KEGG ORTHOLOGY: K04993

ORTHOLOGY: K04993

Entry

K04993                      KO

Symbol

MCOLN2, TRPML2

Name

mucolipin 2

Pathway

map04020

Calcium signaling pathway

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04020 Calcium signaling pathway
    K04993  MCOLN2, TRPML2; mucolipin 2
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels
    K04993  MCOLN2, TRPML2; mucolipin 2
Ion channels [BR:ko04040]
Voltage-gated cation channels
  Transient receptor potential channel (TRP)
   K04993  MCOLN2, TRPML2; mucolipin 2

Other DBs

GO:

0005262

TC:

1.A.5.3.3

Genes

HSA:	255231(MCOLN2)

PTR:	456981(MCOLN2)

PPS:	100975357(MCOLN2)

GGO:	101142430(MCOLN2)

PON:	100451398(MCOLN2)

PPYG:

129040193(MCOLN2)

NLE:	100590828(MCOLN2)

HMH:	116469832(MCOLN2)

SSYN:

134733703(MCOLN2)

MCC:	710909(MCOLN2)

MCF:	102138553(MCOLN2)

MTHB:

126963657

MNI:	105482758(MCOLN2)

CSAB:

103224523(MCOLN2)

CATY:

105593578(MCOLN2)

PANU:

101002052(MCOLN2)

TGE:	112634649(MCOLN2)

MLEU:

105541200(MCOLN2)

RRO:	104677502(MCOLN2)

RBB:	108514811(MCOLN2)

TFN:	117092180(MCOLN2)

PTEH:

111540254(MCOLN2)

CANG:

105521795(MCOLN2)

CJC:	100412022(MCOLN2)

SBQ:	101044222(MCOLN2)

CIMI:

108283474(MCOLN2)

ANAN:

105710156(MCOLN2)

CSYR:

103267192(MCOLN2)

MMUR:

105861802(MCOLN2)

LCAT:

123635464(MCOLN2)

PCOQ:

105823820(MCOLN2)

OGA:	100955936(MCOLN2)

MMU:	68279(Mcoln2)

MCAL:

110291215(Mcoln2)

MPAH:

110320203(Mcoln2)

RNO:	292168(Mcoln2)

MCOC:

116093915(Mcoln2)

ANU:	117707131(Mcoln2)

ASYL:

127682581(Mcoln2)

MUN:	110558303(Mcoln2)

CGE:	100759844(Mcoln2)

MAUA:

101843249(Mcoln2)

PROB:

127229893(Mcoln2)

PLEU:

114698247(Mcoln2)

PMAV:

102916103(Mcoln2)

MORG:

121448452(Mcoln2)

MFOT:

126512435

AAMP:

119801097(Mcoln2)

NGI:	103728105(Mcoln2)

HGL:	101715874(Mcoln2)

CPOC:

100730589(Mcoln2)

CCAN:

109699397(Mcoln2)

DORD:

105987099(Mcoln2)

DSP:	122106988(Mcoln2)

DMER:

138817061(Mcoln2)

PLOP:

125355350(Mcoln2)

NCAR:

124989078

MMMA:

107158283(Mcoln2)

ITI:	101970570(Mcoln2)

OCU:

100340674

OPI:	101532440(MCOLN2)

OCZ:	121161075(MCOLN2)

TUP:	102494757(MCOLN2)

GVR:	103599683(MCOLN2)

CFA:	490186(MCOLN2)

CLUD:

112640968(MCOLN2)

VVP:	112924437(MCOLN2)

VLG:	121487570(MCOLN2)

NPO:	129519140(MCOLN2)

AML:	100472508(MCOLN2)

UMR:	103662964(MCOLN2)

UAH:	113254475(MCOLN2)

UAR:	123795264(MCOLN2)

ELK:

111143119

LLV:

125098422

MPUF:

101685390(MCOLN2)

MNP:	132001073(MCOLN2)

MLK:	131809112(MCOLN2)

NVS:	122900139(MCOLN2)

