KEGG ORTHOLOGY: K04138

ORTHOLOGY: K04138

Entry

K04138                      KO

Symbol

ADRA2A

Name

adrenergic receptor alpha-2A

Pathway

map04022

cGMP-PKG signaling pathway

map04080

Neuroactive ligand-receptor interaction

Disease

H00420

Familial partial lipodystrophy

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04022 cGMP-PKG signaling pathway
    K04138  ADRA2A; adrenergic receptor alpha-2A
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    K04138  ADRA2A; adrenergic receptor alpha-2A
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors
    K04138  ADRA2A; adrenergic receptor alpha-2A
G protein-coupled receptors [BR:ko04030]
Rhodopsin family
  Biogenic amine
   Adrenaline
    K04138  ADRA2A; adrenergic receptor alpha-2A

Other DBs

GO:

0004938

Genes

HSA:	150(ADRA2A)

PTR:	466201(ADRA2A)

PPS:	100977068(ADRA2A)

GGO:	101137632(ADRA2A)

PON:	100459426(ADRA2A)

PPYG:

129006649(ADRA2A)

NLE:	100586093(ADRA2A)

HMH:	116478543(ADRA2A)

SSYN:

129466155(ADRA2A)

MCC:	695684(ADRA2A)

MCF:	102140075(ADRA2A)

MTHB:

126962832

MNI:	105466699(ADRA2A)

CSAB:

103216513(ADRA2A)

CATY:

105577899(ADRA2A)

PANU:

101022127(ADRA2A)

TGE:	112631627(ADRA2A)

MLEU:

105530168(ADRA2A)

RRO:	104667775(ADRA2A)

RBB:	108538806(ADRA2A)

TFN:	117066959(ADRA2A)

PTEH:

111538895(ADRA2A)

CJC:	103796811(ADRA2A)

SBQ:	101039216(ADRA2A)

CIMI:

108283359(ADRA2A)

ANAN:

105715789(ADRA2A)

CSYR:

103257221(ADRA2A)

MMUR:

105874992(ADRA2A)

LCAT:

123649614(ADRA2A)

PCOQ:

105825989(ADRA2A)

OGA:	100945880(ADRA2A)

MMU:	11551(Adra2a)

MCAL:

110285932(Adra2a)

MPAH:

110323161(Adra2a)

RNO:	25083(Adra2a)

MCOC:

116104006(Adra2a)

ANU:	117702593(Adra2a)

MUN:	110555627 132646016(Adra2a)

CGE:	100768369(Adra2a)

MAUA:

101836935(Adra2a)

PROB:

127233381(Adra2a)

PLEU:

114697053(Adra2a)

MORG:

121454408(Adra2a)

MFOT:

126506174

AAMP:

119821922(Adra2a)

NGI:	103744368(Adra2a)

HGL:	101723298(Adra2a)

CPOC:

100135475(Adra2a)

CCAN:

109691509(Adra2a)

DORD:

105986607(Adra2a)

DSP:	122116023(Adra2a)

PLOP:

125342700(Adra2a)

NCAR:

124984932

MMMA:

107149966(Adra2a)

OCU:	100009424(ADRA2A)

OPI:	101527118(ADRA2A)

TUP:	102480728(ADRA2A)

GVR:	103587673(ADRA2A)

CFA:	486888(ADRA2A)

CLUD:

112672332(ADRA2A)

VVP:	112914346(ADRA2A)

VLG:	121485554(ADRA2A)

NPO:	129493532(ADRA2A)

AML:	100474011(ADRA2A)

UMR:

103659210

UAH:	113251931(ADRA2A)

UAR:	123795960(ADRA2A)

ELK:

111144907

LLV:

125085114

MPUF:

101677041(ADRA2A)

MNP:	132016779(ADRA2A)

MLK:	131830693(ADRA2A)

NVS:	122901112(ADRA2A)

ORO:	101375317(ADRA2A)

EJU:	114200028(ADRA2A)

ZCA:	113923893(ADRA2A)

MLX:	118026208(ADRA2A)

NSU:	110589349(ADRA2A)

