KEGG ORTHOLOGY: K04731

ORTHOLOGY: K04731

Entry

K04731                      KO

Symbol

IRAK2

Name

interleukin-1 receptor-associated kinase 2 [EC:2.7.11.1]

Pathway

map04722

Neurotrophin signaling pathway

map05152

Tuberculosis

Brite

KEGG Orthology (KO) [BR:ko00001]
09150 Organismal Systems
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    K04731  IRAK2; interleukin-1 receptor-associated kinase 2
09160 Human Diseases
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    K04731  IRAK2; interleukin-1 receptor-associated kinase 2
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases
    K04731  IRAK2; interleukin-1 receptor-associated kinase 2
Enzymes [BR:ko01000]
2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     K04731  IRAK2; interleukin-1 receptor-associated kinase 2
Protein kinases [BR:ko01001]
Serine/threonine kinases: TKL group
  IRAK family
   K04731  IRAK2; interleukin-1 receptor-associated kinase 2

Genes

HSA:	3656(IRAK2)

PTR:	460165(IRAK2)

PPS:	100986617(IRAK2)

GGO:	101127688(IRAK2)

PON:	100454140(IRAK2)

PPYG:

129033207(IRAK2)

NLE:	100579496(IRAK2)

HMH:	116466544(IRAK2)

SSYN:

129471643(IRAK2)

MCC:	698091(IRAK2)

MCF:	102135140(IRAK2)

MTHB:

126947713

MNI:	105477691(IRAK2)

CSAB:

103228653(IRAK2)

CATY:

105585776(IRAK2)

PANU:

101025226(IRAK2)

TGE:	112618865(IRAK2)

MLEU:

105549539(IRAK2)

RRO:	104667142(IRAK2)

RBB:	108512268(IRAK2)

TFN:	117083241(IRAK2)

PTEH:

111546931(IRAK2)

CANG:

105519079(IRAK2)

CJC:	100403619(IRAK2)

SBQ:	101035769(IRAK2)

CIMI:

108284660(IRAK2)

ANAN:

105731306(IRAK2)

CSYR:

103262037(IRAK2)

MMUR:

105869053(IRAK2)

LCAT:

123623057(IRAK2)

PCOQ:

105812174(IRAK2)

OGA:	100966956(IRAK2)

MMU:	108960(Irak2)

MCAL:

110296422(Irak2) 110302454

MPAH:

110316521(Irak2)

RNO:	362418(Irak2)

MCOC:

116099408(Irak2)

ANU:	117715549(Irak2)

ASYL:

127679055(Irak2)

MUN:	110548940(Irak2)

CGE:	100758629(Irak2)

MAUA:

101830137(Irak2)

PROB:

127236147(Irak2)

PLEU:

114689617(Irak2)

PMAV:

102927384(Irak2)

MORG:

121435844(Irak2)

MFOT:

126505477

AAMP:

119806955(Irak2)

NGI:	103751434(Irak2)

HGL:	101697284(Irak2)

CPOC:

100728945(Irak2)

CCAN:

109688956(Irak2)

DORD:

105981248(Irak2)

DSP:	122108166(Irak2)

DMER:

138822697 138824804

PLOP:

125358785(Irak2)

NCAR:

124971223

MMMA:

107150072(Irak2)

ITI:	101956291(Irak2)

OCU:

103345503

OPI:	101531569(IRAK2)

OCZ:	121166101(IRAK2)

TUP:	102500857(IRAK2)

GVR:

103610945

CFA:	484657(IRAK2)

CLUD:

112661873(IRAK2)

VVP:	112933707(IRAK2)

VLG:	121496058(IRAK2)

NPO:	129522508(IRAK2)

AML:	100468615(IRAK2)

UMR:	103669562(IRAK2)

UAH:	113257163(IRAK2)

UAR:	123799205(IRAK2)

ELK:

111144038

LLV:

125108718

MPUF:

101680607(IRAK2)

MNP:	132009886(IRAK2)

MLK:	131824217(IRAK2)

NVS:	122909211(IRAK2)

ORO:	101369863(IRAK2)

EJU:	114207676(IRAK2)

ZCA:	113917779(IRAK2)

MLX:	118004873(IRAK2)

NSU:	110584816(IRAK2)

LWW:	102739305(IRAK2)

FCA:	101086888(IRAK2)

PYU:	121041269(IRAK2)

PCOO:

112857889(IRAK2)

PBG:	122487497(IRAK2)

