KEGG ORTHOLOGY: K04202

ORTHOLOGY: K04202

Entry

K04202                      KO

Symbol

MC4R

Name

melanocortin 4 receptor

Pathway

map04080

Neuroactive ligand-receptor interaction

map04081

Hormone signaling

map04082

Neuroactive ligand signaling

Disease

H02106

Genetic obesity

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    K04202  MC4R; melanocortin 4 receptor
   04082 Neuroactive ligand signaling
    K04202  MC4R; melanocortin 4 receptor
   04081 Hormone signaling
    K04202  MC4R; melanocortin 4 receptor
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors
    K04202  MC4R; melanocortin 4 receptor
G protein-coupled receptors [BR:ko04030]
Rhodopsin family
  Peptide
   Melanocortin
    K04202  MC4R; melanocortin 4 receptor

Other DBs

GO:

0004977

TC:	9.A.14.2.3

Genes

HSA:	4160(MC4R)

PTR:	468556(MC4R)

PPS:	100980364(MC4R)

GGO:	101153120(MC4R)

PON:	100459483(MC4R)

PPYG:

129018967(MC4R)

NLE:	100594461(MC4R)

HMH:	116468064(MC4R)

SSYN:

129489500(MC4R)

MCC:	698596(MC4R)

MCF:	102119180(MC4R)

MTHB:

126941399

MNI:	105477032(MC4R)

CSAB:

103244186(MC4R)

CATY:

105589987(MC4R)

PANU:

101016173(MC4R)

TGE:	112611574(MC4R)

MLEU:

105553921(MC4R)

RRO:	104662856(MC4R)

RBB:	108526391(MC4R)

TFN:	117098841(MC4R)

PTEH:

111546873(MC4R)

CANG:

105517078(MC4R)

CJC:	100405042(MC4R)

SBQ:	101044042(MC4R)

CIMI:

108304540(MC4R)

ANAN:

105712953(MC4R)

CSYR:

103262067(MC4R)

MMUR:

105881692(MC4R)

LCAT:

123621607(MC4R)

ERUF:

138383253(MC4R)

PCOQ:

105816362(MC4R)

OGA:	100957011(MC4R)

MMU:	17202(Mc4r)

MCAL:

110284992(Mc4r)

MPAH:

110333345(Mc4r)

RNO:	25635(Mc4r)

MCOC:

116087284(Mc4r)

ANU:	117719956(Mc4r)

ASYL:

127663812(Mc4r)

MUN:	110540004(Mc4r)

CGE:	100759720(Mc4r)

MAUA:

101830440(Mc4r)

PROB:

127234084(Mc4r)

PLEU:

114682350(Mc4r)

PMAV:

102905826(Mc4r)

MORG:

121438764(Mc4r)

MFOT:

126511113

AAMP:

119814810(Mc4r)

CNL:	130886845(Mc4r)

NGI:	103739614(Mc4r)

HGL:	101725964(Mc4r)

CPOC:

100379598(Mc4r)

CCAN:

109677508(Mc4r)

DORD:

105987622(Mc4r)

DSP:	122098057(Mc4r)

DMER:

138831557(Mc4r)

PLOP:

125364033(Mc4r)

NCAR:

124965585

MMMA:

107139376(Mc4r)

ITI:	101976531(Mc4r)

OCU:	100355375 127492371

OPI:	101518525(MC4R)

OCZ:	121159572(MC4R)

TUP:	102502724(MC4R)

GVR:	103606721(MC4R)

CFA:	483961(MC4R)

CLUD:

112644048(MC4R)

VVP:	112919220(MC4R)

VLG:	121482150(MC4R)

NPO:	129495612 129514654

AML:	100474731(MC4R)

UMR:	103675996(MC4R)

UAH:	113253469(MC4R)

UAR:	123787433(MC4R)

ELK:

111154261

LLV:

125082279

MPUF:

101670085(MC4R)

MNP:	132023967(MC4R)

MLK:	131811265(MC4R)

NVS:	122901906(MC4R)

ORO:	101370198(MC4R)

EJU:	114208876(MC4R)

ZCA:	113912815(MC4R)

MLX:	118004422(MC4R)

