KEGG   ORTHOLOGY: K01565
Entry
K01565                      KO                                     
Symbol
SGSH
Name
N-sulfoglucosamine sulfohydrolase [EC:3.10.1.1]
Pathway
map00531  Glycosaminoglycan degradation
map01100  Metabolic pathways
map04142  Lysosome
Module
M00078  Heparan sulfate degradation
Disease
H00130  Mucopolysaccharidosis type III
H00421  Mucopolysaccharidosis
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09107 Glycan biosynthesis and metabolism
   00531 Glycosaminoglycan degradation
    K01565  SGSH; N-sulfoglucosamine sulfohydrolase
 09140 Cellular Processes
  09141 Transport and catabolism
   04142 Lysosome
    K01565  SGSH; N-sulfoglucosamine sulfohydrolase
Enzymes [BR:ko01000]
 3. Hydrolases
  3.10  Acting on sulfur-nitrogen bonds
   3.10.1  Acting on sulfur-nitrogen bonds (only sub-subclass identified to date)
    3.10.1.1  N-sulfoglucosamine sulfohydrolase
     K01565  SGSH; N-sulfoglucosamine sulfohydrolase
Other DBs
RN: R07814
GO: 0016250
Genes
HSA: 6448(SGSH)
PTR: 745502(SGSH)
PPS: 100985307(SGSH)
GGO: 101142618(SGSH)
PON: 100459478(SGSH)
NLE: 100588596(SGSH)
MCC: 717977(SGSH)
MCF: 102142565(SGSH)
CSAB: 103243692(SGSH)
CATY: 105588633(SGSH)
PANU: 101019018(SGSH)
TGE: 112609127(SGSH)
RRO: 104675244(SGSH)
RBB: 108534150(SGSH)
TFN: 117066800(SGSH)
PTEH: 111542330(SGSH)
CJC: 100411890(SGSH)
SBQ: 101040481(SGSH)
CSYR: 103257489(SGSH)
MMUR: 105866693(SGSH)
OGA: 100956569(SGSH)
MMU: 27029(Sgsh)
MCAL: 110304794(Sgsh)
MPAH: 110332344(Sgsh)
RNO: 688293(Sgsh)
MCOC: 116077213(Sgsh)
MUN: 110550081(Sgsh)
CGE: 100755391(Sgsh)
NGI: 103730575(Sgsh)
HGL: 101720611(Sgsh)
CPOC: 100728868(Sgsh)
CCAN: 109689941(Sgsh)
DORD: 106001145(Sgsh)
DSP: 122099370(Sgsh)
OPI: 101518572(SGSH)
TUP: 102473234(SGSH)
CFA: 403707(SGSH)
VVP: 112920674(SGSH)
VLG: 121474124(SGSH)
AML: 100477824(SGSH)
UMR: 103665802(SGSH)
UAH: 113244537(SGSH)
UAR: 123802983(SGSH)
ELK: 111160442
MPUF: 101688920(SGSH)
ORO: 101385912(SGSH)
EJU: 114216239(SGSH)
ZCA: 113939773(SGSH)
MLX: 118024193(SGSH)
FCA: 101094715(SGSH)
PYU: 121018024(SGSH)
PBG: 122486181(SGSH)
PTG: 102957138(SGSH)
PPAD: 109276815(SGSH)
AJU: 106981876(SGSH)
HHV: 120228151(SGSH)
BTA: 535442(SGSH)
BOM: 102274142(SGSH)
BIU: 109574273(SGSH)
BBUB: 102408571(SGSH)
CHX: 102175240(SGSH)
OAS: 101121184(SGSH)
ODA: 120866841(SGSH)
CCAD: 122438135(SGSH)
SSC: 100737146(SGSH)
CFR: 102511664(SGSH)
CBAI: 105065580(SGSH)
CDK: 105106252(SGSH)
BACU: 102997141(SGSH)
LVE: 103089895(SGSH)
OOR: 101289415(SGSH)
DLE: 111182732(SGSH)
PCAD: 102979953(SGSH)
PSIU: 116746061(SGSH)
ECB: 100056499(SGSH)
EPZ: 103547325(SGSH)
EAI: 106845569(SGSH)
MYB: 102239046(SGSH)
MYD: 102753251(SGSH)
MMYO: 118671232(SGSH)
MNA: 107532059(SGSH)
PKL: 118704505(SGSH)
HAI: 109383662(SGSH)
DRO: 112298704(SGSH)
SHON: 118999437(SGSH)
AJM: 119058533(SGSH)
PDIC: 114503187(SGSH)
PHAS: 123816840(SGSH)
MMF: 118634013(SGSH)
RFQ: 117013313(SGSH)
PALE: 102893583(SGSH)
PGIG: 120600100(SGSH)
PVP: 105305235(SGSH)
RAY: 107510086(SGSH)
MJV: 108410242(SGSH)
TOD: 119232100(SGSH)
SARA: 101545545(SGSH)
LAV: 100658885(SGSH)
TMU: 101346127
DNM: 101443773(SGSH)
MDO: 100030803(SGSH)
GAS: 123244254(SGSH)
SHR: 100932279(SGSH)
PCW: 110218200(SGSH)
OAA: 100079215(SGSH)
GGA: 422081(SGSH)
PCOC: 116232528(SGSH)
MGP: 100549132(SGSH)