LWW:	102727516(ADRA2A)

FCA:	664736(ADRA2A)

PYU:	121037225(ADRA2A)

PCOO:

112854290(ADRA2A)

PBG:	122493245(ADRA2A)

PVIV:

125148318(ADRA2A)

LRUF:

124506736

PTG:	102948732(ADRA2A)

PPAD:

109272897(ADRA2A)

PUC:

125932970

AJU:

106984750

HHV:	120244302(ADRA2A)

BTA:	282135(ADRA2A)

BOM:	106700799(ADRA2A)

BIU:	109553206(ADRA2A)

BBUB:

102415282(ADRA2A)

BBIS:

105002620(ADRA2A)

CHX:	102187024(ADRA2A)

OAS:	100170317(ADRA2A)

BTAX:

128067995(ADRA2A)

ODA:	120873629(ADRA2A)

CCAD:

122446360(ADRA2A)

MBEZ:

129555351(ADRA2A)

SSC:	399501(ADRA2A)

CFR:	102504908(ADRA2A)

CBAI:

105080802(ADRA2A)

CDK:	105091698(ADRA2A)

VPC:	102537355(ADRA2A)

BACU:

103002174(ADRA2A)

BMUS:

118882688(ADRA2A)

LVE:	103085955(ADRA2A)

OOR:	101270435(ADRA2A)

DLE:	111172309(ADRA2A)

PCAD:

102991709(ADRA2A)

PSIU:

116741630(ADRA2A)

NASI:

112406945(ADRA2A)

ECB:	100147119(ADRA2A)

EPZ:	103564806(ADRA2A)

EAI:	106837548(ADRA2A)

MYB:	102259526(ADRA2A)

MYD:	102773898(ADRA2A)

MMYO:

118669746(ADRA2A)

MLF:	102441195(ADRA2A)

MDT:	132214334(ADRA2A)

PKL:	118719466(ADRA2A)

EFUS:

103288662(ADRA2A)

MNA:	107536418(ADRA2A)

DRO:	112300451(ADRA2A)

SHON:

118999420(ADRA2A)

AJM:	119064040(ADRA2A)

PDIC:

114497226(ADRA2A)

PHAS:

123828835(ADRA2A)

MMF:	118632444(ADRA2A)

PPAM:

129077315(ADRA2A)

HAI:	109384879(ADRA2A)

RFQ:	117036332(ADRA2A)

PALE:

102881586(ADRA2A)

PGIG:

120609095(ADRA2A)

PVP:	105294544(ADRA2A)

RAY:	107511394(ADRA2A)

MJV:	108404142(ADRA2A)

TOD:	119233479(ADRA2A)

SARA:

101538542(ADRA2A)

SETR:

126033623(ADRA2A)

LAV:	100672320(ADRA2A)

TMU:

101343943

ETF:	101660340(ADRA2A)

DNM:	101447216(ADRA2A)

MDO:	100027878(ADRA2A)

GAS:	123236269(ADRA2A)

SHR:	100929353(ADRA2A)

AFZ:

127551581

PCW:	110209505(ADRA2A)

TVP:	118829088(ADRA2A)

OAA:	114817287(ADRA2A)

GGA:	428980(ADRA2A)

PCOC:

116231622(ADRA2A)

MGP:	104912010(ADRA2A)

CJO:	107316160(ADRA2A)

TPAI:

128077877(ADRA2A)

LMUT:

125694057(ADRA2A)

NMEL:

110400027(ADRA2A)

APLA:

101803955(ADRA2A)

ACYG:

136786285(ADRA2A)

CATA:

118248663(ADRA2A)

AFUL:

116491484(ADRA2A)

TGU:	100231407(ADRA2A)

LSR:	110468273(ADRA2A)

SCAN:

103813826(ADRA2A)

PMOA:

120502217(ADRA2A)

OTC:	121341860(ADRA2A)

PRUF:

121350216(ADRA2A)

GFR:	102033754(ADRA2A)

FAB:	101809602(ADRA2A)

OMA:	130254749(ADRA2A)

PHI:	102109587(ADRA2A)