NSU:	110577140(MC4R)

LWW:	102730220(MC4R)

FCA:	101081334(MC4R)

PYU:	121032860(MC4R)

PCOO:

112868253(MC4R)

PBG:	122470817(MC4R)

PVIV:

125149332(MC4R)

LRUF:

124517132

LGF:	123588069(MC4R)

AJU:

106986994

PTG:	102972736(MC4R)

PPAD:

109275650(MC4R)

PUC:

125914728

PLEZ:

122203742(MC4R)

HHV:	120230797(MC4R)

BTA:	281300(MC4R)

BOM:	102286686(MC4R)

BIU:	109577718(MC4R)

BBUB:

102415955(MC4R)

BKE:	129635740(MC4R)

BBIS:

104999239(MC4R)

CHX:	100861239(MC4R)

OAS:	100147707(MC4R)

BTAX:

128067528(MC4R)

CSUM:

138097674(MC4R)

ODA:	120880878(MC4R)

CCAD:

122425604(MC4R)

MREE:

136167685(MC4R)

OVR:	110142105(MC4R)

MBEZ:

129549890(MC4R)

SSC:	397359(MC4R)

CFR:	102515844(MC4R)

CBAI:

105073909(MC4R)

CDK:	105088991(MC4R)

VPC:	102544948(MC4R)

BACU:

103012177(MC4R)

BMUS:

118879954(MC4R)

LVE:	103084384(MC4R)

OOR:	101274578(MC4R)

LALB:

132503974(MC4R)

GMF:	115859380(MC4R)

DDP:	132436650(MC4R)

DLE:	111180149(MC4R)

PCAD:

102981580(MC4R)

PSIU:

116738925(MC4R)

PPHC:

136132700(MC4R)

NASI:

112406169(MC4R)

ECB:	100050469(MC4R)

EPZ:	103565805(MC4R)

EAI:	106842731(MC4R)

MYB:	102246399(MC4R)

MYD:	102758991(MC4R)

MMYO:

118663448(MC4R)

MLF:	102427511(MC4R)

MDT:	132239644(MC4R)

MYUM:

139014573(MC4R)

PKL:	118708243(MC4R)

EFUS:

103293275(MC4R)

MNA:	107545417(MC4R)

DRO:	112322828(MC4R)

SHON:

118980447(MC4R)

AJM:	119054127(MC4R)

PDIC:

114506828(MC4R)

PHAS:

123826191(MC4R)

MMF:	118618795(MC4R)

PPAM:

129078903(MC4R)

HAI:	109381727(MC4R)

RFQ:	117011811(MC4R)

PALE:

102895001(MC4R)

PGIG:

120583144(MC4R)

PVP:	105292723(MC4R)

RAY:	107516200(MC4R)

MJV:	108399599(MC4R)

TOD:	119243766(MC4R)

SARA:

101550038(MC4R)

SFUM:

130016292(MC4R)

SETR:

126020599(MC4R)

LAV:	100677251(MC4R)

TMU:

101345462

ETF:	101658138(MC4R)

DNM:	101424077(MC4R)

MDO:	100016168(MC4R)

GAS:	123231625(MC4R)

SHR:	100921147(MC4R)

AFZ:

127543668

PCW:	110214735(MC4R)

TVP:	118856241(MC4R)

PBRV:

138171289(MC4R)

MLAO:

141500037(MC4R)

OAA:	100073912(MC4R)

TACU:

119948893(MC4R)

GGA:	428485(MC4R)

PCOC:

116226558(MC4R)

MGP:	100547162(MC4R)

CJO:	107309553(MC4R)

TPAI:

128087701(MC4R)

LMUT:

125691062(MC4R)

NMEL:

110394189(MC4R)

APLA:

101793277(MC4R)

AACU:

137851754(MC4R)

ACYG:

106039909(MC4R)

CATA:

118258437(MC4R)

AFUL:

116486296(MC4R)

TGU:	100218148(MC4R)

LSR:	110482814(MC4R)

SCAN:

103819923(MC4R)

PMOA:

120508359(MC4R)

OTC:	121348364(MC4R)

PRUF:

121358064(MC4R)

ATRC:

139603111(MC4R)

