KEGG ORTHOLOGY: K04267

ORTHOLOGY: K04267

Entry

K04267                      KO

Symbol

ADORA2B

Name

adenosine receptor A2b

Pathway

map04015

Rap1 signaling pathway

map04020

Calcium signaling pathway

map04080

Neuroactive ligand-receptor interaction

map04082

Neuroactive ligand signaling

map04270

Vascular smooth muscle contraction

map05034

Alcoholism

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    K04267  ADORA2B; adenosine receptor A2b
   04020 Calcium signaling pathway
    K04267  ADORA2B; adenosine receptor A2b
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    K04267  ADORA2B; adenosine receptor A2b
   04082 Neuroactive ligand signaling
    K04267  ADORA2B; adenosine receptor A2b
09150 Organismal Systems
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    K04267  ADORA2B; adenosine receptor A2b
09160 Human Diseases
  09165 Substance dependence
   05034 Alcoholism
    K04267  ADORA2B; adenosine receptor A2b
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors
    K04267  ADORA2B; adenosine receptor A2b
G protein-coupled receptors [BR:ko04030]
Rhodopsin family
  Base and nucleoside
   Adenosine
    K04267  ADORA2B; adenosine receptor A2b

Other DBs

GO:

0001609

Genes

HSA:	136(ADORA2B)

PTR:	455009(ADORA2B)

PPS:	100994290(ADORA2B)

GGO:	101148779(ADORA2B)

PON:	100448500(ADORA2B)

PPYG:

129016874(ADORA2B)

NLE:	100600364(ADORA2B)

HMH:	116463821 116463827

SSYN:

129470741(ADORA2B)

MCC:	696848(ADORA2B)

MCF:	102123462(ADORA2B)

MTHB:

126938806

MNI:	105491088(ADORA2B)

CSAB:

103242456(ADORA2B)

CATY:

105571937(ADORA2B)

PANU:

101001972(ADORA2B)

TGE:	112609528(ADORA2B)

MLEU:

105535993(ADORA2B)

RRO:	104681441(ADORA2B)

RBB:	108522165(ADORA2B)

TFN:	117066424(ADORA2B)

PTEH:

111526446 113225159(ADORA2B)

CANG:

105523190(ADORA2B)

CJC:	100388327(ADORA2B)

SBQ:	101044944(ADORA2B)

CIMI:

108281295(ADORA2B)

ANAN:

110569112(ADORA2B)

CSYR:

103264902(ADORA2B)

LCAT:

123650568(ADORA2B)

PCOQ:

105816111(ADORA2B)

OGA:	100965513(ADORA2B)

MMU:	11541(Adora2b)

MCAL:

110305306(Adora2b)

MPAH:

110332259(Adora2b)

RNO:	29316(Adora2b)

MCOC:

116076778(Adora2b)

ANU:	117710870(Adora2b)

ASYL:

127694792(Adora2b)

MUN:	110549785(Adora2b)

CGE:	100759954(Adora2b)

MAUA:

101832697(Adora2b)

PROB:

127219155(Adora2b)

PLEU:

114682956(Adora2b)

MORG:

121456885(Adora2b)

MFOT:

126514641

AAMP:

119812821(Adora2b)

NGI:	103727344(Adora2b)

HGL:	106007570(Adora2b)

CPOC:

100727842(Adora2b)

CCAN:

109699496(Adora2b)

DORD:

105985735(Adora2b)

DSP:	122103331(Adora2b)

PLOP:

125366199(Adora2b)

NCAR:

124980873

MMMA:

107160170(Adora2b)

ITI:	101961606(Adora2b)

OCU:	100008951(ADORA2B)

OPI:	101536064(ADORA2B)

TUP:	102488122(ADORA2B)

GVR:	103588970(ADORA2B)

CFA:	403410(ADORA2B)

CLUD:

112647295(ADORA2B)

VVP:	112924933(ADORA2B)

VLG:	121499505(ADORA2B)

NPO:	129496986(ADORA2B)

AML:	100464166(ADORA2B)

UMR:	103658552(ADORA2B)

UAH:	113271262(ADORA2B)

UAR:	123779774(ADORA2B)

ELK:

111139483

LLV:

125088138

MPUF:

101680379(ADORA2B)

MNP:	132003952(ADORA2B)

MLK:	131816857(ADORA2B)

NVS:	122906802(ADORA2B)

