KEGG   ORTHOLOGY: K04246
Entry
K04246                      KO                                     
Symbol
GPER1, GPR30
Name
G-protein coupled estrogen receptor 1
Pathway
map01522  Endocrine resistance
map04915  Estrogen signaling pathway
map04929  GnRH secretion
Brite
KEGG Orthology (KO) [BR:ko00001]
 09150 Organismal Systems
  09152 Endocrine system
   04929 GnRH secretion
    K04246  GPER1, GPR30; G-protein coupled estrogen receptor 1
   04915 Estrogen signaling pathway
    K04246  GPER1, GPR30; G-protein coupled estrogen receptor 1
 09160 Human Diseases
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    K04246  GPER1, GPR30; G-protein coupled estrogen receptor 1
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors
    K04246  GPER1, GPR30; G-protein coupled estrogen receptor 1
G protein-coupled receptors [BR:ko04030]
 Rhodopsin family
  Others
   Estrogen
    K04246  GPER1, GPR30; G-protein coupled estrogen receptor 1
Other DBs
GO: 0030284 0017082
TC: 9.A.14.13.19
Genes
HSA: 2852(GPER1)
PTR: 107971974(GPER1)
PPS: 100967334 117974319
GGO: 101134828(GPER1)
PON: 112131300(GPER1)
NLE: 105738901(GPER1)
MCC: 696625(GPER1)
MCF: 102135906(GPER1)
MTHB: 126950568
CSAB: 103246891(GPER1)
CATY: 105571771(GPER1)
PANU: 101001376(GPER1)
TGE: 112620592(GPER1)
RRO: 104664942(GPER1)
RBB: 108543623(GPER1)
TFN: 117073483(GPER1)
PTEH: 111523694(GPER1)
CJC: 100407266(GPER1)
SBQ: 101031462(GPER1)
CSYR: 103255740(GPER1)
MMUR: 105868377(GPER1)
LCAT: 123632546(GPER1)
OGA: 100960801(GPER1)
MMU: 76854(Gper1)
MCAL: 110293944(Gper1)
MPAH: 110312834(Gper1)
RNO: 171104(Gper1)
MCOC: 116068650(Gper1)
MUN: 110550693(Gper1)
CGE: 100767871(Gper1)
MAUA: 106021931(Gper1)
PLEU: 114682203(Gper1)
MORG: 121446019(Gper1)
MFOT: 126514338
AAMP: 119824463(Gper1)
NGI: 103748691(Gper1)
HGL: 101702826(Gper1)
CPOC: 100712743(Gper1)
CCAN: 109690358(Gper1)
DORD: 105990953(Gper1)
DSP: 122113564(Gper1)
NCAR: 124969818
OCU: 100347718
OPI: 101527429(GPER1)
TUP: 102483513(GPER1)
GVR: 103582682(GPER1)
CFA: 480808(GPER1)
CLUD: 112640171(GPER1)
VVP: 112929289(GPER1)
VLG: 121487704(GPER1)
AML: 100473291(GPER1)
UMR: 103669929(GPER1)
UAH: 113247719(GPER1)
UAR: 123802530(GPER1)
ELK: 111145647
LLV: 125090159
MPUF: 101688939(GPER1)
ORO: 101365153(GPER1)
EJU: 114199930(GPER1)
ZCA: 113931926(GPER1)
MLX: 117999272(GPER1)
NSU: 110572007(GPER1)
LWW: 102737250(GPER1)
FCA: 101085767(GPER1)
PYU: 121017477(GPER1)
PBG: 122471201(GPER1)
LRUF: 124519124
PTG: 102968991(GPER1)
PPAD: 109251106(GPER1)
AJU: 106966520(GPER1)
HHV: 120227919(GPER1)
BTA: 527831(GPER1)
BOM: 106701585(GPER1)
BIU: 109578308(GPER1)
BBIS: 104998621(GPER1)
CHX: 106503626(GPER1)