GFR:	102045519(MC4R)

FAB:	101809388 101816499

OMA:	130249542(MC4R)

PHI:	102114186(MC4R)

PMAJ:

107200903(MC4R)

CCAE:

111923872(MC4R)

CCW:	104689833(MC4R)

CBRC:

103618741(MC4R)

ACOE:

138105797(MC4R)

ETL:	114062297(MC4R)

ZAB:	102060789(MC4R)

ZLE:	135443210(MC4R)

ACHL:

103799350(MC4R)

SVG:	106850808(MC4R)

MMEA:

130577647(MC4R)

HRT:	120754432(MC4R)

SATI:

136368091(MC4R)

CFAI:

136302727(MC4R)

CCIC:

134047978(MC4R)

FPG:	101914418(MC4R)

FCH:	102055472(MC4R)

CCRI:

104156719(MC4R)

NNT:	104399008(MC4R)

SHAB:

115608233(MC4R)

ACUN:

113477356(MC4R)

SURA:

141953975(MC4R)

TALA:

104368924(MC4R)

ACHC:

115352970(MC4R)

HALD:

104312234(MC4R)

HLE:	104843191(MC4R)

AGEN:

126048618

HHAR:

128140108(MC4R)

BBUT:

142042333(MC4R)

GCL:

127013330

CSTI:

104562641(MC4R)

LDI:	104341588(MC4R)

MNB:	103768875(MC4R)

DPUB:

104300526(MC4R)

PPUS:

135184698(MC4R)

AVIT:

104277871(MC4R)

BRHI:

104492697(MC4R)

EGZ:	104123467(MC4R)

NNI:	104021862(MC4R)

PCRI:

104030602(MC4R)

PCAO:

104041189(MC4R)

PADL:

103919218(MC4R)

AFOR:

103898846(MC4R)

FGA:	104075882(MC4R)

CBOR:

142078240(MC4R)

GSTE:

104252714(MC4R)

CBOY:

140647001(MC4R)

MAME:

142406697(MC4R)

CLV:	102092308(MC4R)

CNIC:

135985481(MC4R)

MUI:	104535442(MC4R)

PGUU:

104468106(MC4R)

PLET:

104620634(MC4R)

EHS:	104505081(MC4R)

CMAC:

104485116(MC4R)

CUCA:

104066785(MC4R)

TEO:	104381840(MC4R)

BREG:

104639190(MC4R)

GAME:

129202927(MC4R)

OHA:	104331196(MC4R)

ACAR:

104532574(MC4R)

CPEA:

104391572(MC4R)

CVF:	104285482(MC4R)

RTD:	128905578(MC4R)

CRID:

134510716(MC4R)

LMIC:

141738315(MC4R)

AAM:	106482335 106482344

AROW:

112977027(MC4R)

NPD:	112951329(MC4R)

TGT:	104579945(MC4R)

DNE:	112992527(MC4R)

SCAM:

104140625(MC4R)

ASN:	102368203(MC4R)

AMJ:	102565056(MC4R)

PSS:	102464037(MC4R)

CIZ:	142008685(MC4R)

CMY:	102933129(MC4R)

CCAY:

125632050(MC4R)

LKP:	140905965(MC4R)

NDS:	141981536(MC4R)

DCC:	119851371(MC4R)

CPIC:

101940602(MC4R)

TST:	117873064(MC4R)

CABI:

116820038(MC4R)

MRV:	120398295(MC4R)

ACS:	100557051(mc4r)

ASAO:

132774518(MC4R)

PVT:	110075427(MC4R)

SUND:

121928738(MC4R)

PBI:	103064645(MC4R)

PMUR:

107283587(MC4R)

CTIG:

120313865(MC4R)

TSR:	106543389(MC4R)

PGUT:

117662492(MC4R)

PCAE:

139316025(MC4R)

APRI:

131195177(MC4R)

PTEX:

113436451(MC4R)

NSS:	113417160(MC4R)

VKO:	123021594(MC4R)

PMUA:

114600989(MC4R)

PRAF:

128417872(MC4R)

ZVI:	118090057(MC4R)

HCG:	128321941(MC4R)

GJA:	107123526(MC4R)