ORO:	101362544(ADORA2B)

EJU:	114198224(ADORA2B)

ZCA:	113939424(ADORA2B)

MLX:	118000116(ADORA2B)

NSU:	110584643(ADORA2B)

LWW:	102744451(ADORA2B)

FCA:	109494208(ADORA2B)

PYU:	121015846(ADORA2B)

PCOO:

112857131(ADORA2B)

PBG:	122485007(ADORA2B)

PVIV:

125151673(ADORA2B)

LRUF:

124519629

LGF:	123603070(ADORA2B)

AJU:

106981421

PTG:	102961941(ADORA2B)

PPAD:

109245813(ADORA2B)

PUC:

125927570

PLEZ:

122207354(ADORA2B)

HHV:	120228751(ADORA2B)

BTA:	529760(ADORA2B)

BOM:	102268290(ADORA2B)

BIU:	109573399(ADORA2B)

BBUB:

102406905(ADORA2B)

BBIS:

104990684(ADORA2B)

CHX:	102179134(ADORA2B)

OAS:	101107715(ADORA2B)

BTAX:

128065233(ADORA2B)

CSUM:

138083008(ADORA2B)

ODA:	120867417(ADORA2B)

CCAD:

122444716(ADORA2B)

MREE:

136149135(ADORA2B)

OVR:	110138942(ADORA2B)

MBEZ:

129544185(ADORA2B)

SSC:	606745(ADORA2B)

CFR:	102517454(ADORA2B)

CBAI:

105061675(ADORA2B)

CDK:	105085087(ADORA2B)

VPC:	102543510(ADORA2B)

BACU:

102998682(ADORA2B)

BMUS:

118887508(ADORA2B)

LVE:	103078017(ADORA2B)

OOR:	101286598(ADORA2B)

LALB:

132511771(ADORA2B)

DLE:	111167746(ADORA2B)

PCAD:

102986621(ADORA2B)

PSIU:

116745445(ADORA2B)

PPHC:

136138787(ADORA2B)

NASI:

112405188(ADORA2B)

ECB:	100063319(ADORA2B)

EPZ:	103560476(ADORA2B)

EAI:	106838859(ADORA2B)

MYB:	102260920(ADORA2B)

MYD:	102773620(ADORA2B)

MMYO:

118649374(ADORA2B)

MLF:	102439466(ADORA2B)

MDT:	132217963(ADORA2B)

MYUM:

138994021(ADORA2B)

PKL:	118704690(ADORA2B)

EFUS:

103299369(ADORA2B)

MNA:	107524507(ADORA2B)

DRO:	112308785(ADORA2B)

SHON:

119002796(ADORA2B)

AJM:	119064469(ADORA2B)

PDIC:

114515089(ADORA2B)

PHAS:

123809296(ADORA2B)

MMF:	118641250(ADORA2B)

PPAM:

129068779(ADORA2B)

HAI:	109382179(ADORA2B)

RFQ:	117013484(ADORA2B)

PALE:

102894821(ADORA2B)

PGIG:

120589817(ADORA2B)

PVP:	105291304(ADORA2B)

RAY:	107511058(ADORA2B)

MJV:	108403987(ADORA2B)

TOD:	119231518(ADORA2B)

SARA:

101545171(ADORA2B)

SFUM:

130043441(ADORA2B)

SETR:

126013733(ADORA2B)

LAV:	100675139(ADORA2B)

TMU:

101358749

ETF:	101651597(ADORA2B)

DNM:	101440009(ADORA2B)

MDO:	100617435(ADORA2B)

GAS:	123247463(ADORA2B)

SHR:	100913531(ADORA2B)

AFZ:

127558774

PCW:	110222171(ADORA2B)

TVP:	118856871(ADORA2B)

PBRV:

138162434(ADORA2B)

OAA:	100078270(ADORA2B)

TACU:

119939724(ADORA2B)

GGA:	395971(ADORA2B)

PCOC:

116228020(ADORA2B)

MGP:	100541323(ADORA2B)

CJO:	107322414(ADORA2B)

TPAI:

128083594(ADORA2B)

LMUT:

125703140(ADORA2B)

NMEL:

110407643(ADORA2B)

APLA:

101800579(ADORA2B)

ACYG:

106045790(ADORA2B)

CATA:

118255064(ADORA2B)

AFUL:

116497275(ADORA2B)

TGU:	100220469(ADORA2B)