ORO:	101362883(MCOLN2)

EJU:	114208482(MCOLN2)

ZCA:	113929235(MCOLN2)

MLX:	118019214(MCOLN2)

NSU:	110580409(MCOLN2)

LWW:

102739211

FCA:	101098395(MCOLN2)

PYU:	121027392(MCOLN2)

PCOO:

112864176(MCOLN2)

PBG:	122480712(MCOLN2)

PVIV:

125173037(MCOLN2)

LRUF:

124515179

LGF:	123598149(MCOLN2)

AJU:

106973341

PTG:	102967963(MCOLN2)

PPAD:

109246192(MCOLN2)

PUC:

125913379

PLEZ:

122227744(MCOLN2)

HHV:	120241644(MCOLN2)

BTA:	532671(MCOLN2)

BOM:	102268465(MCOLN2)

BIU:	109556125(MCOLN2)

BBUB:

102415957(MCOLN2)

BBIS:

105003265(MCOLN2)

CHX:	102186546(MCOLN2)

OAS:	101111406(MCOLN2)

BTAX:

128044454(MCOLN2)

CSUM:

138070306(MCOLN2)

ODA:	120856936(MCOLN2)

CCAD:

122436758(MCOLN2)

MREE:

136149594(MCOLN2)

OVR:	110135930(MCOLN2)

MBEZ:

129541596(MCOLN2)

SSC:	100522324(MCOLN2)

CFR:	102524376(MCOLN2)

CBAI:

105075486(MCOLN2)

CDK:	105095048(MCOLN2)

VPC:	102525451(MCOLN2)

BACU:

103013415(MCOLN2)

BMUS:

118880154(MCOLN2)

LVE:	103073309(MCOLN2)

OOR:	101278513(MCOLN2)

LALB:

132516102(MCOLN2)

GMF:	115858314(MCOLN2)

DDP:	132433604(MCOLN2)

DLE:	111178369(MCOLN2)

PCAD:

102995231(MCOLN2)

PSIU:

116763995(MCOLN2)

PPHC:

136120368(MCOLN2)

NASI:

112415084(MCOLN2)

ECB:	100052719(MCOLN2)

EPZ:	103562993(MCOLN2)

EAI:	106824030(MCOLN2)

MYB:	102242778(MCOLN2)

MYD:	102753649(MCOLN2)

MMYO:

118676986(MCOLN2)

MLF:	102417360(MCOLN2)

MDT:	132230889(MCOLN2)

MYUM:

139003507(MCOLN2)

PKL:	118723966(MCOLN2)

EFUS:

103284275(MCOLN2)

MNA:	107543174(MCOLN2)

DRO:	112309255(MCOLN2)

SHON:

118997360(MCOLN2)

AJM:	119062883(MCOLN2)

PDIC:

114497202(MCOLN2)

PHAS:

123816462(MCOLN2)

MMF:	118626305(MCOLN2)

PPAM:

129065582(MCOLN2)

HAI:	109372907(MCOLN2)

RFQ:	117027821(MCOLN2)

PALE:

102891479(MCOLN2)

PGIG:

120583283(MCOLN2)

PVP:	105289074(MCOLN2)

RAY:	107511576(MCOLN2)

MJV:	108403810(MCOLN2)

TOD:	119236226(MCOLN2)

SARA:

101538067(MCOLN2)

SFUM:

130031870(MCOLN2)

SETR:

126005929(MCOLN2)

LAV:	100667025(MCOLN2)

TMU:

101358361

ETF:	101644103(MCOLN2)

DNM:	101423379(MCOLN2)

MDO:	100012328(MCOLN2)

GAS:	123244951(MCOLN2)

SHR:	100932791(MCOLN2)

AFZ:

127563034

PCW:	110209938(MCOLN2)

TVP:	118845368(MCOLN2)

PBRV:

138166170(MCOLN2)

MLAO:

141512672(MCOLN2)

OAA:	100079299(MCOLN2)

TACU:

119927379(MCOLN2)

GGA:	424531(MCOLN2)

