KEGG ORTHOLOGY: K04140

ORTHOLOGY: K04140

Entry

K04140                      KO

Symbol

ADRA2C

Name

adrenergic receptor alpha-2C

Pathway

map04022

cGMP-PKG signaling pathway

map04080

Neuroactive ligand-receptor interaction

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04022 cGMP-PKG signaling pathway
    K04140  ADRA2C; adrenergic receptor alpha-2C
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    K04140  ADRA2C; adrenergic receptor alpha-2C
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors
    K04140  ADRA2C; adrenergic receptor alpha-2C
G protein-coupled receptors [BR:ko04030]
Rhodopsin family
  Biogenic amine
   Adrenaline
    K04140  ADRA2C; adrenergic receptor alpha-2C

Other DBs

GO:

0004938

Genes

HSA:	152(ADRA2C)

PTR:	465178(ADRA2C)

PPS:	100993507(ADRA2C)

GGO:	101153693(ADRA2C)

PON:	100938399(ADRA2C)

NLE:	100591173(ADRA2C)

MCC:	719763(ADRA2C)

MCF:	102129584(ADRA2C)

CSAB:

103246439(ADRA2C)

CATY:

105585526(ADRA2C)

PANU:

100997498(ADRA2C)

TGE:	112624958(ADRA2C)

RRO:	104678965(ADRA2C)

RBB:

108525445

TFN:	117085080(ADRA2C)

PTEH:

111539101(ADRA2C)

MMUR:

105860246(ADRA2C)

OGA:	100964286(ADRA2C)

MMU:	11553(Adra2c)

MCAL:

110295362(Adra2c)

MPAH:

110330905(Adra2c)

RNO:	24175(Adra2c)

MCOC:

116069086(Adra2c)

MUN:	110562357(Adra2c)

CGE:	103161652(Adra2c)

PLEU:

114702047(Adra2c)

NGI:	103741158(Adra2c)

HGL:	101723218(Adra2c)

CPOC:

101787589(Adra2c)

CCAN:

109687429(Adra2c)

DORD:

105991275(Adra2c)

DSP:	122100678(Adra2c)

NCAR:

124994623

TUP:	102499472(ADRA2C)

CFA:	488793(ADRA2C)

VVP:	112922690(ADRA2C)

VLG:	121490069(ADRA2C)

AML:	100467814(ADRA2C)

UAH:	113245678(ADRA2C)

UAR:	123775565(ADRA2C)

ELK:

111149310

LLV:

125093497

ORO:	101373984(ADRA2C)

EJU:	114198629(ADRA2C)

ZCA:	113924836(ADRA2C)

FCA:	101087990(ADRA2C)

PBG:	122479099(ADRA2C)

PTG:

107179003

PPAD:

109269734(ADRA2C)

AJU:	106978827(ADRA2C)

HHV:	120231815(ADRA2C)

BTA:	407139(ADRA2C)

BOM:	102285813(ADRA2C)

BBUB:

102391525(ADRA2C)

CHX:	102181288(ADRA2C)

OAS:	100170319(ADRA2C)

ODA:	120861810(ADRA2C)

CCAD:

122428358(ADRA2C)

SSC:	733706(ADRA2C)

CFR:	102520676(ADRA2C)

CBAI:

105072595(ADRA2C)

CDK:	105103347(ADRA2C)

VPC:	102538622(ADRA2C)

BACU:

103008893(ADRA2C)

LVE:	103074700(ADRA2C)

OOR:	101288539(ADRA2C)

DLE:	111164863(ADRA2C)

PCAD:

112063759(ADRA2C)

PSIU:

116753844(ADRA2C)

ECB:	111772982(ADRA2C)

EAI:	106840085(ADRA2C)

MYB:	102249134(ADRA2C)

MYD:	102767191(ADRA2C)

MMYO:

118666073(ADRA2C)

MNA:	107524104(ADRA2C)

PKL:	118707179(ADRA2C)

DRO:	112316673(ADRA2C)

SHON:

118987405(ADRA2C)

AJM:	119035536(ADRA2C)

PDIC:

114489956(ADRA2C)

PHAS:

123815656(ADRA2C)

MMF:	118616503(ADRA2C)

RFQ:	117021966(ADRA2C)

PALE:

102895430(ADRA2C)

PGIG:

120582736(ADRA2C)

PVP:	105301231(ADRA2C)

RAY:	107499758(ADRA2C)

MJV:

108397478

TOD:	119260859(ADRA2C)