LSR:	110467693(ADORA2B)

SCAN:

103820144(ADORA2B)

PMOA:

120507748(ADORA2B)

OTC:	121345886(ADORA2B)

PRUF:

121361609(ADORA2B)

ATRC:

139600083(ADORA2B)

GFR:	102041688(ADORA2B)

FAB:	101808372(ADORA2B)

OMA:	130260900(ADORA2B)

PHI:	102107785(ADORA2B)

PMAJ:

107212777(ADORA2B)

CCAE:

111937793(ADORA2B)

CCW:	104691038(ADORA2B)

CBRC:

103613350

ACOE:

138120528(ADORA2B)

ETL:	114061259(ADORA2B)

ZAB:	102070085(ADORA2B)

ZLE:	135455711(ADORA2B)

ACHL:

103800055(ADORA2B)

SVG:	106853307(ADORA2B)

MMEA:

130576951(ADORA2B)

HRT:	120761233(ADORA2B)

SATI:

136370154(ADORA2B)

CCIC:

134052609(ADORA2B)

FPG:	101913216(ADORA2B)

FCH:	102048085(ADORA2B)

CCRI:

104168317(ADORA2B)

NNT:	104410437(ADORA2B)

SHAB:

115601990(ADORA2B)

ACUN:

113487115(ADORA2B)

TALA:

104365588(ADORA2B)

ACHC:

115346874(ADORA2B)

HALD:

104312811

HLE:	104835613(ADORA2B)

AGEN:

126039976

HHAR:

128148824(ADORA2B)

GCL:

127024493

CSTI:

104564206(ADORA2B)

MNB:

103771701

DPUB:

104302740(ADORA2B)

PPUS:

135187716(ADORA2B)

AVIT:

104277439(ADORA2B)

BRHI:

104499062(ADORA2B)

EGZ:	104121911(ADORA2B)

NNI:	104012188(ADORA2B)

PCRI:

104039136(ADORA2B)

PCAO:

104049802

PADL:

103920799(ADORA2B)

AFOR:

103897992(ADORA2B)

FGA:	104076070(ADORA2B)

GSTE:

104262547(ADORA2B)

CBOY:

140660720(ADORA2B)

CLV:	102095318(ADORA2B)

CNIC:

135995614(ADORA2B)

MUI:	104538528(ADORA2B)

PGUU:

104467539

PLET:

104616106

EHS:	104509249(ADORA2B)

CMAC:

104481973

CUCA:

104057145(ADORA2B)

TEO:	104384451(ADORA2B)

BREG:

104640508(ADORA2B)

OHA:	104339607(ADORA2B)

ACAR:

104519646(ADORA2B)

CPEA:

104398930(ADORA2B)

CVF:	104284387(ADORA2B)

RTD:	128912801(ADORA2B)

CRID:

134518524(ADORA2B)

AAM:	106493737(ADORA2B)

AROW:

112960702(ADORA2B)

NPD:	112945379(ADORA2B)

TGT:	104572413(ADORA2B)

DNE:	112983934(ADORA2B)

SCAM:

104142804(ADORA2B)

ASN:	102371776(ADORA2B)

AMJ:	102565084(ADORA2B)

CPOO:

109317221(ADORA2B)

GGN:	109293350(ADORA2B)

PSS:	102460408(ADORA2B)

CMY:	102936804(ADORA2B)

CCAY:

125623770(ADORA2B)

DCC:	119844457(ADORA2B)

CPIC:

101951801(ADORA2B)

TST:	117867365(ADORA2B)

CABI:

116827036(ADORA2B)

MRV:	120387233(ADORA2B)

ASAO:

132763410(ADORA2B)

PVT:	110087390(ADORA2B)

SUND:

121917049(ADORA2B)

PBI:

103050113

PMUR:

107284456

CTIG:

120318840(ADORA2B)

TSR:

106548851

PGUT:

117658681(ADORA2B)

APRI:

131188529(ADORA2B)

PTEX:

113453435 113453454

NSS:

113429384

VKO:	123023579(ADORA2B)

PMUA:

114585197(ADORA2B)

PRAF:

128403044(ADORA2B)

ZVI:	118097118(ADORA2B)

HCG:	128336064 128336260

GJA:	107119561(ADORA2B)

STOW:

125445569(ADORA2B)

EMC:	129344739(ADORA2B)

XLA:	108707937 108709185(adora2b.S)