CJO: 107322087(SGSH)
NMEL: 110407409(SGSH)
ACYG: 106046739(SGSH)
AFUL: 116496701(SGSH)
TGU: 100230664(SGSH)
LSR: 110472432(SGSH)
SCAN: 103819936(SGSH)
PMOA: 120505556(SGSH)
OTC: 121338448(SGSH) 121346566
PRUF: 121363415(SGSH)
GFR: 102037178(SGSH)
FAB: 101812983(SGSH)
PHI: 102110099(SGSH)
PMAJ: 107212385(SGSH)
CCAE: 111944975
CCW: 104698239(SGSH)
ETL: 114068232(SGSH)
FPG: 101918825(SGSH)
FCH: 102050903(SGSH)
CLV: 102090183(SGSH)
EGZ: 104130619(SGSH)
NNI: 104014329(SGSH)
TALA: 116963611(SGSH)
PADL: 103917442(SGSH)
ACHC: 115341963(SGSH)
AAM: 106484733 106485998(SGSH)
AROW: 112973728(SGSH)
NPD: 112945335(SGSH)
DNE: 112990910(SGSH)
ASN: 102382451(SGSH)
AMJ: 102576386(SGSH)
CPOO: 109314896(SGSH)
GGN: 109296262(SGSH)
PSS: 102460593(SGSH)
CMY: 102940151(SGSH)
CPIC: 101954045(SGSH)
TST: 117887342(SGSH)
CABI: 116834881(SGSH)
MRV: 120383168(SGSH)
ACS: 100561423(sgsh)
PVT: 110090123(SGSH)
SUND: 121921400(SGSH)
PBI: 103064462(SGSH)
PMUR: 107288798(SGSH)
TSR: 106541220(SGSH)
PGUT: 117662998(SGSH)
VKO: 123036910(SGSH)
PMUA: 114588986(SGSH)
ZVI: 118079703(SGSH)
GJA: 107119861(SGSH)
XLA: 495504(sgsh.L)
XTR: 100145064(sgsh)
NPR: 108792969(SGSH)
RTEM: 120919573(SGSH)
BBUF: 121003353(SGSH)
BGAR: 122942624(SGSH)
DRE: 563849(sgsh)
SRX: 107756031
SGH: 107586947(sgsh) 107593085
CCAR: 109047860
CAUA: 113064755(sgsh)
IPU: 108259505(sgsh)
PHYP: 113524254(sgsh)
SMEO: 124380025(sgsh)
AMEX: 103028698(sgsh)
EEE: 113585727(sgsh)
TRU: 101072409(sgsh)
LCO: 104930251(sgsh)
NCC: 104950013(sgsh)
CGOB: 115007890(sgsh)
ELY: 117254894(sgsh)
PLEP: 121941785(sgsh)
SLUC: 116042645(sgsh)
ECRA: 117959060(sgsh)
PFLV: 114573952(sgsh)
GAT: 120824777(sgsh)
PPUG: 119218210(sgsh)
CUD: 121508336(sgsh)
MZE: 101463965(sgsh)
ONL: 100699960(sgsh)
OAU: 116330798(sgsh)
OLA: 101155495(sgsh)
OML: 112137359(sgsh)
XMA: 102222374(sgsh)
XCO: 114144623(sgsh)
XHE: 116719941(sgsh)
PRET: 103465890(sgsh)
PLAI: 106960591(sgsh)
PMEI: 106917554(sgsh)
GAF: 122829630(sgsh)
CVG: 107103621(sgsh)
CTUL: 119783307(sgsh)
NFU: 107392187(sgsh)
KMR: 108236263(sgsh)
ALIM: 106534568(sgsh)
NWH: 119422818(sgsh)
AOCE: 111571894(sgsh)
CSEM: 103383950(sgsh) 103383953
POV: 109627331(sgsh)
SSEN: 122771152(sgsh)
HHIP: 117768808(sgsh)
LCF: 108875653(sgsh)
SDU: 111229298(sgsh)
SLAL: 111666628(sgsh)
XGL: 120800103(sgsh)
HCQ: 109527474(sgsh)
BPEC: 110165214(sgsh) 110165216
MALB: 109957842(sgsh)
SASA: 100195283(sphm) 106564344(SPHM)
OTW: 112237038(sgsh) 112242248
OGO: 124002725(sgsh)
ONE: 115128110(sgsh)
SALP: 112078376(sgsh)
ELS: 105012037(sgsh)
SFM: 108930233(sgsh)
PKI: 111846603(sgsh)
AANG: 118221422(sgsh)
LOC: 102687031(sgsh)
PSPA: 121296638
ARUT: 117424259
LCM: 102349697(SGSH)
CMK: 103175583(sgsh)
BFO: 118428791
BBEL: 109461930
CIN: 113474074
SCLV: 120342154
DME: Dmel_CG14291(Sgsh)
DER: 6553879
DSE: 6613707
DSI: Dsimw501_GD20144(Dsim_GD20144)
DAN: 6505660
DSR: 110186654
DPE: 113565741
DMN: 108157467
DWI: 6649855
DGR: 6563634
DAZ: 108621019
DNV: 108659592
DHE: 111604223
DVI: 6635108
CCAT: 101455311
BOD: 106616035
MDE: 101887821
SCAC: 106082956
LCQ: 111690399
ACOZ: 120949141
AARA: 120893958
AAG: 5573339
AALB: 109413692
CPII: 120426771
CNS: 116343686
AME: 550884
ACER: 108000124
ALAB: 122713638
BIM: 100747363
BBIF: 117213718
BVK: 117231385
BVAN: 117156570
BTER: 100645767
BPYO: 122572551
