KEGG ORTHOLOGY: K04298

ORTHOLOGY: K04298

Entry

K04298                      KO

Symbol

P2RY12

Name

P2Y purinoceptor 12

Pathway

map04082

Neuroactive ligand signaling

map04148

Efferocytosis

map04611

Platelet activation

Disease

H01235

Bleeding disorder platelet-type

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    K04298  P2RY12; P2Y purinoceptor 12
09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    K04298  P2RY12; P2Y purinoceptor 12
09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    K04298  P2RY12; P2Y purinoceptor 12
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors
    K04298  P2RY12; P2Y purinoceptor 12
G protein-coupled receptors [BR:ko04030]
Rhodopsin family
  Base and nucleoside
   Purine / pyrimidine
    K04298  P2RY12; P2Y purinoceptor 12

Other DBs

GO:

0045028

Genes

HSA:	64805(P2RY12)

PTR:	738917(P2RY12)

PPS:	100981259(P2RY12)

GGO:	101151637(P2RY12)

PON:	100450073(P2RY12)

PPYG:

129032672(P2RY12)

NLE:	100581100(P2RY12)

HMH:	116481163(P2RY12)

SSYN:

129467039(P2RY12)

MCC:	710036(P2RY12)

MCF:	102122720(P2RY12)

MTHB:

126948240

MNI:	105463695(P2RY12)

CSAB:

103241467(P2RY12)

CATY:

105597493(P2RY12)

PANU:

101019577(P2RY12)

TGE:	112618796(P2RY12)

MLEU:

105534085(P2RY12)

RRO:	104667982(P2RY12)

RBB:	108517142(P2RY12)

TFN:	117079963(P2RY12)

PTEH:

111555781(P2RY12)

CANG:

105523914(P2RY12)

CJC:	100396621(P2RY12)

SBQ:	101028678(P2RY12)

CIMI:

108300183(P2RY12)

ANAN:

105706574(P2RY12)

CSYR:

103259815(P2RY12)

MMUR:

105881269(P2RY12)

LCAT:

123630182(P2RY12)

PCOQ:

105809173(P2RY12)

OGA:	100962339(P2RY12)

MMU:	70839(P2ry12)

MCAL:

110290742(P2ry12)

MPAH:

110319875(P2ry12)

RNO:	64803(P2ry12)

MCOC:

116092922(P2ry12)

ANU:	117707099(P2ry12)

ASYL:

127683318(P2ry12)

MUN:	110558724(P2ry12)

CGE:	103163423(P2ry12)

MAUA:

101836729(P2ry12)

PROB:

127216358(P2ry12)

PLEU:

114701965(P2ry12)

MORG:

121452984(P2ry12)

MFOT:

126487451

AAMP:

119826171(P2ry12)

NGI:	103743555(P2ry12)

HGL:	101701294(P2ry12)

CPOC:

100720551(P2ry12)

CCAN:

109699220(P2ry12)

DORD:

105995986(P2ry12)

DSP:	122095198(P2ry12)

DMER:

138804488 138837639

PLOP:

125342549

NCAR:

124992725

MMMA:

107143279(P2ry12)

ITI:	101967917(P2ry12)

OCU:

100345006

OPI:	105942613(P2RY12)

TUP:	106734992(P2RY12)

GVR:	103596144(P2RY12)

CFA:	442958(P2RY12)

CLUD:

112652603(P2RY12)

VVP:	112932780(P2RY12)

VLG:	121478765(P2RY12)

NPO:	129507254(P2RY12)

AML:	100467982(P2RY12)

UMR:	103677869(P2RY12)

UAH:	113254065(P2RY12)

UAR:	123802159(P2RY12)

ELK:

111148951

LLV:

125098899

MPUF:

101684526(P2RY12)

MNP:	132012124(P2RY12)

MLK:	131824982(P2RY12)

NVS:	122908611(P2RY12)

ORO:	101377030(P2RY12)

EJU:	114209004(P2RY12)

ZCA:	113916846(P2RY12)

MLX:	118005258(P2RY12)

NSU:	110576735(P2RY12)

LWW:	102731855(P2RY12)

FCA:	101094044(P2RY12)

PYU:	121033848(P2RY12)

PCOO:

112849538(P2RY12)

PBG:	122491849(P2RY12)

PVIV:

125174989(P2RY12)

LRUF:

124526879

LGF:	123611392(P2RY12)

AJU:

106975200

PTG:	102960449(P2RY12)

