KEGG   ORTHOLOGY: K01401
Entry
K01401                      KO                                     
Symbol
aur
Name
aureolysin [EC:3.4.24.29]
Pathway
map01503  Cationic antimicrobial peptide (CAMP) resistance
map05150  Staphylococcus aureus infection
Brite
KEGG Orthology (KO) [BR:ko00001]
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05150 Staphylococcus aureus infection
    K01401  aur; aureolysin
  09175 Drug resistance: antimicrobial
   01503 Cationic antimicrobial peptide (CAMP) resistance
    K01401  aur; aureolysin
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors
    K01401  aur; aureolysin
Enzymes [BR:ko01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.24  Metalloendopeptidases
    3.4.24.29  aureolysin
     K01401  aur; aureolysin
Peptidases and inhibitors [BR:ko01002]
 Metallo peptidases
  Family M4: thermolysin family
   K01401  aur; aureolysin
Other DBs
COG: COG3227
Genes
SLIO: R50072_30720
SDO: SD1155_03045
SAU: SA2430(aur)
SAV: SAV2637(aur)
SAW: SAHV_2621(aur)
SAH: SaurJH1_2717
SAJ: SaurJH9_2661
SAM: MW2558(aur)
SAS: SAS2523
SAR: SAR2716(aur)
SAC: SACOL2659(aur)
SAX: USA300HOU_2637(aur)
SAA: SAUSA300_2572(aur)
SAO: SAOUHSC_02971
SAE: NWMN_2536(aur)
SAD: SAAV_2706(aur)
SUU: M013TW_2618(aur)
SUV: SAVC_12065
SUE: SAOV_2686c
SUJ: SAA6159_02533(aur)
SUK: SAA6008_02696(aur)
SUC: ECTR2_2491
SUT: SAT0131_02903
SUQ: HMPREF0772_10550(aur)
SUZ: MS7_2642(aur)
SUD: ST398NM01_2687
SUX: SAEMRSA15_25420(aur)
SUW: SATW20_27750(aur)
SUG: SAPIG2687
SUF: SARLGA251_24090(aur)
SAUA: SAAG_00459
SAUE: RSAU_002480(aur)
SAUN: SAKOR_02638
SAUS: SA40_2393(aur)
SAUU: SA957_2477(aur)
SAUG: SA268_2574(aur)
SAUZ: SAZ172_2756(aur)
SAUT: SAI1T1_2019740(aur)
SAUJ: SAI2T2_1019750(aur)
SAUK: SAI3T3_1019740(aur)
SAUQ: SAI4T8_1019750(aur)
SAUV: SAI7S6_1019740(aur)
SAUW: SAI5S5_1019680(aur)
SAUX: SAI6T6_1019690(aur)
SAUY: SAI8T7_1019720(aur)
SAUF: X998_2620
SAB: SAB2512c(aur)
SUY: SA2981_2576(aur)
SAUB: C248_2705(aur)
SAUM: BN843_26750
SAUC: CA347_2715
SAUR: SABB_04255(aur)
SAUI: AZ30_13795
SAUD: CH52_05820
SAMS: NI36_13265
SUH: SAMSHR1132_24610
SER: SERP2252(sepA)
SEP: SE_2219
SEPP: SEB_02220
SEPS: DP17_1151(sepA)
SSP: SSP1542
SSD: SPSINT_2146
SDT: SPSE_0326
SDP: NCTC12225_00398(aur)
SWA: A284_01205
SPAS: STP1_1156
SXY: BE24_03405
SXL: SXYLSMQ121_1581
SXO: SXYL_01658
SHU: SHYC_09855(aur)
SCAP: AYP1020_1844(sepA)
SSCH: LH95_01925
SSCZ: RN70_02240
SAGQ: EP23_00125
SEQO: SE1039_10430
SLZ: B5P37_04350
SCOH: BZ166_12190
SURY: MUA21_04545
SNL: BJD96_08540
SKL: C7J89_09685
SFQ: C7J90_00795
SCAR: DWB96_01280
SCHR: DWB92_10010
SARL: SAP2_16170
SSH: NCTC13712_02592(aur)
SSIM: SAMEA4384339_2444(aur)
SLLO: ISP08_07975
SRAI: LN051_08840
SPSD: JMB28_08605
SCAQ: QMO72_08495
SROT: ML435_12735(aur)
STAP: AOB58_720
SGAI: K3U27_03655
SSCU: CEP64_01805
SFF: FOB90_05845
SSTE: SAMEA4384403_0437(sepA_2)
MVT: I6J10_08920
MACR: BHM04_00285
MARY: LAU42_10755 LAU42_10760 LAU42_10765
MBRU: MGG13_02555 MGG13_09375
MEPI: KFV12_11115 KFV12_11980
MEQU: KFV11_09525
MBOC: QSV55_09645 QSV55_09650
MPSH: QA539_08925
MCL: MCCL_1675
MCAK: MCCS_05170(sepA_2) MCCS_23430(sepA_3)
MBOE: HT586_10410
PBIF: KXZ80_15765
PSOR: RSJ16_08260
 » show all
Reference
PMID:15561843
  Authors
Sieprawska-Lupa M, Mydel P, Krawczyk K, Wojcik K, Puklo M, Lupa B, Suder P, Silberring J, Reed M, Pohl J, Shafer W, McAleese F, Foster T, Travis J, Potempa J
  Title
Degradation of human antimicrobial peptide LL-37 by Staphylococcus aureus-derived proteinases.
  Journal
Antimicrob Agents Chemother 48:4673-9 (2004)
DOI:10.1128/AAC.48.12.4673-4679.2004
Reference
PMID:10639475
  Authors
Sabat A, Kosowska K, Poulsen K, Kasprowicz A, Sekowska A, van Den Burg B, Travis J, Potempa J
  Title
Two allelic forms of the aureolysin gene (aur) within Staphylococcus aureus.
  Journal
Infect Immun 68:973-6 (2000)
DOI:10.1128/IAI.68.2.973-976.2000
  Sequence
[suz:MS7_2642]
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