PCOC:

116233258(MCOLN2)

MGP:	100550399(MCOLN2)

CJO:	107317570(MCOLN2)

TPAI:

128072486(MCOLN2)

LMUT:

125693796(MCOLN2)

NMEL:

110391061(MCOLN2)

APLA:

101794497(MCOLN2)

ACYG:

106034106(MCOLN2)

CATA:

118243329(MCOLN2)

AFUL:

116492228(MCOLN2)

TGU:	100230863(MCOLN2)

LSR:

110470390

SCAN:

103814916(MCOLN2)

PMOA:

120510882(MCOLN2)

OTC:	121345058(MCOLN2)

PRUF:

121362002(MCOLN2)

ATRC:

139594373(MCOLN2)

GFR:	102041564(MCOLN2)

FAB:	101808477(MCOLN2)

OMA:	130256158(MCOLN2)

PHI:	102110962(MCOLN2)

PMAJ:

107208286(MCOLN2)

CCAE:

111932848(MCOLN2)

CCW:	104695308(MCOLN2)

CBRC:

103612618(MCOLN2)

ACOE:

138113986(MCOLN2)

ETL:	114057100(MCOLN2)

ZAB:	102066582(MCOLN2)

ZLE:	135450935(MCOLN2)

ACHL:

103807997(MCOLN2)

SVG:	106857514(MCOLN2)

MMEA:

130578505(MCOLN2)

HRT:	120756689(MCOLN2)

SATI:

136364938(MCOLN2)

CCIC:

134046526(MCOLN2)

FPG:	101922780(MCOLN2)

FCH:	102053725(MCOLN2)

CCRI:

104164015(MCOLN2)

NNT:	104408213(MCOLN2)

SHAB:

115611826(MCOLN2)

ACUN:

113482963(MCOLN2)

TALA:

104361950(MCOLN2)

ACHC:

115349360(MCOLN2)

HALD:

104314675(MCOLN2)

HLE:	104841121(MCOLN2)

AGEN:

126042134

HHAR:

128147983(MCOLN2)

GCL:

127019177

CSTI:

104559274(MCOLN2)

LDI:	104353291(MCOLN2)

MNB:	103778661(MCOLN2)

DPUB:

104300095(MCOLN2)

PPUS:

135177630(MCOLN2)

AVIT:

104268069(MCOLN2)

BRHI:

104495860(MCOLN2)

EGZ:	104122896(MCOLN2)

NNI:	104015470(MCOLN2)

PCRI:

104024879(MCOLN2)

PCAO:

104049168(MCOLN2)

PADL:

103925142(MCOLN2)

AFOR:

103894643(MCOLN2)

FGA:	104079184(MCOLN2)

CBOR:

142084915(MCOLN2)

GSTE:

104251202(MCOLN2)

CBOY:

140654068(MCOLN2)

MAME:

142412744(MCOLN2)

CLV:	102095775(MCOLN2)

CNIC:

136001760(MCOLN2)

MUI:	104544181(MCOLN2)

PGUU:

104458490(MCOLN2)

PLET:

104618092(MCOLN2)

EHS:	104503685(MCOLN2)

CMAC:

104473874(MCOLN2)

CUCA:

104055202(MCOLN2)

TEO:	104374643(MCOLN2)

BREG:

104629970(MCOLN2)

OHA:	104338837(MCOLN2)

ACAR:

104518474(MCOLN2)

CPEA:

104396732(MCOLN2)

CVF:	104286152(MCOLN2)

RTD:	128913896(MCOLN2)

CRID:

134519916(MCOLN2)

LMIC:

141747515(MCOLN2)

AAM:	106499645(MCOLN2)

AROW:

112961915(MCOLN2)

NPD:	112946172(MCOLN2)

TGT:	104565317(MCOLN2)

DNE:	112993156(MCOLN2)

ASN:	102369169(MCOLN2)

AMJ:	106737138(MCOLN2)

CPOO:

109307336(MCOLN2)

GGN:	109286796(MCOLN2)