OAS: 114110561(GPER1)
ODA: 120856362(GPER1)
CCAD: 122432746(GPER1)
SSC: 100521003(GPER1)
CFR: 102519542(GPER1)
CBAI: 105077878(GPER1)
CDK: 105105866(GPER1)
VPC: 102529683(GPER1)
LVE: 103071067(GPER1)
OOR: 101285933(GPER1)
DLE: 111169364(GPER1)
PCAD: 102988721(GPER1)
PSIU: 116740578(GPER1)
ECB: 102148430(GPER1)
EPZ: 103560283(GPER1)
EAI: 106834760(GPER1)
MYB: 102251080(GPER1)
MYD: 102764548(GPER1)
MMYO: 118659230(GPER1)
MLF: 102437067(GPER1)
MNA: 107537049(GPER1)
PKL: 118715957(GPER1)
HAI: 109380192(GPER1)
DRO: 112319452(GPER1)
SHON: 118995052(GPER1)
AJM: 119043771(GPER1)
PDIC: 114510262(GPER1)
PHAS: 123809637(GPER1)
MMF: 118616381(GPER1)
RFQ: 117016417(GPER1)
PALE: 102895417(GPER1)
PGIG: 120616027(GPER1)
PVP: 105304462(GPER1)
RAY: 107497376(GPER1)
MJV: 108394663(GPER1)
TOD: 119241436(GPER1)
SARA: 105943311(GPER1)
LAV: 100677095(GPER1)
TMU: 101355130
ETF: 101659430(GPER1)
MDO: 100028426(GPER1)
GAS: 123234070(GPER1)
SHR: 100926545(GPER1)
PCW: 110202499(GPER1)
OAA: 100085788(GPER1)
GGA: 416457(GPER1)
PCOC: 116237522(GPER1)
MGP: 116216164(GPER1)
CJO: 107320567(GPER1)
NMEL: 110406126(GPER1)
APLA: 101792901(GPER1)
ACYG: 106033534(GPER1)
AFUL: 116495466(GPER1)
TGU: 101233082(GPER1)
LSR: 110475498(GPER1)
SCAN: 103817645(GPER1)
PMOA: 120513270(GPER1)
OTC: 121334574(GPER1)
PRUF: 121350933(GPER1)
GFR: 102044731(GPER1)
FAB: 101806702(GPER1)
PHI: 102101274(GPER1)
PMAJ: 107211086(GPER1)
CCAE: 111936072(GPER1)
CCW: 104684828(GPER1)
CBRC: 103615434(GPER1)
ETL: 114054763(GPER1)
ZAB: 102061655(GPER1)
ACHL: 103802767(GPER1)
FPG: 101923670(GPER1)
FCH: 102056951(GPER1)
CLV: 102091130(GPER1)
EGZ: 104128959(GPER1)
NNI: 104015076(GPER1)
PLET: 104626846(GPER1)
PCRI: 104034448(GPER1)
PCAO: 104052921(GPER1)
ACUN: 113485506(GPER1)
TALA: 104369360(GPER1)
PADL: 103913519(GPER1)
AFOR: 103904857(GPER1)
ACHC: 115335659(GPER1)
HALD: 104312910(GPER1)
HLE: 104833546(GPER1)
AGEN: 126034183
GCL: 127022263
CCRI: 104157187(GPER1)
CSTI: 104554052(GPER1)
EHS: 104505600(GPER1)
CMAC: 104485776(GPER1)
MUI: 104544462(GPER1)
FGA: 104081742(GPER1)
GSTE: 104253292(GPER1)
LDI: 104345895(GPER1)
MNB: 103775941(GPER1)
OHA: 104337918(GPER1)
NNT: 104400503(GPER1)
DPUB: 104307635(GPER1)
PGUU: 104469634(GPER1)
ACAR: 104531333(GPER1)
CPEA: 104393750(GPER1)
AVIT: 104270467(GPER1)
CVF: 104287096(GPER1)
CUCA: 104065988(GPER1)
TEO: 104374921(GPER1)
BRHI: 104497585(GPER1)
AAM: 106491317(GPER1)
AROW: 112974326(GPER1)
NPD: 112959999(GPER1)
TGT: 104570205(GPER1)
DNE: 112992831(GPER1)
SCAM: 104153944(GPER1)
ASN: 102378723(GPER1)
AMJ: 102568205(GPER1)
CPOO: 109314739(GPER1)
GGN: 109294515(GPER1)
PSS: 102456168(GPER1)
CMY: 122461325(GPER1)