XTR:	100496230(adora2b)

NPR:	108790722(ADORA2B)

RTEM:

120927732(ADORA2B)

ACAT:

141129092(ADORA2B)

BBUF:

120994650(ADORA2B)

BGAR:

122930398(ADORA2B)

DTC:	141079757(ADORA2B)

PWL:	138285846(ADORA2B) 138304377

MUO:	115476232 115482457(ADORA2B)

GSH:	117349006(ADORA2B)

DRE:	560100(adora2b)

SRX:	107712140 107731023

SANH:

107665025 107688642

SGH:	107587731 107595487

CCAR:

109070668 109073849

CAUA:

113049728 113081331

CGIB:

127957420 127996642

PTET:

122345216(adora2b)

LROH:

127165640(adora2b)

GRF:	141334777(adora2b)

OMC:	131540947(adora2b)

PPRM:

120472139

RKG:	130071385(adora2b)

MAMB:

125267957(adora2b)

CIDE:

127512677

CERY:

137034764(adora2b)

MASI:

127421406 127439062

TDW:	130419406(adora2b)

MANU:

129440954(adora2b)

PDAB:

135774278(adora2b)

IPU:

108259885

IFU:	128603673(adora2b) 128606756

PHYP:

113531619(adora2b)

SMEO:

124379510(adora2b) 124384926

TFD:	113651732 113663379(adora2b)

TVC:	132840793(adora2b)

CGAR:

128512441(adora2b)

NGRA:

132875362(adora2b)

TRN:	134303498(adora2b)

AMEX:

103021368(adora2b)

CMAO:

118814354(adora2b)

EEE:	113573789(adora2b)

CHAR:

105895322(adora2b)

SPIL:

134079994(adora2b)

TRU:	101063228(adora2b)

TFS:	130537126(adora2b)

TNG:	GSTEN00016244G001

LCO:	104923431(adora2b)

NCC:	104942049(adora2b)

TBEN:

117469972(adora2b)

CGOB:

115018736(adora2b)

PGEO:

117458790(adora2b)

GACU:

117557247(adora2b)

EMAC:

134871709(adora2b)

ELY:	117270879(adora2b)

EFO:	125898278(adora2b)

PLEP:

121938480(adora2b)

SLUC:

116058210(adora2b)

ECRA:

117955602(adora2b)

ESP:	116700558(adora2b)

PFLV:

114566832(adora2b)

GAT:	120822464(adora2b)

PPUG:

119214946(adora2b)

AFB:	129113858(adora2b)

CLUM:

117742403(adora2b)

PSWI:

130191739(adora2b)

CANA:

137802502(adora2b)

CVE:	137886821(adora2b)

MSAM:

119895301(adora2b)

SCHU:

122888111(adora2b)

CUD:	121518840(adora2b)

SPUL:

138604485(adora2b)

LMIX:

132988667(adora2b)

ALAT:

119031439(adora2b)

ASTR:

137606582(adora2b)

MZE:	101468592(adora2b)

ONL:	100703029(adora2b)

OAU:	116331909(adora2b)

OLA:	101172755(adora2b)

OML:	112141792(adora2b)

CSAI:

133459798(adora2b)

XMA:	102218185(adora2b)

XCO:	114153283(adora2b)

XHE:	116728534(adora2b)

PRET:

103476035(adora2b)

PFOR:

103133869(adora2b)

PLAI:

106949392(adora2b)

PMEI:

106919388(adora2b)

GAF:	122845200(adora2b)

PPRL:

129368498(adora2b)

CVG:	107091726(adora2b)

CTUL:

119791483(adora2b)

GMU:	124876865(adora2b)

NFU:	107386647(adora2b)

KMR:	108233920(adora2b)

ALIM:

106525392(adora2b)

NWH:	119420622(adora2b)

AOCE:

111575188(adora2b)

EJA:	138196675(adora2b)

BFRE:

138622147(adora2b)

MCEP:

125020931(adora2b)

CSEM:

103394908

POV:	109628454(adora2b)

SSEN:

122774370 122779715(adora2b)

SSOE:

131458446(adora2b)

HHIP:

117774050(adora2b)

HSP:	118121711(adora2b)

PPLT:

128457512(adora2b)

SMAU:

118300781(adora2b)

LCF:

108893222

SDU:	111222270(adora2b)

SLAL:

111663942(adora2b)