PSS:	102450859(MCOLN2)

CIZ:	142017579(MCOLN2)

CMY:	102944859(MCOLN2)

CCAY:

125641702(MCOLN2)

DCC:	119860673(MCOLN2)

CPIC:

101939449(MCOLN2)

TST:	117882026(MCOLN2)

CABI:

116835750(MCOLN2)

MRV:	120370709(MCOLN2)

ACS:	100554755(mcoln2)

ASAO:

132774092(MCOLN2)

PVT:	110079747(MCOLN2)

SUND:

121928024

PBI:	103061165(MCOLN2)

PMUR:

107285254(MCOLN2)

CTIG:

120297864(MCOLN2)

TSR:	106538164(MCOLN2)

PGUT:

117677139(MCOLN2)

PCAE:

139313936(MCOLN2)

APRI:

131194835(MCOLN2)

PTEX:

113436078(MCOLN2)

NSS:	113427690 113427692

VKO:	123024547(MCOLN2)

PMUA:

114598802(MCOLN2)

PRAF:

128415560(MCOLN2)

ZVI:	118088921(MCOLN2)

HCG:	128322083(MCOLN2)

GJA:	107109797(MCOLN2)

STOW:

125433905(MCOLN2)

EMC:	129330582(MCOLN2)

XLA:	432202(mcoln2.L)

XTR:	100379826(mcoln2)

NPR:	108791378(MCOLN2)

RTEM:

120945968(MCOLN2)

ACAT:

141103721(MCOLN2)

PADS:

140336456(MCOLN2)

BBUF:

120979273(MCOLN2)

BGAR:

122943142(MCOLN2)

DTC:	141048850(MCOLN2)

PWL:	138293196(MCOLN2)

MUO:	115471781(MCOLN2)

GSH:	117346875(MCOLN2)

DRE:	394123(mcoln2)

SRX:	107715711 107741530

SANH:

107655403 107664794

SGH:	107563519 107577489

CCAR:

109071021 109082981

CAUA:

113039921(mcoln2)

PTET:

122327189(mcoln2)

LROH:

127153760(mcoln2)

GRF:	141338252(mcoln2)

OMC:	131530025(mcoln2)

PPRM:

120477200 120477211

MAMB:

125252726(mcoln2)

CIDE:

127520404

CERY:

137027805(mcoln2)

MASI:

127438263

TROS:

130548957(mcoln2)

TDW:	130429880(mcoln2)

MANU:

129452805(mcoln2)

PDAB:

135740959(mcoln2)

IPU:	108271039(mcoln2)

IFU:	128613596(mcoln2)

PHYP:

113536545

SMEO:

124390858(mcoln2)

TFD:	113658954(mcoln2)

TVC:	132850159(mcoln2)

CGAR:

128543331(mcoln2)

NGRA:

132898949(mcoln2)

TRN:	134331153(mcoln2)

AMEX:

103032784(mcoln2) 125782224

CMAO:

118819572(mcoln2)

EEE:	113586109(mcoln2)

CHAR:

105898278(mcoln2)

SPIL:

134102125(mcoln2)

ASAD:

121678371(mcoln2)

TRU:	101073403(mcoln2)

TFS:	130528138(mcoln2)

TNG:	GSTEN00028939G001

LCO:	104931931(mcoln2)

NCC:

104962631

TBEN:

117495774(mcoln2)

CGOB:

115006813(mcoln2)

PGEO:

117445420(mcoln2)

GACU:

117555209(mcoln2)

ELY:	117253887(mcoln2)

EFO:	125896078(mcoln2)

PLEP:

121966227(mcoln2)

SLUC:

116055420(mcoln2)

ECRA:

117950649(mcoln2)

ESP:	116695943(mcoln2)

PFLV:

114561860(mcoln2)

GAT:	120823952(mcoln2)

PPUG:

119217050(mcoln2)

AFB:	129094546(mcoln2)

CLUM:

117729289(mcoln2)

PSWI:

130193840(mcoln2)

