KEGG ORTHOLOGY: K04609

ORTHOLOGY: K04609

Entry

K04609                      KO

Symbol

GRM7

Name

metabotropic glutamate receptor 7

Pathway

map04072

Phospholipase D signaling pathway

map04080

Neuroactive ligand-receptor interaction

map04082

Neuroactive ligand signaling

map04724

Glutamatergic synapse

Disease

H02705

Neurodevelopmental disorder with glutamatergic synapse dysfunction

H02886

Neurodevelopmental disorder with seizures, hypotonia, and brain imaging abnormalities

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04072 Phospholipase D signaling pathway
    K04609  GRM7; metabotropic glutamate receptor 7
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    K04609  GRM7; metabotropic glutamate receptor 7
   04082 Neuroactive ligand signaling
    K04609  GRM7; metabotropic glutamate receptor 7
09150 Organismal Systems
  09156 Nervous system
   04724 Glutamatergic synapse
    K04609  GRM7; metabotropic glutamate receptor 7
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins
    K04609  GRM7; metabotropic glutamate receptor 7
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors
    K04609  GRM7; metabotropic glutamate receptor 7
Protein phosphatases and associated proteins [BR:ko01009]
Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     K04609  GRM7; metabotropic glutamate receptor 7
G protein-coupled receptors [BR:ko04030]
Metabotropic glutamate receptor family
  Glutamate (metabotropic)
   K04609  GRM7; metabotropic glutamate receptor 7

Other DBs

GO:

0001642

Genes

HSA:	2917(GRM7)

PTR:	460140(GRM7)

PPS:	100976563(GRM7)

GGO:	101123810(GRM7)

PON:	100171884(GRM7)

PPYG:

129033736(GRM7)

NLE:	100589726(GRM7)

HMH:	116466691(GRM7)

SSYN:

129471615(GRM7)

MCC:	702731(GRM7)

MCF:	123566739(GRM7)

MTHB:

126947680

MNI:	105477634(GRM7)

CSAB:

103227955(GRM7)

CATY:

105585735(GRM7)

PANU:

101013875(GRM7)

TGE:	112618588(GRM7)

MLEU:

105554262(GRM7)

RRO:	104667482(GRM7)

RBB:	108530952(GRM7)

TFN:	117083187(GRM7)

PTEH:

111546965(GRM7)

CANG:

105525604(GRM7)

CJC:	100390090(GRM7)

SBQ:	101053518(GRM7)

CIMI:

108285574(GRM7)

ANAN:

105730012(GRM7)

MMUR:

105869387(GRM7)

LCAT:

123623379(GRM7)

PCOQ:

105822285(GRM7)

OGA:	100961816(GRM7)

MMU:	108073(Grm7)

MCAL:

110296186(Grm7)

MPAH:

110315966(Grm7)

RNO:	81672(Grm7)

MCOC:

116099368(Grm7)

ANU:	117715466(Grm7)

ASYL:

127679018(Grm7)

MUN:	110542286(Grm7)

CGE:	100774073(Grm7)

MAUA:

101835553(Grm7)

PROB:

127236172(Grm7)

PLEU:

114689663 119086105(Grm7)

MORG:

121434639(Grm7)

MFOT:

126505546

AAMP:

119806934(Grm7)

NGI:	103751403(Grm7)

HGL:	101711694(Grm7)

CPOC:

100715331(Grm7)

CCAN:

109678978 109678981

DORD:

105981305(Grm7)

DSP:	122108085(Grm7)

PLOP:

125358771(Grm7)

NCAR:

124971238

MMMA:

107150047(Grm7)

ITI:	101974501(Grm7)

OCU:

100346053

OPI:	101525338(GRM7)

TUP:	102478241(GRM7)

GVR:	103590454(GRM7)

CFA:	484674(GRM7)

CLUD:

112662402(GRM7)

VVP:	112913297 112933712(GRM7)

VLG:	121496207(GRM7)

NPO:	129522572(GRM7)

AML:	105240215(GRM7)

UMR:	103669589(GRM7)

UAH:	113256634(GRM7)

UAR:	123799172(GRM7)

ELK:

111144132

LLV:

125109286

MPUF:

101682140(GRM7)

MNP:	132011522(GRM7)

MLK:	131824172(GRM7)

NVS:	122909243(GRM7)

ORO:	101371932(GRM7)

EJU:	114207739(GRM7)

ZCA:	113918279(GRM7)

MLX:	118005836(GRM7)

NSU:	110584756(GRM7)

FCA:	101090088(GRM7)

PYU:	121041315(GRM7)

