KEGG ORTHOLOGY: K04608

ORTHOLOGY: K04608

Entry

K04608                      KO

Symbol

GRM6

Name

metabotropic glutamate receptor 6

Pathway

map04072

Phospholipase D signaling pathway

map04080

Neuroactive ligand-receptor interaction

map04082

Neuroactive ligand signaling

map04724

Glutamatergic synapse

Disease

H00787

Congenital stationary night blindness

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04072 Phospholipase D signaling pathway
    K04608  GRM6; metabotropic glutamate receptor 6
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    K04608  GRM6; metabotropic glutamate receptor 6
   04082 Neuroactive ligand signaling
    K04608  GRM6; metabotropic glutamate receptor 6
09150 Organismal Systems
  09156 Nervous system
   04724 Glutamatergic synapse
    K04608  GRM6; metabotropic glutamate receptor 6
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins
    K04608  GRM6; metabotropic glutamate receptor 6
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors
    K04608  GRM6; metabotropic glutamate receptor 6
Protein phosphatases and associated proteins [BR:ko01009]
Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     K04608  GRM6; metabotropic glutamate receptor 6
G protein-coupled receptors [BR:ko04030]
Metabotropic glutamate receptor family
  Glutamate (metabotropic)
   K04608  GRM6; metabotropic glutamate receptor 6

Other DBs

GO:

0001642

Genes

HSA:	2916(GRM6)

PTR:	462323(GRM6)

PPS:	100980484(GRM6)

GGO:	101141393(GRM6)

PON:	100447061(GRM6)

PPYG:

129036471(GRM6)

NLE:	100604632(GRM6)

HMH:	116470661(GRM6)

SSYN:

129485922(GRM6)

MCC:	713339(GRM6)

MCF:	102127153(GRM6)

MTHB:

126956891

MNI:	105484014(GRM6)

CSAB:

103245094(GRM6)

CATY:

105590396(GRM6)

PANU:

101013215(GRM6)

TGE:	112626199(GRM6)

MLEU:

105537310(GRM6)

RRO:	104676216(GRM6)

RBB:	108539295(GRM6)

TFN:	117065422(GRM6) 117089792

PTEH:

111527440(GRM6)

CANG:

105524779(GRM6)

CJC:	100395536(GRM6)

SBQ:	101040561(GRM6)

CIMI:

108295084(GRM6)

ANAN:

105716739(GRM6)

MMUR:

105885212(GRM6)

LCAT:

123621820(GRM6)

PCOQ:

105814878(GRM6)

OGA:	100940780(GRM6)

MMU:	108072(Grm6)

MCAL:

110305503(Grm6)

MPAH:

110332056(Grm6)

RNO:	24419(Grm6)

MCOC:

116077303(Grm6)

ANU:	117710166(Grm6)

ASYL:

127695366(Grm6)

MUN:	110559093(Grm6)

CGE:

100768692

MAUA:

101834544(Grm6)

PROB:

127219330(Grm6)

PLEU:

114687572(Grm6)

MORG:

121456673(Grm6)

MFOT:

126511380

AAMP:

119812155(Grm6)

NGI:	103749383(Grm6)

HGL:	101717017(Grm6)

CPOC:

100722389(Grm6)

CCAN:

109688444(Grm6)

DORD:

105996685(Grm6)

DSP:	122115391(Grm6)

PLOP:

125341810(Grm6)

NCAR:

124987179

MMMA:

107159768(Grm6)

ITI:	101957781(Grm6)

OCU:	100009501(GRM6)

OPI:	101520469(GRM6)

TUP:	102486281(GRM6)

GVR:	103604172(GRM6)

CFA:	481452(GRM6)

CLUD:

112659580(GRM6)

VVP:	112932477(GRM6)

VLG:	121495535(GRM6)

NPO:	129495080(GRM6)

AML:	100471025(GRM6)

UMR:	103680010(GRM6)

UAH:	113261566(GRM6)

UAR:	123790601(GRM6)

ELK:

111158901

LLV:

125101005

MPUF:

101679982(GRM6)

MNP:	132028058(GRM6)

MLK:	131832632(GRM6)