CCAL: 108625086
OBB: 114875231
MGEN: 117225641
NMEA: 116425802
CGIG: 122396452
SOC: 105205194
MPHA: 105835776
AEC: 105152566
ACEP: 105621840
PBAR: 105426128
VEM: 105566120
HST: 105188180
CFO: 105249090
FEX: 115235971
LHU: 105667524
PGC: 109858431
OBO: 105279540
PCF: 106793887
PFUC: 122526547
VPS: 122634396
NVI: 100119668
CSOL: 105362363
TPRE: 106657700
MDL: 103574073
CGLO: 123274866
FAS: 105273628
DAM: 107038722
AGIF: 122857702
CCIN: 107264631
TCA: 659261
DPA: 109541348
SOY: 115884687
ATD: 109594649
AGB: 108907276
NVL: 108561271
APLN: 108737232
PPYR: 116177611
OTU: 111426415
BMOR: 101737423
BMAN: 114244627
MSEX: 115448751
BANY: 112051443
PMAC: 106721422
PXU: 106118955
PRAP: 111002361
ZCE: 119832298
HAW: 110381460
TNL: 113508096
OFU: 114357940
PXY: 105387712
BTAB: 109035959
CLEC: 106663397
HHAL: 106686440
NLU: 111058669
FOC: 113209166
ZNE: 110832827
CSEC: 111862267
DMK: 116921354
PVM: 113823251
PJA: 122256830
HAME: 121866386
PCLA: 123754274
PTRU: 123513704
HAZT: 108683171
DSV: 119453309
RSAN: 119400169
CSCU: 111635290
PTEP: 107452892
SDM: 118181979
CRG: 105339838
MYI: 110448223
PMAX: 117334419
OBI: 106867433
OSN: 115218184
NVE: 5506258
EPA: 110255094
ATEN: 116299135
ADF: 107348323
AMIL: 114964843
DGT: 114527829
XEN: 124439540
AQU: 100638186
SSCK: SPSK_06264
ANG: ANI_1_1460064(An07g01010)
PEC: W5S_0662
CPS: CPS_2367
MMED: Mame_02677
MALG: MALG_04863
ANH: A6F65_00911(betC_1)
ADO: A6F68_00094(betC_1) A6F68_00808(betC_4)
GOH: B932_3172
PSAB: PSAB_07115
PSWU: SY83_13335
ARR: ARUE_c37330(sGSH)
ARM: ART_2646
RXY: Rxyl_2349
TTR: Tter_0440
CAA: Caka_0430
PIR: VN12_01650(atsA_4) VN12_04990(betC_1) VN12_10510(betC_2) VN12_12025(atsA_16) VN12_18880(betC_3)
RUL: UC8_02330(atsA_5) UC8_11520 UC8_11630(betC_3) UC8_17520 UC8_19110(atsA_23) UC8_20540(betC_5) UC8_37470(betC_9)
PLS: VT03_00585(betC_1) VT03_05165(atsA_4)
PLH: VT85_12930(betC_2)
GMR: GmarT_12620(atsA_6) GmarT_14400(atsA_8) GmarT_33210(atsA_17) GmarT_38040(betC_8) GmarT_46930 GmarT_53660 GmarT_56740(atsA_50) GmarT_58240(atsA_53)
GPN: Pan110_12470(atsA_5) Pan110_13780(atsA_7) Pan110_31220(atsA_20) Pan110_36280(betC_7) Pan110_45400 Pan110_50760(betC_10) Pan110_54400 Pan110_57850(atsA_63) Pan110_59530(betC_15)
MRI: Mal4_01630(betC_1) Mal4_12070 Mal4_12150 Mal4_12840(betC_4) Mal4_14250(betC_5) Mal4_23570 Mal4_30750(betC_14) Mal4_34910(atsA_45) Mal4_46290(betC_19) Mal4_57020(atsA_64)
SDYN: Mal52_16600(atsA_13) Mal52_25700(atsA_21) Mal52_53080(atsA_30)
PLON: Pla110_15660(atsA_6) Pla110_19280(atsA_11)
IPA: Isop_2942
PBP: STSP1_00691(atsA_13) STSP1_00706(betC_1) STSP1_00707(betC_2) STSP1_00800 STSP1_00966 STSP1_01854(betC_6)
SUS: Acid_4006
ABAC: LuPra_04148(betC_6)
GBA: J421_0703
BXY: BXY_28060
BOA: Bovatus_03639(atsA_13)
AFD: Alfi_3056
ASH: AL1_31000
DORI: FH5T_02580
CPI: Cpin_4597
PHE: Phep_2826
SDJ: NCTC13534_01305(betC_1)
SLI: Slin_4179
ZPR: ZPR_4386
MARM: YQ22_01925
ZGA: ZOBELLIA_2192(sgsA2) ZOBELLIA_2196(sgsA3) ZOBELLIA_2201(sgsA4) ZOBELLIA_2210(sgsA5) ZOBELLIA_2216(sgsA6)
HTU: Htur_3375
NMG: Nmag_3825
SALI: L593_00570
 » show all
Reference
PMID:7493035
  Authors
Scott HS, Blanch L, Guo XH, Freeman C, Orsborn A, Baker E, Sutherland GR, Morris CP, Hopwood JJ
  Title
Cloning of the sulphamidase gene and identification of mutations in Sanfilippo A syndrome.