PCOO:

112858428(GRM7)

PBG:	122487462(GRM7)

PVIV:

125161313(GRM7)

LRUF:

124524491

LGF:	123605923(GRM7)

AJU:

106984177

PPAD:

109254411(GRM7)

PUC:

125930380

PLEZ:

122214606(GRM7)

HHV:	120239098(GRM7)

BTA:	535362(GRM7)

BOM:	102278887(GRM7)

BIU:	109575846 109575847

BBUB:

102392574(GRM7)

BBIS:

104979865(GRM7)

CHX:	102190560(GRM7)

OAS:	443520(GRM7)

BTAX:

128045086(GRM7)

CSUM:

138087167(GRM7)

ODA:	120867648(GRM7)

CCAD:

122424912(GRM7)

MREE:

136167762(GRM7)

OVR:	110151429(GRM7)

MBEZ:

129548043(GRM7)

SSC:	100621119(GRM7)

CFR:	102516607(GRM7)

CBAI:

105068004

CDK:	105093150(GRM7)

VPC:	102532446(GRM7)

BACU:

103012850(GRM7)

BMUS:

118904021(GRM7)

LVE:	103079834 103080976

OOR:	101284337(GRM7)

LALB:

132527837(GRM7)

DLE:	111170773 111171236 111171303

PCAD:

102987044(GRM7)

PSIU:

116762610(GRM7)

NASI:

112396786(GRM7)

ECB:	100052696(GRM7)

EPZ:	103549493(GRM7)

EAI:	106841759(GRM7)

MYB:	102240757(GRM7)

MYD:	102752739(GRM7)

MMYO:

118668018(GRM7)

MLF:	102431837(GRM7)

MDT:	132215128(GRM7)

MYUM:

138992181(GRM7)

PKL:	118715168(GRM7)

EFUS:

103295217(GRM7)

MNA:	107534797(GRM7)

DRO:	112301181(GRM7)

SHON:

118993365(GRM7)

AJM:	119041432(GRM7)

PDIC:

114502121(GRM7)

PHAS:

123814445(GRM7)

MMF:	118633161(GRM7)

PPAM:

129088331(GRM7)

HAI:	109375705 109376395

RFQ:	117037320(GRM7)

PALE:

102878333(GRM7)

PGIG:

120606347

PVP:	105300363(GRM7)

RAY:	107505037(GRM7) 107513317

MJV:	108392464(GRM7)

TOD:	119237543(GRM7)

SARA:

101542612(GRM7)

SFUM:

130037302(GRM7)

SETR:

125998040(GRM7)

LAV:	100664172(GRM7)

TMU:

101343730

ETF:	101646419(GRM7)

DNM:	101431937(GRM7)

MDO:	100013595(GRM7)

GAS:	123230688(GRM7)

SHR:	100921583(GRM7)

AFZ:

127551527

PCW:	110199092(GRM7)

TVP:	118832371(GRM7)

PBRV:

138158095(GRM7)

OAA:	100086700(GRM7)

TACU:

119919831(GRM7)

GGA:	416112(GRM7)

PCOC:

116236662(GRM7)

MGP:	104913208(GRM7)

CJO:	107319945(GRM7)

TPAI:

128078306(GRM7)

LMUT:

125698666(GRM7)

NMEL:

110405083(GRM7)

APLA:

101791637(GRM7)

ACYG:

106036762(GRM7)

CATA:

118248166(GRM7)

AFUL:

116493170(GRM7)

TGU:	100220449(GRM7)

LSR:	110469857(GRM7)

SCAN:

103824151(GRM7)

PMOA:

120514112(GRM7)

OTC:	121347258(GRM7)

PRUF:

121350541(GRM7)

ATRC:

139595728(GRM7)

GFR:	102035073(GRM7)

FAB:	101817877(GRM7)

OMA:	130258461(GRM7)

PHI:	102107228(GRM7)

PMAJ:

107210125(GRM7)

CCAE:

111934917(GRM7)

CCW:	104683518(GRM7)

CBRC:

103616318(GRM7)

ACOE:

138117388(GRM7)

ETL:

114068243

ZAB:	102063490(GRM7)

ZLE:	135453421(GRM7)

SVG:	106850371(GRM7)

MMEA:

130584651

HRT:	120758300(GRM7)

SATI:

136366231(GRM7)

CCIC:

134048753(GRM7)

FPG:	101916947(GRM7)

FCH:	102051550(GRM7)

CCRI:

104166818(GRM7)

NNT:

104400479

SHAB:

115614578(GRM7)