NVS:	122915885(GRM6)

ORO:	101381223(GRM6)

EJU:	114200475(GRM6)

ZCA:	113928751(GRM6)

MLX:	118026476(GRM6)

NSU:	110581180(GRM6)

LWW:	102726240(GRM6)

FCA:	101097449(GRM6)

PYU:	121010531(GRM6)

PCOO:

112860990(GRM6)

PBG:	122486097(GRM6)

PVIV:

125174076(GRM6)

LRUF:

124514793

LGF:	123601712(GRM6)

AJU:

106970122

PTG:	102955321(GRM6)

PPAD:

109278954(GRM6)

PUC:

125935371

PLEZ:

122200039(GRM6)

HHV:	120245686(GRM6)

BTA:	529656(GRM6)

BOM:	102285964(GRM6)

BIU:	109560801(GRM6)

BBUB:

102390022(GRM6)

BBIS:

104981759(GRM6)

CHX:	102182961(GRM6)

OAS:	443292(GRM6)

BTAX:

128050369(GRM6)

CSUM:

138085557(GRM6)

ODA:	120864658(GRM6)

CCAD:

122440962(GRM6)

MREE:

136153389(GRM6)

OVR:	110126441(GRM6)

MBEZ:

129558052(GRM6)

SSC:	102162790(GRM6)

CFR:	102507290(GRM6)

CBAI:

105062078(GRM6)

CDK:	105100644(GRM6)

VPC:	102529713(GRM6)

BACU:

103012357(GRM6)

BMUS:

118892567(GRM6)

LVE:	103072025(GRM6)

OOR:	101283631(GRM6)

LALB:

132518445(GRM6)

DLE:	111169285(GRM6)

PCAD:

102990345(GRM6)

PSIU:

116751413(GRM6)

NASI:

112412808(GRM6)

ECB:	100067731(GRM6)

EPZ:	103540009(GRM6)

EAI:	106843704(GRM6)

MYB:	102255799(GRM6)

MYD:	102768204(GRM6)

MMYO:

118658622(GRM6)

MLF:	102436195(GRM6)

MDT:	132234655(GRM6)

MYUM:

139009988(GRM6)

PKL:	118725907(GRM6)

EFUS:

103295019(GRM6)

MNA:	107529861(GRM6)

DRO:	112304982(GRM6)

SHON:

118994083(GRM6)

AJM:	119039544(GRM6)

PDIC:

114515315(GRM6)

PHAS:

123826611(GRM6)

MMF:	118616077(GRM6)

PPAM:

129078584(GRM6)

HAI:	109392750(GRM6)

RFQ:	117016662(GRM6)

PALE:

102894346(GRM6)

PGIG:

120616632(GRM6)

PVP:	105300006(GRM6)

RAY:	107506995(GRM6)

MJV:	108405208(GRM6)

TOD:	119235116(GRM6)

SARA:

101545963(GRM6)

SFUM:

130024581(GRM6)

SETR:

126015861(GRM6)

LAV:	100673918(GRM6)

TMU:

101360965

ETF:	101651715(GRM6)

DNM:	101436023(GRM6)

MDO:	100018484(GRM6)

GAS:

123254047

SHR:	100922771(GRM6)

AFZ:

127543175

PCW:	110201038(GRM6)

TVP:	118832674(GRM6)

PBRV:

138177202(GRM6)

OAA:	100092360(GRM6)

TACU:

TGU:

PMOA:

OTC:

PRUF:

ATRC:

OMA:

PHI:

ACOE:

ZLE:

MMEA:

CCIC:

SHAB:

ACHC:

AGEN:

CPEA:

CRID:

PSS:

CMY:	102936161(GRM6)

CCAY:

125628433(GRM6)

DCC:	119847044(GRM6)

CABI:

116818918

MRV:

120388520

ACS:	100565811(grm6)

ASAO:

132767599

PVT:	110081176(GRM6)

SUND:

121924091(GRM6)

PBI:	103054660(GRM6)

PMUR:

107300070

CTIG:

120306636(GRM6)

TSR:	106549970(GRM6)

PGUT:

APRI:

PTEX:

NSS:

VKO:	123024031(GRM6)