  Journal
Nat Genet 11:465-7 (1995)
DOI:10.1038/ng1295-465
  Sequence
[hsa:6448]
LinkDB

KEGG   ENZYME: 3.10.1.1
Entry
EC 3.10.1.1                 Enzyme                                 
Name
N-sulfoglucosamine sulfohydrolase;
sulfoglucosamine sulfamidase;
heparin sulfamidase;
2-desoxy-D-glucoside-2-sulphamate sulphohydrolase (sulphamate sulphohydrolase)
Class
Hydrolases;
Acting on sulfur-nitrogen bonds;
Acting on sulfur-nitrogen bonds (only sub-subclass identified to date)
Sysname
N-sulfo-D-glucosamine sulfohydrolase
Reaction(IUBMB)
N-sulfo-D-glucosamine + H2O = D-glucosamine + sulfate [RN:R01963]
Reaction(KEGG)
R01963;
(other) R07814(G)
Substrate
N-sulfo-D-glucosamine [CPD:C01075];
H2O [CPD:C00001]
Product
D-glucosamine [CPD:C00329];
sulfate [CPD:C00059]
History
EC 3.10.1.1 created 1972, modified 1981, modified 1982
Pathway
ec00531  Glycosaminoglycan degradation
ec01100  Metabolic pathways
Orthology
K01565  N-sulfoglucosamine sulfohydrolase
Genes
HSA6448(SGSH)
PTR745502(SGSH)
PPS100985307(SGSH)
GGO101142618(SGSH)
PON100459478(SGSH)
NLE100588596(SGSH)
MCC717977(SGSH)
MCF102142565(SGSH)
CSAB103243692(SGSH)
CATY105588633(SGSH)
PANU101019018(SGSH)
TGE112609127(SGSH)
RRO104675244(SGSH)
RBB108534150(SGSH)
TFN117066800(SGSH)
PTEH111542330(SGSH)
CJC100411890(SGSH)
SBQ101040481(SGSH)
CSYR103257489(SGSH)
MMUR105866693(SGSH)
OGA100956569(SGSH)
MMU27029(Sgsh)
MCAL110304794(Sgsh)
MPAH110332344(Sgsh)
RNO688293(Sgsh)
MCOC116077213(Sgsh)
MUN110550081(Sgsh)
CGE100755391(Sgsh)
NGI103730575(Sgsh)
HGL101720611(Sgsh)
CPOC100728868(Sgsh)
CCAN109689941(Sgsh)
DORD106001145(Sgsh)
DSP122099370(Sgsh)
OPI101518572(SGSH)
TUP102473234(SGSH)
CFA403707(SGSH)
VVP112920674(SGSH)
VLG121474124(SGSH)
AML100477824(SGSH)
UMR103665802(SGSH)
UAH113244537(SGSH)
UAR123802983(SGSH)
ELK111160442
MPUF101688920(SGSH)
ORO101385912(SGSH)
EJU114216239(SGSH)
ZCA113939773(SGSH)
MLX118024193(SGSH)
FCA101094715(SGSH)
PYU121018024(SGSH)
PBG122486181(SGSH)
PTG102957138(SGSH)
PPAD109276815(SGSH)
AJU106981876(SGSH)
HHV120228151(SGSH)
BTA535442(SGSH)
BOM102274142(SGSH)
BIU109574273(SGSH)
BBUB102408571(SGSH)
CHX102175240(SGSH)
OAS101121184(SGSH)
ODA120866841(SGSH)
CCAD122438135(SGSH)
SSC100737146(SGSH)
CFR102511664(SGSH)
CBAI105065580(SGSH)
CDK105106252(SGSH)
BACU102997141(SGSH)
LVE103089895(SGSH)
OOR101289415(SGSH)
DLE111182732(SGSH)
PCAD102979953(SGSH)
PSIU116746061(SGSH)
ECB100056499(SGSH)
EPZ103547325(SGSH)
EAI106845569(SGSH)
MYB102239046(SGSH)
MYD102753251(SGSH)
MMYO118671232(SGSH)
MNA107532059(SGSH)
PKL118704505(SGSH)
HAI109383662(SGSH)
DRO112298704(SGSH)
SHON118999437(SGSH)
AJM119058533(SGSH)
PDIC114503187(SGSH)
PHAS123816840(SGSH)
MMF118634013(SGSH)
RFQ117013313(SGSH)
PALE102893583(SGSH)
PGIG120600100(SGSH)
PVP105305235(SGSH)
RAY107510086(SGSH)
MJV108410242(SGSH)
TOD119232100(SGSH)
SARA101545545(SGSH)
LAV100658885(SGSH)
TMU101346127
DNM101443773(SGSH)
MDO100030803(SGSH)
GAS123244254(SGSH)
SHR100932279(SGSH)
PCW110218200(SGSH)
OAA100079215(SGSH)
GGA422081(SGSH)
PCOC116232528(SGSH)
MGP100549132(SGSH)
CJO107322087(SGSH)
NMEL110407409(SGSH)
ACYG106046739(SGSH)
AFUL116496701(SGSH)
TGU100230664(SGSH)
LSR110472432(SGSH)
SCAN103819936(SGSH)
PMOA120505556(SGSH)
OTC121338448(SGSH) 121346566
PRUF121363415(SGSH)
GFR102037178(SGSH)
FAB101812983(SGSH)
PHI102110099(SGSH)
PMAJ107212385(SGSH)
CCAE111944975
CCW104698239(SGSH)
ETL114068232(SGSH)
FPG101918825(SGSH)
FCH102050903(SGSH)
CLV102090183(SGSH)
EGZ104130619(SGSH)
NNI104014329(SGSH)
TALA116963611(SGSH)
PADL103917442(SGSH)
ACHC115341963(SGSH)