ACUN:

113484789(GRM7)

TALA:

104358813(GRM7)

ACHC:

115333293(GRM7)

HALD:

104322265

HLE:	104833599(GRM7)

AGEN:

126049863

HHAR:

128137263(GRM7)

GCL:

127021577

LDI:	104345825(GRM7)

MNB:

103771378

DPUB:

104296269

PPUS:

135182272(GRM7)

AVIT:

104273081(GRM7)

BRHI:

104501927(GRM7)

EGZ:	104121789(GRM7)

NNI:	104016948(GRM7)

PADL:

103913590(GRM7)

AFOR:

103902578(GRM7)

GSTE:

104255062

CLV:	102085764(GRM7)

MUI:	104537536(GRM7)

PGUU:

104464371

EHS:	104517301(GRM7)

CMAC:

104481615(GRM7)

CUCA:

104063588(GRM7)

BREG:

104634454

OHA:

104339147

CPEA:

104393831(GRM7)

CVF:	104284540(GRM7)

RTD:	128915606(GRM7)

CRID:

134521334(GRM7)

AAM:	106489806(GRM7)

AROW:

112970474(GRM7)

NPD:	112944045(GRM7)

TGT:	104569946(GRM7)

DNE:	112982932(GRM7)

SCAM:

104148111(GRM7)

ASN:	102379275(GRM7) 102380524

AMJ:	102561244(GRM7)

CPOO:

109311148(GRM7)

GGN:	109288943(GRM7)

PSS:	102463673(GRM7)

CMY:	102938629(GRM7)

CCAY:

125639950(GRM7)

DCC:	119859088(GRM7)

CPIC:

101943447(GRM7)

TST:	117880311(GRM7)

CABI:

116827048(GRM7)

MRV:	120368831(GRM7)

ACS:	100567449(grm7)

ASAO:

132769379(GRM7)

PVT:	110077874(GRM7)

SUND:

121923360(GRM7)

PBI:

103052361

PMUR:

107286670

TSR:	106555368 106555929

PGUT:

117673920(GRM7)

APRI:

131192385(GRM7)

PTEX:

113451249(GRM7)

NSS:	113419451(GRM7)

VKO:	123034485(GRM7)

PMUA:

114591805(GRM7)

PRAF:

128408433(GRM7)

ZVI:	118080055 118081600(GRM7)

HCG:	128345060(GRM7)

GJA:	107111687(GRM7)

STOW:

125428215(GRM7)

EMC:	129329070(GRM7)

XLA:	108713576(grm7.L) 108715851(grm7.S)

XTR:	100127664(grm7)

NPR:	108791917(GRM7)

RTEM:

120944888(GRM7)

BBUF:

120979388(GRM7)

BGAR:

122944223(GRM7)

PWL:	138258982(GRM7)

MUO:	115472824(GRM7)

GSH:	117351420(GRM7)

DRE:	100331190(grm7)

SRX:	107726269 107733072 107756932

SANH:

107661916 107691887 107701594

SGH:	107555009 107592838 107592839

CCAR:

CAUA:

CGIB:

PTET:

LROH:

OMC:

RKG:

MAMB:

CIDE:

CERY:

137029018(grm7)

MASI:

TROS:

TDW:

MANU:

PDAB:

135741168(grm7)

IPU:

IFU:

PHYP:

SMEO:

TFD:

TVC:

CGAR:

NGRA:

TRN:	134302116(grm7)

AMEX:

CMAO:

EEE:

CHAR:

SPIL:

134092033(grm7)

TRU:

101073354

TFS:

130529872

TNG:	GSTEN00033208G001

LCO:	104935569 104937783

NCC:	104961964(grm7)

TBEN:

117479602 117482498

CGOB:

115008819 115011220

PGEO:

117449979(grm7)

GACU:

117540771

EMAC:

134870138 134882847(grm7)

ELY:	117257002 117258332

EFO:	125892137 125894638

PLEP:

SLUC:

ECRA:

ESP:

PFLV:

GAT:	120829560 120835416

PPUG:

119222468 119229834(grm7)

AFB:	129099520 129105177

CLUM:

117730698 117734059

PSWI:

130199224

CANA:

137796409(grm7) 137800529

CVE:	137880719(grm7)

MSAM:

119886700 119905386

SCHU:

122883315 122886169

CUD:	121506940 121518216

SPUL:

138589487 138605337(grm7)

LMIX:

132989625

ALAT:

119020742 119023090

ASTR:

137595829 137605713

MZE:	101467503 101484945

ONL:	100700254 100705106

OAU:	116312921 116324769 120435218 120440355

OLA:	101164051 101165481

OML:	112144627 112159110

CSAI:

133448948(grm7) 133457078

XMA:	102219775 102235041

XCO:	114135704 114147374

XHE:	116711019 116711049 116728437

PRET:

PFOR:

PLAI:

PMEI:

GAF:	122824863 122833753

PPRL:

129355142 129356291 129370374

CVG:	107090377 107095454 107103901

CTUL:

119774137 119794301

GMU:	124856655 124872272

NFU:	107384843 107390975

KMR:	108235264 108251226

ALIM:

106523336 106533220 106536518

NWH:	119412886 119417253

AOCE:

111564152 111574196

EJA:	138193523 138214008(grm7)

BFRE:

138630021(grm7) 138636493

MCEP:

125006440 125018835

CSEM:

103385464 103386478

POV:	109635286 109645252 109645760 109648160

SSEN:

122761065 122777820

SSOE:

131461038 131468975

HHIP:

117759040 117761156 117764600

HSP:	118105430 118111447

PPLT:

128442550 128456624

SMAU:

118309605 118317221

LCF:	108884963 108887728 108889527

SDU:	111217300 111219395

SLAL:

111645422 111651790

XGL:	120783473 120803931

HCQ:

109515024

SSCV:

125988215(grm7)

PEE:	133413684(grm7)

PTAO:

133471559(grm7)

BPEC:

110158052 110171149

ENY:	140363272 140365576(grm7)

MALB:

109964648 109966912

BSPL:

114855179 114858455

SJO:	128355634 128356943

SSCO:

133987207(grm7)

GMH:	115549543 115557554

SASA:

106566206 106566674 106571845 106583727 106583731

STRU:

115150001 115166309 115168490 115207272

OTW:	112215712 112222287 112255367 112263258

OMY:	110491138 110493301 110528632 110531945

OGO:	124003943 124025449 124031678 124045026

ONE:

115131823

OKI:	109868959 109879223 109882700 109907718

OKE:	118360272 118361453 118389598 118400637

OMM:	135504678 135527900 135530281 135541323(grm7)

OCLA:

139368853 139369950 139413906 139416253

SALP:

111966180 111970569 112069034 112073180

SNH:	120020184 120059531 120061648 120064874

CCLU:

121538611 121545333 121574703 121577905

ELS:	105007334 105030112

OEP:	134019028 134028077(grm7)

SFM:	108931310 108941929

PKI:	111843627 111855808

AANG:

118211455

AROT:

135235136 135237690(grm7)

CCOG:

133109737 133139600

LOC:	102684792(grm7)

PSPA:

121297749 121329356

ARUT:

117412575 117964123

PSEX:

120540243

LCM:	102361845(GRM7)

CMK:

RTP:

CPLA:

HOC:

LERI:

PMRN:

LRJ:	133342583 133356474 133356475

BBEL:

109481203

SCLV:

120337611

SPU:	581478 582475

LPIC:

AJJ:

APLC:

ARUN:

AAMU:

AFIL:

140147536 140157679 140157716

CLON:

BCOO:

BBIF:

BPYO:

BPAS:

FVI:

NMEA:

CGIG:

PFUC:

VPS:

LHT:

LBD:

CGLO:

FAS:

DAM:	107040564 107043133

CINS:

VCAN:

CCIN:

DSM:

NPT:

NFB:

NLO:

NVG:

AROA:

HVI:

MQU:

FOC:

DMK:

DPZ:

HAME:

LSM:

TCF:

LPOL:

PVUL:

LSAX:

BGT:	106064368 106074148

GAE:	121369092 121388391

HRF:

HRJ:

HASI:

HCRA:

CANU:

CVN:

OED:

PMAX:

MCAF:

DPOL:

127842175 127843155 127845120

ATEN:

116295131 116297229 116301745

MCAZ:

138032414

MFOO:

138004448

DGT:	114516058 114516161 114540699

XEN:	124441668 124445432 124445435 124453738 124459539

HSY:	130628763 130641924 130648804

RES:	135683970 135685721 135688727 135688728 135688766 135689747 135695005

» show all

Reference

PMID:8840028

Authors

Makoff A, Pilling C, Harrington K, Emson P

Title

Human metabotropic glutamate receptor type 7: molecular cloning and mRNA distribution in the CNS.

Journal

Brain Res Mol Brain Res 40:165-70 (1996)
DOI:10.1016/0169-328x(96)00110-6

Sequence

[hsa:2917]

LinkDB

DBGET integrated database retrieval system