KEGG ORTHOLOGY: K05003

ORTHOLOGY: K05003

Entry

K05003                      KO

Symbol

KCNJ10, KIR4.1

Name

potassium inwardly-rectifying channel subfamily J member 10

Pathway

map04971

Gastric acid secretion

map05016

Huntington disease

Disease

H00605

Deafness, autosomal recessive

H00803

Seizures-sensorineural deafness-ataxia-mental retardation-electrolyte imbalance (SESAME)

Brite

KEGG Orthology (KO) [BR:ko00001]
09150 Organismal Systems
  09154 Digestive system
   04971 Gastric acid secretion
    K05003  KCNJ10, KIR4.1; potassium inwardly-rectifying channel subfamily J member 10
09160 Human Diseases
  09164 Neurodegenerative disease
   05016 Huntington disease
    K05003  KCNJ10, KIR4.1; potassium inwardly-rectifying channel subfamily J member 10
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels
    K05003  KCNJ10, KIR4.1; potassium inwardly-rectifying channel subfamily J member 10
Ion channels [BR:ko04040]
Voltage-gated cation channels
  Potassium channel, inwardly-rectifying (Kir)
   K05003  KCNJ10, KIR4.1; potassium inwardly-rectifying channel subfamily J member 10

Other DBs

GO:

0015272

TC:	1.A.2.1.16

Genes

HSA:	3766(KCNJ10)

PTR:	457431(KCNJ10)

PPS:	100977423(KCNJ10)

GGO:	101130920(KCNJ10)

PON:	100442831(KCNJ10)

PPYG:

129019301(KCNJ10)

NLE:	100585457(KCNJ10)

HMH:	116469219(KCNJ10)

SSYN:

134733968(KCNJ10)

MCC:	720180(KCNJ10)

MCF:	102146220(KCNJ10)

MTHB:

126936020

MNI:	105498161(KCNJ10)

CSAB:

103223738(KCNJ10)

CATY:

105589288(KCNJ10)

PANU:

101022028(KCNJ10)

TGE:	112611281(KCNJ10)

MLEU:

105532280(KCNJ10)

RRO:	104660409(KCNJ10)

RBB:	108524044(KCNJ10)

TFN:	117074034(KCNJ10)

PTEH:

111543864(KCNJ10)

CANG:

105522640(KCNJ10)

CJC:	100404492(KCNJ10)

SBQ:	101030465(KCNJ10)

CIMI:

108286042(KCNJ10)

ANAN:

105715367(KCNJ10)

CSYR:

103261103(KCNJ10)

MMUR:

105862698(KCNJ10)

LCAT:

123635179(KCNJ10)

ERUF:

138389848(KCNJ10)

PCOQ:

105824433(KCNJ10)

OGA:	100955043(KCNJ10)

MMU:	16513(Kcnj10)

MCAL:

110302294(Kcnj10)

MPAH:

110322293(Kcnj10)

RNO:	29718(Kcnj10)

MCOC:

116103723(Kcnj10)

ANU:	117721454(Kcnj10)

ASYL:

127697603(Kcnj10)

MMIU:

308430987(KCNJ10)

MUN:	110556709(Kcnj10)

CGE:	100764542(Kcnj10)

MAUA:

101829361(Kcnj10)

PROB:

127223614(Kcnj10)

PLEU:

114690689(Kcnj10)

PMAV:

102903453(Kcnj10)

MORG:

121442057(Kcnj10)

MFOT:

126502199

AAMP:

119827537(Kcnj10)

CNL:	130875221(Kcnj10)

NGI:	103740233(Kcnj10)

HGL:	101724136(Kcnj10)

CPOC:

100728962(Kcnj10)

CCAN:

109690081(Kcnj10)

DORD:

105996463(Kcnj10)

DSP:	122109628(Kcnj10)

DMER:

138812245(Kcnj10)

PLOP:

125359278(Kcnj10)

NCAR:

124966221

SVUL:

306643528(KCNJ10)

MMMA:

107147512(Kcnj10)

ITI:	101967430(Kcnj10)

SCIL:

308657119(KCNJ10)

MAVE:

308260955(KCNJ10)

OCU:	100008597(KCNJ10)

OPI:	101528717(KCNJ10)

OCZ:	121171623(KCNJ10)

TUP:	102485474(KCNJ10)

GVR:	103587953(KCNJ10)

CFA:	488635(KCNJ10)

CLUD:

112642978(KCNJ10)

VVP:	112910036(KCNJ10)

VLG:	121472062(KCNJ10)

NPO:	129515283(KCNJ10)

AML:	100479130(KCNJ10)

UMR:	103672051(KCNJ10)

UAR:	123783255(KCNJ10)

ELK:

111138946

LLV:

125085486

MPUF:

101677375(KCNJ10)

MNP:	132025793(KCNJ10)

MLK:	131815352(KCNJ10)

NVS:	122918342(KCNJ10)

MMAQ:

308356073(KCNJ10)

ORO:	101378488(KCNJ10)

EJU:	114199215(KCNJ10)

ZCA:	113933518(KCNJ10)

MLX:	118013634(KCNJ10)

MANO:

123845303(KCNJ10)

NSU:	110573418(KCNJ10)

LWW:	102749394(KCNJ10)

FCA:	101097297(KCNJ10)

PYU:	121015518(KCNJ10)

PCOO:

112851784(KCNJ10)

PBG:	122475598(KCNJ10)

PVIV:

125155080(KCNJ10)

LRUF:

124521660

LGF:	123586152(KCNJ10)

AJU:

106985589

PTG:	102953962(KCNJ10)

PPAD:

109257273(KCNJ10)

PUC:

125925613

PLEZ:

122212152(KCNJ10)

HHV:	120241348(KCNJ10)

CCRU:

144228288(KCNJ10)

BTA:	533343(KCNJ10)

BOM:	102270994(KCNJ10)

BIU:	109578742(KCNJ10)

BJV:	133238611(KCNJ10)

BBUB:

102413391(KCNJ10)

BKE:	129654570(KCNJ10)

BBIS:

104993564(KCNJ10)

CHX:	102186816(KCNJ10)

OAS:	101117892(KCNJ10)

OCAN:

138433930(KCNJ10)

BTAX:

128045300(KCNJ10)

CSUM:

138074541(KCNJ10)

ODA:	120855589(KCNJ10)

CCAD:

122431014(KCNJ10)

MREE:

136176930(KCNJ10)

OVR:	110132107(KCNJ10)

MBEZ:

129541118(KCNJ10) 129541331

SSC:	100627780(KCNJ10)

CFR:	102516595(KCNJ10)

CBAI:

105069513(KCNJ10)

CDK:	105100143(KCNJ10)

VPC:	102541522(KCNJ10)

BACU:

103006737(KCNJ10)

BMUS:

118895479(KCNJ10)

LVE:	103073965(KCNJ10)

OOR:	101289870(KCNJ10)

LALB:

132515896(KCNJ10)

GMF:	115844633(KCNJ10)

DDP:	132438347(KCNJ10)

SCOO:

307175733(KCNJ10)

PCRS:

137219560(KCNJ10)

DLE:	111167191(KCNJ10)

PCAD:

102980919(KCNJ10)

PSIU:

116761818(KCNJ10)

PPHC:

136132743(KCNJ10)

NASI:

112403133(KCNJ10)

HAMP:

307070212(KCNJ10)

ECB:	100058121(KCNJ10)

EPZ:	103551141(KCNJ10)

EAI:	106835752(KCNJ10)

MYB:	102244866(KCNJ10)

MYD:	102757842(KCNJ10)

MMYO:

118673418(KCNJ10)

MLF:	102440207(KCNJ10)

MDT:	132221006(KCNJ10)

MYUM:

138995539(KCNJ10)

PKL:	118721587(KCNJ10)

EFUS:

103297533(KCNJ10)

POTS:

308237840(KCNJ10)

MNA:	107539206(KCNJ10)

DRO:	112314761(KCNJ10)

SHON:

118996420(KCNJ10)

AJM:	119048469(KCNJ10)

PDIC:

114512173(KCNJ10)

PHAS:

123820570(KCNJ10)

MMF:	118637445(KCNJ10)

PPAM:

129062382(KCNJ10)

HAI:	109386507(KCNJ10)

RFQ:	117015157(KCNJ10)

RHII:

308487725(KCNJ10)

PALE:

102885872(KCNJ10)

PGIG:

120584293(KCNJ10)

PVP:	105300719(KCNJ10)

RAY:	107507942(KCNJ10)

MJV:	108403010(KCNJ10)

TOD:	119240102(KCNJ10)

SARA:

101540664(KCNJ10)

SFUM:

130018935(KCNJ10)

SETR:

126013960(KCNJ10)

LAV:	100673497(KCNJ10)

TMU:

101356354

ETF:	101647701(KCNJ10)

DNM:	101410941(KCNJ10)

MDO:	100023256(KCNJ10)

GAS:	123255303(KCNJ10)

SHR:	100915507(KCNJ10)

AFZ:

127559713

PCW:	110203105(KCNJ10)

TVP:	118849181(KCNJ10)

PBRV:

138141974(KCNJ10)

MLAO:

141513364(KCNJ10)

OAA:	100074722(KCNJ10)

TACU:

119947084(KCNJ10)

PCOC:

116238835(KCNJ10)

MGP:	100547455(KCNJ10)

CJO:	107324343(KCNJ10)

NMEL:

110391935(KCNJ10)

AACU:

137845779(KCNJ10) 137849054

OJA:	118159925(KCNJ10)

BCLA:

308454217(KCNJ10)

ACYG:

106029330(KCNJ10)

ABRC:

308183723(KCNJ10)

CATA:

118260481(KCNJ10)

TGU:	100230448(KCNJ10)

LSR:	110479067(KCNJ10)

VMC:	128820390(KCNJ10)

VCHA:

128801241(KCNJ10)

AIB:	137466001 137467967

SCAN:

103825405(KCNJ10)

PMOA:

120504815(KCNJ10)

OTC:	121339038(KCNJ10)

PRUF:

121361887(KCNJ10)

ATRC:

139586980(KCNJ10)

MATE:

118695989(KCNJ10)

MAEN:

136568224(KCNJ10)

GFR:	102045609(KCNJ10)

FAB:	101820781(KCNJ10)

OMA:	130263430(KCNJ10)

PMAJ:

107199603(KCNJ10)

CCAE:

111945702(KCNJ10)

CBRC:

103621399(KCNJ10)

ACOE:

138101052(KCNJ10)

ETL:	114073230(KCNJ10)

ZLE:	135457770(KCNJ10)

ACHL:

103809054(KCNJ10)

SVG:	106863871(KCNJ10)

MMEA:

130588355(KCNJ10)

LCAI:

146421001(KCNJ10)

CFAI:

136303089(KCNJ10)

CCIC:

134055073(KCNJ10)

POCC:

134173091(KCNJ10)

PECH:

308230390(KCNJ10)

FPG:	101915185(KCNJ10)

FCH:	102053477(KCNJ10)

FRS:	119159228(KCNJ10)

ANOC:

141971505(KCNJ10)

SURA:

141936519(KCNJ10)

ACHC:

115346085(KCNJ10)

HALD:

104320203

HLE:	104831340(KCNJ10)

AGEN:

126041035

HHAR:

128145570(KCNJ10)

BBUT:

142036912(KCNJ10)

GCL:

127028782

LDI:	104340957(KCNJ10)

MNB:	103782345(KCNJ10)

DPUB:

104306278(KCNJ10)

EGZ:	104131451(KCNJ10)

NNI:	104012572(KCNJ10)

PLEC:

309600601(KCNJ10)

PARX:

142048281(KCNJ10)

PADL:

103914845(KCNJ10)

AFOR:

103900543(KCNJ10)

CBOR:

142094311(KCNJ10)

CBOY:

140644200(KCNJ10)

MAME:

142420760(KCNJ10)

CLV:	102090363(KCNJ10)

CNIC:

136000179(KCNJ10)

NMAY:

308050822(KCNJ10)

MUI:	104540977(KCNJ10)

PGUU:

104466663(KCNJ10)

PLET:

104628423(KCNJ10)

CMAC:

104479304(KCNJ10)

PCUR:

138732073(KCNJ10)

GAME:

129197851(KCNJ10)

ACAR:

104523664(KCNJ10)

CEUR:

306730069(KCNJ10)

CPEA:

104398474(KCNJ10)

HEK:	139790982(KCNJ10)

CVF:	104282647(KCNJ10)

CRID:

134526068(KCNJ10) 134526069

LMIC:

141734661(KCNJ10)

NARQ:

141475971(KCNJ10)

AAM:	106500062(KCNJ10)

AROW:

112962170(KCNJ10)

NPD:	112955234(KCNJ10)

TGT:	104570245(KCNJ10)

DNE:	112995503(KCNJ10)

SCAM:

104139291(KCNJ10)

ASN:	102377840(KCNJ10)

AMJ:	102566667(KCNJ10)

PSS:	102452967(KCNJ10)

CIZ:	142003894(KCNJ10)

CMY:	102939082(KCNJ10)

CCAY:

125625571(KCNJ10)

LKP:	140902873(KCNJ10)

NDS:	141977319(KCNJ10)

DCC:	119848115(KCNJ10)

CPIC:

101948775(KCNJ10)

TST:	117869793(KCNJ10)

EOB:	135892534(KCNJ10)

CABI:

116834323(KCNJ10)

MRV:	120390030(KCNJ10)

EMQ:	137167475(KCNJ10)

ASAO:

132764227(KCNJ10)

PVT:	110081474(KCNJ10)

SUND:

121915526(KCNJ10)

PBI:	103050707(KCNJ10)

PMUR:

107298216(KCNJ10)

CTIG:

120296673(KCNJ10)

TSR:	106540365(KCNJ10)

PGUT:

117670088(KCNJ10)

PCAE:

139322450(KCNJ10)

APRI:

131186535(KCNJ10)

PTEX:

113449214(KCNJ10)

NSS:	113428759 113428761

VKO:	123019607(KCNJ10)

PMUA:

114586385(KCNJ10)

PRAF:

128404169(KCNJ10)

ZVI:	118076574(KCNJ10)

HCG:	128337157(KCNJ10)

GJA:	107126066(KCNJ10)

STOW:

125439879(KCNJ10)

EMC:	129337653(KCNJ10)

XLA:	108700452(kcnj10.S) 494778(kcnj10.L)

XTR:	779765(kcnj10)

NPR:	108794242(KCNJ10)

RTEM:

120922008(KCNJ10)

ACAT:

141116482(KCNJ10)

PADS:

140342028(KCNJ10)

BBUF:

120981973(KCNJ10)

BGAR:

122923561(KCNJ10)

DTC:	141055636(KCNJ10)

HSQ:	130323716 130324852

PCOB:

134983028(KCNJ10)

PWL:	138268386(KCNJ10)

MUO:	115457620(KCNJ10)

GSH:	117350055(KCNJ10)

DRE:	100329607(kcnj10b) 100538267(kcnj10a)

DAES:

130214847 130231607(kcnj10a)

SRX:	107728032 107730827 107748003 107750225

SANH:

107683767 107684569 107692845 107703868

SGH:	107569585 107570767 107574314 107576513

CCAR:

109057873 109057877 109093098(kcnj10a) 109109663

CAUA:

113045187 113096637 113105426 113105876 113114660

CGIB:

127950832 127961230 128017437

PTET:

122327945 122349303(kcnj10a)

LROH:

127168584(kcnj10a) 127176654

GRF:	141331424(kcnj10a) 141343711 141343962

OMC:	131522543 131544813(kcnj10a)

PPRM:

120469455(kcnj10a) 120471291

RKG:	130076879 130083305(kcnj10a)

SCEP:

307155536(kcnj10a) 307161975(kcnj10b)

PPHX:

306992603(kcnj10a) 306998694(kcnj10b)

MAMB:

125251281 125265353(kcnj10a)

CIDE:

127496565 127515295 127516305

CERY:

137003084 137030602(kcnj10a)

MASI:

127443034 127448982 127453035

TROS:

130553820 130559917(kcnj10a)

TDW:	130417584 130429519(kcnj10a)

MANU:

129437320(kcnj10a) 129443260 141362378

PDAB:

135744219(kcnj10b) 135783634(kcnj10a)

IPU:	108267280 108280182

IFU:	128610344(kcnj10a) 128624438

PHYP:

113533121 113539872(kcnj10)

SMEO:

124387231(kcnj10a) 124402749

TFD:	113645146 113663006

TVC:	132848927(kcnj10a) 132860486

CGAR:

128512787 128529830

NGRA:

132871822 132871866

TRN:	134302522 134312434(kcnj10a)

AMEX:

103021810 103044992(kcnj10a)

CMAO:

118797217 118801746(kcnj10a)

EEE:	113585152 113591457

CHAR:

105891006(kcnj10a) 105903815

SPIL:

134059450 134060174(kcnj10a)

ASAD:

121690394(kcnj10a) 121724565

TRU:	101064149(kcnj10a) 101074826

TFS:	130523211(kcnj10a) 130539366

TNG:	GSTEN00011805G001 GSTEN00014280G001

NCC:	104956808(kcnj10)

TBEN:

117498073(kcnj10a) 117500162

CGOB:

115022184(kcnj10) 115023773

PGEO:

117462509 117464002(kcnj10a)

GACU:

117540920 117555531(kcnj10a)

EMAC:

134866643 134872014(kcnj10a)

ELY:	117246445(kcnj10a) 117272540

EFO:	125884305(kcnj10a) 125902543

PLEP:

121952006 121962062(kcnj10a)

SLUC:

116048861 116053358(kcnj10a)

SVIT:

144526820 144534456(kcnj10a)

ECRA:

117935046(kcnj10a) 117953645

ESP:	116677342 116699316 116706952

PFLV:

114545873 114565477

PFLT:

120568564 120573483

GAT:	120814848 120821254

PPUG:

119206648 119223506

AFB:	129089419 129093611(kcnj10a)

CLUM:

117746045 117747844

PSWI:

130190959 130212004

CANA:

137792126(kcnj10a) 137804970

TBU:	306734034(kcnj10a) 306740918(LOC306740918)

CVE:	137885971(kcnj10a) 137887996

AMIR:

142950876(kcnj10a) 142956896

MSAM:

119901756 119913379

SCHU:

122870532(kcnj10a) 122887486

EARM:

139296542 139305790(kcnj10a)

CUD:	121504198(kcnj10a) 121519612

SPUL:

138600626(kcnj10a) 138611355

LMIX:

132958352(kcnj10a) 132979508

HTC:	141784385(kcnj10a) 141804438

ALAT:

119010943 119026673(kcnj10a)

ASTR:

137590476(kcnj10a) 137612278

PKLU:

139214415 139222698(kcnj10a)

LCO:	104932307 109140114(kcnj10)

AMMM:

307255587(LOC307255587) 307268926(kcnj10a)

MZE:	101477345 101485288

ONL:	100694690 100697257

OAU:

116326670

OLA:	101157996 101162710(kcnj10)

OML:	112151460 112156142

CSAI:

133420693(kcnj10a) 133452518

XMA:	102217970 102232790(kcnj10)

XCO:	114146771(kcnj10) 114157041

XHE:	116721984 116732494

PRET:

103475914(kcnj10a) 103479508

PFOR:

103137983 103145918

PLAI:

106935683 106961177

PMEI:

106910232 106931211

GAF:	122820378 122841134

PPRL:

129377975 129379517

CVG:	107101982 107103199

CTUL:

119779623 119787468

GMU:	124869261 124880707

NFU:	107377024 107383470(kcnj10)

KMR:	108232820 108248448(kcnj10a)

ALIM:

106520791 106528972

NWH:	119415239 119415828

LTU:	140269041 140282119(kcnj10a)

TBT:	306769053(kcnj10a)

MCEP:

125011395 125023851(kcnj10a)

AOCE:

111564909 111571730(kcnj10a)

EJA:	138211893(kcnj10a) 138215779

BFRE:

138626881 138634974(kcnj10a)

LCF:	108883600(kcnj10a) 108884311

CSEM:

103385970 103396802

POV:	109641191(kcnj10) 109646650

SSEN:

122766473(kcnj10a) 122770392

SSOE:

131457032(kcnj10a) 131468648

HHIP:

117778445 117779113

HSP:	118102838(kcnj10a) 118118180

PPLT:

128430306(kcnj10a) 128455181

SMAU:

118284377(kcnj10a) 118310460

SDU:	111231065(kcnj10) 111235671

SLAL:

111647235 111668457(kcnj10)

XGL:	120797484(kcnj10a) 120798491

HCQ:	109508335 109529513

SSCV:

125974434 125985198

SBIA:

133494936 133510888

PEE:	133397807 133411591(kcnj10a)

PTAO:

133472826 133489168

BPEC:

110170801 110171936

ENY:	140355963 140371905(kcnj10a)

MALB:

109951578 109971471

BSPL:

114844899 114848305(kcnj10a)

SJO:	128368904 128383944(kcnj10a)

SSCO:

133990625 134005645(kcnj10a)

TTY:	137174663(kcnj10a) 137194559

GMH:	115529876 115549090

ZFA:	307238521(LOC307238521) 307247568(kcnj10a)

SASA:

106578022 106600497 106608990

STRU:

115169303 115169304 115194502 115198476

OTW:	112214583 112226572

OMY:	110500423 110508321 110532934

OGO:	124007631 124013957 124041628

ONE:	115102827 115133382 115137940

OKI:	109872336 109896915 109906214

OKE:	118367986 118394946

OMM:	135510442 135516175 135559019

OCLA:

139376372 139379393 139415973

SALP:

111952546 111979721

SNH:	120020752 120030711 120049275

SFON:

129824463 129835381 129865524

CCLU:

121571352 121581283 123483153

ELS:	105022857 105030129

OEP:	134009580(kcnj10a) 134037016

SFM:	108926084 108937831(kcnj10)

PKI:	111833161(kcnj10)

AANG:

AROT:

CCOG:

LOC:

PSPA:

ARUT:

PSEX:

LCM:	102358335(KCNJ10)

CMK:

RTP:

CPLA:

CPUN:

HOC:

LERI:

HAKA:

PMRN:

116948101(KCNJ10) 116954585 116955766

LRJ:	133342020 133347812 133357673

SOY:

115883582

» show all

Reference

PMID:8995301

Authors

Shuck ME, Piser TM, Bock JH, Slightom JL, Lee KS, Bienkowski MJ

Title

Cloning and characterization of two K+ inward rectifier (Kir) 1.1 potassium channel homologs from human kidney (Kir1.2 and Kir1.3).

Journal

J Biol Chem 272:586-93 (1997)
DOI:10.1074/jbc.272.1.586

Sequence

[hsa:3766]

Reference

PMID:21106816

Authors

Chever O, Djukic B, McCarthy KD, Amzica F

Title

Implication of Kir4.1 channel in excess potassium clearance: an in vivo study on anesthetized glial-conditional Kir4.1 knock-out mice.

Journal

J Neurosci 30:15769-77 (2010)
DOI:10.1523/JNEUROSCI.2078-10.2010

Sequence

[hsa:3766]

LinkDB

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