KEGG ORTHOLOGY: K04298

ORTHOLOGY: K04298

Entry

K04298                      KO

Symbol

P2RY12

Name

P2Y purinoceptor 12

Pathway

map04148

Efferocytosis

map04611

Platelet activation

Disease

H01235

Bleeding disorder platelet-type

Brite

KEGG Orthology (KO) [BR:ko00001]
09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    K04298  P2RY12; P2Y purinoceptor 12
09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    K04298  P2RY12; P2Y purinoceptor 12
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors
    K04298  P2RY12; P2Y purinoceptor 12
G protein-coupled receptors [BR:ko04030]
Rhodopsin family
  Base and nucleoside
   Purine / pyrimidine
    K04298  P2RY12; P2Y purinoceptor 12

Other DBs

GO:

0045028

Genes

HSA:	64805(P2RY12)

PTR:	738917(P2RY12)

PPS:	100981259(P2RY12)

GGO:	101151637(P2RY12)

PON:	100450073(P2RY12)

PPYG:

129032672(P2RY12)

NLE:	100581100(P2RY12)

HMH:	116481163(P2RY12)

SSYN:

129467039(P2RY12)

MCC:	710036(P2RY12)

MCF:	102122720(P2RY12)

MTHB:

126948240

MNI:	105463695(P2RY12)

CSAB:

103241467(P2RY12)

CATY:

105597493(P2RY12)

PANU:

101019577(P2RY12)

TGE:	112618796(P2RY12)

MLEU:

105534085(P2RY12)

RRO:	104667982(P2RY12)

RBB:	108517142(P2RY12)

TFN:	117079963(P2RY12)

PTEH:

111555781(P2RY12)

CANG:

105523914(P2RY12)

CJC:	100396621(P2RY12)

SBQ:	101028678(P2RY12)

CIMI:

108300183(P2RY12)

ANAN:

105706574(P2RY12)

CSYR:

103259815(P2RY12)

MMUR:

105881269(P2RY12)

LCAT:

123630182(P2RY12)

PCOQ:

105809173(P2RY12)

OGA:	100962339(P2RY12)

MMU:	70839(P2ry12)

MCAL:

110290742(P2ry12)

MPAH:

110319875(P2ry12)

RNO:	64803(P2ry12)

MCOC:

116092922(P2ry12)

ANU:	117707099(P2ry12)

MUN:	110558724(P2ry12)

CGE:	103163423(P2ry12)

MAUA:

101836729(P2ry12)

PROB:

127216358(P2ry12)

PLEU:

114701965(P2ry12)

MORG:

121452984(P2ry12)

MFOT:

126487451

AAMP:

119826171(P2ry12)

NGI:	103743555(P2ry12)

HGL:	101701294(P2ry12)

CPOC:

100720551(P2ry12)

CCAN:

109699220(P2ry12)

DORD:

105995986(P2ry12)

DSP:	122095198(P2ry12)

PLOP:

125342549

NCAR:

124992725

MMMA:

107143279(P2ry12)

OCU:

100345006

OPI:	105942613(P2RY12)

TUP:	106734992(P2RY12)

GVR:	103596144(P2RY12)

CFA:	442958(P2RY12)

CLUD:

112652603(P2RY12)

VVP:	112932780(P2RY12)

VLG:	121478765(P2RY12)

NPO:	129507254(P2RY12)

AML:	100467982(P2RY12)

UMR:	103677869(P2RY12)

UAH:	113254065(P2RY12)

UAR:	123802159(P2RY12)

ELK:

111148951

LLV:

125098899

MPUF:

101684526(P2RY12)

MNP:	132012124(P2RY12)

MLK:	131824982(P2RY12)

NVS:	122908611(P2RY12)

ORO:	101377030(P2RY12)

EJU:	114209004(P2RY12)

ZCA:	113916846(P2RY12)

MLX:	118005258(P2RY12)

NSU:	110576735(P2RY12)