PMAJ:

107206514(ADRA2A)

CCAE:

111931312(ADRA2A)

CCW:	104695286(ADRA2A)

CBRC:

103616288(ADRA2A)

ETL:	114058417(ADRA2A)

ZAB:	102064107(ADRA2A)

ZLE:	135449830(ADRA2A)

ACHL:

103807272(ADRA2A)

SVG:	106850863(ADRA2A)

MMEA:

130582103(ADRA2A)

HRT:	120755906(ADRA2A)

SATI:

136364031(ADRA2A)

FPG:	101913158(ADRA2A)

FCH:	102053594(ADRA2A)

CCRI:

104166765(ADRA2A)

NNT:	104405967(ADRA2A)

SHAB:

115608941(ADRA2A)

ACUN:

113481778(ADRA2A)

TALA:

104361597(ADRA2A)

ACHC:

115348534(ADRA2A)

HALD:

104314219(ADRA2A)

HLE:	104830069(ADRA2A)

AGEN:

126042751

GCL:

127017735

CSTI:

104557803(ADRA2A)

LDI:	104340202(ADRA2A)

MNB:	103778935(ADRA2A)

DPUB:

104307118(ADRA2A)

AVIT:

104275633(ADRA2A)

BRHI:

104500533(ADRA2A)

EGZ:	104130416(ADRA2A)

NNI:	104022330(ADRA2A)

PCRI:

104038123(ADRA2A)

PCAO:

104051855(ADRA2A)

PADL:

103918576(ADRA2A)

AFOR:

103897733(ADRA2A)

FGA:

104080705

GSTE:

104254326

CLV:	102090898(ADRA2A)

MUI:	104545513(ADRA2A)

PGUU:

104461449

PLET:

104615176

EHS:	104502699(ADRA2A)

CMAC:

104478196

CUCA:

104065659(ADRA2A)

TEO:	104383560(ADRA2A)

BREG:

104630319(ADRA2A)

OHA:	104336341(ADRA2A)

ACAR:

104532778

CPEA:

104397898(ADRA2A)

CVF:	104283392(ADRA2A)

RTD:	128911287(ADRA2A)

AAM:	106488367(ADRA2A)

AROW:

112968030(ADRA2A)

NPD:	112957196(ADRA2A)

TGT:	104570066(ADRA2A)

DNE:	112993640(ADRA2A)

SCAM:

104142438(ADRA2A)

ASN:	102376693(ADRA2A)

AMJ:	102576082(ADRA2A)

CPOO:

109324308(ADRA2A)

GGN:	109287191(ADRA2A)

PSS:	102463694(ADRA2A)

CMY:	102938232(ADRA2A)

CCAY:

125640354(ADRA2A)

DCC:	119859554(ADRA2A) 122455350

CPIC:

101932100(ADRA2A)

TST:	117880948(ADRA2A) 117882166

CABI:

116832672(ADRA2A) 116833289

MRV:	120369309(ADRA2A)

ACS:	100555911 100558331(adra2a)

ASAO:

132769058 132770952(ADRA2A)

PVT:	110071962(ADRA2A) 110077980

SUND:

121922403 121927351(ADRA2A)

PBI:	103052146 103065281

PMUR:

107289372(ADRA2A) 107291403

CTIG:

120304034 120313039(ADRA2A)

TSR:	106548186(ADRA2A) 106553232

PGUT:

117678706(ADRA2A) 117679814

APRI:

131193320 131201468(ADRA2A)

PTEX:

113439104(ADRA2A) 113454979

NSS:	113412042(ADRA2A) 113415807

VKO:	123027637(ADRA2A) 123034020

PMUA:

114591455 114597484(ADRA2A)

PRAF:

128408076 128414236(ADRA2A)

ZVI:	118081554 118093936(ADRA2A)

HCG:	128346413 128352395(ADRA2A)

GJA:	107106572(ADRA2A) 107111528

STOW:

125427671 125438583(ADRA2A)

EMC:	129327617 129332935(ADRA2A)