XGL:	120802569(adora2b)

HCQ:	109531117(adora2b)

SSCV:

125982702(adora2b)

SBIA:

133491538(adora2b) 133500616

PEE:	133415656(adora2b)

PTAO:

133467567(adora2b)

BPEC:

110165141(adora2b)

ENY:	140361027(adora2b)

MALB:

109960460(adora2b)

BSPL:

114870070(adora2b)

SJO:	128370859(adora2b)

SSCO:

133993822(adora2b)

GMH:	115547167(adora2b)

SASA:

106567979(adora2b) 106603509

STRU:

115148855 115155094

OTW:	112228570 112259357

OMY:	110533633(adora2b) 110537491

OGO:	123994587(adora2b) 124000727

ONE:	115105532(adora2b) 115135921

OKI:	109872643 109892130(adora2b)

OKE:	118390713(adora2b) 118391681

OMM:	135548598 135550703

OCLA:

139418246 139423108

SALP:

111950047 111980343(adora2b)

SNH:	120044325 120057452(adora2b)

CCLU:

121573551 121579444

ELS:	105027548(adora2b)

OEP:	134039459(adora2b)

SFM:	108935999(adora2b)

PKI:	111854790(adora2b)

AANG:

118210237 118229938 118236266(adora2b)

AROT:

135236513 135263848(adora2b)

CCOG:

133107958 133134031(adora2b)

LOC:	102692578(adora2b)

PSPA:

121295990 121305072(adora2b) 121327797

ARUT:

117425239 117430733 117964224

PSEX:

120531548(adora2b)

LCM:	102353646(ADORA2B)

CMK:	103180544(adora2b)

CPLA:

122563847(adora2b)

HOC:	132830308(adora2b)

LERI:

129710501(adora2b)

BFO:

118428575

SPU:

582743

LPIC:

129254460 129260591 129265294 129272705 129273565 129275718 129276041 129276344 129277310

AJJ:	139957000 139958614 139962717 139962843 139968185 139971281 139972156 139981022

ARUN:

117290098 117290678 117291754 117293023 117301111

AAMU:

139938247 139939081 139939353 139950133

AFIL:

140136351 140138481 140149561 140150092 140150093 140158100 140158443 140163253 140163528 140172400

AJC:

117104325

PFLL:

139120593 139120594 139126609 139145073 139150012 139150247

ADR:

AFLR:

APLN:

CSEC:

BROR:

DMK:

AFRA:

MNZ:

TCF:

PPOI:

CSCU:

CVS:	136978635 136979381

LPOL:

106475636

PVUL:

126812559 130010910

PCAN:

112555159

LSAX:

138949685 138973135 138975652 138976667

GAE:	121366284 121370096 121371244 121389049

HRF:	124115860 124116071 124125969 124134131 124145816

HRJ:	124255682 124268830 124279474 124282325

HASI:

137264934 137264935 137270056 137277081 137278242 137278466 137278467 137278763 137279038 137279039 137279040 137283676 137287479 137294413 137296691

HCRA:

139441681 139451699 139456808 139456825 139457571

CRG:	105327938 105330883

CANU:

128156904 128163203 128164301 128182706 128183131 128187809 128189638

CVN:	111111333 111111704 111114042 111118814 111120297 111121378 111123853

OED:	125665259 125674210

PMAX:

117322924 117325068 117327667

AIRR:

138310597 138312431 138323481 138323940 138324164 138328755

MMER:

123544854 123550142

RPHI:

132728783 132731949 132734579 132751681 132757721

DPOL:

MAEA:

OBI:

OSN:

LJP:	135471917 135479305

LLON:

135500440

ADF:	107339612 107339613 107348974 107352312

AMIL:

114953865 114961057

PDAM:

113673363 113675665 113685547 113686105

SPIS:

111326811

DGT:

114521989

XEN:	124437402 124438559 124439349 124439368 124442651

HSY:	130614267 130645808

RES:	135682699 135683885 135684679 135694576

» show all

Reference

PMID:1325798

Authors

Pierce KD, Furlong TJ, Selbie LA, Shine J

Title

Molecular cloning and expression of an adenosine A2b receptor from human brain.

Journal

Biochem Biophys Res Commun 187:86-93 (1992)
DOI:10.1016/S0006-291X(05)81462-7

Sequence

[hsa:136]

LinkDB

DBGET integrated database retrieval system