AAM106484733 106485998(SGSH)
AROW112973728(SGSH)
NPD112945335(SGSH)
DNE112990910(SGSH)
ASN102382451(SGSH)
AMJ102576386(SGSH)
CPOO109314896(SGSH)
GGN109296262(SGSH)
PSS102460593(SGSH)
CMY102940151(SGSH)
CPIC101954045(SGSH)
TST117887342(SGSH)
CABI116834881(SGSH)
MRV120383168(SGSH)
ACS100561423(sgsh)
PVT110090123(SGSH)
SUND121921400(SGSH)
PBI103064462(SGSH)
PMUR107288798(SGSH)
TSR106541220(SGSH)
PGUT117662998(SGSH)
VKO123036910(SGSH)
PMUA114588986(SGSH)
ZVI118079703(SGSH)
GJA107119861(SGSH)
XLA495504(sgsh.L)
XTR100145064(sgsh)
NPR108792969(SGSH)
RTEM120919573(SGSH)
BBUF121003353(SGSH)
BGAR122942624(SGSH)
DRE563849(sgsh)
SRX107756031
SANH107663661 107704414
SGH107586947(sgsh) 107593085
CCAR109047860
CAUA113064755(sgsh)
IPU108259505(sgsh)
PHYP113524254(sgsh)
SMEO124380025(sgsh)
AMEX103028698(sgsh)
EEE113585727(sgsh)
TRU101072409(sgsh)
TNGGSTEN00026257G001
LCO104930251(sgsh)
NCC104950013(sgsh)
CGOB115007890(sgsh)
ELY117254894(sgsh)
PLEP121941785(sgsh)
SLUC116042645(sgsh)
ECRA117959060(sgsh)
PFLV114573952(sgsh)
GAT120824777(sgsh)
PPUG119218210(sgsh)
MSAM119899535 119917805
CUD121508336(sgsh)
MZE101463965(sgsh)
ONL100699960(sgsh)
OAU116330798(sgsh)
OLA101155495(sgsh)
OML112137359(sgsh)
XMA102222374(sgsh)
XCO114144623(sgsh)
XHE116719941(sgsh)
PRET103465890(sgsh)
PFOR103150518 103150523
PLAI106960591(sgsh)
PMEI106917554(sgsh)
GAF122829630(sgsh)
CVG107103621(sgsh)
CTUL119783307(sgsh)
NFU107392187(sgsh)
KMR108236263(sgsh)
ALIM106534568(sgsh)
NWH119422818(sgsh)
AOCE111571894(sgsh)
CSEM103383950(sgsh) 103383953
POV109627331(sgsh)
SSEN122771152(sgsh)
HHIP117768808(sgsh)
LCF108875653(sgsh)
SDU111229298(sgsh)
SLAL111666628(sgsh)
XGL120800103(sgsh)
HCQ109527474(sgsh)
BPEC110165214(sgsh) 110165216
MALB109957842(sgsh)
SASA100195283(sphm) 106564344(SPHM)
OTW112237038(sgsh) 112242248
OMY110485478 110485486
OGO124002725(sgsh)
ONE115128110(sgsh)
SALP112078376(sgsh)
SNH120018796 120018827
ELS105012037(sgsh)
SFM108930233(sgsh)
PKI111846603(sgsh)
AANG118221422(sgsh)
LOC102687031(sgsh)
PSPA121296638
ARUT117424259
LCM102349697(SGSH)
CMK103175583(sgsh)
BFO118428791
BBEL109461930
CIN113474074
SCLV120342154
SPU115923568 589739 592189
APLC110980262 110989034
SKO100375751 100375900 100378056
DMEDmel_CG14291(Sgsh)
DER6553879
DSE6613707
DSIDsimw501_GD20144(Dsim_GD20144)
DYADyak_GE25163
DAN6505660
DSR110186654
DPODpse_GA12883
DPE113565741
DMN108157467
DWI6649855
DGR6563634
DMODmoj_GI24623
DAZ108621019
DNV108659592
DHE111604223
DVI6635108
CCAT101455311
BOD106616035
MDE101887821
SCAC106082956
LCQ111690399
AGAAgaP_AGAP004205
ACOZ120949141
AARA120893958
AAG5573339
AALB109413692
CQUCpipJ_CPIJ010201
CPII120426771
CNS116343686
AME550884
ACER108000124
ALAB122713638
BIM100747363
BBIF117213718
BVK117231385
BVAN117156570
BTER100645767
BPYO122572551
CCAL108625086
OBB114875231
MGEN117225641
NMEA116425802
CGIG122396452
SOC105205194
MPHA105835776
AEC105152566
ACEP105621840
PBAR105426128
VEM105566120
HST105188180
CFO105249090
FEX115235971
LHU105667524
PGC109858431
OBO105279540
PCF106793887
PFUC122526547
VPS122634396
NVI100119668
CSOL105362363
TPRE106657700
MDL103574073
CGLO123274866
FAS105273628
DAM107038722
AGIF122857702
CCIN107264631
TCA659261
DPA109541348
SOY115884687
ATD109594649
AGB108907276
NVL108561271
APLN108737232
PPYR116177611
OTU111426415
BMOR101737423
BMAN114244627
MSEX115448751
DPLKGM_209387
BANY112051443
PMAC106721422
PXU106118955
PRAP111002361
ZCE119832298
HAW110381460
TNL113508096
OFU114357940
PXY105387712
BTAB109035959
CLEC106663397
HHAL106686440