STOW:

125439119(MC4R)

EMC:	129333637(MC4R)

XLA:	108695258(mc4r.S) 108719094(mc4r.L)

XTR:	100486677(mc4r)

NPR:

108802086

RTEM:

120940621(MC4R)

ACAT:

141145894(MC4R)

PADS:

140332024(MC4R)

BBUF:

121002510

BGAR:

122938891(MC4R)

DTC:	141052882(MC4R)

PWL:	138259189(MC4R)

MUO:	115460148(MC4R) 115460254

GSH:	117354853(MC4R)

DRE:	286833(mc4r)

SRX:	107714827 107729066

SANH:

107667291 107678942

SGH:	107567405 107586449

CCAR:

109066501 109094979

CAUA:

113046400 113070184 113078171 113110815

CGIB:

127951337 128023444

PTET:

122357487(mc4r)

LROH:

127174524(mc4r)

GRF:	141344027(mc4r)

OMC:	131526202(mc4r)

PPRM:

120482041(mc4r)

RKG:	130089166(mc4r)

MAMB:

125251564(mc4r)

CIDE:

127505716

CERY:

137002778(mc4r)

MASI:

127440476 127442374

TROS:

130554498(mc4r)

TDW:	130418397(mc4r)

MANU:

129442177(mc4r)

PDAB:

135766902(mc4r)

IPU:	108280642(mc4r)

IFU:	128623917(mc4r)

PHYP:

113543125

SMEO:

124403366(mc4r)

TFD:	113640278(mc4r)

TVC:	132848056(mc4r)

CGAR:

128512925(mc4r)

NGRA:

132871447(mc4r)

TRN:	134302336(mc4r)

AMEX:

103023838(mc4r) 103042955

CMAO:

118797051(mc4r) 118808817

EEE:

113590181

CHAR:

105897233 105900484(mc4r)

SPIL:

134065917 134098194(mc4r)

ASAD:

121687870

TRU:	445900(mc4r)

TFS:	130514056(mc4r)

TNG:	GSTEN00016531G001

LCO:

104930272

NCC:

104961440

TBEN:

117496910(mc4r)

CGOB:

115025688

PGEO:

117465854(mc4r)

GACU:

117537817(mc4r)

EMAC:

134883797(mc4r)

ELY:	117264484(mc4r)

EFO:	125881507(mc4r)

PLEP:

121960681(mc4r)

SLUC:

116040068(mc4r)

ECRA:

117938155(mc4r)

ESP:

116672434

PFLV:

114549272

GAT:	120812049(mc4r)

PPUG:

119199026(mc4r)

AFB:	129110712(mc4r)

CLUM:

117749562(mc4r)

PSWI:

130205963(mc4r)

CANA:

137801900(mc4r)

CVE:

137872022

MSAM:

119912798

SCHU:

122867020(mc4r)

EARM:

139303984(mc4r)

CUD:	121527354(mc4r)

SPUL:

138595766(mc4r)

LMIX:

132994444(mc4r)

HTC:	141807792(mc4r)

ALAT:

119008255(mc4r)

ASTR:

137614164

PKLU:

139220883(mc4r)

MZE:

101476237

ONL:

100695984

OAU:	116311428(mc4r)

OLA:

101174304

OML:	112150984(mc4r)

CSAI:

133423043(mc4r)

XMA:	102234594 102235203 111605751 111605772 111606145 111606152 111606216 111607818 111607827 111607889 111607900 111608026

XCO:

114136639

XHE:	116711464 116711465 116711466

PRET:

PFOR:

PLAI:

PMEI:

GAF:	122824500(mc4r)

PPRL:

129378866(mc4r)

CVG:

107089424

CTUL:

119776940(mc4r)

GMU:	124857705(mc4r)

NFU:

107383086

KMR:	108234679(mc4r)

ALIM:

106522285

NWH:	119426594(mc4r)

EJA:	138204231(mc4r)

BFRE:

138625698(mc4r)

MCEP:

125024417(mc4r)

CSEM:

103377490

POV:

109641149

SSEN:

122769461(mc4r)

SSOE:

131441742(mc4r)

HHIP:

117754124(mc4r)