LWW:	102731855(P2RY12)

FCA:	101094044(P2RY12)

PYU:	121033848(P2RY12)

PCOO:

112849538(P2RY12)

PBG:	122491849(P2RY12)

PVIV:

125174989(P2RY12)

LRUF:

124526879

PTG:	102960449(P2RY12)

PPAD:

109261220(P2RY12)

PUC:

125921922

AJU:

106975200

HHV:	120237620(P2RY12)

BTA:	408007(P2RY12)

BOM:	102279592(P2RY12)

BIU:	109559192(P2RY12)

BBUB:

102409448(P2RY12)

BBIS:

104985288(P2RY12)

CHX:	102191739(P2RY12)

OAS:	101117897(P2RY12)

BTAX:

128043954(P2RY12)

ODA:	120858698(P2RY12)

CCAD:

122445037(P2RY12)

MBEZ:

129546552(P2RY12)

SSC:	503659(P2RY12)

CFR:	102521426(P2RY12)

CBAI:

105066607(P2RY12)

CDK:	105094705(P2RY12)

VPC:	102536407(P2RY12)

BACU:

103010893(P2RY12)

BMUS:

118894639(P2RY12)

LVE:	103084078(P2RY12)

OOR:	101283256(P2RY12)

DLE:	111179314(P2RY12)

PCAD:

102991878(P2RY12)

PSIU:

116752579(P2RY12)

NASI:

112415885(P2RY12)

ECB:	100630046(P2RY12)

EPZ:	103551471(P2RY12)

EAI:	106826145(P2RY12)

MYB:	102261747(P2RY12)

MYD:	102766801(P2RY12)

MMYO:

118676497(P2RY12)

MLF:	102427451(P2RY12)

MDT:	132230525(P2RY12)

PKL:	118722431(P2RY12)

EFUS:

103302123(P2RY12)

MNA:	107540028(P2RY12)

DRO:	112309959(P2RY12)

SHON:

118997908(P2RY12)

AJM:	119042384(P2RY12)

PDIC:

114490663(P2RY12)

PHAS:

123827023(P2RY12)

MMF:	118617896(P2RY12)

PPAM:

129079931(P2RY12)

HAI:	109392700(P2RY12)

RFQ:	117012252(P2RY12)

PALE:

107196716(P2RY12)

PGIG:

120596606(P2RY12)

PVP:	105301532(P2RY12)

RAY:	107516590(P2RY12)

MJV:	108387338(P2RY12)

TOD:	119257669(P2RY12)

SARA:

101539562(P2RY12)

SETR:

126025548(P2RY12)

LAV:	100655569(P2RY12)

TMU:

101341489

ETF:	101649510(P2RY12)

DNM:	101429663(P2RY12)

MDO:	100618708(P2RY12)

GAS:	123242785(P2RY12)

SHR:	100915158(P2RY12)

AFZ:

127552935

PCW:	110204769(P2RY12)

TVP:	118845346(P2RY12)

OAA:	100682030(P2RY12)

GGA:	101749756(P2RY12)

PCOC:

116235446(P2RY12)

MGP:	104912737(P2RY12)

CJO:	107318393(P2RY12)

TPAI:

128082832(P2RY12)

LMUT:

125697850(P2RY12)

NMEL:

110398801(P2RY12)

APLA:

101800703(P2RY12)

ACYG:

106047673(P2RY12)

CATA:

118258045(P2RY12)

AFUL:

116492357(P2RY12)

TGU:	101233112(P2RY12)

LSR:	110478353(P2RY12)

SCAN:

103815253(P2RY12)

PMOA:

120504253(P2RY12)

OTC:	121336686(P2RY12)

PRUF:

121353861(P2RY12)

GFR:	102044055(P2RY12)

FAB:	101817541(P2RY12)

OMA:	130256911(P2RY12)

PHI:

102111713

PMAJ:

107209016(P2RY12)

CCAE:

111933250(P2RY12)

CCW:	104688100(P2RY12)

