KEGG ORTHOLOGY: K03193

ORTHOLOGY: K03193

Entry

K03193                      KO

Symbol

UST

Name

dermatan/chondrotin sulfate uronyl 2-O-sulfotransferase UST [EC:2.8.2.-]

Pathway

map00532

Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09107 Glycan biosynthesis and metabolism
   00532 Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate
    K03193  UST; dermatan/chondrotin sulfate uronyl 2-O-sulfotransferase UST
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01003 Glycosyltransferases
    K03193  UST; dermatan/chondrotin sulfate uronyl 2-O-sulfotransferase UST
Glycosyltransferases [BR:ko01003]
Unclassified
  Sulfotransferases
   K03193  UST; dermatan/chondrotin sulfate uronyl 2-O-sulfotransferase UST

Genes

HSA:	10090(UST)

PTR:	748624(UST)

PPS:	100993550(UST)

GGO:	101125822(UST)

PON:	100457816(UST)

PPYG:

129038733(UST)

NLE:	100597036(UST)

HMH:	116463095 116463124

SSYN:

129475001(UST)

MCC:	697355(UST)

MCF:	102120355(UST)

MTHB:

126952498

MNI:	105488996(UST)

CSAB:

103240172(UST)

CATY:

105588809(UST)

PANU:

100999189(UST)

TGE:	112623552(UST)

MLEU:

105528782(UST)

RRO:	104676274(UST)

RBB:	108536659(UST)

TFN:	117097303(UST)

PTEH:

111523656(UST)

CANG:

105515558(UST)

CJC:	100413769(UST)

SBQ:	101031460(UST)

CIMI:

108287397(UST)

ANAN:

105717371(UST)

CSYR:

103253545(UST)

MMUR:

105858024(UST)

LCAT:

123633355(UST)

PCOQ:

105819333(UST)

OGA:	100956280(UST)

MMU:	338362(Ust)

MCAL:

110303687(Ust)

MPAH:

110338089(Ust)

RNO:	361450(Ust)

MCOC:

116097747(Ust)

ANU:	117700225(Ust)

MUN:	110554213(Ust)

CGE:	100760763(Ust)

MAUA:

101831815(Ust)

PROB:

127237653(Ust)

PLEU:

114686396(Ust)

MORG:

121466573(Ust)

MFOT:

126513321

AAMP:

119820875(Ust)

NGI:	103731933 103737027

HGL:	101699506(Ust)

CPOC:

100718472(Ust)

CCAN:

109696544(Ust)

DORD:

105993675(Ust)

DSP:	122105730(Ust)

PLOP:

125357387(Ust)

NCAR:

124988586

MMMA:

107152368(Ust)

OCU:

100343766

OPI:	101535935(UST)

TUP:	102492904(UST)

CFA:	476238(UST)

CLUD:

112644283(UST)

VVP:	112919508(UST)

VLG:	121484777(UST)

NPO:	129500818(UST)

AML:	100468590(UST)

UMR:	103666973(UST)

UAH:	113259539(UST)

UAR:	123797426(UST)

ELK:

111147596

LLV:

125102566

MPUF:

101683156(UST)

MNP:	132018228(UST)

MLK:	131833697(UST)

NVS:	122905578(UST)

ORO:	101369139(UST)

EJU:	114209188(UST)

ZCA:	113927141(UST)

MLX:	118001046(UST)

NSU:	110583195(UST)

LWW:

102745609

FCA:	101080970(UST)

PYU:	121013338(UST)

PCOO:

112862600(UST)

PBG:	122490076(UST)

PVIV:

125166383(UST)

LRUF:

124527925

PTG:	102963109(UST)

PPAD:

109252499(UST)

PUC:

125939154

AJU:

106987177

HHV:	120237566(UST)

BTA:	535975(UST)

BOM:	102278794(UST)

BIU:	109564025(UST)

BBUB:

102414339(UST)

BBIS:

105004833(UST)

CHX:	102168453(UST)

OAS:	101103732(UST)

BTAX:

128053314(UST)

ODA:	120862590(UST)

CCAD:

122434099(UST)

MBEZ:

129561307(UST)

SSC:	100738738(UST)

CFR:	102515784(UST)

CBAI:

105077448(UST)

CDK:	105100905(UST)

VPC:	102531658(UST)

BACU:

102998147(UST)

BMUS:

118905336(UST)

LVE:	103074608(UST)

OOR:	101284622(UST)

DLE:	111166805(UST)

PCAD:

102975654(UST)

PSIU:

116763722(UST)

NASI:

112401674(UST)

ECB:	100060503(UST)

EPZ:	103548738(UST)

EAI:	106837319(UST)

MYB:	102248414(UST)

MYD:	102770829(UST)

MMYO:

118659713(UST)

MLF:	102436866(UST)

MDT:	132236802(UST)

PKL:	118705292(UST)

EFUS:

103302358(UST)

MNA:	107545739(UST)

DRO:	112297110(UST)

SHON:

118978927(UST)

AJM:	119057885(UST)

PDIC:

114495199(UST)

PHAS:

123822035(UST)

MMF:	118621200(UST)

PPAM:

129067832(UST)

HAI:	109380899(UST)

RFQ:	117020349(UST)

PALE:

102899008(UST)

PGIG:

120589390(UST)

PVP:	105289503(UST)

RAY:	107518449(UST)

MJV:	108383490(UST)

TOD:	119252962(UST)

SARA:

101539593(UST)

SETR:

126029490(UST)

LAV:	100657586(UST)

TMU:

101355398

ETF:	101657813(UST)

DNM:	101411122(UST)

MDO:	100026835(UST)

GAS:	123243623(UST)

SHR:	100932805(UST)

AFZ:

127562311

PCW:	110208532(UST)

TVP:	118857412(UST)

OAA:	103167101(UST)

GGA:	768809(UST)

PCOC:

116241599(UST)

MGP:	100539083(UST)

CJO:	107311563(UST)

TPAI:

128080004(UST)

LMUT:

125688783(UST)

NMEL:

110395734(UST)

APLA:

101789997(UST)

ACYG:

106034267(UST)

CATA:

118244025(UST)

AFUL:

116487632(UST)

TGU:	100218364(UST)

LSR:	110468847(UST)

SCAN:

103818580(UST)

PMOA:

120501418(UST)

OTC:	121346061(UST)

PRUF:

121354823(UST)

GFR:	102033660(UST)

FAB:	101814215(UST)

OMA:	130251459(UST)

PHI:	102108977(UST)

PMAJ:

107202375(UST)

CCAE:

111926822(UST)

CCW:	104693803(UST)

CBRC:

103617068(UST)

ETL:	114059188(UST)

ZAB:	102069945(UST)

ZLE:	135445631(UST)

ACHL:

103798303(UST)

SVG:	106858497(UST)

MMEA:

130572352(UST)

HRT:	120750997(UST)

SATI:

136359216(UST)

FPG:	101915604(UST)

FCH:	102050593(UST)

NNT:	104408431(UST)

SHAB:

115613848(UST)

ACUN:

113478583(UST)

TALA:

104360093(UST)

ACHC:

115344977(UST)

HALD:

104310377(UST)

HLE:	104840747(UST)

AGEN:

126038504

GCL:

127014416

CSTI:

104553033(UST)

MNB:	103781107(UST)

BRHI:

104498400(UST)

EGZ:	104133560(UST)

NNI:	104013799(UST)

PCRI:

104038601(UST)

PADL:

103917051(UST)

AFOR:

103900775(UST)

GSTE:

104259403(UST)

CLV:	102089258(UST)

MUI:	104541229(UST)

PGUU:

104467948(UST)

CUCA:

104056933(UST)

TEO:	104378126(UST)

OHA:	104328709(UST)

CPEA:

104390806(UST)

CVF:	104284913(UST)

RTD:	128907178(UST)

AAM:	106486818(UST)

AROW:

112974646(UST)

NPD:	112951639(UST)

TGT:	104576532(UST)

DNE:	112983278(UST)

SCAM:

104151186(UST)

ASN:	102386713(UST)

AMJ:	102558345(UST)

CPOO:

109320132(UST)

GGN:	109304261(UST)

PSS:	102451162(UST)

CMY:	102942957(UST)

CCAY:

125634078(UST)

DCC:	119853195(UST)

CPIC:

101944672(UST)

TST:	117874856(UST)

CABI:

116819781(UST)

MRV:	120402362(UST)

ACS:	100554086(ust)

ASAO:

132761042(UST)

PVT:	110082319(UST)

SUND:

121919417(UST)

PBI:	103054312(UST)

PMUR:

107287408(UST)

CTIG:

120309541(UST)

TSR:	106540978(UST)

PGUT:

117666351(UST)

APRI:

131191602(UST)

PTEX:

113439525(UST)

NSS:	113411130(UST)

VKO:	123019873(UST)

PMUA:

114594234(UST)

PRAF:

128410641(UST)

ZVI:	118082026(UST)

HCG:	128343075(UST)

GJA:	107114114(UST)

STOW:

125428614(UST)

EMC:	129338445(UST)

XLA:	108717884(ust.S)

XTR:	100496425(ust)

NPR:	108789385(UST)

RTEM:

120937396(UST)

BBUF:

120998561(UST)

BGAR:

122935665(UST)

MUO:	115466653(UST)

GSH:	117357856(UST)

DRE:	100331876 557218(usta)

SRX:	107710410 107726493 107732646 107734075

SANH:

107653994 107693148 107693205 107696116

SGH:	107552018 107594136 107601186(ust) 107601503

CCAR:

109113121

CAUA:

113060867 113062823 113077884 113120781

CGIB:

127937997 127983441 128031797

PTET:

122324513 122325063(usta) 122325494 122362150

LROH:

127179867 127183419(usta)

OMC:	131522973 131526982(usta)

PPRM:

120480227 120494236(usta)

RKG:	130075511(usta) 130088971

MAMB:

125268355 125278088(usta)

CIDE:

127499199 127502627

CERY:

137006691 137019032(usta)

MASI:

127415963 127454803 127456710

TROS:

130559893 130566241(usta)

TDW:	130433888(usta) 130436706

MANU:

129417541 129429649(usta)

IPU:	108260361(usta)

IFU:	128620962(usta)

PHYP:

113528938(ust)

SMEO:

124401845(usta)

TFD:	113662390(usta)

TVC:	132855297(usta)

TRN:	134320530(usta) 134325708

AMEX:

103024245 103025326(usta)

CMAO:

118815889(usta) 118823288

EEE:	113578154 113580763(ust)

CHAR:

105895710 105901550(usta)

TRU:	101078402(ust)

TFS:	130515650(usta)

TNG:	GSTEN00023046G001

LCO:	104922006(ust)

NCC:	104944683(ust)

TBEN:

117493452(usta)

CGOB:

115003774(ust)

PGEO:

117440134(usta)

GACU:

117537542(usta)

EMAC:

134876938(usta)

ELY:	117270309(usta)

EFO:	125896660(usta)

PLEP:

121955943(usta)

SLUC:

116066288(usta)

ECRA:

117961495(usta)

ESP:	116706456(ust)

PFLV:

114572699(ust)

GAT:	120807662(usta)

PPUG:

119195147(usta)

AFB:	129107274(usta)

CLUM:

117727575(usta)

PSWI:

130202920(usta)

MSAM:

119908834(usta)

SCHU:

122862618(usta)

CUD:	121521060(usta)

ALAT:

119013072(usta)

ASTR:

137613581(usta)

MZE:	101487027(ust)

ONL:	100702820(ust)

OAU:	116310739(usta)

OLA:	101160703(ust)

OML:	112157739(usta)

CSAI:

133418431(usta)

XMA:	102218726(ust)

XCO:	114158810(ust)

XHE:	116734587(ust)

PRET:

103457534(ust)

PFOR:

103135069(ust) 103135269

PLAI:

106937518 106949015

PMEI:

106933451(ust)

GAF:	122825509(usta)

PPRL:

129351249 129352420(usta)

CVG:	107086025(ust)

CTUL:

119795941(usta)

GMU:	124881996(usta)

NFU:	107377561(ust)

KMR:	108240113(usta)

ALIM:

106519776(ust)

NWH:	119418220(usta)

AOCE:

111569941(ust)

MCEP:

124999083(ustA)

CSEM:

103381095(ust)

POV:	109636152(ust)

SSEN:

122783643(usta)

HHIP:

117758572(usta)

HSP:	118099461(usta)

PPLT:

128459806(usta)

SMAU:

118290531(usta)

LCF:	108880916(usta)

SDU:	111235428(ust)

SLAL:

111650590

XGL:	120789484(usta)

HCQ:	109528024(ust)

SSCV:

125990049(usta)

SBIA:

133496753(usta)

PEE:	133417275(usta)

PTAO:

133467956(usta)

BPEC:

110154998(ust)

MALB:

109954452(ust)

BSPL:

114849290(usta)

SJO:	128377629(usta)

SASA:

106571811(ust) 106607986

STRU:

115174444 115177667

OTW:	112217779 112232981(usta)

OMY:	110522377 110529900(usta)

OGO:	123991030 123995248

ONE:	115108038 115139281

OKI:	109866214 109901002

OKE:	118371917 118398373

SALP:

111954545(ust) 112070222

SNH:	120019079 120024428(usta)

CCLU:

121548770 121552947

ELS:	105006964(ust)

SFM:	108921090 108941892

PKI:	111856314(ust) 111857981

AANG:

118230675(usta) 118233950

LOC:	102686655(ust)

PSPA:

121316945(usta)

ARUT:

117410964(usta)

PSEX:

120525342(usta)

LCM:

102353146

CMK:	103179283(usta)

RTP:	109916268(usta)

CPLA:

122553036(usta)

HOC:	132819501(usta)

LERI:

129699347(usta)

PMRN:

116953023(UST)

LRJ:	133353635(UST)

BFO:	118413369 118419121 118419122 118419123 118419124 118419412 118422647

BBEL:

109467828 109471497 109472790

CIN:	100177245 100186176 100187278 101241979 101242428 108951008

SCLV:

120326962 120327215 120328811 120329596 120329719 120329815 120329817 120330233 120330234 120332360 120340334 120341322 120342805 120345970 120346115 120346124 120346450 120346621 120348687

SPU:	100891657 589722 593546

LPIC:

APLC:

ARUN:

AJC:

SKO:	100313533(UST) 100370491 100370639 100371420 100373487 100373780 100375447 100375741 100376140 100376600 100376750 100377201

NVE:

EPA:

ATEN:

ADF:

AMIL:

PDAM:

SPIS:

DGT:

XEN:

Reference

PMID:10187838

Authors

Kobayashi M, Sugumaran G, Liu J, Shworak NW, Silbert JE, Rosenberg RD

Title

Molecular cloning and characterization of a human uronyl 2-sulfotransferase that sulfates iduronyl and glucuronyl residues in dermatan/chondroitin sulfate.

Journal

J Biol Chem 274:10474-80 (1999)
DOI:10.1074/jbc.274.15.10474

Sequence

[hsa:10090]

LinkDB

DBGET integrated database retrieval system