NLU111058669
PHUPhum_PHUM328420
FOC113209166
ZNE110832827
CSEC111862267
DPXDAPPUDRAFT_327208
DMK116921354
PVM113823251
PJA122256830
HAME121866386
PCLA123754274
PTRU123513704
HAZT108683171
ISCIscW_ISCW005581
DSV119453309
RSAN119400169
RMP119180246 119180396
CSCU111635290
PTEP107452892
SDM118181979
LGILOTGIDRAFT_175173 LOTGIDRAFT_228392 LOTGIDRAFT_230682
PCAN112559397 112561320 112561321
BGT106055120 106061023
GAE121368468 121378994
HRF124113807 124119286 124134918 124151766 124152992
HRJ124263045 124263062 124266384 124266393 124269809 124284129
CRG105339838
MYI110448223
PMAX117334419
MMER123524313 123564697
OBI106867433
OSN115218184
LAK106157597 106165551
NVE5506258
EPA110255094
ATEN116299135
ADF107348323
AMIL114964843
PDAM113674502 113677127
SPIS111327167 111338001
DGT114527829
XEN124439540
AQU100638186
TTTTHITE_2045416
TMNUCRPA7_1159
SSCKSPSK_06264
FGRFGSG_08040
FPUFPSE_02331
FVRFVEG_05696
FOXFOXG_02508
NHENECHADRAFT_44955
PLJVFPFJ_04760
CFJCFIO01_10451
ELAUCREL1_3603
GLZGLAREA_03587
ANGANI_1_1460064(An07g01010)
ALUCAKAW2_12036A
APUUAPUU_31230S
PDPPDIP_19570
TRGTRUGW13939_08462 TRUGW13939_10963
ZTRMYCGRDRAFT_101694
PFJMYCFIDRAFT_173612
BCOMBAUCODRAFT_313725
PWAPecwa_0762
PPARA8F97_15150
PECW5S_0662
PWSA7983_11180
PPOABJK05_19705
PPUJE2566_03275
DJICH75_16055
VGABSQ33_06050
PGBH744_1c0228
CPSCPS_2367
COLWA3Q33_17925
PATPatl_1841 Patl_2695
PCARPC2016_3967
ALRDS731_21240
GAGGlaag_1596 Glaag_1823
PMESFX988_04194
CATEC2869_00035 C2869_00040 C2869_07625 C2869_07645 C2869_07735 C2869_07740
MPSYCEK71_01495 CEK71_16615
GAIIMCC3135_05985
CBWRR42_s1950
RPODE0E05_05990
DEIC4375_10445
MAADAZF01_13315
MMEDMame_02677
MLUTJET14_14470
LAGGB0E33_18735
MALGMALG_04863
TPROGa0080559_TMP403
NPNJI59_19680
SPHKSKP52_01925
SPHXE5675_04650
SSANNX02_06240 NX02_06935
SPANAWL63_16035
SKRBRX40_11940
SPHCCVN68_02925
SPHFDM480_12050
SPAPH3Z74_11965
SARIH5J25_10400
SYBTZ53_06530
SHYDCJD35_07970
SUFLFIL70_22375
SBARH5V43_18435
SPPHKFK14_06730
PALGHFP57_06670
ANHA6F65_00911(betC_1)
ADOA6F68_00094(betC_1) A6F68_00808(betC_4)
ERKCD351_04850
PORLBG023_112795
GOHB932_3172
GALA0U94_09925
BCIRC2I06_16280
MEKUHUW50_15035
PSABPSAB_07115
PBJVN24_13780
PNPIJ22_32750
POWIJ21_32550
PSWUSY83_13335
PALBEJC50_06600
PSOPKP014_10835
AFXJZ786_10330 JZ786_24435
PMARB0X71_18120
PLAYDNR44_000415
EAVEH197_05945
VGUHYG85_04835
VPYHZI73_08020 HZI73_24405
ARRARUE_c37330(sGSH)
ARMART_2646
ARNCGK93_20205
BRXBH708_02555
BRZCFK38_10610
HALTIM660_01985 IM660_03820 IM660_19195 IM660_19210
MIKFOE78_00785
NOWGBF35_30865
PLKCIK06_18425
ATLAthai_37910
RXYRxyl_2349
GLPGlo7428_0170
KBSEPA93_34470
TTRTter_0440
DDRDeide_3p00960
TRATrad_1264 Trad_2297
VBHCMV30_18690
CAACaka_0430
ROOG5S37_08250 G5S37_18470 G5S37_18490 G5S37_20290 G5S37_21355
LUOHHL09_01150 HHL09_01160 HHL09_03140
VBAIMCC26134_05060 IMCC26134_05160
VBSEGM51_05450 EGM51_07810 EGM51_07815 EGM51_07830
RBARB10117(atsG) RB2135 RB2663 RB2732 RB5294 RB5295 RB5383 RB724
PSLPsta_1456 Psta_4506 Psta_4602
PIRVN12_01650(atsA_4) VN12_04990(betC_1) VN12_10510(betC_2) VN12_12025(atsA_16) VN12_18880(betC_3)
RULUC8_02330(atsA_5) UC8_11520 UC8_11630(betC_3) UC8_17520 UC8_19110(atsA_23) UC8_20540(betC_5) UC8_37470(betC_9)
MFFMFFC18_27000(atsA_10) MFFC18_42390 MFFC18_42400(atsA_24) MFFC18_50970
ROLCA51_22140(atsA_16) CA51_25410 CA51_27620 CA51_30230 CA51_48820
AHELQ31a_03900(betC_1) Q31a_08450(atsA_15) Q31a_11370 Q31a_18280 Q31a_29060(atsA_33) Q31a_30260 Q31a_34430(betC_9) Q31a_38730 Q31a_40480 Q31a_46370