CANA:

137794735(mcoln2)

CVE:	137870306(mcoln2)

MSAM:

119900645(mcoln2)

SCHU:

122877877(mcoln2)

CUD:	121511883(mcoln2)

SPUL:

138607560(mcoln2)

LMIX:

132964410(mcoln2)

HTC:	141789138(mcoln2)

ALAT:

119028165(mcoln2)

ASTR:

137599298(mcoln2)

MZE:	101478611(mcoln2)

ONL:	100697896(mcoln2)

OAU:	116333086(mcoln2)

OLA:	101158932(mcoln2)

OML:	112150855(mcoln2)

CSAI:

133458470(mcoln2)

XMA:	102221375(mcoln2)

XCO:	114150780(mcoln2)

XHE:

116726331

PRET:

103464189

PFOR:

103130984(mcoln2)

PLAI:

106959875(mcoln2)

PMEI:

106930015(mcoln2)

GAF:	122838680(mcoln2)

PPRL:

129372812(mcoln2)

CVG:	107087210(mcoln2)

CTUL:

119774583(mcoln2)

GMU:	124874479(mcoln2)

NFU:

107392692

KMR:	108230642(mcoln2)

ALIM:

106511455(mcoln2)

NWH:	119407785(mcoln2)

AOCE:

111564518 129347268(mcoln2)

EJA:	138198553(mcoln2)

BFRE:

138618770(mcoln2)

MCEP:

125009349(mcoln2)

CSEM:

103393136

POV:	109625737(mcoln2)

SSEN:

122780793(mcoln2)

SSOE:

131465601(mcoln2)

HHIP:

117759917(mcoln2)

HSP:	118121037(mcoln2)

PPLT:

128448705(mcoln2)

SMAU:

118318741

LCF:

108881287

SDU:	111231626(mcoln2)

SLAL:

111650216(mcoln2)

XGL:	120790487(mcoln2)

HCQ:	109522045(mcoln2)

SSCV:

125969572(mcoln2)

SBIA:

133503173(mcoln2)

PEE:	133406469(mcoln2)

PTAO:

133480937(mcoln2)

BPEC:

110160078(mcoln2)

ENY:	140353582(mcoln2)

MALB:

109958220(mcoln2)

BSPL:

114854445(mcoln2)

SJO:	128361366(mcoln2)

SSCO:

133984277(mcoln2)

TTY:	137187729(mcoln2)

GMH:	115555620(mcoln2)

SASA:

106613436(mcoln2)

STRU:

115157923(mcoln2)

OTW:	112217420(mcoln2)

OMY:	110521962(mcoln2)

OGO:	123994955(mcoln2)

ONE:	115139551(mcoln2)

OKI:	109866719(mcoln2)

OKE:	118386767(mcoln2)

OMM:	135557357(mcoln2)

OCLA:

139406904

SALP:

111962952

SNH:	120054586(mcoln2)

SFON:

129811121(mcoln2)

CCLU:

121533789(mcoln2)

OEP:	134011253(mcoln2)

SFM:	108935029(mcoln2)

PKI:	111847627(mcoln2)

AANG:

118225853(mcoln2)

AROT:

135253756(mcoln2)

CCOG:

133127194(mcoln2)

LOC:	102692219(mcoln2)

PSPA:

121331257(mcoln2)

ARUT:

117402584(mcoln2)

LCM:	102366778(MCOLN2)

CMK:	103174697(mcoln2)

RTP:

CPLA:

CPUN:

HOC:

SCAU:

DPOL:

HSY:

Reference

PMID:12403827

Authors

Di Palma F, Belyantseva IA, Kim HJ, Vogt TF, Kachar B, Noben-Trauth K

Title

Mutations in Mcoln3 associated with deafness and pigmentation defects in varitint-waddler (Va) mice.

Journal

Proc Natl Acad Sci U S A 99:14994-9 (2002)
DOI:10.1073/pnas.222425399

Sequence

[mmu:68279]

LinkDB

DBGET integrated database retrieval system