PVIV:

125161096(IRAK2)

LRUF:

124523766

LGF:	123605965(IRAK2)

AJU:

106972373

PTG:	102964669(IRAK2)

PPAD:

109254367(IRAK2)

PUC:

125929630

PLEZ:

122203723(IRAK2)

HHV:	120231341(IRAK2)

BTA:	515034(IRAK2)

BOM:	102264912(IRAK2)

BIU:	109576286(IRAK2)

BBUB:

102411331(IRAK2)

BBIS:

104990147(IRAK2)

CHX:	102180544(IRAK2)

OAS:	101122222(IRAK2)

BTAX:

128049655(IRAK2)

CSUM:

138087405(IRAK2)

ODA:	120867721(IRAK2)

CCAD:

122424432(IRAK2)

MREE:

136166624(IRAK2)

OVR:	110133519(IRAK2)

MBEZ:

129548074(IRAK2)

SSC:	106505672(IRAK2)

CFR:	102513370(IRAK2)

CBAI:

105067455(IRAK2)

CDK:	105093117(IRAK2)

VPC:	102526122(IRAK2)

BACU:

103006452(IRAK2)

BMUS:

118903878(IRAK2)

LVE:	103080836(IRAK2)

OOR:	101273127(IRAK2)

LALB:

132526799(IRAK2)

GMF:	115844043(IRAK2)

DDP:	132432508(IRAK2)

DLE:	111169948(IRAK2)

PCAD:

102996764(IRAK2)

PSIU:

116762787(IRAK2)

PPHC:

136129201(IRAK2)

NASI:

112412932(IRAK2)

ECB:	100058093(IRAK2)

EPZ:	103561462(IRAK2)

EAI:	106835624(IRAK2)

MYB:	102262595(IRAK2)

MYD:	102765283(IRAK2)

MMYO:

118668055(IRAK2)

MLF:	102422936(IRAK2)

MDT:	132215380(IRAK2)

MYUM:

139022457(IRAK2)

PKL:	118715199(IRAK2)

EFUS:

103295537(IRAK2)

MNA:	107534744(IRAK2)

DRO:	112301234(IRAK2)

SHON:

118993332(IRAK2)

AJM:	119038337(IRAK2)

PDIC:

114501671(IRAK2)

PHAS:

123814442(IRAK2)

MMF:	118633377(IRAK2)

PPAM:

129087944(IRAK2)

HAI:	109387293(VHL)

RFQ:	117037303(IRAK2)

PALE:

102890828(IRAK2)

PGIG:

120621457(IRAK2)

PVP:	105299033(IRAK2)

RAY:	107498358(IRAK2)

MJV:

108408138

TOD:	119255473(IRAK2)

SARA:

101537853(IRAK2)

SFUM:

130037789(IRAK2)

SETR:

125997926(IRAK2)

LAV:	100658954(IRAK2)

TMU:

101352317

ETF:	101639521(IRAK2)

DNM:	101429286(IRAK2)

MDO:	100024326(IRAK2)

GAS:	123247197(IRAK2)

SHR:	100932591(IRAK2)

AFZ:

127551904

PCW:	110204866(IRAK2)

TVP:	118831401(IRAK2)

PBRV:

138158070(IRAK2)

MLAO:

141496253(IRAK2)

OAA:	100090992(IRAK2)

TACU:

119919442(IRAK2)

GGA:	416118(IRAK2)

PCOC:

116236593(IRAK2)

MGP:	100544771(IRAK2)

CJO:

TPAI:

LMUT:

NMEL:

APLA:

101796415(IRAK2)

ACYG:

106036772(IRAK2)

CATA:

118248075(IRAK2)

AFUL:

116493083

TGU:	100228175(IRAK2)

LSR:	110477116(IRAK2)

SCAN:

103824139(IRAK2)

PMOA:

120495644(IRAK2)

OTC:	121347389(IRAK2)

PRUF:

121352026(IRAK2)

ATRC:

139595718(IRAK2)

GFR:	102031963(IRAK2)

FAB:	101818470(IRAK2)

OMA:	130258100(IRAK2)

PHI:	102106109(IRAK2)

PMAJ:

107210251(IRAK2)

CCAE:

111934911(IRAK2)

CCW:

104683521

CBRC:

103616325

ACOE:

138117334(IRAK2)

ETL:

114067681

ZAB:	102062604(IRAK2)

ZLE:	135453376(IRAK2)