LCREPla8534_04160(betC_2) Pla8534_15480(betC_6) Pla8534_18270(atsA_22) Pla8534_27310(atsA_28) Pla8534_40150 Pla8534_51610(atsA_43) Pla8534_65770 Pla8534_69000(betC_15) Pla8534_69950
AAGGETAA8_02110(betC_1) ETAA8_15390(atsA_10) ETAA8_15400(betC_2) ETAA8_19580 ETAA8_36830 ETAA8_41420 ETAA8_56780(betC_9)
BVOPan97_00490 Pan97_01900(betC_2) Pan97_05830(betC_6) Pan97_12050 Pan97_20210(betC_9) Pan97_29790
TTFTHTE_0818 THTE_2855 THTE_2871
LPAVPLANPX_0171 PLANPX_2453
AMUCPan181_07380 Pan181_08150 Pan181_22230(betC_1) Pan181_22430 Pan181_31250 Pan181_46220(betC_4)
PNDPla175_11100 Pla175_13520 Pla175_42150 Pla175_43350 Pla175_43950 Pla175_46360(betC_24) Pla175_49020
PLMPlim_0706 Plim_3398
PEHSpb1_14920 Spb1_41140
PBSPlabr_0172 Plabr_0423 Plabr_1706 Plabr_2856 Plabr_2917 Plabr_3296 Plabr_3372 Plabr_3444 Plabr_4329
PLSVT03_00585(betC_1) VT03_05165(atsA_4)
PLHVT85_12930(betC_2)
FMRFuma_01626 Fuma_02487 Fuma_04315(betC_10) Fuma_04354 Fuma_05021(betC_11) Fuma_05717(betC_13) Fuma_06003(betC_14) Fuma_06016
GMRGmarT_12620(atsA_6) GmarT_14400(atsA_8) GmarT_33210(atsA_17) GmarT_38040(betC_8) GmarT_46930 GmarT_53660 GmarT_56740(atsA_50) GmarT_58240(atsA_53)
GIMF1728_04795 F1728_07750 F1728_08425 F1728_15445 F1728_16165 F1728_17645 F1728_19975 F1728_21745 F1728_27205 F1728_29830
GPNPan110_12470(atsA_5) Pan110_13780(atsA_7) Pan110_31220(atsA_20) Pan110_36280(betC_7) Pan110_45400 Pan110_50760(betC_10) Pan110_54400 Pan110_57850(atsA_63) Pan110_59530(betC_15)
MRIMal4_01630(betC_1) Mal4_12070 Mal4_12150 Mal4_12840(betC_4) Mal4_14250(betC_5) Mal4_23570 Mal4_30750(betC_14) Mal4_34910(atsA_45) Mal4_46290(betC_19) Mal4_57020(atsA_64)
SDYNMal52_16600(atsA_13) Mal52_25700(atsA_21) Mal52_53080(atsA_30)
PLONPla110_15660(atsA_6) Pla110_19280(atsA_11)
TIMGMBLW1_16110
LRSPX52LOC_00277 PX52LOC_00805
ULIETAA1_23260 ETAA1_34860
IPAIsop_2942
SACISinac_3870 Sinac_4591
AGVOJF2_43630
PHMPSMK_05120 PSMK_07230 PSMK_17980
PBUL21SP3_01206(atsA_15) L21SP3_01315(betC_1) L21SP3_01596 L21SP3_01734 L21SP3_01735(atsA_22) L21SP3_01736(betC_4)
PBPSTSP1_00691(atsA_13) STSP1_00706(betC_1) STSP1_00707(betC_2) STSP1_00800 STSP1_00966 STSP1_01854(betC_6)
PBASSMSP2_00225(betC_1) SMSP2_00681 SMSP2_00846 SMSP2_01952
ALUSSTSP2_00081 STSP2_00809 STSP2_02510 STSP2_03125
HBSIPV69_03230 IPV69_06430 IPV69_06485 IPV69_17650 IPV69_20250 IPV69_21880 IPV69_23730
VBLL21SP4_00075 L21SP4_00139 L21SP4_00409(betC_2) L21SP4_00427(betC_3) L21SP4_00522 L21SP4_00944 L21SP4_01367 L21SP4_01486(atsA_23) L21SP4_02199(betC_9)
TSAAciPR4_1589
EDAGWR55_08450
SUSAcid_4006
PFERIRI77_07500
ABACLuPra_04148(betC_6)
FVAFV113G1_05860
FULC4N20_03360
FMOC4N19_06205
STRSterm_0122 Sterm_1723
GBAJ421_0703
BTHOBtheta7330_00192(betC_2) Btheta7330_00198(betC_3) Btheta7330_00606
BHLBache_1609
BXYBXY_28060
BOABovatus_03639(atsA_13)
BCELBcellWH2_02345 BcellWH2_03659(atsA_14)
BCAEA4V03_17470
BHFC3V43_00310
BISDXK01_001285 DXK01_002220 DXK01_002225 DXK01_010260
BUNBun01g_05000
PETPEIBARAKI_4978 PEIBARAKI_6963
PSACPSM36_3069 PSM36_3221
COPRCop2CBH44_22980 Cop2CBH44_29090
AFDAlfi_3056
ASHAL1_31000
DORIFH5T_02580
DRCG0Q07_00735 G0Q07_19645
MCOSGM418_02465 GM418_02470 GM418_02475 GM418_07285 GM418_07465 GM418_09915 GM418_11535 GM418_11710 GM418_14225 GM418_15445 GM418_17600 GM418_17605 GM418_18715 GM418_24890 GM418_25795 GM418_27215 GM418_27355 GM418_28185 GM418_28955
ASXCDL62_09660
MBASALGA_0688 ALGA_0702 ALGA_2828
RBARAWN76_001870 AWN76_016890
CPICpin_4597
CHITFW415_13160 FW415_20895 FW415_21995
NSONIASO_00020 NIASO_15705
NIAA8C56_05395 A8C56_17625 A8C56_23710
AGIFSB73_00200 FSB73_00290