XLA:	108695995(adra2a.L) 108697300 108710968 108713236

XTR:	100493940 780304(adra2a)

NPR:	108791938(ADRA2A)

RTEM:

120932215 120946844(ADRA2A)

BBUF:

121004597(ADRA2A)

BGAR:

122926379 122940899 122941153

MUO:	115469955(ADRA2A) 115476142

GSH:	117351771 117358681(ADRA2A)

DRE:	266750(adra2a)

SRX:	107717662 107720367

SANH:

107667886 107682903

SGH:	107559550 107602669

CCAR:

109047386 109047390

CAUA:

113039866 113065077

CGIB:

127942652 127988252

PTET:

122327078(adra2a)

LROH:

127153130(adra2a)

OMC:	131530355(adra2a)

PPRM:

120495171(adra2a)

RKG:	130103513(adra2a)

MAMB:

125253583(adra2a)

CIDE:

127520547

CERY:

137029038(adra2a)

MASI:

127438364 127438950

TROS:

130548330(adra2a)

TDW:	130430765(adra2a)

MANU:

129454055(adra2a)

IPU:

108259429

IFU:	128603034(adra2a)

PHYP:

113547616(adra2a)

SMEO:

124380197(adra2a)

TFD:	113657097(adra2a)

TVC:	132839021(adra2a)

TRN:	134303837(adra2a)

AMEX:

103035996(adra2a)

CMAO:

118804657(adra2a)

EEE:	113580684(adra2a)

CHAR:

105903460(adra2a)

TRU:	101064972 115253333(adra2a)

TFS:	130527099(adra2a) 130533801

TNG:	GSTEN00020015G001 GSTEN00024947G001

LCO:	104922185(adra2a) 104929743

NCC:	104956646(adra2a) 104958200

TBEN:

117474693(adra2a) 117499879

CGOB:

115006358 115020324

PGEO:

117454597(adra2a) 117460145

GACU:

117560814 117561700(adra2a)

EMAC:

134858941 134864020(adra2a)

ELY:	117248723 117254906(adra2a)

EFO:	125886339(adra2a) 125903627

PLEP:

121942622(adra2a) 121954914

SLUC:

116042894(adra2a) 116055356

ECRA:

117960860 117961525(adra2a)

ESP:	116698395(adra2a) 116704980

PFLV:

114572209 114573023

GAT:	120820362 120825669(adra2a)

PPUG:

119214103 119218661(adra2a)

AFB:	129092345 129096273(adra2a)

CLUM:

117733800(adra2a) 117744186

PSWI:

130190724(adra2a) 130206789

MSAM:

119899409 119917485

SCHU:

122873772(adra2a) 122884132

CUD:	121508049(adra2a) 121511381

ALAT:

119028598(adra2a) 119033427

ASTR:

137600362(adra2a) 137603751

MZE:	101474890(adra2a) 101483007

ONL:	100701604 102078120(adra2a)

OAU:	116310591(adra2a) 116322213

OLA:	101164871(adra2a) 101170540

OML:	112137475(adra2a) 112161824

CSAI:

133444166(adra2a) 133463537

XMA:	102219330 102229866

XCO:	114138311 114143890(adra2a)

XHE:	116713485 116719322

PRET:

103466293(adra2a) 103476774

PFOR:

103133635 103148727(adra2a)

PLAI:

106947695 106959093(adra2a)

PMEI:

106914135 106916404(adra2a)

GAF:	122829760(adra2a) 122842536

PPRL:

129359818 129366959(adra2a)

CVG:

107083403

CTUL:

119787343(adra2a)

GMU:	124859459 124867760(adra2a)

NFU:	107390778(adra2a) 107395486

KMR:	108241454(adra2a) 108242785

ALIM:

106513335 106521089(adra2a)

NWH:	119422905(adra2a)

AOCE:

111566897 111581670(adra2a)

MCEP:

125000851(adra2a) 125018540

CSEM:

103384070(adra2a) 103387643

POV:	109627419(adra2a) 109633396

SSEN:

122770591(adra2a) 122782039

HHIP:

117769758(adra2a) 117775437

HSP:	118115296(adra2a) 118119022

PPLT:

128436671(adra2a) 128453577

SMAU:

118284279 118312181(adra2a)

LCF:	108885386 108897320

SDU:	111229325(adra2a) 111235304

SLAL:

111649551 111668514(adra2a)

XGL:	120796888 120799757(adra2a)

HCQ:	109510183 109519865(adra2a)

SSCV:

125968667 125978250

SBIA:

133506640(adra2a) 133510035

PEE:	133403922(adra2a) 133410074

PTAO:

133476262(adra2a) 133485690

BPEC:

110156978 110166217(adra2a)

MALB:

109960428 109972273

BSPL:

114868907(adra2a)

SJO:	128369648(adra2a) 128372876

SASA:

106564475 106577022 106590134 106607268

STRU:

115147380 115152645 115178424 115193729

OTW:	112236770(adra2a) 112251138 112253433

OMY:	110485625 110502482 110514401 110529196

OGO:	124015905(adra2a) 124037230 124040756

ONE:	115113212 115115437 115136333

OKI:	109876896(adra2a) 109888984 109898857 116355449

OKE:	118369916 118372626 118400103

SALP:

111951776 111978602 112072243

SNH:	120032814(adra2a) 120045892 120066950

CCLU:

121553767 121553912(adra2a) 121583134

ELS:	105012128(adra2a)

SFM:	108918846(adra2a)

PKI:	111848363(adra2a)

AANG:

118217781 118219806

LOC:	102689792(adra2a)

PSPA:

121321518 121325996

ARUT:

117415017(adra2a) 117418090

LCM:	102348663(ADRA2A)

CMK:	103185246(adra2a)

RTP:

109929369

CPLA:

122543111(adra2b) 122561356(adra2a)

HOC:	132826391(adra2a) 132836843

LERI:

129704075(adra2a) 129713187(adra2b)

BFO:	118405056 118421992 118432205

BBEL:

109462876 109463269 109464444 109475745 109479439 109480452 109486209

SPU:

100889385

LPIC:

129267599 129268755 129271121 129272968 129273020 129273399 129275721 129282915 129282917

ARUN:

MJU:

CCRN:

IEL:

DMK:

ESN:	126983354 126999766

LSM:

121129530

TCF:	131879317 131879676

PPOI:

RMP:

VDE:

VJA:

LPOL:

PMEO:

129581340 129585422 129585425 129586485 129589886 129592629

PVUL:

126809527 126815854 126824238 126829447

GAE:	121370159 121370160 121370162

HRF:	124110933 124111690 124113394 124118056 124127057 124149162 124149183 124149193

HRJ:	124272146 124285603 124285623

CRG:	105329972 105332775 105338949 109617690 117681845 117682859 117691380

CANU:

128156672 128156900 128161880 128166109 128170898 128173150 128178405 128180829 128181544 128184755

CVN:	111111179 111112876 111132072

OED:	125648135 125663890 125664652 125682317

MYI:

110446675

PMAX:

117316709 117317999 117330017 117336609 117339827 117343661 117345059

MCAF:

127733142

MMER:

123536094 123546934 123548494 123565449

RPHI:

132713554 132713559 132713913 132717517 132717518 132723681 132724468 132724469 132724470 132724688 132730989 132733320 132736356 132736378 132743150 132745009 132745545

DPOL:

127831498 127838512 127838513 127838514 127840023 127842652 127852491 127852501 127858239 127858240 127859784 127878451

OSN:	115217095 115217143 115217164 115217208 115217209 115217213 115217243 115217470

XEN:

124433330

HSY:	130623067 130654605

» show all

Reference

PMID:1353249

Authors

Link R, Daunt D, Barsh G, Chruscinski A, Kobilka B

Title

Cloning of two mouse genes encoding alpha 2-adrenergic receptor subtypes and identification of a single amino acid in the mouse alpha 2-C10 homolog responsible for an interspecies variation in antagonist binding.

Journal

Mol Pharmacol 42:16-27 (1992)

Sequence

[mmu:11551]

LinkDB

DBGET integrated database retrieval system