HSP:	118098583(mc4r)

PPLT:

128425804(mc4r)

SMAU:

118290902(mc4r)

LCF:

108885079

SDU:

111237874

SLAL:

111645796

XGL:	120789933(mc4r)

HCQ:

109518715

SSCV:

125986125(mc4r)

SBIA:

133492582(mc4r)

PEE:	133396343(mc4r)

PTAO:

133470473(mc4r)

BPEC:

110164121

ENY:

140364924

MALB:

109960441

BSPL:

114853319(mc4r)

SJO:	128382245(mc4r)

SSCO:

134002113(mc4r)

TTY:	137173589(mc4r)

GMH:

115537588

SASA:

106569291 106578596 106590056 106599238

STRU:

115154042 115157781 115169741 115195865

OTW:	112215613 112226470(mc4r) 112227564 112261112

OMY:	110490013 110508705 110530343 110535569

OGO:	123990190 124009109 124039201 124040666(mc4r)

ONE:	115101575 115105120 115113950 115131120

OKI:	109871547 109874696 109899054 109909720

OKE:	118360487 118374511 118395107 118402532

OMM:	135507023 135518573 135523158 135558238

OCLA:

139366788 139377333 139386910 139420698

SALP:

111957000 111972617 111979625 112068248

SNH:	120020071(mc4r) 120028003 120051189 120055259

SFON:

129814079 129822817 129824053 129859455

CCLU:

121534829 121549536 121581305

ELS:	105022720 105031182

OEP:	134035231 134036244(mc4r)

SFM:

108927548

PKI:	111846195 111850886

AANG:

118224961 118234343(mc4r)

AROT:

135253913 135260867

CCOG:

133127587 133137650

LOC:

102686557

PSPA:

121308181 121313798(mc4r)

ARUT:

117399736 117435765

PSEX:

120529394(mc4r)

LCM:

102355468

CMK:	103179956(mc4r)

RTP:	109923935(mc4r)

CPLA:

122558724(mc1r) 122564306(mc4r)

CPUN:

140453236(mc1r) 140465110(mc4r)

HOC:

132832335

SCAU:

119965595(mc4r) 119971223(mc1r)

LERI:

129705448 129705489 129711028(mc4r)

HAKA:

140713980(mc4r) 140740993(mc1r)

LRJ:

133340336

BBEL:

109467546 109467548 109478566 109483529

CIN:

100183486

SCLV:

120336205

LPIC:

129271469 129275714 129275715 129275722 129275727

LSAX:

138961454

CANU:

128161068

CVN:	111113423 111136228

OED:

125683031

RPHI:

132720574 132742859

MAEA:

128204894

LAK:	106161515 106177304

NVE:	116610910 5520171

EPA:	110231443 110235480 110236879 110240932 110243031 110248253 110249924 110254526

ATEN:

116286239 116308744

ADF:	107329939 107338828 107339148 107349324

AMIL:

114951101 114951106 114951732 114952782 114965170 114969334 114970410 122953846 122957614 122957617 122957621 122957624 122961441 122961446

MCAZ:

138014304 138019280 138025332 138036164 138037912 138038130 138038133 138046403 138048806 138048809 138049423 138052078 138054666 138054667 138055908 138057409 138057695 138057926 138057928

MFOO:

137974923 137979137 137980957 137989324 137990689 137990998 137990999 137991000 137992838 137995032 137996311 138002530 138003153 138010090 138010091 138010097 138010098

PDAM:

113664897 113666040 113666561 113668521 113670119 113670937 113672701 113678499 113683448 113683541 113684404 113685318 113685490 113685598

SPIS:

111321221 111331766 111333403 111335970 111336278 111346611

DGT:

114529277

XEN:

124446137

HSY:

130621231

RES:	135683429 135687702

» show all

Reference

PMID:8392067

Authors

Gantz I, Miwa H, Konda Y, Shimoto Y, Tashiro T, Watson SJ, DelValle J, Yamada T

Title

Molecular cloning, expression, and gene localization of a fourth melanocortin receptor.

Journal

J Biol Chem 268:15174-9 (1993)

Sequence

[hsa:4160]

LinkDB

DBGET integrated database retrieval system