ARACE0W69_005405
LACSH4075_16675
HHYHalhy_3559 Halhy_6272 Halhy_6811
PHEPhep_2826
PEJFYC62_04250
PROEH9L23_14705
PSNPedsa_1812 Pedsa_3410
SHGSph21_0941 Sph21_4315
SPHEGFH32_04275 GFH32_04280 GFH32_04285
SDJNCTC13534_01305(betC_1)
MMABHQ865_23640
AGDFRZ59_01500 FRZ59_03220 FRZ59_08485 FRZ59_17285
OLIFKG96_01695 FKG96_19045
SBXCA265_11140
CMRCycma_0174 Cycma_2434 Cycma_2900 Cycma_3594 Cycma_3824 Cycma_3882 Cycma_4678 Cycma_4679
CAMUCA2015_0153 CA2015_3467 CA2015_3755 CA2015_3833 CA2015_4489 CA2015_4490
EVIEchvi_2707 Echvi_3778 Echvi_4340
ESTDN752_02220 DN752_04805 DN752_05415 DN752_09260 DN752_23420 DN752_23550 DN752_23575
ECHIFKX85_12905 FKX85_17780 FKX85_20570
ALMAO498_05110
SLISlin_4179
SRDSD10_02790 SD10_05405
SMONAWR27_05505 AWR27_05510
SPIRCWM47_28675
SPIKEXU85_05960
SPIBG8759_22700 G8759_26635 G8759_34345
STAEHNV11_18650
RHOZGXP67_26495 GXP67_36175
DFEDfer_0798 Dfer_1780 Dfer_2520
RSIRunsl_2858 Runsl_3076
RUNDR864_10195 DR864_11535
RUPDTQ70_29180
ALSDJ013_05155 DJ013_17125 DJ013_19730
RUFTH63_11885 TH63_11915
FLMMY04_4241 MY04_4254 MY04_5139 MY04_5240 MY04_5252 MY04_5374 MY04_5390
FLLEI427_16570 EI427_17475 EI427_17495 EI427_21785
FYAKMW28_20790 KMW28_21330 KMW28_21400 KMW28_23455
FKAKM029_22985 KM029_24865
FBTD770_14455
FFAFFWV33_15070 FFWV33_15140 FFWV33_17960 FFWV33_18005
FNKE1750_17195 E1750_17310
RBIRB2501_00946 RB2501_10742
ZPRZPR_4386
FBCFB2170_14753 FB2170_15418
MARMYQ22_01925
MARTBTR34_02160
MARBCJ263_16545
MAREEJ994_10185
ZGAZOBELLIA_2192(sgsA2) ZOBELLIA_2196(sgsA3) ZOBELLIA_2201(sgsA4) ZOBELLIA_2210(sgsA5) ZOBELLIA_2216(sgsA6)
MUTGVT53_00880 GVT53_00965 GVT53_02525
SPONHME9304_00220 HME9304_00652 HME9304_00655
POLABXQ17_09800
PHALH9I45_05940
SZEAW14_08955 AW14_13325
AHZAPS56_05645 APS56_06655
WFUAXE80_06055 AXE80_08015 AXE80_08075 AXE80_10315
FOHFORMA_02040
SEONBWZ22_10260
AALGAREALGSMS7_00950 AREALGSMS7_01153 AREALGSMS7_02021 AREALGSMS7_03132 AREALGSMS7_03754
FEKC1H87_01625
TAJC1A40_12850
KANIMCC3317_46550
EMARD1013_02975 D1013_04560 D1013_08650 D1013_19235
GAAHX109_03015 HX109_07530 HX109_09165 HX109_11735 HX109_11750
HRRHZS55_03305
HPELHZS54_04255
HLTI7X12_08610
HARCHARCEL1_11715
HGIABY42_10390
HTUHtur_3375
HDABB347_16295
HSALJMJ58_11595
HAKZJ0X25_04550
NMGNmag_3825
HXAHalxa_0118 Halxa_3576
NGENatgr_0434
NOUNatoc_2250 Natoc_3654
SALIL593_00570
HLCCHINAEXTREME12275
NAJB1756_15685
NAGAArcMg_2639
NANAArc1_1065
NBGDV706_04720
 » show all
Reference
1  [PMID:5775690]
  Authors
Dietrich CP.
  Title
Enzymic degradation of heparin. A sulphamidase and a sulphoesterase from Flavobacterium heparinum.
  Journal
Biochem J 111:91-5 (1969)
DOI:10.1042/bj1110091
Reference
2  [PMID:6849981]
  Authors
Mahuran D, Clements P, Hopwood J.
  Title
A rapid four column purification of 2-deoxy-D-glucoside-2-sulphamate sulphohydrolase from human liver.
  Journal
Biochim Biophys Acta 757:359-65 (1983)
DOI:10.1016/0304-4165(83)90062-4
Other DBs
ExplorEnz - The Enzyme Database: 3.10.1.1
IUBMB Enzyme Nomenclature: 3.10.1.1
ExPASy - ENZYME nomenclature database: 3.10.1.1
BRENDA, the Enzyme Database: 3.10.1.1
CAS: 37289-41-1
LinkDB

KEGG   REACTION: R07814
Entry
R07814                      Reaction                               
Definition
G13036 + H2O <=> G13037 + Sulfate
Equation
Enzyme
Pathway
rn00531  Glycosaminoglycan degradation
rn01100  Metabolic pathways
Module
M00078  Heparan sulfate degradation
Orthology
K01565  N-sulfoglucosamine sulfohydrolase [EC:3.10.1.1]
LinkDB

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