CBRC:

103615692(P2RY12)

ETL:	114061412(P2RY12)

ZAB:	102065128(P2RY12)

ZLE:	135451894(P2RY12)

ACHL:

103801593(P2RY12)

SVG:	106859154(P2RY12)

HRT:	120757387(P2RY12)

SATI:

136365294(P2RY12)

FPG:	101924259(P2RY12)

FCH:	102058760(P2RY12)

CCRI:

104168539(P2RY12)

NNT:	104404893(P2RY12)

SHAB:

115611722(P2RY12)

ACUN:

113483304(P2RY12)

TALA:

104368053(P2RY12)

ACHC:

115346990(P2RY12)

HALD:

104319878(P2RY12)

HLE:	104842517(P2RY12)

AGEN:

126039934

GCL:

127019908

CSTI:

104556777(P2RY12)

LDI:	104349188(P2RY12)

MNB:	103773915(P2RY12)

DPUB:

104301943

AVIT:

104278848(P2RY12)

BRHI:

104499653(P2RY12)

EGZ:	104122215(P2RY12)

PCRI:

104026210(P2RY12)

PCAO:

104048847(P2RY12)

PADL:

103925270(P2RY12)

AFOR:

103903110(P2RY12)

FGA:	104075953(P2RY12)

GSTE:

104256011(P2RY12)

CLV:

102091717

MUI:	104537408(P2RY12)

PGUU:

104468773(P2RY12)

PLET:

104615752(P2RY12)

EHS:	104509299(P2RY12)

CMAC:

104483511(P2RY12)

CUCA:

104065241(P2RY12)

TEO:	104373736(P2RY12)

BREG:

104637397(P2RY12)

OHA:	104336548(P2RY12)

ACAR:

104522627(P2RY12)

CPEA:

104395059(P2RY12)

RTD:	128910980(P2RY12)

AAM:	106484183(P2RY12)

AROW:

112965771(P2RY12)

NPD:	112952362(P2RY12)

TGT:	104573740(P2RY12)

DNE:	112981341(P2RY12)

SCAM:

104145038(P2RY12)

ASN:	102377702(P2RY12)

AMJ:	106737330(P2RY12)

CPOO:

109308346(P2RY12)

GGN:	109287891(P2RY12)

PSS:	102462407(P2RY12)

CMY:	102938090(P2RY12)

CCAY:

125642318(P2RY12)

DCC:	119861099(P2RY12)

CPIC:

101946451(P2RY12)

TST:	117882462(P2RY12)

CABI:

116821261(P2RY12)

MRV:	120371513(P2RY12)

ACS:	103278184(p2ry12)

ASAO:

132769848(P2RY12)

PVT:	110073071(P2RY12)

SUND:

121926817(P2RY12)

PBI:	103058646(P2RY12)

PMUR:

107286024(P2RY12)

CTIG:

120314661(P2RY12)

TSR:	106554403(P2RY12)

PGUT:

117678279(P2RY12)

APRI:

131200408(P2RY12)

PTEX:

113436906(P2RY12)

NSS:	113410515(P2RY12)

VKO:	123024807(P2RY12)

PMUA:

114597890(P2RY12)

PRAF:

128414666(P2RY12)

ZVI:	118093397(P2RY12)

HCG:	128349480(P2RY12)

GJA:	107117500(P2RY12)

STOW:

125438634(P2RY12)

EMC:	129332621(P2RY12)

XLA:	108717584(p2ry12.S) 495243(p2ry12.L)

XTR:	100493410(p2ry12)

NPR:	108794779(P2RY12)

RTEM:

120936660(P2RY12)

BBUF:

120997808(P2RY12)

BGAR:

122933995(P2RY12)

MUO:	115479017(P2RY12)

GSH:	117366530(P2RY12)

DRE:	100149618(p2ry12)

SRX:	107720413 107750125

SANH:

107701293 107703023

SGH:	107551255 107572521

CCAR:

109053554 109081334

CAUA:

113058231 113115433

CGIB:

127972336 128028666

PTET:

122358447(p2ry12)

LROH:

127177759(p2ry12)

OMC:	131520481(p2ry12)

PPRM:

120464583(p2ry12)

RKG:	130102090(p2ry12)

MAMB:

125249011(p2ry12) 125261553

CIDE:

127496091

CERY:

137004757(p2ry12)

MASI:

127429811

TROS:

130564989(p2ry12)

TDW:	130428562(p2ry12)

MANU:

129437302 129437539(p2ry12) 129437540 129437541

IPU:

IFU:

PHYP:

SMEO:

TFD:	113640413(p2ry12)

TVC:	132839655(p2ry12)

TRN:	134302632(p2ry12)

AMEX:

103047191(p2ry12)

CMAO:

EEE:

CHAR:

TRU:

TFS:

TNG:	GSTEN00014732G001

LCO:

104927652

NCC:	104954469(p2ry12)

TBEN:

117470523(p2ry12)

CGOB:

115017969

PGEO:

117457306(p2ry12)

GACU:

117554854(p2ry12)

ELY:	117260124(p2ry12)

EFO:

125889465

PLEP:

121943263(p2ry12)

SLUC:

116050827(p2ry12)

ECRA:

117941802(p2ry12)

ESP:

116685489

PFLV:

114552711

GAT:	120826865(p2ry12)

PPUG:

119222742

AFB:

129093484

CLUM:

117741521(p2ry12)

PSWI:

130210626(p2ry12)

MSAM:

119883445

SCHU:

122878750

CUD:	121524898(p2ry12)

ALAT:

119031735(p2ry12)

MZE:

101467746

ONL:

100692921

OAU:	116323637(p2ry12)

OLA:	101156030(p2ry12)

OML:	112149240(p2ry12)

CSAI:

133442384(p2ry12)

XMA:

XCO:

XHE:

PRET:

PFOR:

PLAI:

PMEI:

GAF:

PPRL:

CVG:

CTUL:

119791882(p2ry12)

GMU:	124884221(p2ry12)

NFU:

107383000

KMR:	108240907(p2ry12)

ALIM:

106519416

NWH:	119410893(p2ry12)

AOCE:

MCEP:

CSEM:

POV:

SSEN:

122773075(p2ry12)

HHIP:

117773026

HSP:	118106151(p2ry12)

PPLT:

128440199(p2ry12)

SMAU:

118298939(p2ry12)

LCF:

SDU:

SLAL:

XGL:

HCQ:

SSCV:

SBIA:

133504755(p2ry12)

PEE:	133405476(p2ry12)

PTAO:

133482696(p2ry12)

BPEC:

110163702

MALB:

109969001

BSPL:

114868557

SJO:	128360506(p2ry12)

SASA:

106581495 106613310

STRU:

115163791 115206867

OTW:	112236583 112265740

OMY:	110503248 110508060

OGO:	123992496 124004969 124030928

ONE:	115117508 115119388

OKI:	109881377 109905891

OKE:	118374805 118394772

SALP:

111972329 112072248

SNH:	120018929 120029016

CCLU:

ELS:

SFM:

PKI:

AANG:

LOC:

PSPA:

121322607 121326910(p2ry12)

ARUT:

117416664 117423596

PSEX:

120531955(p2ry12)

LCM:	102356751(P2RY12)

CMK:

103184463

RTP:	109915427(p2ry12)

HOC:	132821651 132821653

LERI:

129703368

» show all

Reference

PMID:11196645

Authors

Hollopeter G, Jantzen HM, Vincent D, Li G, England L, Ramakrishnan V, Yang RB, Nurden P, Nurden A, Julius D, Conley PB

Title

Identification of the platelet ADP receptor targeted by antithrombotic drugs.

Journal

Nature 409:202-7 (2001)
DOI:10.1038/35051599

Sequence

[hsa:64805]

LinkDB

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