LAV:	100668918(ADRA2C)

MDO:	100020740(ADRA2C)

GAS:	123251637(ADRA2C)

SHR:	100927538(ADRA2C)

PCW:	110212274(ADRA2C)

OAA:	100090717(ADRA2C)

GGA:	427631(ADRA2BL2) 428799(ADRA2C)

PCOC:

116225768(ADRA2C) 116231902

MGP:	100550610 104909214(ADRA2C)

CJO:	107314070(ADRA2C) 107320469

NMEL:

110398809(ADRA2C) 110405283

APLA:

101790023(ADRA2C) 113845158

ACYG:

106033335(ADRA2C)

AFUL:

116488621(ADRA2C) 116494779

TGU:	101232953 101233463(ADRA2C)

LSR:	110470815 110481882(ADRA2C)

SCAN:

103817516 103826124 115485332

PMOA:

120498598 120511618

OTC:	121332523 121335207(ADRA2C)

PRUF:

121349093(ADRA2C) 121361350

GFR:	102039660(ADRA2C)

FAB:	101809146 101811765(ADRA2C)

PHI:	102102017 102111432(ADRA2C)

PMAJ:

107203559(ADRA2C) 107210518

CCAE:

111928227(ADRA2C)

CCW:	104690916(ADRA2C)

ETL:	114061213(ADRA2C) 114066275

ZAB:	102071646(ADRA2C)

FPG:	101915995 101919690(ADRA2C)

FCH:	102053781(ADRA2C) 102054211

CLV:	102097195(ADRA2C)

EGZ:	104130208(ADRA2C)

NNI:	104018051(ADRA2C) 104019003

ACUN:

113479387(ADRA2C) 113485271

TALA:

104356590(ADRA2C) 116964756

PADL:

103920994(ADRA2C)

ACHC:

115334141 115346424(ADRA2C)

AAM:	106498672(ADRA2C)

AROW:

112964823 112974585(ADRA2C)

NPD:	112943057(ADRA2C)

DNE:	112996516(ADRA2C) 112996889

ASN:	102375154(ADRA2C)

AMJ:	102568542(ADRA2C)

CPOO:

109321809(ADRA2C)

GGN:	109304122(ADRA2C)

PSS:	102447937(ADRA2C)

CMY:	102937639(ADRA2C)

CPIC:

101934570(ADRA2C) 101952800

TST:	117878158(ADRA2C)

CABI:

116829689(ADRA2C)

MRV:	120405673(ADRA2C)

PVT:	110069786 110077980

SUND:

121918421

VKO:	123017109(ADRA2C)

PMUA:

114604723(ADRA2C)

ZVI:	118084204(ADRA2C)

GJA:	107112872(ADRA2C)

XLA:	108697938(adra2c.L) 108705869(adra2c.S)

XTR:	100145449(adra2c)

NPR:	108783754 108785823(ADRA2C)

RTEM:

120924406(ADRA2C)

BBUF:

120991825(ADRA2C)

BGAR:

122927844(ADRA2C)

DRE:	266752(adra2c) 266754(adra2da) 266755(adra2db)

SRX:	107712015 107715166 107749936 107749943 107752971 107756793 107756796 107757419

SANH:

107667592 107671617 107674202 107676165 107678652 107689214

SGH:	107552592 107556512 107556841 107566213 107571248 107590063

CCAR:

109045572 109046092 109071900 109081305 109088051 109088966

CAUA:

113039177 113047823 113063998 113075930 113078796 113080256 113097539

PPRM:

120465343(adra2da) 120492215(adra2c) 120494482(adra2db)

IPU:	108260662 108262932(adra2c) 108275442(adra2da) 108278623(adra2db)

PHYP:

113529498 113541651 113544082(adra2c) 113545716

SMEO:

124381556 124392960(adra2da) 124395471(adra2c) 124398029(adra2db)

TFD:	113635531 113642385(adra2c) 113646951(adra2db) 113654831(adra2da)

AMEX:

103025929 103033245 103042284

EEE:	113571287 113581745 113588338 113589940

TRU:	101069073 101074073 101078477 101078692

TNG:	GSTEN00006408G001 GSTEN00019239G001 GSTEN00022631G001

LCO:	104921951 104923970 104927068 104927241

NCC:	104941496 104946199 104952645(adra2c) 104953545

CGOB:

115006489 115006505 115009953 115015145 115023722

ELY:	117252436 117254990(adra2c) 117260634(adra2db) 117272884

PLEP:

121942481(adra2c) 121944545 121948429(adra2db) 121962330

SLUC:

116039692(adra2c) 116049034 116064328(adra2db) 116067281

ECRA:

117934971 117938832 117951587(adra2db) 117953723(adra2c)

PFLV:

114546115(adra2c) 114555554 114562898 114572862

GAT:	120812681 120818112(adra2db) 120823039 120824979(adra2c)

PPUG:

119196170 119210024(adra2db) 119217728(adra2c) 119221660

MSAM:

119888593(adra2db) 119890270 119899660(adra2c) 119911751

CUD:	121504097(adra2c) 121513215 121515974(adra2db)

MZE:	101472695 101474048 101479598 101486679

ONL:	100691231(adra2c) 100708556 100712311

OAU:	116310378 116323945 116328588(adra2c) 116329093(adra2db)

OLA:	101160174 101161340(adra2c) 101164629 101169521

OML:	112141982 112145518 112153018(adra2db) 112155680

XMA:	102221126 102226842 102235708 102236027

XCO:	114138644 114143551 114143858 114156795(adra2c)

XHE:	116714922 116719269 116720793 116732046

PRET:

103462980 103464341 103471265 103480445

PFOR:

103132190 103132197 103135531 103137486 103155222

PLAI:

106937344 106945756 106949366 106951016

PMEI:

106905564 106920867 106924559 106927598 106930928(adra2c)

GAF:	122819974 122824648 122830109(adra2c) 122837137(adra2db)

CVG:	107091080 107093758(adra2c) 107094989 107099081

CTUL:

119777897(adra2db) 119780571 119783403 119797989(adra2c)

GMU:	124859920(adra2db) 124866678 124868696(adra2c) 124880946

NFU:	107373463 107375821 107377377 107393278

KMR:	108236301(adra2c) 108240556(adra2db) 108242333 108249957

ALIM:

106513117 106517482 106525354(adra2c) 106535232

NWH:	119408787(adra2db) 119409248 119422669(adra2c) 119430279

AOCE:

111569522 111570710 111576733 111577212

CSEM:

103384182 103387343 103390990 103398493

POV:	109627750 109632596 109641432 109646613

SSEN:

122766216 122770576(adra2c) 122772642 122778146(adra2db)

HHIP:

117752021 117759154 117767767(adra2c) 117769582(adra2db)

LCF:	108875561 108879967 108894164 108899273

SDU:	111217968 111223071 111226458 111233056

SLAL:

111646554 111656645 111664609 111673473(adra2c)

XGL:	120785050(adra2db) 120788280 120797621 120800525(adra2c)

HCQ:	109514276 109518671 109520324 109527378

BPEC:

110157662 110159476 110175748

MALB:

109957837 109971556 109973165 109974257

SASA:

106563753 106577568 106603007 106604836 106608696 106610412 106611869

OTW:	112214969 112220759 112228191 112230624 112256085 112261049 121844636 121845046

OMY:	110488611 110500663 110504821 110510201 110514534 110531806 110534927 118936798

OGO:	123993255 123993434 124007501 124008766 124011426 124014535 124020534

ONE:	115115775 115130525 115133780 115136395 115138904 115147079

SALP:

111951050 111960211 111963685 111965391 111967376 111981428

SNH:	120020915 120030217 120039905 120040006 120048198 120049228(adra2c) 120056659 120062396

ELS:	105020660 105020820 105020821 105024904 105025824

SFM:	108925693 108931116 108936784

PKI:	111842631 111853067 111855457

AANG:

118224324 118227125(adra2c) 118231465 118236285

LOC:	102694090 102695778(adra2c)

PSPA:

121296895 121301912 121323853 121327661

ARUT:

117409626 117413076 117420996

LCM:	102353707 102355811(ADRA2C)

CMK:	103177286 103186334(adra2c)

RTP:	109920122(adra2c)

BBEL:

PPYR:

PCHN:

PCLA:

BGT:

CRG:

MMER:

Reference

PMID:2842764

Authors

Regan JW, Kobilka TS, Yang-Feng TL, Caron MG, Lefkowitz RJ, Kobilka BK

Title

Cloning and expression of a human kidney cDNA for an alpha 2-adrenergic receptor subtype.

Journal

Proc Natl Acad Sci U S A 85:6301-5 (1988)
DOI:10.1073/pnas.85.17.6301

Sequence

[hsa:152]

LinkDB

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