PPAD:

109261220(P2RY12)

PUC:

125921922

PLEZ:

122198561(P2RY12)

HHV:	120237620(P2RY12)

BTA:	408007(P2RY12)

BOM:	102279592(P2RY12)

BIU:	109559192(P2RY12)

BBUB:

102409448(P2RY12)

BBIS:

104985288(P2RY12)

CHX:	102191739(P2RY12)

OAS:	101117897(P2RY12)

BTAX:

128043954(P2RY12)

CSUM:

138089471(P2RY12)

ODA:	120858698(P2RY12)

CCAD:

122445037(P2RY12)

MREE:

136173693(P2RY12)

OVR:	110132933(P2RY12)

MBEZ:

129546552(P2RY12)

SSC:	503659(P2RY12)

CFR:	102521426(P2RY12)

CBAI:

105066607(P2RY12)

CDK:	105094705(P2RY12)

VPC:	102536407(P2RY12)

BACU:

103010893(P2RY12)

BMUS:

118894639(P2RY12)

LVE:	103084078(P2RY12)

OOR:	101283256(P2RY12)

LALB:

132520857(P2RY12)

DDP:	132425079(P2RY12)

DLE:	111179314(P2RY12)

PCAD:

102991878(P2RY12)

PSIU:

116752579(P2RY12)

PPHC:

136122241(P2RY12)

NASI:

112415885(P2RY12)

ECB:	100630046(P2RY12)

EPZ:	103551471(P2RY12)

EAI:	106826145(P2RY12)

MYB:	102261747(P2RY12)

MYD:	102766801(P2RY12)

MMYO:

118676497(P2RY12)

MLF:	102427451(P2RY12)

MDT:	132230525(P2RY12)

MYUM:

139003753(P2RY12)

PKL:	118722431(P2RY12)

EFUS:

103302123(P2RY12)

MNA:	107540028(P2RY12)

DRO:	112309959(P2RY12)

SHON:

118997908(P2RY12)

AJM:	119042384(P2RY12)

PDIC:

114490663(P2RY12)

PHAS:

123827023(P2RY12)

MMF:	118617896(P2RY12)

PPAM:

129079931(P2RY12)

HAI:	109392700(P2RY12)

RFQ:	117012252(P2RY12)

PALE:

107196716(P2RY12)

PGIG:

120596606(P2RY12)

PVP:	105301532(P2RY12)

RAY:	107516590(P2RY12)

MJV:	108387338(P2RY12)

TOD:	119257669(P2RY12)

SARA:

101539562(P2RY12)

SFUM:

130030190(P2RY12)

SETR:

126025548(P2RY12)

LAV:	100655569(P2RY12)

TMU:

101341489

ETF:	101649510(P2RY12)

DNM:	101429663(P2RY12)

MDO:	100618708(P2RY12)

GAS:	123242785(P2RY12)

SHR:	100915158(P2RY12)

AFZ:

127552935

PCW:	110204769(P2RY12)

TVP:	118845346(P2RY12)

PBRV:

138174432(P2RY12)

MLAO:

141490785(P2RY12)

OAA:	100682030(P2RY12)

TACU:

119934041(P2RY12)

GGA:	101749756(P2RY12)

PCOC:

116235446(P2RY12)

MGP:	104912737(P2RY12)

CJO:	107318393(P2RY12)

TPAI:

128082832(P2RY12)

LMUT:

125697850(P2RY12)

NMEL:

110398801(P2RY12)

APLA:

101800703(P2RY12)

ACYG:

106047673(P2RY12)

CATA:

118258045(P2RY12)

AFUL:

116492357(P2RY12)

TGU:	101233112(P2RY12)

LSR:	110478353(P2RY12)

SCAN:

103815253(P2RY12)

PMOA:

120504253(P2RY12)

OTC:	121336686(P2RY12)

PRUF:

121353861(P2RY12)

ATRC:

139595201(P2RY12)

GFR:	102044055(P2RY12)

FAB:	101817541(P2RY12)

OMA:	130256911(P2RY12)

PHI:

102111713

PMAJ:

107209016(P2RY12)

CCAE:

111933250(P2RY12)

CCW:	104688100(P2RY12)

CBRC:

103615692(P2RY12)

ACOE:

138114671(P2RY12)

ETL:	114061412(P2RY12)

ZAB:	102065128(P2RY12)

ZLE:	135451894(P2RY12)

ACHL:

103801593(P2RY12)

SVG:	106859154(P2RY12)

