MGAS10270_Spy1803(speB)
SPI: MGAS10750_Spy1828(speB)
SPJ: MGAS2096_Spy1767(speB)
SPK: MGAS9429_Spy1743(speB)
SPF: SpyM51698(speB)
SPA: M6_Spy1735
SPB: M28_Spy1721(speB)
STG: MGAS15252_1579(speB)
STX: MGAS1882_1640(speB)
SOZ: Spy49_1690c(speB)
STZ: SPYALAB49_001716
SPYH: L897_08645
SPYO: STAB901_08450
SPSU: NCTC13786_00963(speB_1)
SPOC: NCTC10925_00258(speB_2)
SDID: N1495_01480
 » show all
Reference
PMID:7689226
  Authors
Kapur V, Majesky MW, Li LL, Black RA, Musser JM
  Title
Cleavage of interleukin 1 beta (IL-1 beta) precursor to produce active IL-1 beta by a conserved extracellular cysteine protease from Streptococcus pyogenes.
  Journal
Proc Natl Acad Sci U S A 90:7676-80 (1993)
DOI:10.1073/pnas.90.16.7676
Reference
PMID:10456871
  Authors
Tsai PJ, Lin YS, Kuo CF, Lei HY, Wu JJ
  Title
Group A Streptococcus induces apoptosis in human epithelial cells.
  Journal
Infect Immun 67:4334-9 (1999)
DOI:10.1128/IAI.67.9.4334-4339.1999
  Sequence
[spy:SPy_2039]
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