CPIC: 101936243(GPER1)
TST: 117884019(GPER1)
CABI: 116832918(GPER1) 116834751
MRV: 120372780(GPER1)
ACS: 100554247(gper1)
PVT: 110084713(GPER1)
SUND: 121937447(GPER1)
PBI: 103057711(GPER1)
PMUR: 107289116(GPER1)
CTIG: 120319273(GPER1)
TSR: 106544174(GPER1)
PGUT: 117679539(GPER1)
VKO: 123024939(GPER1)
PMUA: 114584941(GPER1)
ZVI: 118092788(GPER1)
GJA: 107124243(GPER1)
STOW: 125431991(GPER1)
XLA: 108701565(gper1.L) 108703136(gper1.S)
XTR: 100135723(gper1)
NPR: 108798389(GPER1)
RTEM: 120943440(GPER1)
BBUF: 121008648(GPER1)
BGAR: 122945085(GPER1)
DRE: 565271(gper1)
PPRM: 120479777 120489302(gper1)
MAMB: 125258053 125270260(gper1)
IPU: 108256794(gper1)
PHYP: 113536137(gper1)
SMEO: 124376136(gper1)
TFD: 113634869(gper1)
AMEX: 103023668(gper1) 103030072
ELY: 117268988(gper1)
EFO: 125878997(gper1) 125880527
PLEP: 121956121(gper1)
SLUC: 116044348 116059411(gper1)
ECRA: 117937190 117958660(gper1)
GAT: 120818983 120827971(gper1)
PPUG: 119213166 119221145(gper1)
MSAM: 119891751(gper1) 119915540
CUD: 121503844(gper1)
ALAT: 119009776 119014202(gper1)
ONL: 100699814(gper1) 102081621
OAU: 116318376(gper1) 116319901
OLA: 101172413(gper1) 105356557
OML: 112146546(gper1) 118600179
XCO: 114158718 114159403(gper1)
XHE: 116726749 116734874(gper1)
PRET: 103468695 103481069(gper1)
PLAI: 106936088(gper1) 106964067
PMEI: 106903578(gper1) 106934028
GAF: 122821507(gper1) 122822770
CVG: 107083076(gper1) 107085030
CTUL: 119785280(gper1) 119793732
NFU: 107378397 107388040(gper1)
KMR: 108237198 108243707(gper1)
ALIM: 106528673(gper1)
NWH: 119421782(gper1) 119423424
MCEP: 124997776(gper1) 125022246
POV: 109634211(gper1)
SSEN: 122759143 122763919(gper1)
HHIP: 117753369 117766091(gper1)
HSP: 118100246 118123611(gper1)
LCF: 108886760 108902953(gper1)
SDU: 111217714(gper1) 111220411
SLAL: 111658646 111660453(gper1)
XGL: 120788154(gper1) 120794188
HCQ: 109519352(gper1)
BPEC: 110169641(gper1)
MALB: 109965998(gper1)
BSPL: 114845724 114859864(gper1)
OGO: 124000608 124016151(gper1)
SFM: 108923915(gper1)
LOC: 102683951(gper1)
PSEX: 120542757(gper1)
LCM: 102356169(GPER1)
CMK: 103185137
GAE: 121379102
 » show all
Reference
PMID:9070864
  Authors
Feng Y, Gregor P
  Title
Cloning of a novel member of the G protein-coupled receptor family related to peptide receptors.
  Journal
Biochem Biophys Res Commun 231:651-4 (1997)
DOI:10.1006/bbrc.1997.6161
  Sequence
[hsa:2852]
Reference
  Authors
Prossnitz ER, Barton M
  Title
The G-protein-coupled estrogen receptor GPER in health and disease.
  Journal
Nat Rev Endocrinol 7:715-26 (2011)
DOI:10.1038/nrendo.2011.122
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