HRT:	120757387(P2RY12)

SATI:

136365294(P2RY12)

CCIC:

134047859(P2RY12)

FPG:	101924259(P2RY12)

FCH:	102058760(P2RY12)

CCRI:

104168539(P2RY12)

NNT:	104404893(P2RY12)

SHAB:

115611722(P2RY12)

ACUN:

113483304(P2RY12)

TALA:

104368053(P2RY12)

ACHC:

115346990(P2RY12)

HALD:

104319878(P2RY12)

HLE:	104842517(P2RY12)

AGEN:

126039934

HHAR:

128148802(P2RY12)

GCL:

127019908

CSTI:

104556777(P2RY12)

LDI:	104349188(P2RY12)

MNB:	103773915(P2RY12)

DPUB:

104301943

PPUS:

135187113(P2RY12)

AVIT:

104278848(P2RY12)

BRHI:

104499653(P2RY12)

EGZ:	104122215(P2RY12)

PCRI:

104026210(P2RY12)

PCAO:

104048847(P2RY12)

PADL:

103925270(P2RY12)

AFOR:

103903110(P2RY12)

FGA:	104075953(P2RY12)

GSTE:

104256011(P2RY12)

CBOY:

140654536(P2RY12)

CLV:

102091717

CNIC:

135991225(P2RY12)

MUI:	104537408(P2RY12)

PGUU:

104468773(P2RY12)

PLET:

104615752(P2RY12)

EHS:	104509299(P2RY12)

CMAC:

104483511(P2RY12)

CUCA:

104065241(P2RY12)

TEO:	104373736(P2RY12)

BREG:

104637397(P2RY12)

OHA:	104336548(P2RY12)

ACAR:

104522627(P2RY12)

CPEA:

104395059(P2RY12)

RTD:	128910980(P2RY12)

CRID:

134516835(P2RY12)

LMIC:

141745490(P2RY12)

AAM:	106484183(P2RY12)

AROW:

112965771(P2RY12)

NPD:	112952362(P2RY12)

TGT:	104573740(P2RY12)

DNE:	112981341(P2RY12)

SCAM:

104145038(P2RY12)

ASN:	102377702(P2RY12)

AMJ:	106737330(P2RY12)

CPOO:

109308346(P2RY12)

GGN:	109287891(P2RY12)

PSS:	102462407(P2RY12)

CMY:	102938090(P2RY12)

CCAY:

125642318(P2RY12)

DCC:	119861099(P2RY12)

CPIC:

101946451(P2RY12)

TST:	117882462(P2RY12)

CABI:

116821261(P2RY12)

MRV:	120371513(P2RY12)

ACS:	103278184(p2ry12)

ASAO:

132769848(P2RY12)

PVT:	110073071(P2RY12)

SUND:

121926817(P2RY12)

PBI:	103058646(P2RY12)

PMUR:

107286024(P2RY12)

CTIG:

120314661(P2RY12)

TSR:	106554403(P2RY12)

PGUT:

117678279(P2RY12)

PCAE:

139318400(P2RY12)

APRI:

131200408(P2RY12)

PTEX:

113436906(P2RY12)

NSS:	113410515(P2RY12)

VKO:	123024807(P2RY12)

PMUA:

114597890(P2RY12)

PRAF:

128414666(P2RY12)

ZVI:	118093397(P2RY12)

HCG:	128349480(P2RY12)

GJA:	107117500(P2RY12)

STOW:

125438634(P2RY12)

EMC:	129332621(P2RY12)

XLA:	108717584(p2ry12.S) 495243(p2ry12.L)

XTR:	100493410(p2ry12)

NPR:	108794779(P2RY12)

RTEM:

120936660(P2RY12)

ACAT:

141139669(P2RY12)

BBUF:

120997808(P2RY12)

BGAR:

122933995(P2RY12)

DTC:

141092681

PWL:

138265539

MUO:	115479017(P2RY12)

GSH:	117366530(P2RY12)

DRE:	100149618(p2ry12)

SRX:	107720413 107750125

SANH:

107701293 107703023

SGH:	107551255 107572521

CCAR:

109053554 109081334

CAUA:

113058231 113115433

CGIB:

127972336 128028666

PTET:

122358447(p2ry12)

LROH:

127177759(p2ry12)

GRF:	141285345(p2ry12)

OMC:	131520481(p2ry12)

PPRM:

120464583(p2ry12)

RKG:	130102090(p2ry12)

MAMB:

125249011(p2ry12) 125261553

CIDE:

127496091

CERY:

137004757(p2ry12)

MASI:

127429811

TROS:

130564989(p2ry12)

TDW:	130428562(p2ry12)

MANU:

129437539(p2ry12) 129437540 129437541 129438800

PDAB:

135770288 135770526 135770527 135770529 135771464

IPU:

IFU:

PHYP:

SMEO:

TFD:	113640413(p2ry12)

TVC:	132839655(p2ry12)

CGAR:

128513156(p2ry12)

NGRA:

132871138(p2ry12)

TRN:	134302632(p2ry12)

AMEX:

103047191(p2ry12)

CMAO:

EEE:

CHAR:

SPIL:

ASAD:

TRU:

TFS:

TNG:	GSTEN00014732G001

LCO:

104927652

NCC:	104954469(p2ry12)

TBEN:

117470523(p2ry12)

CGOB:

115017969

PGEO:

117457306(p2ry12)

GACU:

117554854(p2ry12)

ELY:	117260124(p2ry12)

EFO:

125889465

PLEP:

121943263(p2ry12)

SLUC:

116050827(p2ry12)

ECRA:

117941802(p2ry12)

ESP:

116685489

PFLV:

114552711

GAT:	120826865(p2ry12)

PPUG:

119222742

AFB:

129093484

CLUM:

117741521(p2ry12)

PSWI:

130210626(p2ry12)

CANA:

CVE:

MSAM:

SCHU:

CUD:	121524898(p2ry12)

SPUL:

138597148(p2ry12)

LMIX:

132980573(p2ry12)

ALAT:

119031735(p2ry12)

ASTR:

137596885(p2ry12)

MZE:

101467746

ONL:

100692921

OAU:	116323637(p2ry12)

OLA:	101156030(p2ry12)

OML:	112149240(p2ry12)

CSAI:

133442384(p2ry12)

XMA:

XCO:

XHE:

PRET:

PFOR:

PLAI:

PMEI:

GAF:

PPRL:

CVG:

CTUL:

119791882(p2ry12)

GMU:	124884221(p2ry12)

NFU:

107383000

KMR:	108240907(p2ry12)

ALIM:

106519416

NWH:	119410893(p2ry12)

AOCE:

111575845(p2ry12)

EJA:	138196941(p2ry12)

BFRE:

138625497(p2ry12)

MCEP:

125013533

CSEM:

103378104

POV:

109630151

SSEN:

122773075(p2ry12)

SSOE:

131462134

HHIP:

117773026

HSP:	118106151(p2ry12)

PPLT:

128440199(p2ry12)

SMAU:

118298939(p2ry12)

LCF:

SDU:

SLAL:

XGL:

HCQ:

SSCV:

125971824(p2ry12)

SBIA:

133504755(p2ry12)

PEE:	133405476(p2ry12)

PTAO:

133482696(p2ry12)

BPEC:

ENY:

MALB:

BSPL:

SJO:	128360506(p2ry12)

SSCO:

133980505(p2ry12)

GMH:

115561798

SASA:

106581495 106613310

STRU:

115163791 115206867

OTW:	112236583 112265740

OMY:	110503248 110508060

OGO:	123992496 124004969 124030928

ONE:	115117508 115119388

OKI:	109881377 109905891

OKE:	118374805 118394772

OMM:	135546704 135553198

OCLA:

139382664 139385883

SALP:

111972329 112072248

SNH:	120018929 120029016

SFON:

129822412 129831649

CCLU:

121567173 121568308

ELS:

105006525

OEP:	134029073(p2ry12)

SFM:

PKI:

AANG:

AROT:

CCOG:

133108435(p2ry12)

LOC:

102685549

PSPA:

121322607 121326910(p2ry12)

ARUT:

117416664 117423596

PSEX:

120531955(p2ry12)

LCM:	102356751(P2RY12)

CMK:

103184463

RTP:	109915427(p2ry12)

HOC:	132821651 132821653

LERI:

129703368

HAKA:

140725752

» show all

Reference

PMID:11196645

Authors

Hollopeter G, Jantzen HM, Vincent D, Li G, England L, Ramakrishnan V, Yang RB, Nurden P, Nurden A, Julius D, Conley PB

Title

Identification of the platelet ADP receptor targeted by antithrombotic drugs.

Journal

Nature 409:202-7 (2001)
DOI:10.1038/35051599

Sequence

[hsa:64805]

LinkDB

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