PMUA:

114588092(GRM6)

PRAF:

ZVI:

HCG:

GJA:

STOW:

EMC:

XLA:	108700296(grm8l.S)

XTR:	100489237(grm8l)

NPR:

RTEM:

BBUF:

BGAR:

PWL:

MUO:

GSH:

DRE:	565450(grm6b) 568484(grm6a)

SRX:	107743101 107749460

SANH:

107653428 107674373 107691362

SGH:	107564587 107584919 107597884 107601768

CCAR:

109045602 109070607 109074760 109074776(grm6b)

CAUA:

113073851 113074156 113095919 113107007 113111139

CGIB:

127963002 127968401 128018950 128022296

PTET:

122350325(grm6a) 122354441(grm6b)

LROH:

127169654(grm6a) 127173139(grm6b)

OMC:	131545435(grm6a) 131549446(grm6b)

PPRM:

120475219(grm6a) 120480678(grm6b)

RKG:	130085608(grm6b) 130099552(grm6a)

MAMB:

125256940(grm6b) 125280117(grm6a)

CIDE:

127518052 127522235

CERY:

137021071(grm6b) 137026243(grm6a)

MASI:

127415019 127424610 127426190 127427975

TROS:

130568444(grm6a) 130571176(grm6b)

TDW:	130410228(grm6b) 130440039(grm6a)

MANU:

129414126(grm6a) 129427363(grm6b)

PDAB:

135718888(grm6b) 135730280 135752019

IPU:	100304477(grm6a)

IFU:	128608282(grm6a)

PHYP:

113535151

SMEO:

124400435(grm6a)

TFD:	113645506(grm6a)

TVC:	132853472(grm6a)

CGAR:

128530607(grm6a)

NGRA:

132893368(grm6a)

TRN:	134301518(grm6b) 134318040(grm6a)

AMEX:

103043198(grm6a) 111195348(grm6b)

CMAO:

118799497(grm6b) 118812970(grm6a)

EEE:	113573032 113585833

CHAR:

105898971(grm6a) 105904145

SPIL:

134087722(grm6a) 134092085(grm6b)

TRU:	101062124 101062894

TFS:	130524289(grm6b) 130530293(grm6a)

TNG:	GSTEN00014074G001

LCO:	104922203 104935485

TBEN:

117475678(grm6b)

CGOB:

115008587

PGEO:

117446076(grm6b)

GACU:

117543722(grm6b)

EMAC:

134882761(grm6b)

ELY:	117256884(grm6b) 117257989

EFO:	125892362(grm6a) 125894556(grm6b)

PLEP:

121955611(grm6b) 121965954

SLUC:

116036156(grm6b) 116045463(grm6a)

ECRA:

117942910(grm6b) 117948301

ESP:

116687312

PFLV:

114554505 114558581

GAT:	120829744(grm6a) 120835137(grm6b)

PPUG:

119222840(grm6a) 119229975(grm6b)

AFB:	129091105(grm6a) 129105677(grm6b)

CLUM:

117730755(grm6b) 117734078(grm6a)

PSWI:

130208562(grm6b)

CANA:

137796257(grm6b) 137801187(grm6a)

CVE:	137879446(grm6b) 137888728

MSAM:

119885978(grm6b) 119905522(grm6a)

SCHU:

122883229(grm6a) 122888072(grm6b)

CUD:	121506944(grm6b) 121517986(grm6a)

SPUL:

138605440(grm6b) 138608186(grm6a)

LMIX:

132977696(grm6b) 132990223(grm6a)

ALAT:

119020604(grm6b) 119022952(grm6a)

ASTR:

137595125(grm6b) 137606004(grm6a)

MZE:	101466327 101473297

ONL:	100699011 100702581

OAU:	116314870(grm6b) 116335442(grm6a)

OLA:	101159432 101165214

OML:	112145025(grm6b) 112158907(grm6a)

CSAI:

133448984(grm6b) 133456973(grm6a)

XMA:	102229501 102232221

XCO:	114136118 114140478

XHE:	116711163 116722827

PRET:

PFOR:

PLAI:

PMEI:

GAF:	122833738(grm6b) 122839452(grm6a)

PPRL:

129355374(grm6b)

CVG:	107099186 107100178

CTUL:

119790406(grm6b) 119791964(grm6a)

GMU:	124856803(grm6b) 124872133(grm6a)

NFU:	107385845 107391451

KMR:	108228703(grm6a) 108244402(grm6b)

ALIM:

106522891 106527716

NWH:	119411742 119417413(grm6a)

AOCE:

111573964(grm6b) 111575172(grm6a)

EJA:	138205176(grm6b) 138215545(grm6a)

BFRE:

138629993(grm6b) 138637281(grm6a)

MCEP:

125007237(grm6b)

CSEM:

103386277(grm7)

POV:

109629323

SSEN:

122767985(grm6b) 122777702(grm6a)

SSOE:

131460796(grm6b) 131468677(grm6a)

HHIP:

117761596(grm6b) 117765230(grm6a)

HSP:	118104935(grm6b) 118111599(grm6a)

PPLT:

128442402(grm6a) 128460573(grm6b)

SMAU:

118309188(grm6b) 118316919(grm6a)

LCF:	108885568(grm6b) 108890575(grm6a)

SDU:	111221763 111235416

SLAL:

111653191 111654960

XGL:	120803857(grm6a) 120807579(grm6b)

HCQ:	109510397 109521528

SSCV:

125977186(grm6b) 125988039(grm6a)

SBIA:

133494763 133507287(grm6b)

PEE:	133406747(grm6a) 133408358

PTAO:

133483321(grm6b) 133484592(grm6a)

BPEC:

110170180 110173262

ENY:	140363071(grm6a) 140365479(grm6b)

MALB:

109955960

BSPL:

114855939(grm6b)

SJO:	128356066(grm6b) 128357469(grm6a)

SSCO:

133987232(grm6a) 134005775(grm6b)

GMH:

115557670

SASA:

106565758 106566502 106582870

STRU:

115150852 115168563 115207570

OTW:	112221336(grm6a) 112254365 112262523

OMY:	110491152(grm6a) 110494574(grm6b) 110527890

OGO:	124003660 124031491(grm6b) 124045009(grm6a)

ONE:	115101850 115137322 115143756

OKI:	109869081 109877067 109890943

OKE:	118359566(grm6a) 118388356(grm6b) 118400091

OMM:	135527513(grm6a) 135540205 135542148

OCLA:

139367745 139371272 139413356

SALP:

111970568 111977415

SNH:	120020681(grm6b) 120061661(grm6a) 120065601

CCLU:

121546069(grm6a) 121575021 121578261

ELS:

105031611

OEP:	134019196(grm6a)

SFM:

108934858

PKI:

111856158

AANG:

118207467(grm6a)

AROT:

135235268(grm6a)

CCOG:

133138446(grm6a)

LOC:

102693397

PSPA:

121305462(grm6a) 121328764

ARUT:

117401607 117404384(grm6a)

PSEX:

120542874(grm6a)

LCM:

102353695

HOC:

132814150

LRJ:	133349414(GRM8) 133356572

BFO:

118415375

BBEL:

109476721

AJJ:	139961605 139962838

AFIL:

BCOO:

FAS:

PVUL:

CRG:

PMAX:

NVE:

Reference

PMID:23452348

Authors

Devi S, Markandeya Y, Maddodi N, Dhingra A, Vardi N, Balijepalli RC, Setaluri V

Title

Metabotropic glutamate receptor 6 signaling enhances TRPM1 calcium channel function and increases melanin content in human melanocytes.

Journal

Pigment Cell Melanoma Res 26:348-56 (2013)
DOI:10.1111/pcmr.12083

Reference

PMID:9215706

Authors

Hashimoto T, Inazawa J, Okamoto N, Tagawa Y, Bessho Y, Honda Y, Nakanishi S

Title

The whole nucleotide sequence and chromosomal localization of the gene for human metabotropic glutamate receptor subtype 6.

Journal

Eur J Neurosci 9:1226-35 (1997)
DOI:10.1111/j.1460-9568.1997.tb01477.x

Sequence

[hsa:2916]

LinkDB

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