ACHL:

103809418(IRAK2)

SVG:	106851786(IRAK2)

MMEA:

130583620 130585468

HRT:	120758464(IRAK2)

SATI:

136366217(IRAK2)

CCIC:

134048709(IRAK2)

FPG:	101922091(IRAK2)

FCH:

102057703

CCRI:

104165415(IRAK2)

NNT:	104402463(IRAK2)

SHAB:

115614317(IRAK2)

ACUN:

113484726

TALA:

104368614(IRAK2)

ACHC:

115353860(IRAK2)

HALD:

104323924(IRAK2)

HLE:	104833548(IRAK2)

AGEN:

126049960

HHAR:

128136581(IRAK2)

GCL:

127021738

CSTI:

104555690

LDI:	104355005(IRAK2)

MNB:

103773584

DPUB:

104303438

PPUS:

135182260(IRAK2)

AVIT:

104267111

BRHI:

104493751(IRAK2)

EGZ:	104121773(IRAK2)

NNI:	104016955(IRAK2)

PCRI:

104038602

PCAO:

104047457

PADL:

103913595(IRAK2)

AFOR:

103902654(IRAK2)

FGA:	104080625(IRAK2)

CBOR:

142086063(IRAK2)

GSTE:

104257231(IRAK2)

CBOY:

140657880(IRAK2)

MAME:

142415769(IRAK2)

CLV:	102086676(IRAK2)

CNIC:

135992982(IRAK2)

MUI:

104536049

PGUU:

104470927(IRAK2)

PLET:

104614733

EHS:	104514246(IRAK2)

CMAC:

104479489

CUCA:

104063593(IRAK2)

TEO:	104382308(IRAK2)

BREG:

OHA:

ACAR:

CPEA:

CVF:	104284524(IRAK2)

RTD:	128915569(IRAK2)

CRID:

134521566(IRAK2)

LMIC:

141749440(IRAK2)

AAM:	106494624(IRAK2)

AROW:

112970512(IRAK2)

NPD:	112958659(IRAK2)

TGT:	104571462(IRAK2)

DNE:	112982920(IRAK2)

SCAM:

104148136(IRAK2)

ASN:	102373890(IRAK2)

AMJ:	102557926(IRAK2)

CPOO:

109311133(IRAK2)

GGN:	109288930(IRAK2)

PSS:	102445924(IRAK2)

CIZ:	142019024(IRAK2)

CMY:	102930051(IRAK2)

CCAY:

125640132(IRAK2)

DCC:	119859187(IRAK2)

CPIC:

101936513(IRAK2)

TST:	117879983(IRAK2)

CABI:

116827060(IRAK2)

MRV:	120409379(IRAK2)

ACS:	100560723(irak2)

ASAO:

132769367(IRAK2)

PVT:	110077870(IRAK2)

SUND:

121922871(IRAK2)

PBI:	103052971(IRAK2)

PMUR:

107297847(IRAK2) 107300948

CTIG:

120319525(IRAK2)

TSR:	106543211(IRAK2)

PGUT:

117673908(IRAK2)

PCAE:

139309503(IRAK2)

APRI:

131190832(IRAK2)

PTEX:

113451387(IRAK2)

NSS:	113419335(IRAK2)

VKO:	123034130(IRAK2)

PMUA:

114591792(IRAK2)

PRAF:

128408416(IRAK2)

ZVI:	118080789(IRAK2)

HCG:	128347829(IRAK2)

GJA:	107122201(IRAK2)

STOW:

125430105(IRAK2)

EMC:	129327472(IRAK2)

XLA:	108715855(vhl.S) 379176(irak2.L)

XTR:	493227(irak2)

NPR:	108786038(IRAK2)

RTEM:

120946165

ACAT:

141102761(IRAK2)

PADS:

140336988(IRAK2)

BBUF:

120978598(IRAK2)

BGAR:

122943204(IRAK2)

DTC:	141088778(IRAK2) 141088779

PWL:	138258970(IRAK2)

MUO:

115472469

PSPA:

121298250

ARUT:

117411730

LCM:	102363245(IRAK2)

CPLA:

CPUN:

SCAU:

Reference

PMID:12620219

Authors

Janssens S, Beyaert R

Title

Functional diversity and regulation of different interleukin-1 receptor-associated kinase (IRAK) family members.

Journal

Mol Cell 11:293-302 (2003)
DOI:10.1016/S1097-2765(03)00053-4

LinkDB

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